Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_SMC4L1 |
| Enrichment Score (ES) | -0.818839 |
| Normalized Enrichment Score (NES) | -1.6488672 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.7431362E-4 |
| FWER p-Value | 0.006 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAR1 | GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14264] | 978 | 1.598 | -0.0170 | No |
| 2 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265] | 1582 | 1.153 | -0.0265 | No |
| 3 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2428 | 0.770 | -0.0448 | No |
| 4 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2574 | 0.721 | -0.0445 | No |
| 5 | MRPL35 | mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489] | 2845 | 0.637 | -0.0480 | No |
| 6 | SRSF1 | serine and arginine rich splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:10780] | 2863 | 0.632 | -0.0448 | No |
| 7 | NUP153 | nucleoporin 153 [Source:HGNC Symbol;Acc:HGNC:8062] | 3513 | 0.477 | -0.0595 | No |
| 8 | DKC1 | dyskerin pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:2890] | 3806 | 0.420 | -0.0649 | No |
| 9 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 5094 | 0.162 | -0.0987 | No |
| 10 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 5782 | 0.036 | -0.1171 | No |
| 11 | SERBP1 | SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17860] | 5962 | 0.001 | -0.1219 | No |
| 12 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26019 | 0.000 | -0.6639 | No |
| 13 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 27879 | -0.086 | -0.7136 | No |
| 14 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 29048 | -0.257 | -0.7437 | No |
| 15 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 29854 | -0.377 | -0.7632 | No |
| 16 | COPS3 | COP9 signalosome subunit 3 [Source:HGNC Symbol;Acc:HGNC:2239] | 31382 | -0.630 | -0.8007 | No |
| 17 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31383 | -0.630 | -0.7970 | No |
| 18 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 32189 | -0.808 | -0.8140 | Yes |
| 19 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 32368 | -0.856 | -0.8138 | Yes |
| 20 | HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13729] | 32379 | -0.859 | -0.8090 | Yes |
| 21 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32418 | -0.869 | -0.8049 | Yes |
| 22 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 32525 | -0.892 | -0.8025 | Yes |
| 23 | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit [Source:HGNC Symbol;Acc:HGNC:11465] | 32601 | -0.917 | -0.7992 | Yes |
| 24 | ANP32B | acidic nuclear phosphoprotein 32 family member B [Source:HGNC Symbol;Acc:HGNC:16677] | 32602 | -0.917 | -0.7938 | Yes |
| 25 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32753 | -0.958 | -0.7922 | Yes |
| 26 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33208 | -1.098 | -0.7980 | Yes |
| 27 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33397 | -1.158 | -0.7962 | Yes |
| 28 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 34013 | -1.377 | -0.8047 | Yes |
| 29 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 34095 | -1.401 | -0.7987 | Yes |
| 30 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 34294 | -1.485 | -0.7953 | Yes |
| 31 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34312 | -1.491 | -0.7870 | Yes |
| 32 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34381 | -1.518 | -0.7799 | Yes |
| 33 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34684 | -1.643 | -0.7783 | Yes |
| 34 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34837 | -1.712 | -0.7724 | Yes |
| 35 | EXOSC8 | exosome component 8 [Source:HGNC Symbol;Acc:HGNC:17035] | 34907 | -1.757 | -0.7639 | Yes |
| 36 | USP1 | ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607] | 35006 | -1.806 | -0.7559 | Yes |
| 37 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35062 | -1.840 | -0.7466 | Yes |
| 38 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35085 | -1.852 | -0.7362 | Yes |
| 39 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35101 | -1.865 | -0.7257 | Yes |
| 40 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35131 | -1.888 | -0.7153 | Yes |
| 41 | DEK | DEK proto-oncogene [Source:HGNC Symbol;Acc:HGNC:2768] | 35153 | -1.902 | -0.7047 | Yes |
| 42 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35192 | -1.927 | -0.6944 | Yes |
| 43 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35290 | -1.989 | -0.6853 | Yes |
| 44 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 35318 | -2.003 | -0.6742 | Yes |
| 45 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35380 | -2.050 | -0.6638 | Yes |
| 46 | ZWILCH | zwilch kinetochore protein [Source:HGNC Symbol;Acc:HGNC:25468] | 35412 | -2.072 | -0.6524 | Yes |
| 47 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35510 | -2.132 | -0.6425 | Yes |
| 48 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35759 | -2.331 | -0.6355 | Yes |
| 49 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35776 | -2.350 | -0.6221 | Yes |
| 50 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 35779 | -2.351 | -0.6083 | Yes |
| 51 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35807 | -2.374 | -0.5950 | Yes |
| 52 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35830 | -2.402 | -0.5815 | Yes |
| 53 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35981 | -2.530 | -0.5706 | Yes |
| 54 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35993 | -2.546 | -0.5559 | Yes |
| 55 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36083 | -2.637 | -0.5428 | Yes |
| 56 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36191 | -2.745 | -0.5295 | Yes |
| 57 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36199 | -2.753 | -0.5135 | Yes |
| 58 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36239 | -2.787 | -0.4982 | Yes |
| 59 | FBXO5 | F-box protein 5 [Source:HGNC Symbol;Acc:HGNC:13584] | 36281 | -2.827 | -0.4826 | Yes |
| 60 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36350 | -2.926 | -0.4672 | Yes |
| 61 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36359 | -2.931 | -0.4502 | Yes |
| 62 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36361 | -2.936 | -0.4329 | Yes |
| 63 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36367 | -2.940 | -0.4158 | Yes |
| 64 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36421 | -3.011 | -0.3994 | Yes |
| 65 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36426 | -3.017 | -0.3818 | Yes |
| 66 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36457 | -3.057 | -0.3646 | Yes |
| 67 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36461 | -3.062 | -0.3467 | Yes |
| 68 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36473 | -3.076 | -0.3288 | Yes |
| 69 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36575 | -3.228 | -0.3126 | Yes |
| 70 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36629 | -3.321 | -0.2944 | Yes |
| 71 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36654 | -3.353 | -0.2753 | Yes |
| 72 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36655 | -3.354 | -0.2556 | Yes |
| 73 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36660 | -3.369 | -0.2359 | Yes |
| 74 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36709 | -3.440 | -0.2169 | Yes |
| 75 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 36752 | -3.519 | -0.1973 | Yes |
| 76 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36802 | -3.632 | -0.1772 | Yes |
| 77 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 36812 | -3.660 | -0.1559 | Yes |
| 78 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36817 | -3.672 | -0.1344 | Yes |
| 79 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36828 | -3.703 | -0.1129 | Yes |
| 80 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36920 | -3.941 | -0.0921 | Yes |
| 81 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36935 | -3.972 | -0.0691 | Yes |
| 82 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36953 | -4.019 | -0.0459 | Yes |
| 83 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36994 | -4.180 | -0.0224 | Yes |
| 84 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 37006 | -4.236 | 0.0023 | Yes |
