Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | SANA_TNF_SIGNALING_UP |
| Enrichment Score (ES) | 0.836212 |
| Normalized Enrichment Score (NES) | 2.1247323 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 17 | 4.863 | 0.0343 | Yes |
| 2 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 19 | 4.836 | 0.0689 | Yes |
| 3 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 20 | 4.828 | 0.1034 | Yes |
| 4 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 21 | 4.823 | 0.1379 | Yes |
| 5 | PLA1A | phospholipase A1 member A [Source:HGNC Symbol;Acc:HGNC:17661] | 22 | 4.815 | 0.1723 | Yes |
| 6 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 29 | 4.760 | 0.2062 | Yes |
| 7 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 40 | 4.584 | 0.2387 | Yes |
| 8 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 46 | 4.543 | 0.2710 | Yes |
| 9 | IFIH1 | interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873] | 57 | 4.431 | 0.3024 | Yes |
| 10 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 84 | 4.181 | 0.3316 | Yes |
| 11 | SERPINE1 | serpin family E member 1 [Source:HGNC Symbol;Acc:HGNC:8583] | 100 | 4.044 | 0.3601 | Yes |
| 12 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 118 | 3.942 | 0.3879 | Yes |
| 13 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 128 | 3.902 | 0.4155 | Yes |
| 14 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 151 | 3.729 | 0.4416 | Yes |
| 15 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 154 | 3.699 | 0.4680 | Yes |
| 16 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 159 | 3.663 | 0.4941 | Yes |
| 17 | ITGAV | integrin subunit alpha V [Source:HGNC Symbol;Acc:HGNC:6150] | 161 | 3.659 | 0.5202 | Yes |
| 18 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 168 | 3.624 | 0.5460 | Yes |
| 19 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 174 | 3.614 | 0.5717 | Yes |
| 20 | TAPBP | TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566] | 215 | 3.342 | 0.5945 | Yes |
| 21 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 216 | 3.338 | 0.6184 | Yes |
| 22 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 228 | 3.279 | 0.6415 | Yes |
| 23 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 276 | 3.036 | 0.6619 | Yes |
| 24 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 300 | 2.921 | 0.6822 | Yes |
| 25 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 404 | 2.597 | 0.6980 | Yes |
| 26 | DNAJA1 | DnaJ heat shock protein family (Hsp40) member A1 [Source:HGNC Symbol;Acc:HGNC:5229] | 456 | 2.459 | 0.7142 | Yes |
| 27 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 486 | 2.398 | 0.7306 | Yes |
| 28 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 580 | 2.164 | 0.7435 | Yes |
| 29 | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925] | 713 | 1.947 | 0.7539 | Yes |
| 30 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 731 | 1.925 | 0.7672 | Yes |
| 31 | HLA-E | major histocompatibility complex, class I, E [Source:HGNC Symbol;Acc:HGNC:4962] | 783 | 1.845 | 0.7790 | Yes |
| 32 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 802 | 1.811 | 0.7915 | Yes |
| 33 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 858 | 1.747 | 0.8025 | Yes |
| 34 | HLA-B | major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:HGNC:4932] | 1095 | 1.472 | 0.8066 | Yes |
| 35 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 1150 | 1.427 | 0.8154 | Yes |
| 36 | FTH1 | ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976] | 1368 | 1.266 | 0.8186 | Yes |
| 37 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 1391 | 1.252 | 0.8269 | Yes |
| 38 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 1464 | 1.209 | 0.8336 | Yes |
| 39 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 1772 | 1.050 | 0.8328 | Yes |
| 40 | LIPG | lipase G, endothelial type [Source:HGNC Symbol;Acc:HGNC:6623] | 1910 | 0.992 | 0.8362 | Yes |
| 41 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 2766 | 0.661 | 0.8178 | No |
