Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_76 |
| Enrichment Score (ES) | 0.79803276 |
| Normalized Enrichment Score (NES) | 1.9905052 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.994 | 0.0543 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 4 | 4.965 | 0.1082 | Yes |
| 3 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 10 | 4.932 | 0.1617 | Yes |
| 4 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 26 | 4.768 | 0.2131 | Yes |
| 5 | TLR3 | toll like receptor 3 [Source:HGNC Symbol;Acc:HGNC:11849] | 62 | 4.382 | 0.2598 | Yes |
| 6 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 73 | 4.268 | 0.3059 | Yes |
| 7 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 130 | 3.895 | 0.3467 | Yes |
| 8 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 234 | 3.248 | 0.3792 | Yes |
| 9 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 248 | 3.174 | 0.4134 | Yes |
| 10 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 251 | 3.171 | 0.4478 | Yes |
| 11 | FPR2 | formyl peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:3827] | 368 | 2.715 | 0.4742 | Yes |
| 12 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 425 | 2.542 | 0.5003 | Yes |
| 13 | CXCL14 | C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640] | 461 | 2.452 | 0.5260 | Yes |
| 14 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 486 | 2.398 | 0.5514 | Yes |
| 15 | TLR1 | toll like receptor 1 [Source:HGNC Symbol;Acc:HGNC:11847] | 493 | 2.387 | 0.5772 | Yes |
| 16 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 523 | 2.298 | 0.6014 | Yes |
| 17 | TIRAP | TIR domain containing adaptor protein [Source:HGNC Symbol;Acc:HGNC:17192] | 544 | 2.236 | 0.6251 | Yes |
| 18 | ADORA2A | adenosine A2a receptor [Source:HGNC Symbol;Acc:HGNC:263] | 562 | 2.203 | 0.6486 | Yes |
| 19 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 727 | 1.931 | 0.6652 | Yes |
| 20 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 776 | 1.858 | 0.6841 | Yes |
| 21 | AOAH | acyloxyacyl hydrolase [Source:HGNC Symbol;Acc:HGNC:548] | 800 | 1.812 | 0.7032 | Yes |
| 22 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 802 | 1.811 | 0.7228 | Yes |
| 23 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 850 | 1.758 | 0.7407 | Yes |
| 24 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 858 | 1.747 | 0.7595 | Yes |
| 25 | ANXA1 | annexin A1 [Source:HGNC Symbol;Acc:HGNC:533] | 1311 | 1.309 | 0.7615 | Yes |
| 26 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 1390 | 1.252 | 0.7730 | Yes |
| 27 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 1539 | 1.177 | 0.7818 | Yes |
| 28 | CYBB | cytochrome b-245 beta chain [Source:HGNC Symbol;Acc:HGNC:2578] | 1624 | 1.131 | 0.7918 | Yes |
| 29 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1808 | 1.029 | 0.7980 | Yes |
| 30 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 3112 | 0.574 | 0.7691 | No |
| 31 | AOC3 | amine oxidase copper containing 3 [Source:HGNC Symbol;Acc:HGNC:550] | 4086 | 0.361 | 0.7467 | No |
| 32 | ABCF1 | ATP binding cassette subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:70] | 4615 | 0.252 | 0.7352 | No |
| 33 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 4688 | 0.239 | 0.7358 | No |
| 34 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 5174 | 0.156 | 0.7244 | No |
| 35 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 5331 | 0.124 | 0.7216 | No |
| 36 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796] | 5964 | 0.001 | 0.7045 | No |
| 37 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6012 | 0.000 | 0.7032 | No |
| 38 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6013 | 0.000 | 0.7032 | No |
| 39 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6032 | 0.000 | 0.7027 | No |
| 40 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6033 | 0.000 | 0.7027 | No |
| 41 | CCL17 | C-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:10615] | 6035 | 0.000 | 0.7027 | No |
