Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | CSR_EARLY_UP.V1_DN |
| Enrichment Score (ES) | -0.59627914 |
| Normalized Enrichment Score (NES) | -1.2555902 |
| Nominal p-value | 0.05934066 |
| FDR q-value | 0.3385031 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 91 | 4.106 | 0.0329 | No |
| 2 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 103 | 4.026 | 0.0672 | No |
| 3 | TRIM56 | tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028] | 389 | 2.648 | 0.0823 | No |
| 4 | IP6K2 | inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313] | 736 | 1.918 | 0.0894 | No |
| 5 | MINDY1 | MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648] | 979 | 1.596 | 0.0966 | No |
| 6 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 1391 | 1.252 | 0.0963 | No |
| 7 | NR1H3 | nuclear receptor subfamily 1 group H member 3 [Source:HGNC Symbol;Acc:HGNC:7966] | 1413 | 1.240 | 0.1064 | No |
| 8 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 1502 | 1.187 | 0.1142 | No |
| 9 | ZNF585B | zinc finger protein 585B [Source:HGNC Symbol;Acc:HGNC:30948] | 1576 | 1.158 | 0.1222 | No |
| 10 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 1788 | 1.041 | 0.1254 | No |
| 11 | LRIG2 | leucine rich repeats and immunoglobulin like domains 2 [Source:HGNC Symbol;Acc:HGNC:20889] | 2241 | 0.839 | 0.1204 | No |
| 12 | RNF20 | ring finger protein 20 [Source:HGNC Symbol;Acc:HGNC:10062] | 3278 | 0.533 | 0.0970 | No |
| 13 | GRHL1 | grainyhead like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:17923] | 3372 | 0.512 | 0.0989 | No |
| 14 | RABGAP1 | RAB GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:17155] | 3545 | 0.471 | 0.0983 | No |
| 15 | FBXO38 | F-box protein 38 [Source:HGNC Symbol;Acc:HGNC:28844] | 3659 | 0.447 | 0.0991 | No |
| 16 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 5015 | 0.176 | 0.0639 | No |
| 17 | ZNF500 | zinc finger protein 500 [Source:HGNC Symbol;Acc:HGNC:23716] | 5121 | 0.162 | 0.0625 | No |
| 18 | PLCD1 | phospholipase C delta 1 [Source:HGNC Symbol;Acc:HGNC:9060] | 5188 | 0.154 | 0.0620 | No |
| 19 | GTPBP8 | GTP binding protein 8 (putative) [Source:HGNC Symbol;Acc:HGNC:25007] | 5468 | 0.100 | 0.0553 | No |
| 20 | TCAIM | T cell activation inhibitor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25241] | 5490 | 0.095 | 0.0556 | No |
| 21 | CC2D1A | coiled-coil and C2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:30237] | 5735 | 0.047 | 0.0494 | No |
| 22 | DAAM2 | dishevelled associated activator of morphogenesis 2 [Source:HGNC Symbol;Acc:HGNC:18143] | 6584 | 0.000 | 0.0264 | No |
| 23 | ASPA | aspartoacylase [Source:HGNC Symbol;Acc:HGNC:756] | 7427 | 0.000 | 0.0037 | No |
| 24 | PMS2P1 | PMS1 homolog 2, mismatch repair system component pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9123] | 7564 | 0.000 | -0.0000 | No |
| 25 | TDRD6 | tudor domain containing 6 [Source:HGNC Symbol;Acc:HGNC:21339] | 8750 | 0.000 | -0.0321 | No |
| 26 | NDNF | neuron derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:26256] | 9204 | 0.000 | -0.0443 | No |
| 27 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 10031 | 0.000 | -0.0667 | No |
| 28 | GFRA1 | GDNF family receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4243] | 10940 | 0.000 | -0.0912 | No |
| 29 | ERAP2 | endoplasmic reticulum aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:29499] | 11191 | 0.000 | -0.0980 | No |
| 30 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 12725 | 0.000 | -0.1395 | No |
