Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_PCNA |
| Enrichment Score (ES) | -0.88264143 |
| Normalized Enrichment Score (NES) | -1.7548214 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2428 | 0.770 | -0.0610 | No |
| 2 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 2433 | 0.767 | -0.0566 | No |
| 3 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2574 | 0.721 | -0.0561 | No |
| 4 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26019 | 0.000 | -0.6893 | No |
| 5 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31383 | -0.630 | -0.8305 | No |
| 6 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31663 | -0.682 | -0.8340 | No |
| 7 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 32368 | -0.856 | -0.8479 | No |
| 8 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32418 | -0.869 | -0.8441 | No |
| 9 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32753 | -0.958 | -0.8474 | No |
| 10 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33397 | -1.158 | -0.8580 | No |
| 11 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34312 | -1.491 | -0.8738 | Yes |
| 12 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34381 | -1.518 | -0.8667 | Yes |
| 13 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34684 | -1.643 | -0.8651 | Yes |
| 14 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 34697 | -1.649 | -0.8557 | Yes |
| 15 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34837 | -1.712 | -0.8493 | Yes |
| 16 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35062 | -1.840 | -0.8444 | Yes |
| 17 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35085 | -1.852 | -0.8341 | Yes |
| 18 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35101 | -1.865 | -0.8234 | Yes |
| 19 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35131 | -1.888 | -0.8131 | Yes |
| 20 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35192 | -1.927 | -0.8033 | Yes |
| 21 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 35318 | -2.003 | -0.7948 | Yes |
| 22 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35380 | -2.050 | -0.7843 | Yes |
| 23 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35510 | -2.132 | -0.7752 | Yes |
| 24 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 35638 | -2.227 | -0.7654 | Yes |
| 25 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35759 | -2.331 | -0.7549 | Yes |
| 26 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35776 | -2.350 | -0.7414 | Yes |
| 27 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 35779 | -2.351 | -0.7275 | Yes |
| 28 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35807 | -2.374 | -0.7142 | Yes |
| 29 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35830 | -2.402 | -0.7006 | Yes |
| 30 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35941 | -2.490 | -0.6888 | Yes |
| 31 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35981 | -2.530 | -0.6749 | Yes |
| 32 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35993 | -2.546 | -0.6601 | Yes |
| 33 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36083 | -2.637 | -0.6469 | Yes |
| 34 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36125 | -2.680 | -0.6322 | Yes |
| 35 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36129 | -2.683 | -0.6164 | Yes |
| 36 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36138 | -2.694 | -0.6006 | Yes |
| 37 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36139 | -2.694 | -0.5847 | Yes |
| 38 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36191 | -2.745 | -0.5698 | Yes |
| 39 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36199 | -2.753 | -0.5537 | Yes |
| 40 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36239 | -2.787 | -0.5383 | Yes |
| 41 | PAXIP1 | PAX interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:8624] | 36313 | -2.864 | -0.5233 | Yes |
| 42 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36350 | -2.926 | -0.5069 | Yes |
| 43 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36359 | -2.931 | -0.4898 | Yes |
| 44 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36361 | -2.936 | -0.4725 | Yes |
| 45 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36367 | -2.940 | -0.4552 | Yes |
| 46 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36421 | -3.011 | -0.4388 | Yes |
| 47 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36426 | -3.017 | -0.4211 | Yes |
| 48 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36439 | -3.036 | -0.4034 | Yes |
| 49 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36457 | -3.057 | -0.3858 | Yes |
| 50 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36461 | -3.062 | -0.3677 | Yes |
| 51 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36473 | -3.076 | -0.3498 | Yes |
| 52 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36508 | -3.121 | -0.3323 | Yes |
| 53 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36575 | -3.228 | -0.3150 | Yes |
| 54 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36629 | -3.321 | -0.2967 | Yes |
| 55 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36654 | -3.353 | -0.2775 | Yes |
| 56 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36655 | -3.354 | -0.2577 | Yes |
| 57 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36660 | -3.369 | -0.2378 | Yes |
| 58 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36709 | -3.440 | -0.2188 | Yes |
| 59 | KIF15 | kinesin family member 15 [Source:HGNC Symbol;Acc:HGNC:17273] | 36755 | -3.524 | -0.1991 | Yes |
| 60 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36802 | -3.632 | -0.1789 | Yes |
| 61 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36817 | -3.672 | -0.1575 | Yes |
| 62 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36828 | -3.703 | -0.1359 | Yes |
| 63 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36873 | -3.821 | -0.1145 | Yes |
| 64 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36920 | -3.941 | -0.0924 | Yes |
| 65 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36935 | -3.972 | -0.0692 | Yes |
| 66 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36939 | -3.976 | -0.0458 | Yes |
| 67 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36994 | -4.180 | -0.0225 | Yes |
| 68 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 37006 | -4.236 | 0.0023 | Yes |
