Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | HP_EMBRYONAL_NEOPLASM |
| Enrichment Score (ES) | -0.79517704 |
| Normalized Enrichment Score (NES) | -1.554364 |
| Nominal p-value | 0.0011764705 |
| FDR q-value | 0.12141766 |
| FWER p-Value | 0.911 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CDC73 | cell division cycle 73 [Source:HGNC Symbol;Acc:HGNC:16783] | 2615 | 0.705 | -0.0588 | No |
| 2 | TTC37 | tetratricopeptide repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:23639] | 4313 | 0.315 | -0.0993 | No |
| 3 | MSH3 | mutS homolog 3 [Source:HGNC Symbol;Acc:HGNC:7326] | 4919 | 0.196 | -0.1124 | No |
| 4 | PALB2 | partner and localizer of BRCA2 [Source:HGNC Symbol;Acc:HGNC:26144] | 5580 | 0.074 | -0.1290 | No |
| 5 | DHX37 | DEAH-box helicase 37 [Source:HGNC Symbol;Acc:HGNC:17210] | 5940 | 0.005 | -0.1386 | No |
| 6 | APC2 | APC regulator of WNT signaling pathway 2 [Source:HGNC Symbol;Acc:HGNC:24036] | 6314 | 0.000 | -0.1487 | No |
| 7 | DMRT3 | doublesex and mab-3 related transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:13909] | 9289 | 0.000 | -0.2290 | No |
| 8 | KCNQ1 | potassium voltage-gated channel subfamily Q member 1 [Source:HGNC Symbol;Acc:HGNC:6294] | 9567 | 0.000 | -0.2365 | No |
| 9 | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin [Source:HGNC Symbol;Acc:HGNC:9016] | 9579 | 0.000 | -0.2367 | No |
| 10 | RTL1 | retrotransposon Gag like 1 [Source:HGNC Symbol;Acc:HGNC:14665] | 10185 | 0.000 | -0.2531 | No |
| 11 | SRY | sex determining region Y [Source:HGNC Symbol;Acc:HGNC:11311] | 12244 | 0.000 | -0.3087 | No |
| 12 | IGF2 | insulin like growth factor 2 [Source:HGNC Symbol;Acc:HGNC:5466] | 12303 | 0.000 | -0.3102 | No |
| 13 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12454 | 0.000 | -0.3143 | No |
| 14 | BMPER | BMP binding endothelial regulator [Source:HGNC Symbol;Acc:HGNC:24154] | 12623 | 0.000 | -0.3188 | No |
| 15 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 13376 | 0.000 | -0.3391 | No |
| 16 | WT1 | WT1 transcription factor [Source:HGNC Symbol;Acc:HGNC:12796] | 13420 | 0.000 | -0.3403 | No |
| 17 | SETBP1 | SET binding protein 1 [Source:HGNC Symbol;Acc:HGNC:15573] | 13762 | 0.000 | -0.3495 | No |
| 18 | DZIP1L | DAZ interacting zinc finger protein 1 like [Source:HGNC Symbol;Acc:HGNC:26551] | 13990 | 0.000 | -0.3556 | No |
| 19 | MEG3 | maternally expressed 3 [Source:HGNC Symbol;Acc:HGNC:14575] | 16293 | 0.000 | -0.4178 | No |
| 20 | DLK1 | delta like non-canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:2907] | 16631 | 0.000 | -0.4269 | No |
| 21 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17064 | 0.000 | -0.4386 | No |
| 22 | NR0B1 | nuclear receptor subfamily 0 group B member 1 [Source:HGNC Symbol;Acc:HGNC:7960] | 18769 | 0.000 | -0.4846 | No |
| 23 | MNX1 | motor neuron and pancreas homeobox 1 [Source:HGNC Symbol;Acc:HGNC:4979] | 19443 | 0.000 | -0.5028 | No |
| 24 | GPC3 | glypican 3 [Source:HGNC Symbol;Acc:HGNC:4451] | 22976 | 0.000 | -0.5981 | No |
| 25 | GPC4 | glypican 4 [Source:HGNC Symbol;Acc:HGNC:4452] | 22982 | 0.000 | -0.5983 | No |
| 26 | ALX4 | ALX homeobox 4 [Source:HGNC Symbol;Acc:HGNC:450] | 24327 | 0.000 | -0.6346 | No |
| 27 | POU6F2 | POU class 6 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:21694] | 25221 | 0.000 | -0.6587 | No |
| 28 | SOX9 | SRY-box transcription factor 9 [Source:HGNC Symbol;Acc:HGNC:11204] | 25996 | 0.000 | -0.6796 | No |
| 29 | KCNQ1OT1 | KCNQ1 opposite strand/antisense transcript 1 [Source:HGNC Symbol;Acc:HGNC:6295] | 27488 | -0.023 | -0.7195 | No |
| 30 | ZFPM2 | zinc finger protein, FOG family member 2 [Source:HGNC Symbol;Acc:HGNC:16700] | 28856 | -0.227 | -0.7526 | No |
