Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | KRAS.KIDNEY_UP.V1_DN |
| Enrichment Score (ES) | 0.52337646 |
| Normalized Enrichment Score (NES) | 1.3636289 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07682535 |
| FWER p-Value | 0.216 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 15 | 4.872 | 0.0569 | Yes |
| 2 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 20 | 4.828 | 0.1136 | Yes |
| 3 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 29 | 4.760 | 0.1694 | Yes |
| 4 | PTGER2 | prostaglandin E receptor 2 [Source:HGNC Symbol;Acc:HGNC:9594] | 41 | 4.583 | 0.2230 | Yes |
| 5 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 154 | 3.699 | 0.2635 | Yes |
| 6 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 251 | 3.171 | 0.2982 | Yes |
| 7 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283] | 309 | 2.900 | 0.3308 | Yes |
| 8 | ETS1 | ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488] | 363 | 2.724 | 0.3614 | Yes |
| 9 | ACTC1 | actin alpha cardiac muscle 1 [Source:HGNC Symbol;Acc:HGNC:143] | 395 | 2.636 | 0.3915 | Yes |
| 10 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 444 | 2.489 | 0.4195 | Yes |
| 11 | PDCD1 | programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760] | 448 | 2.477 | 0.4486 | Yes |
| 12 | EFHD1 | EF-hand domain family member D1 [Source:HGNC Symbol;Acc:HGNC:29556] | 573 | 2.181 | 0.4709 | Yes |
| 13 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 802 | 1.811 | 0.4860 | Yes |
| 14 | NES | nestin [Source:HGNC Symbol;Acc:HGNC:7756] | 834 | 1.775 | 0.5060 | Yes |
| 15 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 1502 | 1.187 | 0.5020 | Yes |
| 16 | HINFP | histone H4 transcription factor [Source:HGNC Symbol;Acc:HGNC:17850] | 1610 | 1.141 | 0.5125 | Yes |
| 17 | KCND1 | potassium voltage-gated channel subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:6237] | 1686 | 1.099 | 0.5234 | Yes |
| 18 | LIPE | lipase E, hormone sensitive type [Source:HGNC Symbol;Acc:HGNC:6621] | 2424 | 0.771 | 0.5125 | No |
| 19 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 2890 | 0.626 | 0.5073 | No |
| 20 | KCNN1 | potassium calcium-activated channel subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:6290] | 3092 | 0.580 | 0.5087 | No |
| 21 | DDX51 | DEAD-box helicase 51 [Source:HGNC Symbol;Acc:HGNC:20082] | 3615 | 0.455 | 0.4999 | No |
| 22 | IL23A | interleukin 23 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15488] | 3830 | 0.416 | 0.4990 | No |
| 23 | FOLR2 | folate receptor beta [Source:HGNC Symbol;Acc:HGNC:3793] | 4170 | 0.347 | 0.4939 | No |
| 24 | CBARP | CACN subunit beta associated regulatory protein [Source:HGNC Symbol;Acc:HGNC:28617] | 4289 | 0.321 | 0.4945 | No |
| 25 | RBIS | ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:32235] | 4633 | 0.246 | 0.4881 | No |
| 26 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 4688 | 0.239 | 0.4894 | No |
| 27 | EGFL7 | EGF like domain multiple 7 [Source:HGNC Symbol;Acc:HGNC:20594] | 5197 | 0.152 | 0.4775 | No |
| 28 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 5202 | 0.152 | 0.4792 | No |
| 29 | THRB | thyroid hormone receptor beta [Source:HGNC Symbol;Acc:HGNC:11799] | 5567 | 0.077 | 0.4702 | No |
| 30 | RPL10P17 | ribosomal protein L10 pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:52348] | 5626 | 0.066 | 0.4694 | No |
| 31 | CBL | Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541] | 5769 | 0.040 | 0.4661 | No |
| 32 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6046 | 0.000 | 0.4586 | No |
| 33 | CCL27 | C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626] | 6064 | 0.000 | 0.4581 | No |
