Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOMF_POSTSYNAPTIC_NEUROTRANSMITTER_RECEPTOR_ACTIVITY |
| Enrichment Score (ES) | -0.81709445 |
| Normalized Enrichment Score (NES) | -1.5839728 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07764423 |
| FWER p-Value | 0.606 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GRIA1 | glutamate ionotropic receptor AMPA type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4571] | 8859 | 0.000 | -0.2392 | No |
| 2 | GRIA3 | glutamate ionotropic receptor AMPA type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4573] | 8870 | 0.000 | -0.2395 | No |
| 3 | GRID2 | glutamate ionotropic receptor delta type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4576] | 8888 | 0.000 | -0.2400 | No |
| 4 | GRID1 | glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575] | 8890 | 0.000 | -0.2400 | No |
| 5 | GRIK3 | glutamate ionotropic receptor kainate type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4581] | 8980 | 0.000 | -0.2424 | No |
| 6 | GRIK4 | glutamate ionotropic receptor kainate type subunit 4 [Source:HGNC Symbol;Acc:HGNC:4582] | 8981 | 0.000 | -0.2424 | No |
| 7 | GRIK1 | glutamate ionotropic receptor kainate type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4579] | 8982 | 0.000 | -0.2424 | No |
| 8 | GRIK2 | glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580] | 8983 | 0.000 | -0.2424 | No |
| 9 | GRM1 | glutamate metabotropic receptor 1 [Source:HGNC Symbol;Acc:HGNC:4593] | 9670 | 0.000 | -0.2609 | No |
| 10 | GRM5 | glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597] | 9674 | 0.000 | -0.2610 | No |
| 11 | GRIN2C | glutamate ionotropic receptor NMDA type subunit 2C [Source:HGNC Symbol;Acc:HGNC:4587] | 10050 | 0.000 | -0.2711 | No |
| 12 | GRIN3A | glutamate ionotropic receptor NMDA type subunit 3A [Source:HGNC Symbol;Acc:HGNC:16767] | 10054 | 0.000 | -0.2712 | No |
| 13 | GLRA1 | glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326] | 12772 | 0.000 | -0.3446 | No |
| 14 | GLRA2 | glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327] | 12776 | 0.000 | -0.3447 | No |
| 15 | CHRFAM7A | CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion [Source:HGNC Symbol;Acc:HGNC:15781] | 13037 | 0.000 | -0.3517 | No |
| 16 | GABRE | gamma-aminobutyric acid type A receptor subunit epsilon [Source:HGNC Symbol;Acc:HGNC:4085] | 17244 | 0.000 | -0.4653 | No |
| 17 | CHRND | cholinergic receptor nicotinic delta subunit [Source:HGNC Symbol;Acc:HGNC:1965] | 17754 | 0.000 | -0.4790 | No |
| 18 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17755 | 0.000 | -0.4790 | No |
| 19 | CHRNE | cholinergic receptor nicotinic epsilon subunit [Source:HGNC Symbol;Acc:HGNC:1966] | 17756 | 0.000 | -0.4790 | No |
| 20 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17765 | 0.000 | -0.4792 | No |
| 21 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 17767 | 0.000 | -0.4793 | No |
| 22 | CHRM1 | cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950] | 17768 | 0.000 | -0.4793 | No |
| 23 | CHRM5 | cholinergic receptor muscarinic 5 [Source:HGNC Symbol;Acc:HGNC:1954] | 17769 | 0.000 | -0.4793 | No |
| 24 | ADRB1 | adrenoceptor beta 1 [Source:HGNC Symbol;Acc:HGNC:285] | 17874 | 0.000 | -0.4821 | No |
| 25 | DRD1 | dopamine receptor D1 [Source:HGNC Symbol;Acc:HGNC:3020] | 18409 | 0.000 | -0.4965 | No |
| 26 | DRD2 | dopamine receptor D2 [Source:HGNC Symbol;Acc:HGNC:3023] | 18410 | 0.000 | -0.4965 | No |
| 27 | DRD3 | dopamine receptor D3 [Source:HGNC Symbol;Acc:HGNC:3024] | 18412 | 0.000 | -0.4965 | No |
| 28 | DRD4 | dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025] | 18413 | 0.000 | -0.4965 | No |
| 29 | DRD5 | dopamine receptor D5 [Source:HGNC Symbol;Acc:HGNC:3026] | 18414 | 0.000 | -0.4965 | No |
| 30 | CHRNA10 | cholinergic receptor nicotinic alpha 10 subunit [Source:HGNC Symbol;Acc:HGNC:13800] | 19704 | 0.000 | -0.5313 | No |
| 31 | GABRG3 | gamma-aminobutyric acid type A receptor subunit gamma3 [Source:HGNC Symbol;Acc:HGNC:4088] | 19805 | 0.000 | -0.5340 | No |
