Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_RRM2 |
| Enrichment Score (ES) | -0.91098976 |
| Normalized Enrichment Score (NES) | -1.6797234 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.499792E-4 |
| FWER p-Value | 0.004 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26019 | 0.000 | -0.7022 | No |
| 2 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32418 | -0.869 | -0.8669 | No |
| 3 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32753 | -0.958 | -0.8671 | No |
| 4 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34381 | -1.518 | -0.8970 | Yes |
| 5 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 34439 | -1.540 | -0.8843 | Yes |
| 6 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34684 | -1.643 | -0.8757 | Yes |
| 7 | SMC1A | structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111] | 34943 | -1.772 | -0.8663 | Yes |
| 8 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35062 | -1.840 | -0.8525 | Yes |
| 9 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35380 | -2.050 | -0.8422 | Yes |
| 10 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35632 | -2.222 | -0.8284 | Yes |
| 11 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 35779 | -2.351 | -0.8107 | Yes |
| 12 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35981 | -2.530 | -0.7927 | Yes |
| 13 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35993 | -2.546 | -0.7695 | Yes |
| 14 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36083 | -2.637 | -0.7476 | Yes |
| 15 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36125 | -2.680 | -0.7240 | Yes |
| 16 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36129 | -2.683 | -0.6993 | Yes |
| 17 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36138 | -2.694 | -0.6746 | Yes |
| 18 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36139 | -2.694 | -0.6498 | Yes |
| 19 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36191 | -2.745 | -0.6258 | Yes |
| 20 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36239 | -2.787 | -0.6013 | Yes |
| 21 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36350 | -2.926 | -0.5773 | Yes |
| 22 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36359 | -2.931 | -0.5505 | Yes |
| 23 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36367 | -2.940 | -0.5235 | Yes |
| 24 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36421 | -3.011 | -0.4972 | Yes |
| 25 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36439 | -3.036 | -0.4696 | Yes |
| 26 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36457 | -3.057 | -0.4418 | Yes |
| 27 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36461 | -3.062 | -0.4136 | Yes |
| 28 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36476 | -3.083 | -0.3856 | Yes |
| 29 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36502 | -3.111 | -0.3575 | Yes |
| 30 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36655 | -3.354 | -0.3307 | Yes |
| 31 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36660 | -3.369 | -0.2997 | Yes |
| 32 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36698 | -3.424 | -0.2691 | Yes |
| 33 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36709 | -3.440 | -0.2376 | Yes |
| 34 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36780 | -3.580 | -0.2064 | Yes |
| 35 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36802 | -3.632 | -0.1735 | Yes |
| 36 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36828 | -3.703 | -0.1400 | Yes |
| 37 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36873 | -3.821 | -0.1059 | Yes |
| 38 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36920 | -3.941 | -0.0707 | Yes |
| 39 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36939 | -3.976 | -0.0345 | Yes |
| 40 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36994 | -4.180 | 0.0026 | Yes |
