Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | SRF_01 |
| Enrichment Score (ES) | 0.60550034 |
| Normalized Enrichment Score (NES) | 1.37785 |
| Nominal p-value | 0.024242423 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 31 | 4.715 | 0.0881 | Yes |
| 2 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 156 | 3.689 | 0.1543 | Yes |
| 3 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 227 | 3.279 | 0.2142 | Yes |
| 4 | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3797] | 252 | 3.167 | 0.2733 | Yes |
| 5 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 352 | 2.745 | 0.3223 | Yes |
| 6 | HOXB4 | homeobox B4 [Source:HGNC Symbol;Acc:HGNC:5115] | 432 | 2.521 | 0.3677 | Yes |
| 7 | ACTN1 | actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163] | 447 | 2.480 | 0.4141 | Yes |
| 8 | WDR1 | WD repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:12754] | 531 | 2.277 | 0.4548 | Yes |
| 9 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 829 | 1.780 | 0.4804 | Yes |
| 10 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 856 | 1.749 | 0.5126 | Yes |
| 11 | PFN1 | profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881] | 1099 | 1.468 | 0.5338 | Yes |
| 12 | ACTR3 | actin related protein 3 [Source:HGNC Symbol;Acc:HGNC:170] | 1105 | 1.461 | 0.5612 | Yes |
| 13 | CFL1 | cofilin 1 [Source:HGNC Symbol;Acc:HGNC:1874] | 1161 | 1.419 | 0.5865 | Yes |
| 14 | MYL6 | myosin light chain 6 [Source:HGNC Symbol;Acc:HGNC:7587] | 1350 | 1.278 | 0.6055 | Yes |
| 15 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 3575 | 0.463 | 0.5542 | No |
| 16 | MYH11 | myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569] | 3618 | 0.454 | 0.5616 | No |
| 17 | SCOC | short coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:20335] | 5499 | 0.093 | 0.5126 | No |
| 18 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796] | 5964 | 0.001 | 0.5001 | No |
| 19 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 7756 | 0.000 | 0.4517 | No |
| 20 | CALD1 | caldesmon 1 [Source:HGNC Symbol;Acc:HGNC:1441] | 8398 | 0.000 | 0.4344 | No |
| 21 | NPAS4 | neuronal PAS domain protein 4 [Source:HGNC Symbol;Acc:HGNC:18983] | 9485 | 0.000 | 0.4051 | No |
| 22 | SUSD1 | sushi domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25413] | 9939 | 0.000 | 0.3929 | No |
| 23 | PRM1 | protamine 1 [Source:HGNC Symbol;Acc:HGNC:9447] | 11280 | 0.000 | 0.3567 | No |
| 24 | TNMD | tenomodulin [Source:HGNC Symbol;Acc:HGNC:17757] | 14767 | 0.000 | 0.2626 | No |
| 25 | CA3 | carbonic anhydrase 3 [Source:HGNC Symbol;Acc:HGNC:1374] | 15638 | 0.000 | 0.2391 | No |
| 26 | PHOX2B | paired like homeobox 2B [Source:HGNC Symbol;Acc:HGNC:9143] | 16234 | 0.000 | 0.2230 | No |
| 27 | GPR20 | G protein-coupled receptor 20 [Source:HGNC Symbol;Acc:HGNC:4475] | 17430 | 0.000 | 0.1908 | No |
| 28 | STX10 | syntaxin 10 [Source:HGNC Symbol;Acc:HGNC:11428] | 17613 | 0.000 | 0.1859 | No |
| 29 | IGF2-AS | IGF2 antisense RNA [Source:HGNC Symbol;Acc:HGNC:14062] | 20806 | 0.000 | 0.0997 | No |
| 30 | EGR4 | early growth response 4 [Source:HGNC Symbol;Acc:HGNC:3241] | 22162 | 0.000 | 0.0631 | No |
| 31 | IRAG1 | inositol 1,4,5-triphosphate receptor associated 1 [Source:HGNC Symbol;Acc:HGNC:7237] | 26379 | 0.000 | -0.0507 | No |
| 32 | IL17B | interleukin 17B [Source:HGNC Symbol;Acc:HGNC:5982] | 26903 | 0.000 | -0.0648 | No |
| 33 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 27646 | -0.053 | -0.0839 | No |
| 34 | TNNC1 | troponin C1, slow skeletal and cardiac type [Source:HGNC Symbol;Acc:HGNC:11943] | 27872 | -0.086 | -0.0883 | No |
| 35 | ITGB1BP2 | integrin subunit beta 1 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6154] | 27903 | -0.091 | -0.0874 | No |
| 36 | ASB2 | ankyrin repeat and SOCS box containing 2 [Source:HGNC Symbol;Acc:HGNC:16012] | 28283 | -0.147 | -0.0949 | No |
| 37 | KCNMB1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6285] | 28372 | -0.161 | -0.0942 | No |
| 38 | PRUNE2 | prune homolog 2 with BCH domain [Source:HGNC Symbol;Acc:HGNC:25209] | 28485 | -0.176 | -0.0940 | No |
| 39 | TPM1 | tropomyosin 1 [Source:HGNC Symbol;Acc:HGNC:12010] | 29225 | -0.285 | -0.1085 | No |
| 40 | PLCB3 | phospholipase C beta 3 [Source:HGNC Symbol;Acc:HGNC:9056] | 31217 | -0.597 | -0.1510 | No |
| 41 | CNN2 | calponin 2 [Source:HGNC Symbol;Acc:HGNC:2156] | 31237 | -0.600 | -0.1402 | No |
| 42 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 32477 | -0.881 | -0.1571 | No |
| 43 | TAZ | tafazzin [Source:HGNC Symbol;Acc:HGNC:11577] | 32859 | -0.993 | -0.1486 | No |
| 44 | SETD2 | SET domain containing 2, histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:18420] | 33166 | -1.084 | -0.1365 | No |
| 45 | MUS81 | MUS81 structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:29814] | 33682 | -1.261 | -0.1266 | No |
| 46 | TGFB1I1 | transforming growth factor beta 1 induced transcript 1 [Source:HGNC Symbol;Acc:HGNC:11767] | 33793 | -1.298 | -0.1051 | No |
| 47 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 33826 | -1.312 | -0.0812 | No |
| 48 | SLC25A4 | solute carrier family 25 member 4 [Source:HGNC Symbol;Acc:HGNC:10990] | 34396 | -1.525 | -0.0678 | No |
| 49 | DIXDC1 | DIX domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23695] | 34879 | -1.739 | -0.0481 | No |
| 50 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 35774 | -2.347 | -0.0279 | No |
| 51 | VCL | vinculin [Source:HGNC Symbol;Acc:HGNC:12665] | 36657 | -3.365 | 0.0117 | No |