| 42 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6042 | 0.000 | 0.7025 | No |
| 43 | CCL21 | C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620] | 6044 | 0.000 | 0.7025 | No |
| 44 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6046 | 0.000 | 0.7025 | No |
| 45 | AOX1 | aldehyde oxidase 1 [Source:HGNC Symbol;Acc:HGNC:553] | 6237 | 0.000 | 0.6974 | No |
| 46 | S100A9 | S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499] | 8188 | 0.000 | 0.6447 | No |
| 47 | LY75 | lymphocyte antigen 75 [Source:HGNC Symbol;Acc:HGNC:6729] | 8847 | 0.000 | 0.6269 | No |
| 48 | LY86 | lymphocyte antigen 86 [Source:HGNC Symbol;Acc:HGNC:16837] | 8874 | 0.000 | 0.6262 | No |
| 49 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10448 | 0.000 | 0.5837 | No |
| 50 | S100A12 | S100 calcium binding protein A12 [Source:HGNC Symbol;Acc:HGNC:10489] | 11409 | 0.000 | 0.5577 | No |
| 51 | PTX3 | pentraxin 3 [Source:HGNC Symbol;Acc:HGNC:9692] | 12057 | 0.000 | 0.5403 | No |
| 52 | C4B | complement C4B (Chido blood group) [Source:HGNC Symbol;Acc:HGNC:1324] | 15556 | 0.000 | 0.4457 | No |
| 53 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15821 | 0.000 | 0.4386 | No |
| 54 | C5 | complement C5 [Source:HGNC Symbol;Acc:HGNC:1331] | 16029 | 0.000 | 0.4330 | No |
| 55 | FN1 | fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778] | 16655 | 0.000 | 0.4161 | No |
| 56 | ADORA1 | adenosine A1 receptor [Source:HGNC Symbol;Acc:HGNC:262] | 16695 | 0.000 | 0.4151 | No |
| 57 | MGLL | monoglyceride lipase [Source:HGNC Symbol;Acc:HGNC:17038] | 17085 | 0.000 | 0.4046 | No |
| 58 | IL9 | interleukin 9 [Source:HGNC Symbol;Acc:HGNC:6029] | 17663 | 0.000 | 0.3890 | No |
| 59 | BDKRB2 | bradykinin receptor B2 [Source:HGNC Symbol;Acc:HGNC:1030] | 17900 | 0.000 | 0.3826 | No |
| 60 | ORM1 | orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498] | 18568 | 0.000 | 0.3646 | No |
| 61 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18806 | 0.000 | 0.3582 | No |
| 62 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 18847 | 0.000 | 0.3571 | No |
| 63 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 19249 | 0.000 | 0.3463 | No |
| 64 | CXCR2 | C-X-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:6027] | 19289 | 0.000 | 0.3452 | No |
| 65 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19366 | 0.000 | 0.3432 | No |
| 66 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19368 | 0.000 | 0.3431 | No |
| 67 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19371 | 0.000 | 0.3431 | No |
| 68 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19380 | 0.000 | 0.3429 | No |
| 69 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19384 | 0.000 | 0.3428 | No |
| 70 | PLA2G7 | phospholipase A2 group VII [Source:HGNC Symbol;Acc:HGNC:9040] | 22004 | 0.000 | 0.2720 | No |
| 71 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22826 | 0.000 | 0.2498 | No |
| 72 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22828 | 0.000 | 0.2498 | No |
| 73 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22836 | 0.000 | 0.2496 | No |
| 74 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 28095 | -0.119 | 0.1088 | No |
| 75 | AGER | advanced glycosylation end-product specific receptor [Source:HGNC Symbol;Acc:HGNC:320] | 29540 | -0.332 | 0.0734 | No |
| 76 | NFATC4 | nuclear factor of activated T cells 4 [Source:HGNC Symbol;Acc:HGNC:7778] | 30370 | -0.456 | 0.0560 | No |
| 77 | AIF1 | allograft inflammatory factor 1 [Source:HGNC Symbol;Acc:HGNC:352] | 31603 | -0.671 | 0.0300 | No |
| 78 | CXCR4 | C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561] | 33282 | -1.123 | -0.0031 | No |
| 79 | LYZ | lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] | 33792 | -1.297 | -0.0028 | No |
| 80 | ALOX5AP | arachidonate 5-lipoxygenase activating protein [Source:HGNC Symbol;Acc:HGNC:436] | 36877 | -3.832 | -0.0445 | No |
| 81 | ALOX5 | arachidonate 5-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:435] | 37066 | -4.618 | 0.0006 | No |
