Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_208 |
| Enrichment Score (ES) | 0.600733 |
| Normalized Enrichment Score (NES) | 1.5856419 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.123836055 |
| FWER p-Value | 0.679 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 6 | 4.951 | 0.0384 | Yes |
| 2 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 17 | 4.863 | 0.0761 | Yes |
| 3 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 19 | 4.836 | 0.1137 | Yes |
| 4 | CFB | complement factor B [Source:HGNC Symbol;Acc:HGNC:1037] | 24 | 4.783 | 0.1509 | Yes |
| 5 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 29 | 4.760 | 0.1879 | Yes |
| 6 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 47 | 4.510 | 0.2226 | Yes |
| 7 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 51 | 4.480 | 0.2574 | Yes |
| 8 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 94 | 4.083 | 0.2881 | Yes |
| 9 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 96 | 4.071 | 0.3198 | Yes |
| 10 | PELI1 | pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827] | 119 | 3.934 | 0.3499 | Yes |
| 11 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 154 | 3.699 | 0.3778 | Yes |
| 12 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 168 | 3.624 | 0.4057 | Yes |
| 13 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 208 | 3.392 | 0.4310 | Yes |
| 14 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 210 | 3.374 | 0.4573 | Yes |
| 15 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 227 | 3.279 | 0.4824 | Yes |
| 16 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 251 | 3.171 | 0.5065 | Yes |
| 17 | NLRC5 | NLR family CARD domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29933] | 290 | 2.979 | 0.5287 | Yes |
| 18 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 627 | 2.101 | 0.5360 | Yes |
| 19 | IFITM2 | interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413] | 629 | 2.094 | 0.5523 | Yes |
| 20 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 891 | 1.701 | 0.5585 | Yes |
| 21 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 941 | 1.639 | 0.5699 | Yes |
| 22 | TXLNGY | taxilin gamma pseudogene, Y-linked [Source:HGNC Symbol;Acc:HGNC:18473] | 1059 | 1.514 | 0.5786 | Yes |
| 23 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 1332 | 1.295 | 0.5813 | Yes |
| 24 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 1339 | 1.287 | 0.5912 | Yes |
| 25 | FOXP1 | forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823] | 1469 | 1.207 | 0.5971 | Yes |
| 26 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1808 | 1.029 | 0.5960 | Yes |
| 27 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 1918 | 0.987 | 0.6007 | Yes |
| 28 | P2RY10 | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] | 2191 | 0.860 | 0.6001 | No |
| 29 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 2404 | 0.776 | 0.6004 | No |
| 30 | CCDC186 | coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349] | 2709 | 0.674 | 0.5974 | No |
| 31 | PPP1R16B | protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] | 2816 | 0.645 | 0.5996 | No |
| 32 | CPVL | carboxypeptidase vitellogenic like [Source:HGNC Symbol;Acc:HGNC:14399] | 3230 | 0.545 | 0.5926 | No |
| 33 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 3415 | 0.501 | 0.5916 | No |
| 34 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 3430 | 0.500 | 0.5951 | No |
| 35 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638] | 3715 | 0.436 | 0.5908 | No |
| 36 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 3728 | 0.434 | 0.5939 | No |
| 37 | KLF6 | Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] | 3835 | 0.413 | 0.5942 | No |
| 38 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 3868 | 0.408 | 0.5965 | No |
| 39 | CNRIP1 | cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546] | 5071 | 0.166 | 0.5653 | No |
| 40 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 5139 | 0.162 | 0.5648 | No |
| 41 | POLR3B | RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] | 5216 | 0.148 | 0.5639 | No |
| 42 | MCU | mitochondrial calcium uniporter [Source:HGNC Symbol;Acc:HGNC:23526] | 5227 | 0.145 | 0.5647 | No |
| 43 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6033 | 0.000 | 0.5430 | No |
| 44 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 6475 | 0.000 | 0.5310 | No |
| 45 | SELP | selectin P [Source:HGNC Symbol;Acc:HGNC:10721] | 6806 | 0.000 | 0.5221 | No |
| 46 | STAG3 | stromal antigen 3 [Source:HGNC Symbol;Acc:HGNC:11356] | 7482 | 0.000 | 0.5038 | No |
| 47 | CD200 | CD200 molecule [Source:HGNC Symbol;Acc:HGNC:7203] | 7786 | 0.000 | 0.4956 | No |
| 48 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 8713 | 0.000 | 0.4706 | No |
| 49 | KCNQ5 | potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299] | 9572 | 0.000 | 0.4474 | No |
| 50 | ADAM19 | ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197] | 9640 | 0.000 | 0.4456 | No |
| 51 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 9645 | 0.000 | 0.4455 | No |
| 52 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 9787 | 0.000 | 0.4417 | No |
| 53 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 10274 | 0.000 | 0.4285 | No |
| 54 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 10788 | 0.000 | 0.4146 | No |
| 55 | GZMA | granzyme A [Source:HGNC Symbol;Acc:HGNC:4708] | 11885 | 0.000 | 0.3850 | No |
| 56 | NEK11 | NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593] | 11953 | 0.000 | 0.3832 | No |
| 57 | UNC79 | unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966] | 12270 | 0.000 | 0.3746 | No |
| 58 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12274 | 0.000 | 0.3745 | No |
| 59 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12340 | 0.000 | 0.3728 | No |
| 60 | LILRB1 | leukocyte immunoglobulin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6605] | 13280 | 0.000 | 0.3474 | No |
| 61 | TPTE2 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299] | 13695 | 0.000 | 0.3362 | No |
| 62 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13720 | 0.000 | 0.3355 | No |
