Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_ESPL1 |
| Enrichment Score (ES) | -0.92618805 |
| Normalized Enrichment Score (NES) | -1.6780874 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.181629E-4 |
| FWER p-Value | 0.004 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 23956 | 0.000 | -0.6465 | No |
| 2 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32753 | -0.958 | -0.8741 | No |
| 3 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34684 | -1.643 | -0.9095 | Yes |
| 4 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35138 | -1.892 | -0.9025 | Yes |
| 5 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35407 | -2.067 | -0.8887 | Yes |
| 6 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35632 | -2.222 | -0.8721 | Yes |
| 7 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35759 | -2.331 | -0.8518 | Yes |
| 8 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35941 | -2.490 | -0.8314 | Yes |
| 9 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35993 | -2.546 | -0.8069 | Yes |
| 10 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36083 | -2.637 | -0.7824 | Yes |
| 11 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36125 | -2.680 | -0.7563 | Yes |
| 12 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36129 | -2.683 | -0.7291 | Yes |
| 13 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36138 | -2.694 | -0.7019 | Yes |
| 14 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36139 | -2.694 | -0.6745 | Yes |
| 15 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36191 | -2.745 | -0.6480 | Yes |
| 16 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36239 | -2.787 | -0.6209 | Yes |
| 17 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36251 | -2.795 | -0.5928 | Yes |
| 18 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36255 | -2.798 | -0.5644 | Yes |
| 19 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36367 | -2.940 | -0.5375 | Yes |
| 20 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 36391 | -2.970 | -0.5079 | Yes |
| 21 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36439 | -3.036 | -0.4783 | Yes |
| 22 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36461 | -3.062 | -0.4477 | Yes |
| 23 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36469 | -3.069 | -0.4167 | Yes |
| 24 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36476 | -3.083 | -0.3855 | Yes |
| 25 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36502 | -3.111 | -0.3546 | Yes |
| 26 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36660 | -3.369 | -0.3245 | Yes |
| 27 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36698 | -3.424 | -0.2907 | Yes |
| 28 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36709 | -3.440 | -0.2560 | Yes |
| 29 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36710 | -3.442 | -0.2210 | Yes |
| 30 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36780 | -3.580 | -0.1864 | Yes |
| 31 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36827 | -3.702 | -0.1500 | Yes |
| 32 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36828 | -3.703 | -0.1124 | Yes |
| 33 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36873 | -3.821 | -0.0747 | Yes |
| 34 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36920 | -3.941 | -0.0359 | Yes |
| 35 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36939 | -3.976 | 0.0041 | Yes |