| 31 | GSDMB | gasdermin B [Source:HGNC Symbol;Acc:HGNC:23690] | 13029 | 0.000 | -0.1477 | No |
| 32 | CDRT4 | CMT1A duplicated region transcript 4 [Source:HGNC Symbol;Acc:HGNC:14383] | 13197 | 0.000 | -0.1522 | No |
| 33 | GDF5 | growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220] | 13258 | 0.000 | -0.1538 | No |
| 34 | PDE5A | phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784] | 13346 | 0.000 | -0.1562 | No |
| 35 | NYNRIN | NYN domain and retroviral integrase containing [Source:HGNC Symbol;Acc:HGNC:20165] | 13791 | 0.000 | -0.1682 | No |
| 36 | HOXA10 | homeobox A10 [Source:HGNC Symbol;Acc:HGNC:5100] | 14139 | 0.000 | -0.1776 | No |
| 37 | STOX1 | storkhead box 1 [Source:HGNC Symbol;Acc:HGNC:23508] | 15804 | 0.000 | -0.2226 | No |
| 38 | MAB21L1 | mab-21 like 1 [Source:HGNC Symbol;Acc:HGNC:6757] | 15810 | 0.000 | -0.2227 | No |
| 39 | SLC7A14 | solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326] | 16190 | 0.000 | -0.2330 | No |
| 40 | PAPLN | papilin, proteoglycan like sulfated glycoprotein [Source:HGNC Symbol;Acc:HGNC:19262] | 17841 | 0.000 | -0.2776 | No |
| 41 | C14orf132 | chromosome 14 open reading frame 132 [Source:HGNC Symbol;Acc:HGNC:20346] | 17859 | 0.000 | -0.2781 | No |
| 42 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18373 | 0.000 | -0.2920 | No |
| 43 | SULF1 | sulfatase 1 [Source:HGNC Symbol;Acc:HGNC:20391] | 21674 | 0.000 | -0.3812 | No |
| 44 | ZNF337 | zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809] | 22394 | 0.000 | -0.4007 | No |
| 45 | ZNF302 | zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848] | 22438 | 0.000 | -0.4018 | No |
| 46 | CYP2R1 | cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580] | 22634 | 0.000 | -0.4071 | No |
| 47 | CAVIN2 | caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690] | 23509 | 0.000 | -0.4308 | No |
| 48 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 25532 | 0.000 | -0.4855 | No |
| 49 | SNPH | syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931] | 25693 | 0.000 | -0.4898 | No |
| 50 | NSUN5P2 | NSUN5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16609] | 25887 | 0.000 | -0.4950 | No |
| 51 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 27136 | 0.000 | -0.5288 | No |
| 52 | SLC25A46 | solute carrier family 25 member 46 [Source:HGNC Symbol;Acc:HGNC:25198] | 27714 | -0.064 | -0.5438 | No |
| 53 | ZFP64 | ZFP64 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:15940] | 27799 | -0.077 | -0.5454 | No |
| 54 | SLC9A7 | solute carrier family 9 member A7 [Source:HGNC Symbol;Acc:HGNC:17123] | 27895 | -0.089 | -0.5472 | No |
| 55 | ZNF33A | zinc finger protein 33A [Source:HGNC Symbol;Acc:HGNC:13096] | 28001 | -0.103 | -0.5492 | No |
| 56 | CROCCP2 | CROCC pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:28170] | 28099 | -0.120 | -0.5508 | No |
| 57 | TENT5C | terminal nucleotidyltransferase 5C [Source:HGNC Symbol;Acc:HGNC:24712] | 28143 | -0.127 | -0.5509 | No |
| 58 | DXO | decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992] | 28267 | -0.144 | -0.5530 | No |
| 59 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 28407 | -0.165 | -0.5553 | No |
| 60 | PHIP | pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673] | 28477 | -0.175 | -0.5557 | No |
| 61 | STX16 | syntaxin 16 [Source:HGNC Symbol;Acc:HGNC:11431] | 28612 | -0.190 | -0.5576 | No |
| 62 | LTN1 | listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082] | 29243 | -0.288 | -0.5722 | No |
| 63 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:16629] | 29390 | -0.310 | -0.5735 | No |
