Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | SEKI_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.8559826 |
| Normalized Enrichment Score (NES) | 2.1210473 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 0 | 4.995 | 0.0340 | Yes |
| 2 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 15 | 4.872 | 0.0669 | Yes |
| 3 | GBP6 | guanylate binding protein family member 6 [Source:HGNC Symbol;Acc:HGNC:25395] | 16 | 4.866 | 0.1000 | Yes |
| 4 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 23 | 4.787 | 0.1325 | Yes |
| 5 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 31 | 4.715 | 0.1644 | Yes |
| 6 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 40 | 4.584 | 0.1954 | Yes |
| 7 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 51 | 4.480 | 0.2257 | Yes |
| 8 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 73 | 4.268 | 0.2542 | Yes |
| 9 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 87 | 4.161 | 0.2822 | Yes |
| 10 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 89 | 4.123 | 0.3103 | Yes |
| 11 | ZC3H12A | zinc finger CCCH-type containing 12A [Source:HGNC Symbol;Acc:HGNC:26259] | 115 | 3.959 | 0.3366 | Yes |
| 12 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 128 | 3.902 | 0.3628 | Yes |
| 13 | RND1 | Rho family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:18314] | 134 | 3.866 | 0.3890 | Yes |
| 14 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 151 | 3.729 | 0.4140 | Yes |
| 15 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 159 | 3.663 | 0.4388 | Yes |
| 16 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 160 | 3.661 | 0.4637 | Yes |
| 17 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 176 | 3.589 | 0.4878 | Yes |
| 18 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 180 | 3.568 | 0.5120 | Yes |
| 19 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 216 | 3.338 | 0.5338 | Yes |
| 20 | SLC4A7 | solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033] | 217 | 3.330 | 0.5565 | Yes |
| 21 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 228 | 3.279 | 0.5786 | Yes |
| 22 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 238 | 3.232 | 0.6003 | Yes |
| 23 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 241 | 3.211 | 0.6222 | Yes |
| 24 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 279 | 3.025 | 0.6418 | Yes |
| 25 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 300 | 2.921 | 0.6612 | Yes |
| 26 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 336 | 2.805 | 0.6793 | Yes |
| 27 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 404 | 2.597 | 0.6952 | Yes |
| 28 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 444 | 2.489 | 0.7111 | Yes |
| 29 | ZMYND15 | zinc finger MYND-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20997] | 463 | 2.446 | 0.7273 | Yes |
| 30 | SLC11A2 | solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908] | 539 | 2.240 | 0.7405 | Yes |
| 31 | SH3PXD2B | SH3 and PX domains 2B [Source:HGNC Symbol;Acc:HGNC:29242] | 553 | 2.216 | 0.7553 | Yes |
| 32 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 609 | 2.131 | 0.7683 | Yes |
| 33 | MAFF | MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] | 611 | 2.130 | 0.7828 | Yes |
| 34 | JDP2 | Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546] | 632 | 2.087 | 0.7965 | Yes |
| 35 | GSAP | gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042] | 659 | 2.026 | 0.8096 | Yes |
| 36 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 681 | 1.981 | 0.8225 | Yes |
| 37 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 802 | 1.811 | 0.8316 | Yes |
| 38 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 850 | 1.758 | 0.8423 | Yes |
| 39 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 858 | 1.747 | 0.8540 | Yes |
| 40 | FAS | Fas cell surface death receptor [Source:HGNC Symbol;Acc:HGNC:11920] | 1320 | 1.304 | 0.8505 | Yes |
| 41 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 1427 | 1.232 | 0.8560 | Yes |
| 42 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 1716 | 1.080 | 0.8556 | No |
| 43 | EXOC3L4 | exocyst complex component 3 like 4 [Source:HGNC Symbol;Acc:HGNC:20120] | 2488 | 0.745 | 0.8398 | No |
| 44 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 4853 | 0.209 | 0.7774 | No |
| 45 | SELE | selectin E [Source:HGNC Symbol;Acc:HGNC:10718] | 6805 | 0.000 | 0.7247 | No |
| 46 | PRRX1 | paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142] | 8250 | 0.000 | 0.6856 | No |
| 47 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8385 | 0.000 | 0.6820 | No |
| 48 | NGFR | nerve growth factor receptor [Source:HGNC Symbol;Acc:HGNC:7809] | 10046 | 0.000 | 0.6372 | No |
| 49 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 10908 | 0.000 | 0.6139 | No |
| 50 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11211 | 0.000 | 0.6057 | No |
| 51 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13720 | 0.000 | 0.5380 | No |
| 52 | LRATD1 | LRAT domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20743] | 17968 | 0.000 | 0.4232 | No |
| 53 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18189 | 0.000 | 0.4173 | No |
| 54 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18810 | 0.000 | 0.4005 | No |
| 55 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 18928 | 0.000 | 0.3974 | No |
| 56 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19366 | 0.000 | 0.3856 | No |
| 57 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19380 | 0.000 | 0.3852 | No |
| 58 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19382 | 0.000 | 0.3852 | No |
| 59 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 19782 | 0.000 | 0.3744 | No |
| 60 | ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif 7 [Source:HGNC Symbol;Acc:HGNC:223] | 19966 | 0.000 | 0.3695 | No |
| 61 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 22010 | 0.000 | 0.3143 | No |
| 62 | EGFR | epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236] | 22045 | 0.000 | 0.3134 | No |
| 63 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22828 | 0.000 | 0.2922 | No |
| 64 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22836 | 0.000 | 0.2920 | No |
| 65 | SCHIP1 | schwannomin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:15678] | 23390 | 0.000 | 0.2771 | No |
| 66 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 26653 | 0.000 | 0.1890 | No |
| 67 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 27646 | -0.053 | 0.1625 | No |
| 68 | CEMIP2 | cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869] | 29047 | -0.257 | 0.1265 | No |
| 69 | BIRC2 | baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590] | 30407 | -0.461 | 0.0929 | No |
| 70 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 32072 | -0.773 | 0.0532 | No |
| 71 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 32477 | -0.881 | 0.0483 | No |
| 72 | NEURL3 | neuralized E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:25162] | 32801 | -0.973 | 0.0462 | No |
| 73 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 33826 | -1.312 | 0.0275 | No |
| 74 | SLCO4A1 | solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953] | 34249 | -1.466 | 0.0261 | No |
| 75 | BMP2 | bone morphogenetic protein 2 [Source:HGNC Symbol;Acc:HGNC:1069] | 34630 | -1.614 | 0.0268 | No |
| 76 | RFX5 | regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986] | 34807 | -1.701 | 0.0336 | No |
| 77 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 34877 | -1.739 | 0.0436 | No |
| 78 | TJP2 | tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828] | 35803 | -2.372 | 0.0348 | No |