| 42 | RABL3 | RAB, member of RAS oncogene family like 3 [Source:HGNC Symbol;Acc:HGNC:18072] | 3261 | 0.536 | 0.8083 | No |
| 43 | SPAG9 | sperm associated antigen 9 [Source:HGNC Symbol;Acc:HGNC:14524] | 4139 | 0.352 | 0.7871 | No |
| 44 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 4573 | 0.262 | 0.7773 | No |
| 45 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 4688 | 0.239 | 0.7759 | No |
| 46 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 4853 | 0.209 | 0.7730 | No |
| 47 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6013 | 0.000 | 0.7417 | No |
| 48 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6046 | 0.000 | 0.7408 | No |
| 49 | PDGFRL | platelet derived growth factor receptor like [Source:HGNC Symbol;Acc:HGNC:8805] | 7178 | 0.000 | 0.7103 | No |
| 50 | APOL1 | apolipoprotein L1 [Source:HGNC Symbol;Acc:HGNC:618] | 9785 | 0.000 | 0.6398 | No |
| 51 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 9787 | 0.000 | 0.6398 | No |
| 52 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10448 | 0.000 | 0.6220 | No |
| 53 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 10800 | 0.000 | 0.6125 | No |
| 54 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 10908 | 0.000 | 0.6096 | No |
| 55 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12304 | 0.000 | 0.5719 | No |
| 56 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 12636 | 0.000 | 0.5630 | No |
| 57 | IL32 | interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830] | 13666 | 0.000 | 0.5352 | No |
| 58 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13720 | 0.000 | 0.5337 | No |
| 59 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18189 | 0.000 | 0.4130 | No |
| 60 | CTHRC1 | collagen triple helix repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:18831] | 18872 | 0.000 | 0.3946 | No |
| 61 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19366 | 0.000 | 0.3812 | No |
| 62 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19371 | 0.000 | 0.3811 | No |
| 63 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19382 | 0.000 | 0.3809 | No |
| 64 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 20835 | 0.000 | 0.3416 | No |
| 65 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22826 | 0.000 | 0.2879 | No |
| 66 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22828 | 0.000 | 0.2878 | No |
| 67 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22836 | 0.000 | 0.2876 | No |
| 68 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 23524 | 0.000 | 0.2691 | No |
| 69 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 23589 | 0.000 | 0.2674 | No |
| 70 | ANO9 | anoctamin 9 [Source:HGNC Symbol;Acc:HGNC:20679] | 24947 | 0.000 | 0.2307 | No |
| 71 | SSPN | sarcospan [Source:HGNC Symbol;Acc:HGNC:11322] | 26975 | 0.000 | 0.1759 | No |
| 72 | RAC3 | Rac family small GTPase 3 [Source:HGNC Symbol;Acc:HGNC:9803] | 28257 | -0.143 | 0.1423 | No |
| 73 | C1QTNF1 | C1q and TNF related 1 [Source:HGNC Symbol;Acc:HGNC:14324] | 29089 | -0.264 | 0.1218 | No |
| 74 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 29779 | -0.366 | 0.1058 | No |
| 75 | ATP13A3 | ATPase 13A3 [Source:HGNC Symbol;Acc:HGNC:24113] | 30894 | -0.541 | 0.0795 | No |
| 76 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 30895 | -0.541 | 0.0834 | No |
| 77 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 31304 | -0.611 | 0.0767 | No |
| 78 | NCEH1 | neutral cholesterol ester hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:29260] | 32155 | -0.796 | 0.0595 | No |
| 79 | BPGM | bisphosphoglycerate mutase [Source:HGNC Symbol;Acc:HGNC:1093] | 34258 | -1.470 | 0.0132 | No |
| 80 | DRAM1 | DNA damage regulated autophagy modulator 1 [Source:HGNC Symbol;Acc:HGNC:25645] | 34293 | -1.484 | 0.0229 | No |
| 81 | RHOB | ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668] | 34851 | -1.721 | 0.0201 | No |
| 82 | OXR1 | oxidation resistance 1 [Source:HGNC Symbol;Acc:HGNC:15822] | 35633 | -2.223 | 0.0149 | No |
| 83 | SMAD3 | SMAD family member 3 [Source:HGNC Symbol;Acc:HGNC:6769] | 36689 | -3.416 | 0.0108 | No |
