Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_345 |
| Enrichment Score (ES) | 0.6706716 |
| Normalized Enrichment Score (NES) | 1.7489613 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.037830222 |
| FWER p-Value | 0.125 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 6 | 4.951 | 0.0356 | Yes |
| 2 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 15 | 4.872 | 0.0706 | Yes |
| 3 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 17 | 4.863 | 0.1057 | Yes |
| 4 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 19 | 4.836 | 0.1406 | Yes |
| 5 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 20 | 4.828 | 0.1755 | Yes |
| 6 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 47 | 4.510 | 0.2074 | Yes |
| 7 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 51 | 4.480 | 0.2397 | Yes |
| 8 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 94 | 4.083 | 0.2680 | Yes |
| 9 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 96 | 4.071 | 0.2974 | Yes |
| 10 | PELI1 | pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827] | 119 | 3.934 | 0.3252 | Yes |
| 11 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 145 | 3.779 | 0.3519 | Yes |
| 12 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 154 | 3.699 | 0.3784 | Yes |
| 13 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 168 | 3.624 | 0.4042 | Yes |
| 14 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 172 | 3.617 | 0.4303 | Yes |
| 15 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 174 | 3.614 | 0.4563 | Yes |
| 16 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 210 | 3.374 | 0.4798 | Yes |
| 17 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 220 | 3.316 | 0.5035 | Yes |
| 18 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 227 | 3.279 | 0.5270 | Yes |
| 19 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 251 | 3.171 | 0.5493 | Yes |
| 20 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 269 | 3.083 | 0.5711 | Yes |
| 21 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 580 | 2.164 | 0.5784 | Yes |
| 22 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 627 | 2.101 | 0.5923 | Yes |
| 23 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 891 | 1.701 | 0.5975 | Yes |
| 24 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 941 | 1.639 | 0.6080 | Yes |
| 25 | TXLNGY | taxilin gamma pseudogene, Y-linked [Source:HGNC Symbol;Acc:HGNC:18473] | 1059 | 1.514 | 0.6158 | Yes |
| 26 | BLNK | B cell linker [Source:HGNC Symbol;Acc:HGNC:14211] | 1202 | 1.389 | 0.6220 | Yes |
| 27 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 1332 | 1.295 | 0.6278 | Yes |
| 28 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 1339 | 1.287 | 0.6370 | Yes |
| 29 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 1464 | 1.209 | 0.6424 | Yes |
| 30 | FOXP1 | forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823] | 1469 | 1.207 | 0.6510 | Yes |
| 31 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 1772 | 1.050 | 0.6504 | Yes |
| 32 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1808 | 1.029 | 0.6569 | Yes |
| 33 | UNKL | unk like zinc finger [Source:HGNC Symbol;Acc:HGNC:14184] | 1834 | 1.022 | 0.6636 | Yes |
| 34 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 1918 | 0.987 | 0.6685 | Yes |
| 35 | P2RY10 | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] | 2191 | 0.860 | 0.6673 | Yes |
| 36 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 2404 | 0.776 | 0.6672 | Yes |
| 37 | ZNF436 | zinc finger protein 436 [Source:HGNC Symbol;Acc:HGNC:20814] | 2649 | 0.693 | 0.6656 | Yes |
| 38 | CCDC186 | coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349] | 2709 | 0.674 | 0.6689 | Yes |
| 39 | PPP1R16B | protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] | 2816 | 0.645 | 0.6707 | Yes |
| 40 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 3415 | 0.501 | 0.6581 | No |
| 41 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 3430 | 0.500 | 0.6614 | No |
| 42 | SPIB | Spi-B transcription factor [Source:HGNC Symbol;Acc:HGNC:11242] | 3702 | 0.438 | 0.6572 | No |
| 43 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638] | 3715 | 0.436 | 0.6600 | No |
| 44 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 3728 | 0.434 | 0.6628 | No |
| 45 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 3868 | 0.408 | 0.6620 | No |
| 46 | MECP2 | methyl-CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990] | 4858 | 0.208 | 0.6368 | No |
| 47 | CNRIP1 | cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546] | 5071 | 0.166 | 0.6322 | No |
| 48 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 5139 | 0.162 | 0.6316 | No |
| 49 | UNC13B | unc-13 homolog B [Source:HGNC Symbol;Acc:HGNC:12566] | 5167 | 0.158 | 0.6320 | No |
| 50 | POLR3B | RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] | 5216 | 0.148 | 0.6318 | No |
| 51 | FCRL2 | Fc receptor like 2 [Source:HGNC Symbol;Acc:HGNC:14875] | 5740 | 0.046 | 0.6179 | No |
| 52 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6033 | 0.000 | 0.6100 | No |
| 53 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 6475 | 0.000 | 0.5981 | No |
| 54 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 6807 | 0.000 | 0.5892 | No |
| 55 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 8713 | 0.000 | 0.5376 | No |
| 56 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9381 | 0.000 | 0.5196 | No |
| 57 | KCNQ5 | potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299] | 9572 | 0.000 | 0.5144 | No |
| 58 | ADAM19 | ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197] | 9640 | 0.000 | 0.5126 | No |
| 59 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 9645 | 0.000 | 0.5125 | No |
| 60 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 9787 | 0.000 | 0.5087 | No |
| 61 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 10274 | 0.000 | 0.4956 | No |
| 62 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 10788 | 0.000 | 0.4817 | No |
| 63 | NEK11 | NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593] | 11953 | 0.000 | 0.4502 | No |
