Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | WHITEFORD_PEDIATRIC_CANCER_MARKERS |
| Enrichment Score (ES) | -0.8013507 |
| Normalized Enrichment Score (NES) | -1.6760511 |
| Nominal p-value | 0.0 |
| FDR q-value | 7.976887E-4 |
| FWER p-Value | 0.014 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 34 | 4.688 | 0.0200 | No |
| 2 | BCAT1 | branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976] | 400 | 2.610 | 0.0218 | No |
| 3 | NME1 | NME/NM23 nucleoside diphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:7849] | 793 | 1.831 | 0.0194 | No |
| 4 | MLLT11 | MLLT11 transcription factor 7 cofactor [Source:HGNC Symbol;Acc:HGNC:16997] | 1544 | 1.174 | 0.0043 | No |
| 5 | CDK6 | cyclin dependent kinase 6 [Source:HGNC Symbol;Acc:HGNC:1777] | 2170 | 0.867 | -0.0087 | No |
| 6 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2428 | 0.770 | -0.0122 | No |
| 7 | EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3288] | 3541 | 0.471 | -0.0402 | No |
| 8 | EIF4A1 | eukaryotic translation initiation factor 4A1 [Source:HGNC Symbol;Acc:HGNC:3282] | 3687 | 0.441 | -0.0421 | No |
| 9 | JPT1 | Jupiter microtubule associated homolog 1 [Source:HGNC Symbol;Acc:HGNC:14569] | 4336 | 0.310 | -0.0583 | No |
| 10 | CCNT1 | cyclin T1 [Source:HGNC Symbol;Acc:HGNC:1599] | 5288 | 0.132 | -0.0834 | No |
| 11 | ILF2 | interleukin enhancer binding factor 2 [Source:HGNC Symbol;Acc:HGNC:6037] | 5852 | 0.021 | -0.0986 | No |
| 12 | GPX7 | glutathione peroxidase 7 [Source:HGNC Symbol;Acc:HGNC:4559] | 9202 | 0.000 | -0.1891 | No |
| 13 | H4C3 | H4 clustered histone 3 [Source:HGNC Symbol;Acc:HGNC:4787] | 9874 | 0.000 | -0.2073 | No |
| 14 | KLKB1 | kallikrein B1 [Source:HGNC Symbol;Acc:HGNC:6371] | 10846 | 0.000 | -0.2335 | No |
| 15 | TMEFF1 | transmembrane protein with EGF like and two follistatin like domains 1 [Source:HGNC Symbol;Acc:HGNC:11866] | 15478 | 0.000 | -0.3588 | No |
| 16 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16648 | 0.000 | -0.3904 | No |
| 17 | TWIST1 | twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428] | 17174 | 0.000 | -0.4046 | No |
| 18 | GABRB2 | gamma-aminobutyric acid type A receptor subunit beta2 [Source:HGNC Symbol;Acc:HGNC:4082] | 19855 | 0.000 | -0.4771 | No |
| 19 | SNORD22 | small nucleolar RNA, C/D box 22 [Source:HGNC Symbol;Acc:HGNC:10145] | 22244 | 0.000 | -0.5417 | No |
| 20 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 23956 | 0.000 | -0.5880 | No |
| 21 | SOX4 | SRY-box transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:11200] | 25999 | 0.000 | -0.6432 | No |
| 22 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26019 | 0.000 | -0.6437 | No |
| 23 | GGH | gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] | 27673 | -0.057 | -0.6881 | No |
| 24 | ZNF300 | zinc finger protein 300 [Source:HGNC Symbol;Acc:HGNC:13091] | 27914 | -0.091 | -0.6942 | No |
| 25 | MFN2 | mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877] | 28235 | -0.139 | -0.7023 | No |
| 26 | PSAT1 | phosphoserine aminotransferase 1 [Source:HGNC Symbol;Acc:HGNC:19129] | 28687 | -0.200 | -0.7136 | No |
| 27 | CDC25A | cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725] | 29004 | -0.250 | -0.7210 | No |
| 28 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 29048 | -0.257 | -0.7210 | No |
| 29 | ADGRL3 | adhesion G protein-coupled receptor L3 [Source:HGNC Symbol;Acc:HGNC:20974] | 29234 | -0.286 | -0.7247 | No |
| 30 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 30719 | -0.514 | -0.7626 | No |
| 31 | RRP1 | ribosomal RNA processing 1 [Source:HGNC Symbol;Acc:HGNC:18785] | 30965 | -0.552 | -0.7667 | No |
| 32 | ENO1 | enolase 1 [Source:HGNC Symbol;Acc:HGNC:3350] | 31071 | -0.571 | -0.7670 | No |
| 33 | SNRNP200 | small nuclear ribonucleoprotein U5 subunit 200 [Source:HGNC Symbol;Acc:HGNC:30859] | 31777 | -0.704 | -0.7830 | No |
| 34 | ZMYM2 | zinc finger MYM-type containing 2 [Source:HGNC Symbol;Acc:HGNC:12989] | 31846 | -0.714 | -0.7816 | No |
| 35 | ILF3 | interleukin enhancer binding factor 3 [Source:HGNC Symbol;Acc:HGNC:6038] | 31856 | -0.718 | -0.7786 | No |