| 64 | PAN2 | poly(A) specific ribonuclease subunit PAN2 [Source:HGNC Symbol;Acc:HGNC:20074] | 30066 | -0.408 | -0.5882 | No |
| 65 | SAG | S-antigen visual arrestin [Source:HGNC Symbol;Acc:HGNC:10521] | 30248 | -0.437 | -0.5894 | No |
| 66 | ADAMTSL4 | ADAMTS like 4 [Source:HGNC Symbol;Acc:HGNC:19706] | 30275 | -0.443 | -0.5863 | No |
| 67 | ELMOD3 | ELMO domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26158] | 30646 | -0.502 | -0.5920 | Yes |
| 68 | PRRT2 | proline rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30500] | 30660 | -0.504 | -0.5880 | Yes |
| 69 | MOSPD2 | motile sperm domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28381] | 30759 | -0.519 | -0.5862 | Yes |
| 70 | ABCC10 | ATP binding cassette subfamily C member 10 [Source:HGNC Symbol;Acc:HGNC:52] | 30794 | -0.525 | -0.5826 | Yes |
| 71 | MSRB1 | methionine sulfoxide reductase B1 [Source:HGNC Symbol;Acc:HGNC:14133] | 30805 | -0.527 | -0.5783 | Yes |
| 72 | ARL4D | ADP ribosylation factor like GTPase 4D [Source:HGNC Symbol;Acc:HGNC:656] | 31040 | -0.565 | -0.5798 | Yes |
| 73 | EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3290] | 31048 | -0.567 | -0.5751 | Yes |
| 74 | ATF7IP | activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092] | 31106 | -0.578 | -0.5716 | Yes |
| 75 | TFAP2A | transcription factor AP-2 alpha [Source:HGNC Symbol;Acc:HGNC:11742] | 31196 | -0.595 | -0.5689 | Yes |
| 76 | USP33 | ubiquitin specific peptidase 33 [Source:HGNC Symbol;Acc:HGNC:20059] | 31249 | -0.602 | -0.5652 | Yes |
| 77 | ZFYVE1 | zinc finger FYVE-type containing 1 [Source:HGNC Symbol;Acc:HGNC:13180] | 31338 | -0.619 | -0.5622 | Yes |
| 78 | AMT | aminomethyltransferase [Source:HGNC Symbol;Acc:HGNC:473] | 31376 | -0.629 | -0.5578 | Yes |
| 79 | LRRK2 | leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618] | 31413 | -0.634 | -0.5533 | Yes |
| 80 | LRIG3 | leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991] | 31518 | -0.655 | -0.5505 | Yes |
| 81 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 31586 | -0.668 | -0.5466 | Yes |
| 82 | FBXO25 | F-box protein 25 [Source:HGNC Symbol;Acc:HGNC:13596] | 31623 | -0.675 | -0.5417 | Yes |
| 83 | UBN2 | ubinuclein 2 [Source:HGNC Symbol;Acc:HGNC:21931] | 32273 | -0.831 | -0.5521 | Yes |
| 84 | ACYP1 | acylphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:179] | 32640 | -0.927 | -0.5541 | Yes |
| 85 | ZNF467 | zinc finger protein 467 [Source:HGNC Symbol;Acc:HGNC:23154] | 32718 | -0.950 | -0.5480 | Yes |
| 86 | ACBD4 | acyl-CoA binding domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23337] | 32747 | -0.957 | -0.5405 | Yes |
| 87 | SIX1 | SIX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10887] | 32748 | -0.957 | -0.5323 | Yes |
| 88 | POLL | DNA polymerase lambda [Source:HGNC Symbol;Acc:HGNC:9184] | 33068 | -1.052 | -0.5318 | Yes |
| 89 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 33106 | -1.065 | -0.5237 | Yes |
| 90 | HEBP2 | heme binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15716] | 33457 | -1.174 | -0.5230 | Yes |
| 91 | ALDH1L2 | aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777] | 33540 | -1.206 | -0.5149 | Yes |
| 92 | YEATS2 | YEATS domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25489] | 33640 | -1.246 | -0.5068 | Yes |
| 93 | KBTBD6 | kelch repeat and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:25340] | 33848 | -1.319 | -0.5011 | Yes |
| 94 | DCP1B | decapping mRNA 1B [Source:HGNC Symbol;Acc:HGNC:24451] | 34099 | -1.403 | -0.4958 | Yes |