| 64 | UNC79 | unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966] | 12270 | 0.000 | 0.4416 | No |
| 65 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12274 | 0.000 | 0.4416 | No |
| 66 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12304 | 0.000 | 0.4408 | No |
| 67 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12340 | 0.000 | 0.4398 | No |
| 68 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 12913 | 0.000 | 0.4244 | No |
| 69 | TPTE2 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299] | 13695 | 0.000 | 0.4032 | No |
| 70 | PNMA8A | PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578] | 14466 | 0.000 | 0.3824 | No |
| 71 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15551 | 0.000 | 0.3531 | No |
| 72 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15675 | 0.000 | 0.3497 | No |
| 73 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16110 | 0.000 | 0.3380 | No |
| 74 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16139 | 0.000 | 0.3372 | No |
| 75 | MST1L | macrophage stimulating 1 like [Source:HGNC Symbol;Acc:HGNC:7390] | 16183 | 0.000 | 0.3361 | No |
| 76 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16438 | 0.000 | 0.3292 | No |
| 77 | IL3RA | interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012] | 16448 | 0.000 | 0.3290 | No |
| 78 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527] | 17097 | 0.000 | 0.3114 | No |
| 79 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17732 | 0.000 | 0.2943 | No |
| 80 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18324 | 0.000 | 0.2783 | No |
| 81 | IGLJ3 | immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865] | 18343 | 0.000 | 0.2778 | No |
| 82 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18373 | 0.000 | 0.2770 | No |
| 83 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938] | 18780 | 0.000 | 0.2660 | No |
| 84 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940] | 18800 | 0.000 | 0.2655 | No |
| 85 | MAL | mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817] | 18825 | 0.000 | 0.2649 | No |
| 86 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19368 | 0.000 | 0.2502 | No |
| 87 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 20577 | 0.000 | 0.2175 | No |
| 88 | UNC5D | unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634] | 20778 | 0.000 | 0.2121 | No |
| 89 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22346 | 0.000 | 0.1697 | No |
| 90 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22828 | 0.000 | 0.1567 | No |
| 91 | CD19 | CD19 molecule [Source:HGNC Symbol;Acc:HGNC:1633] | 22893 | 0.000 | 0.1550 | No |
| 92 | CD27 | CD27 molecule [Source:HGNC Symbol;Acc:HGNC:11922] | 22910 | 0.000 | 0.1546 | No |
| 93 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 22921 | 0.000 | 0.1543 | No |
| 94 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 23246 | 0.000 | 0.1455 | No |
| 95 | UCP1 | uncoupling protein 1 [Source:HGNC Symbol;Acc:HGNC:12517] | 23281 | 0.000 | 0.1446 | No |
| 96 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 23370 | 0.000 | 0.1422 | No |
| 97 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 23524 | 0.000 | 0.1381 | No |
| 98 | ADGRE2 | adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337] | 24241 | 0.000 | 0.1187 | No |
| 99 | HBA2 | hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824] | 24949 | 0.000 | 0.0996 | No |
| 100 | CD79B | CD79b molecule [Source:HGNC Symbol;Acc:HGNC:1699] | 25389 | 0.000 | 0.0877 | No |
| 101 | CD79A | CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698] | 25390 | 0.000 | 0.0877 | No |
| 102 | STK31 | serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407] | 25671 | 0.000 | 0.0801 | No |
| 103 | SLC22A23 | solute carrier family 22 member 23 [Source:HGNC Symbol;Acc:HGNC:21106] | 26599 | 0.000 | 0.0551 | No |
| 104 | AXIN1 | axin 1 [Source:HGNC Symbol;Acc:HGNC:903] | 28591 | -0.187 | 0.0026 | No |
| 105 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944] | 29389 | -0.310 | -0.0168 | No |
| 106 | HLA-DMB | major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935] | 29547 | -0.333 | -0.0186 | No |
| 107 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 29779 | -0.366 | -0.0222 | No |
| 108 | FCRLA | Fc receptor like A [Source:HGNC Symbol;Acc:HGNC:18504] | 30259 | -0.439 | -0.0320 | No |
| 109 | RUBCNL | rubicon like autophagy enhancer [Source:HGNC Symbol;Acc:HGNC:20420] | 30379 | -0.458 | -0.0319 | No |
| 110 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 30535 | -0.483 | -0.0326 | No |
| 111 | CD37 | CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666] | 31357 | -0.624 | -0.0503 | No |
| 112 | KIAA0753 | KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110] | 31682 | -0.686 | -0.0541 | No |
| 113 | HLA-DMA | major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934] | 31797 | -0.706 | -0.0521 | No |
| 114 | BANK1 | B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233] | 32066 | -0.771 | -0.0538 | No |
| 115 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 32480 | -0.882 | -0.0586 | No |
| 116 | TTC30A | tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853] | 32699 | -0.946 | -0.0577 | No |
| 117 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 32733 | -0.955 | -0.0517 | No |
| 118 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 32794 | -0.972 | -0.0463 | No |
| 119 | HVCN1 | hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240] | 34922 | -1.763 | -0.0911 | No |
| 120 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 35275 | -1.977 | -0.0863 | No |
| 121 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 35440 | -2.088 | -0.0756 | No |
| 122 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36193 | -2.746 | -0.0761 | No |
| 123 | ABTB1 | ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275] | 36304 | -2.850 | -0.0585 | No |
| 124 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36606 | -3.271 | -0.0430 | No |
| 125 | IGHM | immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541] | 36821 | -3.684 | -0.0222 | No |
| 126 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813] | 36963 | -4.078 | 0.0034 | No |