| 36 | POLQ | DNA polymerase theta [Source:HGNC Symbol;Acc:HGNC:9186] | 31932 | -0.738 | -0.7774 | No |
| 37 | MND1 | meiotic nuclear divisions 1 [Source:HGNC Symbol;Acc:HGNC:24839] | 32109 | -0.782 | -0.7786 | No |
| 38 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32418 | -0.869 | -0.7831 | No |
| 39 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32753 | -0.958 | -0.7879 | No |
| 40 | RCC2 | regulator of chromosome condensation 2 [Source:HGNC Symbol;Acc:HGNC:30297] | 33121 | -1.069 | -0.7930 | No |
| 41 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33208 | -1.098 | -0.7904 | No |
| 42 | LMNB2 | lamin B2 [Source:HGNC Symbol;Acc:HGNC:6638] | 33381 | -1.154 | -0.7899 | No |
| 43 | RECQL4 | RecQ like helicase 4 [Source:HGNC Symbol;Acc:HGNC:9949] | 33676 | -1.259 | -0.7923 | No |
| 44 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 34013 | -1.377 | -0.7952 | Yes |
| 45 | ADCY3 | adenylate cyclase 3 [Source:HGNC Symbol;Acc:HGNC:234] | 34056 | -1.390 | -0.7901 | Yes |
| 46 | CENPU | centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348] | 34297 | -1.486 | -0.7900 | Yes |
| 47 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 34335 | -1.502 | -0.7843 | Yes |
| 48 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34381 | -1.518 | -0.7787 | Yes |
| 49 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141] | 34513 | -1.567 | -0.7753 | Yes |
| 50 | ZNF367 | zinc finger protein 367 [Source:HGNC Symbol;Acc:HGNC:18320] | 34624 | -1.612 | -0.7710 | Yes |
| 51 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34638 | -1.617 | -0.7642 | Yes |
| 52 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34684 | -1.643 | -0.7581 | Yes |
| 53 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 34697 | -1.649 | -0.7510 | Yes |
| 54 | PON3 | paraoxonase 3 [Source:HGNC Symbol;Acc:HGNC:9206] | 34872 | -1.734 | -0.7480 | Yes |
| 55 | CDK4 | cyclin dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773] | 34916 | -1.761 | -0.7413 | Yes |
| 56 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35101 | -1.865 | -0.7379 | Yes |
| 57 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35138 | -1.892 | -0.7305 | Yes |
| 58 | NUDT1 | nudix hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:8048] | 35141 | -1.895 | -0.7221 | Yes |
| 59 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35192 | -1.927 | -0.7148 | Yes |
| 60 | CCDC34 | coiled-coil domain containing 34 [Source:HGNC Symbol;Acc:HGNC:25079] | 35240 | -1.957 | -0.7073 | Yes |
| 61 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35290 | -1.989 | -0.6998 | Yes |
| 62 | CENPN | centromere protein N [Source:HGNC Symbol;Acc:HGNC:30873] | 35359 | -2.031 | -0.6926 | Yes |
| 63 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35380 | -2.050 | -0.6839 | Yes |
| 64 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35407 | -2.067 | -0.6754 | Yes |
| 65 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 35480 | -2.112 | -0.6679 | Yes |
| 66 | HAUS1 | HAUS augmin like complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:25174] | 35501 | -2.124 | -0.6590 | Yes |
| 67 | RNASEH2A | ribonuclease H2 subunit A [Source:HGNC Symbol;Acc:HGNC:18518] | 35592 | -2.193 | -0.6516 | Yes |
| 68 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 35605 | -2.200 | -0.6421 | Yes |
| 69 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35807 | -2.374 | -0.6370 | Yes |
| 70 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35830 | -2.402 | -0.6269 | Yes |
| 71 | SLC25A40 | solute carrier family 25 member 40 [Source:HGNC Symbol;Acc:HGNC:29680] | 35921 | -2.477 | -0.6182 | Yes |
| 72 | MEX3B | mex-3 RNA binding family member B [Source:HGNC Symbol;Acc:HGNC:25297] | 35927 | -2.480 | -0.6073 | Yes |
| 73 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35941 | -2.490 | -0.5965 | Yes |
| 74 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35981 | -2.530 | -0.5863 | Yes |
| 75 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 36068 | -2.625 | -0.5769 | Yes |
