Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | ZHAN_MULTIPLE_MYELOMA_PR_UP |
| Enrichment Score (ES) | -0.8817333 |
| Normalized Enrichment Score (NES) | -1.6822087 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.590494E-4 |
| FWER p-Value | 0.014 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TSR1 | TSR1 ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:25542] | 1158 | 1.422 | -0.0184 | No |
| 2 | GAGE1 | G antigen 1 [Source:HGNC Symbol;Acc:HGNC:4098] | 18722 | 0.000 | -0.4925 | No |
| 3 | FAM72C | family with sequence similarity 72 member C [Source:HGNC Symbol;Acc:HGNC:30602] | 22269 | 0.000 | -0.5883 | No |
| 4 | MAGEA1 | MAGE family member A1 [Source:HGNC Symbol;Acc:HGNC:6796] | 26534 | 0.000 | -0.7034 | No |
| 5 | MAGEA3 | MAGE family member A3 [Source:HGNC Symbol;Acc:HGNC:6801] | 26540 | 0.000 | -0.7035 | No |
| 6 | MPC2 | mitochondrial pyruvate carrier 2 [Source:HGNC Symbol;Acc:HGNC:24515] | 31494 | -0.651 | -0.8313 | No |
| 7 | SLC19A1 | solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937] | 32124 | -0.785 | -0.8412 | No |
| 8 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32418 | -0.869 | -0.8413 | No |
| 9 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 33916 | -1.342 | -0.8696 | Yes |
| 10 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 34335 | -1.502 | -0.8674 | Yes |
| 11 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34381 | -1.518 | -0.8549 | Yes |
| 12 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 34678 | -1.641 | -0.8481 | Yes |
| 13 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34837 | -1.712 | -0.8370 | Yes |
| 14 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35064 | -1.841 | -0.8265 | Yes |
| 15 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35131 | -1.888 | -0.8112 | Yes |
| 16 | CCDC34 | coiled-coil domain containing 34 [Source:HGNC Symbol;Acc:HGNC:25079] | 35240 | -1.957 | -0.7965 | Yes |
| 17 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35380 | -2.050 | -0.7818 | Yes |
| 18 | SPC24 | SPC24 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:26913] | 35411 | -2.069 | -0.7640 | Yes |
| 19 | ZWILCH | zwilch kinetochore protein [Source:HGNC Symbol;Acc:HGNC:25468] | 35412 | -2.072 | -0.7453 | Yes |
| 20 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 35605 | -2.200 | -0.7306 | Yes |
| 21 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35830 | -2.402 | -0.7150 | Yes |
| 22 | CENPL | centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879] | 35885 | -2.448 | -0.6944 | Yes |
| 23 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 35933 | -2.484 | -0.6733 | Yes |
| 24 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35941 | -2.490 | -0.6511 | Yes |
| 25 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35981 | -2.530 | -0.6293 | Yes |
| 26 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36065 | -2.624 | -0.6079 | Yes |
| 27 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36239 | -2.787 | -0.5875 | Yes |
| 28 | SKA1 | spindle and kinetochore associated complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28109] | 36321 | -2.885 | -0.5637 | Yes |
| 29 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36357 | -2.930 | -0.5382 | Yes |
| 30 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36367 | -2.940 | -0.5119 | Yes |
| 31 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36461 | -3.062 | -0.4869 | Yes |
| 32 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36476 | -3.083 | -0.4595 | Yes |
| 33 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36654 | -3.353 | -0.4340 | Yes |
| 34 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36691 | -3.417 | -0.4042 | Yes |
| 35 | DSCC1 | DNA replication and sister chromatid cohesion 1 [Source:HGNC Symbol;Acc:HGNC:24453] | 36699 | -3.424 | -0.3735 | Yes |
| 36 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36802 | -3.632 | -0.3436 | Yes |
| 37 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36808 | -3.649 | -0.3108 | Yes |
| 38 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36817 | -3.672 | -0.2779 | Yes |
| 39 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36828 | -3.703 | -0.2448 | Yes |
| 40 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36841 | -3.749 | -0.2114 | Yes |
| 41 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36873 | -3.821 | -0.1778 | Yes |
| 42 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36920 | -3.941 | -0.1435 | Yes |
| 43 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36939 | -3.976 | -0.1082 | Yes |
| 44 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36953 | -4.019 | -0.0723 | Yes |
| 45 | DEPDC1B | DEP domain containing 1B [Source:HGNC Symbol;Acc:HGNC:24902] | 36995 | -4.190 | -0.0356 | Yes |
| 46 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 37006 | -4.236 | 0.0023 | Yes |