| 34 | IL1RL2 | interleukin 1 receptor like 2 [Source:HGNC Symbol;Acc:HGNC:5999] | 6567 | 0.000 | 0.4445 | No |
| 35 | EPHA5 | EPH receptor A5 [Source:HGNC Symbol;Acc:HGNC:3389] | 7088 | 0.000 | 0.4305 | No |
| 36 | ASPN | asporin [Source:HGNC Symbol;Acc:HGNC:14872] | 7415 | 0.000 | 0.4217 | No |
| 37 | SGK2 | serum/glucocorticoid regulated kinase 2 [Source:HGNC Symbol;Acc:HGNC:13900] | 7516 | 0.000 | 0.4189 | No |
| 38 | OR7A10 | olfactory receptor family 7 subfamily A member 10 [Source:HGNC Symbol;Acc:HGNC:8356] | 7732 | 0.000 | 0.4131 | No |
| 39 | PROP1 | PROP paired-like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9455] | 7978 | 0.000 | 0.4065 | No |
| 40 | SIM1 | SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882] | 8025 | 0.000 | 0.4053 | No |
| 41 | SERHL2 | serine hydrolase like 2 [Source:HGNC Symbol;Acc:HGNC:29446] | 9294 | 0.000 | 0.3709 | No |
| 42 | KCNF1 | potassium voltage-gated channel modifier subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:6246] | 9507 | 0.000 | 0.3652 | No |
| 43 | CETP | cholesteryl ester transfer protein [Source:HGNC Symbol;Acc:HGNC:1869] | 9576 | 0.000 | 0.3634 | No |
| 44 | GRM2 | glutamate metabotropic receptor 2 [Source:HGNC Symbol;Acc:HGNC:4594] | 9672 | 0.000 | 0.3608 | No |
| 45 | GRM4 | glutamate metabotropic receptor 4 [Source:HGNC Symbol;Acc:HGNC:4596] | 9675 | 0.000 | 0.3607 | No |
| 46 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 9678 | 0.000 | 0.3607 | No |
| 47 | AADAC | arylacetamide deacetylase [Source:HGNC Symbol;Acc:HGNC:17] | 10084 | 0.000 | 0.3497 | No |
| 48 | LRRC31 | leucine rich repeat containing 31 [Source:HGNC Symbol;Acc:HGNC:26261] | 11101 | 0.000 | 0.3222 | No |
| 49 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11204 | 0.000 | 0.3195 | No |
| 50 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11211 | 0.000 | 0.3193 | No |
| 51 | PRG2 | proteoglycan 2, pro eosinophil major basic protein [Source:HGNC Symbol;Acc:HGNC:9362] | 11230 | 0.000 | 0.3188 | No |
| 52 | LMAN1L | lectin, mannose binding 1 like [Source:HGNC Symbol;Acc:HGNC:6632] | 11541 | 0.000 | 0.3104 | No |
| 53 | SLC6A20 | solute carrier family 6 member 20 [Source:HGNC Symbol;Acc:HGNC:30927] | 11565 | 0.000 | 0.3098 | No |
| 54 | RYR2 | ryanodine receptor 2 [Source:HGNC Symbol;Acc:HGNC:10484] | 11590 | 0.000 | 0.3092 | No |
| 55 | AGRP | agouti related neuropeptide [Source:HGNC Symbol;Acc:HGNC:330] | 11820 | 0.000 | 0.3030 | No |
| 56 | CNN1 | calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155] | 11992 | 0.000 | 0.2983 | No |
| 57 | ADAMTSL2 | ADAMTS like 2 [Source:HGNC Symbol;Acc:HGNC:14631] | 12465 | 0.000 | 0.2856 | No |
| 58 | TENM2 | teneurin transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:29943] | 12587 | 0.000 | 0.2823 | No |
| 59 | TACR2 | tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11527] | 13041 | 0.000 | 0.2700 | No |
| 60 | LILRA4 | leukocyte immunoglobulin like receptor A4 [Source:HGNC Symbol;Acc:HGNC:15503] | 13276 | 0.000 | 0.2637 | No |
| 61 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13283 | 0.000 | 0.2635 | No |
| 62 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 13376 | 0.000 | 0.2611 | No |
| 63 | IL26 | interleukin 26 [Source:HGNC Symbol;Acc:HGNC:17119] | 13612 | 0.000 | 0.2547 | No |
| 64 | KRT2 | keratin 2 [Source:HGNC Symbol;Acc:HGNC:6439] | 14005 | 0.000 | 0.2441 | No |
| 65 | B3GALT5 | beta-1,3-galactosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:920] | 14329 | 0.000 | 0.2353 | No |
| 66 | NPC1L1 | NPC1 like intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7898] | 15921 | 0.000 | 0.1923 | No |
| 67 | C3orf36 | chromosome 3 putative open reading frame 36 [Source:HGNC Symbol;Acc:HGNC:26170] | 15949 | 0.000 | 0.1916 | No |