| 63 | PNMA8A | PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578] | 14466 | 0.000 | 0.3154 | No |
| 64 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15551 | 0.000 | 0.2861 | No |
| 65 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15675 | 0.000 | 0.2827 | No |
| 66 | XCL1 | X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645] | 15790 | 0.000 | 0.2796 | No |
| 67 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16110 | 0.000 | 0.2710 | No |
| 68 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16139 | 0.000 | 0.2703 | No |
| 69 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16438 | 0.000 | 0.2622 | No |
| 70 | IL3RA | interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012] | 16448 | 0.000 | 0.2620 | No |
| 71 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527] | 17097 | 0.000 | 0.2444 | No |
| 72 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17732 | 0.000 | 0.2273 | No |
| 73 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18324 | 0.000 | 0.2113 | No |
| 74 | IGLJ3 | immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865] | 18343 | 0.000 | 0.2108 | No |
| 75 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938] | 18780 | 0.000 | 0.1990 | No |
| 76 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940] | 18800 | 0.000 | 0.1985 | No |
| 77 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18806 | 0.000 | 0.1984 | No |
| 78 | MAL | mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817] | 18825 | 0.000 | 0.1979 | No |
| 79 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19368 | 0.000 | 0.1832 | No |
| 80 | TCF7 | transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639] | 19734 | 0.000 | 0.1733 | No |
| 81 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 20577 | 0.000 | 0.1506 | No |
| 82 | UNC5D | unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634] | 20778 | 0.000 | 0.1452 | No |
| 83 | CMKLR1 | chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121] | 22301 | 0.000 | 0.1040 | No |
| 84 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22346 | 0.000 | 0.1028 | No |
| 85 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22828 | 0.000 | 0.0898 | No |
| 86 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 22921 | 0.000 | 0.0873 | No |
| 87 | CD48 | CD48 molecule [Source:HGNC Symbol;Acc:HGNC:1683] | 22950 | 0.000 | 0.0865 | No |
| 88 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 23018 | 0.000 | 0.0847 | No |
| 89 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 23094 | 0.000 | 0.0827 | No |
| 90 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 23246 | 0.000 | 0.0786 | No |
| 91 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 23370 | 0.000 | 0.0753 | No |
| 92 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 23524 | 0.000 | 0.0711 | No |
| 93 | HBA2 | hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824] | 24949 | 0.000 | 0.0326 | No |
| 94 | CD79A | CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698] | 25390 | 0.000 | 0.0207 | No |
| 95 | STK31 | serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407] | 25671 | 0.000 | 0.0131 | No |
| 96 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 27941 | -0.095 | -0.0475 | No |
| 97 | AXIN1 | axin 1 [Source:HGNC Symbol;Acc:HGNC:903] | 28591 | -0.187 | -0.0636 | No |
| 98 | USP30 | ubiquitin specific peptidase 30 [Source:HGNC Symbol;Acc:HGNC:20065] | 28736 | -0.210 | -0.0658 | No |
| 99 | CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene [Source:HGNC Symbol;Acc:HGNC:2098] | 29209 | -0.282 | -0.0764 | No |
| 100 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944] | 29389 | -0.310 | -0.0788 | No |
| 101 | HLA-DMB | major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935] | 29547 | -0.333 | -0.0805 | No |
| 102 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 29779 | -0.366 | -0.0839 | No |
| 103 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 30535 | -0.483 | -0.1005 | No |
| 104 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 30719 | -0.514 | -0.1015 | No |
| 105 | ZNF292 | zinc finger protein 292 [Source:HGNC Symbol;Acc:HGNC:18410] | 30947 | -0.551 | -0.1033 | No |
| 106 | KCNA3 | potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221] | 31111 | -0.578 | -0.1032 | No |
| 107 | KIAA0753 | KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110] | 31682 | -0.686 | -0.1133 | No |
| 108 | HLA-DMA | major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934] | 31797 | -0.706 | -0.1109 | No |
| 109 | BANK1 | B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233] | 32066 | -0.771 | -0.1121 | No |
| 110 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 32480 | -0.882 | -0.1164 | No |
| 111 | TTC30A | tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853] | 32699 | -0.946 | -0.1150 | No |
| 112 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 32794 | -0.972 | -0.1099 | No |
| 113 | HVCN1 | hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240] | 34922 | -1.763 | -0.1537 | No |
| 114 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 35275 | -1.977 | -0.1478 | No |
| 115 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 35440 | -2.088 | -0.1360 | No |
| 116 | S1PR1 | sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165] | 35609 | -2.201 | -0.1234 | No |
| 117 | SLC40A1 | solute carrier family 40 member 1 [Source:HGNC Symbol;Acc:HGNC:10909] | 36023 | -2.574 | -0.1145 | No |
| 118 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36193 | -2.746 | -0.0977 | No |
| 119 | GMCL1 | germ cell-less 1, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:23843] | 36227 | -2.779 | -0.0769 | No |
| 120 | ABTB1 | ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275] | 36304 | -2.850 | -0.0567 | No |
| 121 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36442 | -3.043 | -0.0367 | No |
| 122 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36606 | -3.271 | -0.0156 | No |
| 123 | IGHM | immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541] | 36821 | -3.684 | 0.0073 | No |