| 31 | VAMP7 | vesicle associated membrane protein 7 [Source:HGNC Symbol;Acc:HGNC:11486] | 29307 | -0.297 | -0.7597 | No |
| 32 | NR5A1 | nuclear receptor subfamily 5 group A member 1 [Source:HGNC Symbol;Acc:HGNC:7983] | 29485 | -0.324 | -0.7591 | No |
| 33 | DICER1 | dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098] | 29630 | -0.346 | -0.7572 | No |
| 34 | APC | APC regulator of WNT signaling pathway [Source:HGNC Symbol;Acc:HGNC:583] | 29675 | -0.351 | -0.7525 | No |
| 35 | SLC22A18 | solute carrier family 22 member 18 [Source:HGNC Symbol;Acc:HGNC:10964] | 29817 | -0.371 | -0.7500 | No |
| 36 | REST | RE1 silencing transcription factor [Source:HGNC Symbol;Acc:HGNC:9966] | 30039 | -0.404 | -0.7492 | No |
| 37 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:8975] | 31075 | -0.571 | -0.7676 | No |
| 38 | SKIV2L | Ski2 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:10898] | 31306 | -0.611 | -0.7636 | No |
| 39 | DIS3L2 | DIS3 like 3'-5' exoribonuclease 2 [Source:HGNC Symbol;Acc:HGNC:28648] | 31613 | -0.673 | -0.7605 | No |
| 40 | BUB3 | BUB3 mitotic checkpoint protein [Source:HGNC Symbol;Acc:HGNC:1151] | 32897 | -1.007 | -0.7783 | Yes |
| 41 | NSD1 | nuclear receptor binding SET domain protein 1 [Source:HGNC Symbol;Acc:HGNC:14234] | 33050 | -1.048 | -0.7648 | Yes |
| 42 | SETD2 | SET domain containing 2, histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:18420] | 33166 | -1.084 | -0.7497 | Yes |
| 43 | TP53 | tumor protein p53 [Source:HGNC Symbol;Acc:HGNC:11998] | 33554 | -1.213 | -0.7398 | Yes |
| 44 | HDAC4 | histone deacetylase 4 [Source:HGNC Symbol;Acc:HGNC:14063] | 33587 | -1.225 | -0.7202 | Yes |
| 45 | PTCH1 | patched 1 [Source:HGNC Symbol;Acc:HGNC:9585] | 33955 | -1.356 | -0.7073 | Yes |
| 46 | FIBP | FGF1 intracellular binding protein [Source:HGNC Symbol;Acc:HGNC:3705] | 34450 | -1.545 | -0.6947 | Yes |
| 47 | PHF21A | PHD finger protein 21A [Source:HGNC Symbol;Acc:HGNC:24156] | 34739 | -1.669 | -0.6745 | Yes |
| 48 | TRIM28 | tripartite motif containing 28 [Source:HGNC Symbol;Acc:HGNC:16384] | 34840 | -1.714 | -0.6485 | Yes |
| 49 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35064 | -1.841 | -0.6236 | Yes |
| 50 | EXT2 | exostosin glycosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:3513] | 35403 | -2.066 | -0.5981 | Yes |
| 51 | CEP57 | centrosomal protein 57 [Source:HGNC Symbol;Acc:HGNC:30794] | 35675 | -2.252 | -0.5676 | Yes |
| 52 | TRIM37 | tripartite motif containing 37 [Source:HGNC Symbol;Acc:HGNC:7523] | 35866 | -2.430 | -0.5320 | Yes |
| 53 | WWOX | WW domain containing oxidoreductase [Source:HGNC Symbol;Acc:HGNC:12799] | 35994 | -2.546 | -0.4927 | Yes |
| 54 | BLM | BLM RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:1058] | 36004 | -2.556 | -0.4501 | Yes |
| 55 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36239 | -2.787 | -0.4096 | Yes |
| 56 | CHEK2 | checkpoint kinase 2 [Source:HGNC Symbol;Acc:HGNC:16627] | 36690 | -3.417 | -0.3645 | Yes |
| 57 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6848] | 36704 | -3.438 | -0.3072 | Yes |
| 58 | BRCA2 | BRCA2 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1101] | 36707 | -3.439 | -0.2495 | Yes |
| 59 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36780 | -3.580 | -0.1914 | Yes |
| 60 | SLC37A4 | solute carrier family 37 member 4 [Source:HGNC Symbol;Acc:HGNC:4061] | 36842 | -3.750 | -0.1302 | Yes |
| 61 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36947 | -3.999 | -0.0659 | Yes |
| 62 | PAX6 | paired box 6 [Source:HGNC Symbol;Acc:HGNC:8620] | 36990 | -4.157 | 0.0027 | Yes |
