Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_121 |
| Enrichment Score (ES) | 0.6403584 |
| Normalized Enrichment Score (NES) | 1.6562448 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.067873746 |
| FWER p-Value | 0.407 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 0 | 4.995 | 0.0413 | Yes |
| 2 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.994 | 0.0826 | Yes |
| 3 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 6 | 4.951 | 0.1235 | Yes |
| 4 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 10 | 4.932 | 0.1642 | Yes |
| 5 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 18 | 4.849 | 0.2041 | Yes |
| 6 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 31 | 4.715 | 0.2428 | Yes |
| 7 | OSM | oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506] | 42 | 4.572 | 0.2803 | Yes |
| 8 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 61 | 4.405 | 0.3163 | Yes |
| 9 | VEGFC | vascular endothelial growth factor C [Source:HGNC Symbol;Acc:HGNC:12682] | 63 | 4.382 | 0.3525 | Yes |
| 10 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 67 | 4.339 | 0.3883 | Yes |
| 11 | EDN1 | endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176] | 76 | 4.240 | 0.4232 | Yes |
| 12 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 128 | 3.902 | 0.4541 | Yes |
| 13 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 208 | 3.392 | 0.4800 | Yes |
| 14 | TSPAN3 | tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752] | 326 | 2.820 | 0.5002 | Yes |
| 15 | BCAT1 | branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976] | 400 | 2.610 | 0.5198 | Yes |
| 16 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 595 | 2.141 | 0.5323 | Yes |
| 17 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 681 | 1.981 | 0.5464 | Yes |
| 18 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 761 | 1.874 | 0.5597 | Yes |
| 19 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 795 | 1.824 | 0.5739 | Yes |
| 20 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 802 | 1.811 | 0.5887 | Yes |
| 21 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 1293 | 1.317 | 0.5864 | Yes |
| 22 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 1387 | 1.254 | 0.5942 | Yes |
| 23 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 1390 | 1.252 | 0.6045 | Yes |
| 24 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 1406 | 1.243 | 0.6144 | Yes |
| 25 | FGF7 | fibroblast growth factor 7 [Source:HGNC Symbol;Acc:HGNC:3685] | 1516 | 1.180 | 0.6212 | Yes |
| 26 | HBEGF | heparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059] | 1600 | 1.145 | 0.6285 | Yes |
| 27 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 1765 | 1.052 | 0.6327 | Yes |
| 28 | MXD1 | MAX dimerization protein 1 [Source:HGNC Symbol;Acc:HGNC:6761] | 2353 | 0.796 | 0.6235 | Yes |
| 29 | ZEB1 | zinc finger E-box binding homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11642] | 2379 | 0.787 | 0.6293 | Yes |
| 30 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 2404 | 0.776 | 0.6351 | Yes |
| 31 | MDK | midkine [Source:HGNC Symbol;Acc:HGNC:6972] | 2443 | 0.765 | 0.6404 | Yes |
| 32 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 2890 | 0.626 | 0.6335 | No |
| 33 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 3259 | 0.537 | 0.6280 | No |
| 34 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 3611 | 0.456 | 0.6223 | No |
| 35 | PSPHP1 | phosphoserine phosphatase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9578] | 3779 | 0.426 | 0.6213 | No |
| 36 | KLF6 | Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] | 3835 | 0.413 | 0.6232 | No |
| 37 | EGF | epidermal growth factor [Source:HGNC Symbol;Acc:HGNC:3229] | 4049 | 0.368 | 0.6205 | No |
| 38 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 5139 | 0.162 | 0.5924 | No |
| 39 | CSRP2 | cysteine and glycine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2470] | 5644 | 0.063 | 0.5793 | No |
| 40 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6011 | 0.000 | 0.5694 | No |
| 41 | AREG | amphiregulin [Source:HGNC Symbol;Acc:HGNC:651] | 6943 | 0.000 | 0.5442 | No |
| 42 | PDGFRA | platelet derived growth factor receptor alpha [Source:HGNC Symbol;Acc:HGNC:8803] | 7171 | 0.000 | 0.5381 | No |
| 43 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8492 | 0.000 | 0.5024 | No |
| 44 | GRPR | gastrin releasing peptide receptor [Source:HGNC Symbol;Acc:HGNC:4609] | 9718 | 0.000 | 0.4693 | No |
| 45 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 10678 | 0.000 | 0.4434 | No |
| 46 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 11719 | 0.000 | 0.4152 | No |
| 47 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12287 | 0.000 | 0.3999 | No |
| 48 | IGF2 | insulin like growth factor 2 [Source:HGNC Symbol;Acc:HGNC:5466] | 12303 | 0.000 | 0.3995 | No |
| 49 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12304 | 0.000 | 0.3995 | No |
| 50 | VIP | vasoactive intestinal peptide [Source:HGNC Symbol;Acc:HGNC:12693] | 13007 | 0.000 | 0.3805 | No |
| 51 | VIPR1 | vasoactive intestinal peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:12694] | 13215 | 0.000 | 0.3749 | No |