| 32 | GABRG2 | gamma-aminobutyric acid type A receptor subunit gamma2 [Source:HGNC Symbol;Acc:HGNC:4087] | 19806 | 0.000 | -0.5340 | No |
| 33 | GABRG1 | gamma-aminobutyric acid type A receptor subunit gamma1 [Source:HGNC Symbol;Acc:HGNC:4086] | 19807 | 0.000 | -0.5340 | No |
| 34 | GABRB2 | gamma-aminobutyric acid type A receptor subunit beta2 [Source:HGNC Symbol;Acc:HGNC:4082] | 19855 | 0.000 | -0.5353 | No |
| 35 | GABRB1 | gamma-aminobutyric acid type A receptor subunit beta1 [Source:HGNC Symbol;Acc:HGNC:4081] | 19856 | 0.000 | -0.5353 | No |
| 36 | GABRA2 | gamma-aminobutyric acid type A receptor subunit alpha2 [Source:HGNC Symbol;Acc:HGNC:4076] | 19898 | 0.000 | -0.5364 | No |
| 37 | GABRA1 | gamma-aminobutyric acid type A receptor subunit alpha1 [Source:HGNC Symbol;Acc:HGNC:4075] | 19899 | 0.000 | -0.5364 | No |
| 38 | GABRA6 | gamma-aminobutyric acid type A receptor subunit alpha6 [Source:HGNC Symbol;Acc:HGNC:4080] | 19900 | 0.000 | -0.5364 | No |
| 39 | GABRA5 | gamma-aminobutyric acid type A receptor subunit alpha5 [Source:HGNC Symbol;Acc:HGNC:4079] | 19901 | 0.000 | -0.5364 | No |
| 40 | GABRA4 | gamma-aminobutyric acid type A receptor subunit alpha4 [Source:HGNC Symbol;Acc:HGNC:4078] | 19902 | 0.000 | -0.5364 | No |
| 41 | GABRA3 | gamma-aminobutyric acid type A receptor subunit alpha3 [Source:HGNC Symbol;Acc:HGNC:4077] | 19903 | 0.000 | -0.5364 | No |
| 42 | GABRR2 | gamma-aminobutyric acid type A receptor subunit rho2 [Source:HGNC Symbol;Acc:HGNC:4091] | 20039 | 0.000 | -0.5401 | No |
| 43 | GABRR1 | gamma-aminobutyric acid type A receptor subunit rho1 [Source:HGNC Symbol;Acc:HGNC:4090] | 20041 | 0.000 | -0.5401 | No |
| 44 | GLRB | glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329] | 21771 | 0.000 | -0.5868 | No |
| 45 | GABBR1 | gamma-aminobutyric acid type B receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:4070] | 22181 | 0.000 | -0.5978 | No |
| 46 | CHRNB3 | cholinergic receptor nicotinic beta 3 subunit [Source:HGNC Symbol;Acc:HGNC:1963] | 24624 | 0.000 | -0.6638 | No |
| 47 | CHRNA1 | cholinergic receptor nicotinic alpha 1 subunit [Source:HGNC Symbol;Acc:HGNC:1955] | 24647 | 0.000 | -0.6644 | No |
| 48 | CHRNA3 | cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957] | 24650 | 0.000 | -0.6644 | No |
| 49 | CHRNA2 | cholinergic receptor nicotinic alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:1956] | 24651 | 0.000 | -0.6644 | No |
| 50 | CHRNA5 | cholinergic receptor nicotinic alpha 5 subunit [Source:HGNC Symbol;Acc:HGNC:1959] | 24652 | 0.000 | -0.6644 | No |
| 51 | CHRNA4 | cholinergic receptor nicotinic alpha 4 subunit [Source:HGNC Symbol;Acc:HGNC:1958] | 24654 | 0.000 | -0.6645 | No |
| 52 | CHRNA7 | cholinergic receptor nicotinic alpha 7 subunit [Source:HGNC Symbol;Acc:HGNC:1960] | 24655 | 0.000 | -0.6645 | No |
| 53 | CHRNA6 | cholinergic receptor nicotinic alpha 6 subunit [Source:HGNC Symbol;Acc:HGNC:15963] | 24658 | 0.000 | -0.6645 | No |
| 54 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 24661 | 0.000 | -0.6646 | No |
| 55 | HRH3 | histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184] | 26641 | 0.000 | -0.7180 | No |
| 56 | HRH4 | histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383] | 26646 | 0.000 | -0.7181 | No |
| 57 | CHRNB1 | cholinergic receptor nicotinic beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:1961] | 30200 | -0.429 | -0.7571 | Yes |
| 58 | ANXA9 | annexin A9 [Source:HGNC Symbol;Acc:HGNC:547] | 32424 | -0.872 | -0.7013 | Yes |
| 59 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 33227 | -1.104 | -0.5762 | Yes |
| 60 | CHRNB4 | cholinergic receptor nicotinic beta 4 subunit [Source:HGNC Symbol;Acc:HGNC:1964] | 33433 | -1.168 | -0.4264 | Yes |
| 61 | GRIK5 | glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583] | 35201 | -1.932 | -0.2173 | Yes |
| 62 | CHRNB2 | cholinergic receptor nicotinic beta 2 subunit [Source:HGNC Symbol;Acc:HGNC:1962] | 35336 | -2.019 | 0.0474 | Yes |