| 68 | MDFI | MyoD family inhibitor [Source:HGNC Symbol;Acc:HGNC:6967] | 16090 | 0.000 | 0.1878 | No |
| 69 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16110 | 0.000 | 0.1873 | No |
| 70 | HYAL4 | hyaluronidase 4 [Source:HGNC Symbol;Acc:HGNC:5323] | 16198 | 0.000 | 0.1849 | No |
| 71 | HRG | histidine rich glycoprotein [Source:HGNC Symbol;Acc:HGNC:5181] | 17420 | 0.000 | 0.1519 | No |
| 72 | SLC9A3 | solute carrier family 9 member A3 [Source:HGNC Symbol;Acc:HGNC:11073] | 17492 | 0.000 | 0.1500 | No |
| 73 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17755 | 0.000 | 0.1429 | No |
| 74 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17765 | 0.000 | 0.1426 | No |
| 75 | IFNA17 | interferon alpha 17 [Source:HGNC Symbol;Acc:HGNC:5422] | 18119 | 0.000 | 0.1331 | No |
| 76 | PTPRCAP | protein tyrosine phosphatase receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667] | 18125 | 0.000 | 0.1329 | No |
| 77 | DSG3 | desmoglein 3 [Source:HGNC Symbol;Acc:HGNC:3050] | 18865 | 0.000 | 0.1129 | No |
| 78 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 18981 | 0.000 | 0.1098 | No |
| 79 | BMP4 | bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071] | 19004 | 0.000 | 0.1092 | No |
| 80 | EPS8L3 | EPS8 like 3 [Source:HGNC Symbol;Acc:HGNC:21297] | 19068 | 0.000 | 0.1075 | No |
| 81 | NGF | nerve growth factor [Source:HGNC Symbol;Acc:HGNC:7808] | 19203 | 0.000 | 0.1039 | No |
| 82 | HSD17B2 | hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211] | 19703 | 0.000 | 0.0904 | No |
| 83 | VILL | villin like [Source:HGNC Symbol;Acc:HGNC:30906] | 19744 | 0.000 | 0.0893 | No |
| 84 | NR1I3 | nuclear receptor subfamily 1 group I member 3 [Source:HGNC Symbol;Acc:HGNC:7969] | 19879 | 0.000 | 0.0857 | No |
| 85 | KLHDC8A | kelch domain containing 8A [Source:HGNC Symbol;Acc:HGNC:25573] | 20030 | 0.000 | 0.0816 | No |
| 86 | TCF21 | transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11632] | 20409 | 0.000 | 0.0714 | No |
| 87 | KLK1 | kallikrein 1 [Source:HGNC Symbol;Acc:HGNC:6357] | 20600 | 0.000 | 0.0663 | No |
| 88 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 20996 | 0.000 | 0.0556 | No |
| 89 | INSL5 | insulin like 5 [Source:HGNC Symbol;Acc:HGNC:6088] | 21737 | 0.000 | 0.0355 | No |
| 90 | INSL4 | insulin like 4 [Source:HGNC Symbol;Acc:HGNC:6087] | 21738 | 0.000 | 0.0355 | No |
| 91 | KRT17 | keratin 17 [Source:HGNC Symbol;Acc:HGNC:6427] | 21877 | 0.000 | 0.0318 | No |
| 92 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875] | 22796 | 0.000 | 0.0070 | No |
| 93 | ATP1B4 | ATPase Na+/K+ transporting family member beta 4 [Source:HGNC Symbol;Acc:HGNC:808] | 23174 | 0.000 | -0.0032 | No |
| 94 | FOXA1 | forkhead box A1 [Source:HGNC Symbol;Acc:HGNC:5021] | 23520 | 0.000 | -0.0126 | No |
| 95 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 23524 | 0.000 | -0.0126 | No |
| 96 | NPPB | natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940] | 23525 | 0.000 | -0.0126 | No |
| 97 | TCP10L3 | t-complex 10 like 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:11656] | 23684 | 0.000 | -0.0169 | No |
| 98 | IGKV3D-15 | immunoglobulin kappa variable 3D-15 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5824] | 23700 | 0.000 | -0.0173 | No |
| 99 | NPFFR1 | neuropeptide FF receptor 1 [Source:HGNC Symbol;Acc:HGNC:17425] | 24093 | 0.000 | -0.0279 | No |
| 100 | CST5 | cystatin D [Source:HGNC Symbol;Acc:HGNC:2477] | 24593 | 0.000 | -0.0414 | No |
| 101 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 24661 | 0.000 | -0.0433 | No |
| 102 | PRSS21 | serine protease 21 [Source:HGNC Symbol;Acc:HGNC:9485] | 25132 | 0.000 | -0.0560 | No |