| 76 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 36076 | -2.633 | -0.5653 | Yes |
| 77 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36083 | -2.637 | -0.5537 | Yes |
| 78 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36125 | -2.680 | -0.5429 | Yes |
| 79 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36138 | -2.694 | -0.5312 | Yes |
| 80 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36139 | -2.694 | -0.5191 | Yes |
| 81 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36199 | -2.753 | -0.5084 | Yes |
| 82 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36208 | -2.759 | -0.4963 | Yes |
| 83 | MYCN | MYCN proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7559] | 36233 | -2.784 | -0.4846 | Yes |
| 84 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36251 | -2.795 | -0.4725 | Yes |
| 85 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36260 | -2.803 | -0.4602 | Yes |
| 86 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 36273 | -2.821 | -0.4480 | Yes |
| 87 | ATAD2 | ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123] | 36303 | -2.848 | -0.4360 | Yes |
| 88 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36357 | -2.930 | -0.4244 | Yes |
| 89 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36361 | -2.936 | -0.4114 | Yes |
| 90 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36367 | -2.940 | -0.3984 | Yes |
| 91 | UHRF1 | ubiquitin like with PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:12556] | 36415 | -3.003 | -0.3862 | Yes |
| 92 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36421 | -3.011 | -0.3729 | Yes |
| 93 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36439 | -3.036 | -0.3598 | Yes |
| 94 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36457 | -3.057 | -0.3466 | Yes |
| 95 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36461 | -3.062 | -0.3331 | Yes |
| 96 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36476 | -3.083 | -0.3197 | Yes |
| 97 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36508 | -3.121 | -0.3066 | Yes |
| 98 | PAFAH1B3 | platelet activating factor acetylhydrolase 1b catalytic subunit 3 [Source:HGNC Symbol;Acc:HGNC:8576] | 36544 | -3.185 | -0.2933 | Yes |
| 99 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36546 | -3.187 | -0.2791 | Yes |
| 100 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36575 | -3.228 | -0.2654 | Yes |
| 101 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36629 | -3.321 | -0.2521 | Yes |
| 102 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36635 | -3.330 | -0.2373 | Yes |
| 103 | CDCA2 | cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623] | 36656 | -3.362 | -0.2229 | Yes |
| 104 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36660 | -3.369 | -0.2079 | Yes |
| 105 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36691 | -3.417 | -0.1934 | Yes |
| 106 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36709 | -3.440 | -0.1785 | Yes |
| 107 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36780 | -3.580 | -0.1645 | Yes |
| 108 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36784 | -3.594 | -0.1485 | Yes |
| 109 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36802 | -3.632 | -0.1327 | Yes |
| 110 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36808 | -3.649 | -0.1166 | Yes |
| 111 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 36812 | -3.660 | -0.1003 | Yes |
| 112 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36817 | -3.672 | -0.0840 | Yes |
| 113 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36841 | -3.749 | -0.0679 | Yes |
| 114 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36873 | -3.821 | -0.0517 | Yes |
| 115 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36939 | -3.976 | -0.0357 | Yes |
| 116 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 37006 | -4.236 | -0.0186 | Yes |
| 117 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37070 | -4.666 | 0.0005 | Yes |