| 52 | IL15RA | interleukin 15 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5978] | 13996 | 0.000 | 0.3538 | No |
| 53 | TACSTD2 | tumor associated calcium signal transducer 2 [Source:HGNC Symbol;Acc:HGNC:11530] | 14317 | 0.000 | 0.3452 | No |
| 54 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15675 | 0.000 | 0.3085 | No |
| 55 | CD4 | CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678] | 15676 | 0.000 | 0.3085 | No |
| 56 | MST1R | macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381] | 16182 | 0.000 | 0.2949 | No |
| 57 | FGA | fibrinogen alpha chain [Source:HGNC Symbol;Acc:HGNC:3661] | 16613 | 0.000 | 0.2832 | No |
| 58 | FGG | fibrinogen gamma chain [Source:HGNC Symbol;Acc:HGNC:3694] | 16614 | 0.000 | 0.2832 | No |
| 59 | GCG | glucagon [Source:HGNC Symbol;Acc:HGNC:4191] | 16868 | 0.000 | 0.2764 | No |
| 60 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 16998 | 0.000 | 0.2729 | No |
| 61 | IL3 | interleukin 3 [Source:HGNC Symbol;Acc:HGNC:6011] | 17660 | 0.000 | 0.2550 | No |
| 62 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 17767 | 0.000 | 0.2522 | No |
| 63 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 18928 | 0.000 | 0.2208 | No |
| 64 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19380 | 0.000 | 0.2086 | No |
| 65 | PTN | pleiotrophin [Source:HGNC Symbol;Acc:HGNC:9630] | 20053 | 0.000 | 0.1905 | No |
| 66 | EDNRA | endothelin receptor type A [Source:HGNC Symbol;Acc:HGNC:3179] | 21783 | 0.000 | 0.1437 | No |
| 67 | EGR4 | early growth response 4 [Source:HGNC Symbol;Acc:HGNC:3241] | 22162 | 0.000 | 0.1335 | No |
| 68 | CCN1 | cellular communication network factor 1 [Source:HGNC Symbol;Acc:HGNC:2654] | 22865 | 0.000 | 0.1145 | No |
| 69 | SLAMF1 | signaling lymphocytic activation molecule family member 1 [Source:HGNC Symbol;Acc:HGNC:10903] | 22899 | 0.000 | 0.1136 | No |
| 70 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 23018 | 0.000 | 0.1104 | No |
| 71 | CD8A | CD8a molecule [Source:HGNC Symbol;Acc:HGNC:1706] | 23019 | 0.000 | 0.1104 | No |
| 72 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24394 | 0.000 | 0.0733 | No |
| 73 | FGF4 | fibroblast growth factor 4 [Source:HGNC Symbol;Acc:HGNC:3682] | 25251 | 0.000 | 0.0502 | No |
| 74 | REG1B | regenerating family member 1 beta [Source:HGNC Symbol;Acc:HGNC:9952] | 26246 | 0.000 | 0.0233 | No |
| 75 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 27601 | -0.044 | -0.0129 | No |
| 76 | ERG | ETS transcription factor ERG [Source:HGNC Symbol;Acc:HGNC:3446] | 29144 | -0.271 | -0.0524 | No |
| 77 | EPHB4 | EPH receptor B4 [Source:HGNC Symbol;Acc:HGNC:3395] | 29556 | -0.334 | -0.0607 | No |
| 78 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 29680 | -0.351 | -0.0612 | No |
| 79 | GRN | granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601] | 30681 | -0.507 | -0.0840 | No |
| 80 | IGF1 | insulin like growth factor 1 [Source:HGNC Symbol;Acc:HGNC:5464] | 31515 | -0.655 | -0.1011 | No |
| 81 | IL6R | interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019] | 31639 | -0.678 | -0.0988 | No |
| 82 | FGB | fibrinogen beta chain [Source:HGNC Symbol;Acc:HGNC:3662] | 31659 | -0.681 | -0.0937 | No |
| 83 | AKR1C3 | aldo-keto reductase family 1 member C3 [Source:HGNC Symbol;Acc:HGNC:386] | 32315 | -0.842 | -0.1044 | No |
| 84 | GAS6 | growth arrest specific 6 [Source:HGNC Symbol;Acc:HGNC:4168] | 32784 | -0.970 | -0.1091 | No |
| 85 | TGFB3 | transforming growth factor beta 3 [Source:HGNC Symbol;Acc:HGNC:11769] | 33002 | -1.038 | -0.1064 | No |
| 86 | CRIP1 | cysteine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:2360] | 33094 | -1.061 | -0.1000 | No |
| 87 | SFN | stratifin [Source:HGNC Symbol;Acc:HGNC:10773] | 33098 | -1.062 | -0.0913 | No |
| 88 | MAPRE2 | microtubule associated protein RP/EB family member 2 [Source:HGNC Symbol;Acc:HGNC:6891] | 33487 | -1.186 | -0.0920 | No |
| 89 | RUNX3 | RUNX family transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473] | 33606 | -1.233 | -0.0850 | No |
| 90 | CDK5R1 | cyclin dependent kinase 5 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:1775] | 33727 | -1.274 | -0.0777 | No |
| 91 | INSIG1 | insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083] | 34221 | -1.457 | -0.0790 | No |
| 92 | CREG1 | cellular repressor of E1A stimulated genes 1 [Source:HGNC Symbol;Acc:HGNC:2351] | 34250 | -1.466 | -0.0676 | No |
| 93 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 34448 | -1.544 | -0.0602 | No |
| 94 | LRP1 | LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692] | 35450 | -2.098 | -0.0699 | No |
| 95 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 35623 | -2.214 | -0.0562 | No |
| 96 | EMP1 | epithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333] | 35786 | -2.355 | -0.0411 | No |
| 97 | EPS8 | epidermal growth factor receptor pathway substrate 8 [Source:HGNC Symbol;Acc:HGNC:3420] | 36318 | -2.877 | -0.0317 | No |
| 98 | BCAR1 | BCAR1 scaffold protein, Cas family member [Source:HGNC Symbol;Acc:HGNC:971] | 36524 | -3.153 | -0.0111 | No |
| 99 | ZFP36L2 | ZFP36 ring finger protein like 2 [Source:HGNC Symbol;Acc:HGNC:1108] | 36549 | -3.191 | 0.0146 | No |