| 103 | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 25578 | 0.000 | -0.0680 | No |
| 104 | CAPN9 | calpain 9 [Source:HGNC Symbol;Acc:HGNC:1486] | 25769 | 0.000 | -0.0732 | No |
| 105 | PAGE1 | PAGE family member 1 [Source:HGNC Symbol;Acc:HGNC:4107] | 26378 | 0.000 | -0.0896 | No |
| 106 | MAGEA10 | MAGE family member A10 [Source:HGNC Symbol;Acc:HGNC:6797] | 26384 | 0.000 | -0.0897 | No |
| 107 | ITIH5 | inter-alpha-trypsin inhibitor heavy chain 5 [Source:HGNC Symbol;Acc:HGNC:21449] | 26789 | 0.000 | -0.1007 | No |
| 108 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 26972 | 0.000 | -0.1056 | No |
| 109 | BAAT | bile acid-CoA:amino acid N-acyltransferase [Source:HGNC Symbol;Acc:HGNC:932] | 26995 | 0.000 | -0.1062 | No |
| 110 | HHIPL2 | HHIP like 2 [Source:HGNC Symbol;Acc:HGNC:25842] | 28059 | -0.113 | -0.1336 | No |
| 111 | TMEM262 | transmembrane protein 262 [Source:HGNC Symbol;Acc:HGNC:49389] | 28299 | -0.149 | -0.1383 | No |
| 112 | CARD9 | caspase recruitment domain family member 9 [Source:HGNC Symbol;Acc:HGNC:16391] | 28336 | -0.156 | -0.1375 | No |
| 113 | BRDT | bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105] | 28587 | -0.187 | -0.1421 | No |
| 114 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 28622 | -0.192 | -0.1407 | No |
| 115 | CLEC3B | C-type lectin domain family 3 member B [Source:HGNC Symbol;Acc:HGNC:11891] | 29514 | -0.329 | -0.1610 | No |
| 116 | PHLDA3 | pleckstrin homology like domain family A member 3 [Source:HGNC Symbol;Acc:HGNC:8934] | 30051 | -0.406 | -0.1707 | No |
| 117 | FCHO1 | FCH and mu domain containing endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29002] | 30347 | -0.453 | -0.1734 | No |
| 118 | CACNA1S | calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397] | 31092 | -0.574 | -0.1867 | No |
| 119 | ZDHHC8P1 | ZDHHC8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:26461] | 31171 | -0.590 | -0.1819 | No |
| 120 | KLF3 | Kruppel like factor 3 [Source:HGNC Symbol;Acc:HGNC:16516] | 31272 | -0.606 | -0.1775 | No |
| 121 | SEC31B | SEC31 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:23197] | 31384 | -0.630 | -0.1731 | No |
| 122 | GPR35 | G protein-coupled receptor 35 [Source:HGNC Symbol;Acc:HGNC:4492] | 31502 | -0.652 | -0.1686 | No |
| 123 | H2AC13 | H2A clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:4725] | 31644 | -0.678 | -0.1644 | No |
| 124 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 31733 | -0.697 | -0.1586 | No |
| 125 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 33251 | -1.113 | -0.1865 | No |
| 126 | DEPDC5 | DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423] | 34263 | -1.472 | -0.1966 | No |
| 127 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 34274 | -1.478 | -0.1795 | No |
| 128 | TYROBP | transmembrane immune signaling adaptor TYROBP [Source:HGNC Symbol;Acc:HGNC:12449] | 34546 | -1.577 | -0.1683 | No |
| 129 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 35185 | -1.923 | -0.1629 | No |
| 130 | ECEL1 | endothelin converting enzyme like 1 [Source:HGNC Symbol;Acc:HGNC:3147] | 35918 | -2.476 | -0.1536 | No |
| 131 | KIF21B | kinesin family member 21B [Source:HGNC Symbol;Acc:HGNC:29442] | 35967 | -2.519 | -0.1252 | No |
| 132 | ABCA3 | ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33] | 36121 | -2.676 | -0.0979 | No |
| 133 | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560] | 36302 | -2.848 | -0.0693 | No |
| 134 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 36864 | -3.794 | -0.0398 | No |
| 135 | TREM2 | triggering receptor expressed on myeloid cells 2 [Source:HGNC Symbol;Acc:HGNC:17761] | 36903 | -3.903 | 0.0051 | No |