| 95 | OTUD1 | OTU deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:27346] | 34101 | -1.406 | -0.4837 | Yes |
| 96 | ARRDC3 | arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263] | 34182 | -1.441 | -0.4735 | Yes |
| 97 | ZNF226 | zinc finger protein 226 [Source:HGNC Symbol;Acc:HGNC:13019] | 34211 | -1.452 | -0.4617 | Yes |
| 98 | CIRBP | cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982] | 34240 | -1.462 | -0.4499 | Yes |
| 99 | SIX5 | SIX homeobox 5 [Source:HGNC Symbol;Acc:HGNC:10891] | 34284 | -1.481 | -0.4383 | Yes |
| 100 | ALDH3B2 | aldehyde dehydrogenase 3 family member B2 [Source:HGNC Symbol;Acc:HGNC:411] | 34382 | -1.518 | -0.4279 | Yes |
| 101 | BRD8 | bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874] | 34385 | -1.519 | -0.4149 | Yes |
| 102 | NDUFAF7 | NADH:ubiquinone oxidoreductase complex assembly factor 7 [Source:HGNC Symbol;Acc:HGNC:28816] | 34568 | -1.589 | -0.4061 | Yes |
| 103 | UFSP2 | UFM1 specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:25640] | 34671 | -1.638 | -0.3948 | Yes |
| 104 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 34742 | -1.670 | -0.3823 | Yes |
| 105 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 34769 | -1.684 | -0.3685 | Yes |
| 106 | NATD1 | N-acetyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30770] | 34878 | -1.739 | -0.3565 | Yes |
| 107 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 34884 | -1.741 | -0.3416 | Yes |
| 108 | NPHP3 | nephrocystin 3 [Source:HGNC Symbol;Acc:HGNC:7907] | 34905 | -1.756 | -0.3271 | Yes |
| 109 | HBP1 | HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200] | 35110 | -1.871 | -0.3165 | Yes |
| 110 | MPPE1 | metallophosphoesterase 1 [Source:HGNC Symbol;Acc:HGNC:15988] | 35161 | -1.907 | -0.3014 | Yes |
| 111 | NMT2 | N-myristoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:7858] | 35232 | -1.953 | -0.2865 | Yes |
| 112 | DDX17 | DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740] | 35295 | -1.993 | -0.2711 | Yes |
| 113 | AKIP1 | A-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1170] | 35351 | -2.026 | -0.2551 | Yes |
| 114 | CDKN1B | cyclin dependent kinase inhibitor 1B [Source:HGNC Symbol;Acc:HGNC:1785] | 35418 | -2.075 | -0.2390 | Yes |
| 115 | LDB1 | LIM domain binding 1 [Source:HGNC Symbol;Acc:HGNC:6532] | 35645 | -2.232 | -0.2260 | Yes |
| 116 | ING4 | inhibitor of growth family member 4 [Source:HGNC Symbol;Acc:HGNC:19423] | 35684 | -2.264 | -0.2075 | Yes |
| 117 | CKB | creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991] | 35726 | -2.303 | -0.1888 | Yes |
| 118 | SLC16A7 | solute carrier family 16 member 7 [Source:HGNC Symbol;Acc:HGNC:10928] | 35741 | -2.320 | -0.1692 | Yes |
| 119 | ANKZF1 | ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:25527] | 35841 | -2.411 | -0.1512 | Yes |
| 120 | MRI1 | methylthioribose-1-phosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:28469] | 35989 | -2.541 | -0.1333 | Yes |
| 121 | C2CD5 | C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062] | 36113 | -2.665 | -0.1137 | Yes |
| 122 | FUT10 | fucosyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19234] | 36154 | -2.712 | -0.0914 | Yes |
| 123 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36442 | -3.043 | -0.0730 | Yes |
| 124 | FZD2 | frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040] | 36533 | -3.167 | -0.0482 | Yes |
| 125 | ACCS | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) [Source:HGNC Symbol;Acc:HGNC:23989] | 36782 | -3.588 | -0.0240 | Yes |
| 126 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36844 | -3.755 | 0.0067 | Yes |
