Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | RB_DN.V1_DN |
| Enrichment Score (ES) | 0.5218966 |
| Normalized Enrichment Score (NES) | 1.3955506 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0743144 |
| FWER p-Value | 0.165 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 2 | 4.992 | 0.0390 | Yes |
| 2 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 35 | 4.665 | 0.0746 | Yes |
| 3 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 67 | 4.339 | 0.1077 | Yes |
| 4 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 84 | 4.181 | 0.1400 | Yes |
| 5 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 86 | 4.162 | 0.1725 | Yes |
| 6 | PSMB10 | proteasome 20S subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538] | 206 | 3.402 | 0.1959 | Yes |
| 7 | CISH | cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] | 231 | 3.257 | 0.2207 | Yes |
| 8 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 241 | 3.211 | 0.2456 | Yes |
| 9 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 308 | 2.903 | 0.2665 | Yes |
| 10 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 342 | 2.791 | 0.2874 | Yes |
| 11 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 397 | 2.625 | 0.3065 | Yes |
| 12 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 412 | 2.569 | 0.3262 | Yes |
| 13 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 468 | 2.436 | 0.3438 | Yes |
| 14 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 473 | 2.422 | 0.3626 | Yes |
| 15 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] | 666 | 2.015 | 0.3732 | Yes |
| 16 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 680 | 1.985 | 0.3883 | Yes |
| 17 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 753 | 1.886 | 0.4011 | Yes |
| 18 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 774 | 1.859 | 0.4151 | Yes |
| 19 | ANKFY1 | ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763] | 839 | 1.769 | 0.4272 | Yes |
| 20 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 856 | 1.749 | 0.4405 | Yes |
| 21 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 890 | 1.704 | 0.4529 | Yes |
| 22 | BASP1 | brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957] | 972 | 1.603 | 0.4633 | Yes |
| 23 | SMIM3 | small integral membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:30248] | 1244 | 1.355 | 0.4665 | Yes |
| 24 | PRKAR1A | protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388] | 1640 | 1.123 | 0.4646 | Yes |
| 25 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 1685 | 1.099 | 0.4720 | Yes |
| 26 | MSMO1 | methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] | 1907 | 0.993 | 0.4738 | Yes |
| 27 | DYNLL1 | dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476] | 1922 | 0.986 | 0.4811 | Yes |
| 28 | DDX3Y | DEAD-box helicase 3 Y-linked [Source:HGNC Symbol;Acc:HGNC:2699] | 1945 | 0.971 | 0.4882 | Yes |
| 29 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 1989 | 0.949 | 0.4944 | Yes |
| 30 | P4HA1 | prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546] | 2429 | 0.769 | 0.4885 | Yes |
| 31 | SARAF | store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789] | 2556 | 0.725 | 0.4908 | Yes |
| 32 | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769] | 2608 | 0.706 | 0.4949 | Yes |
| 33 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 2813 | 0.645 | 0.4945 | Yes |
| 34 | NKAP | NFKB activating protein [Source:HGNC Symbol;Acc:HGNC:29873] | 2843 | 0.637 | 0.4987 | Yes |
| 35 | BCCIP | BRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNC:978] | 2891 | 0.626 | 0.5023 | Yes |
| 36 | STARD3NL | STARD3 N-terminal like [Source:HGNC Symbol;Acc:HGNC:19169] | 3107 | 0.576 | 0.5010 | Yes |
| 37 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 3202 | 0.552 | 0.5028 | Yes |
| 38 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 3273 | 0.534 | 0.5050 | Yes |
| 39 | LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606] | 3334 | 0.520 | 0.5075 | Yes |
| 40 | SH3BP5L | SH3 binding domain protein 5 like [Source:HGNC Symbol;Acc:HGNC:29360] | 3339 | 0.519 | 0.5114 | Yes |
| 41 | UBA5 | ubiquitin like modifier activating enzyme 5 [Source:HGNC Symbol;Acc:HGNC:23230] | 3368 | 0.513 | 0.5147 | Yes |
| 42 | LAMC2 | laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493] | 3384 | 0.510 | 0.5183 | Yes |
| 43 | DDIT3 | DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726] | 3522 | 0.475 | 0.5183 | Yes |
| 44 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 3575 | 0.463 | 0.5205 | Yes |
| 45 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 3735 | 0.433 | 0.5196 | Yes |
| 46 | EIF4E | eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287] | 3872 | 0.407 | 0.5191 | Yes |
| 47 | TMCC3 | transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199] | 3886 | 0.404 | 0.5219 | Yes |
| 48 | ARL1 | ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692] | 4167 | 0.347 | 0.5170 | No |
| 49 | PDCD6 | programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765] | 4258 | 0.327 | 0.5172 | No |
| 50 | TMEM50B | transmembrane protein 50B [Source:HGNC Symbol;Acc:HGNC:1280] | 4352 | 0.306 | 0.5170 | No |
| 51 | TMEM42 | transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444] | 4421 | 0.290 | 0.5175 | No |
| 52 | UNC119B | unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488] | 4474 | 0.284 | 0.5183 | No |
| 53 | PPP2R1B | protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303] | 4475 | 0.284 | 0.5205 | No |
| 54 | DDIT4 | DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944] | 4510 | 0.277 | 0.5218 | No |
| 55 | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217] | 4623 | 0.250 | 0.5207 | No |
| 56 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 4972 | 0.184 | 0.5127 | No |
| 57 | SLC7A3 | solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061] | 4985 | 0.181 | 0.5138 | No |
| 58 | LMAN1 | lectin, mannose binding 1 [Source:HGNC Symbol;Acc:HGNC:6631] | 5743 | 0.045 | 0.4937 | No |
| 59 | CALCB | calcitonin related polypeptide beta [Source:HGNC Symbol;Acc:HGNC:1438] | 8395 | 0.000 | 0.4220 | No |
| 60 | LCE5A | late cornified envelope 5A [Source:HGNC Symbol;Acc:HGNC:16614] | 9102 | 0.000 | 0.4029 | No |
| 61 | RASL11B | RAS like family 11 member B [Source:HGNC Symbol;Acc:HGNC:23804] | 9451 | 0.000 | 0.3934 | No |
| 62 | ADAM12 | ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190] | 9642 | 0.000 | 0.3883 | No |
| 63 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 10678 | 0.000 | 0.3603 | No |
| 64 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 10800 | 0.000 | 0.3570 | No |
| 65 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 10840 | 0.000 | 0.3560 | No |
| 66 | S100A16 | S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:20441] | 11406 | 0.000 | 0.3407 | No |
| 67 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11483 | 0.000 | 0.3386 | No |
| 68 | AGR3 | anterior gradient 3, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:24167] | 11805 | 0.000 | 0.3300 | No |
| 69 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12304 | 0.000 | 0.3165 | No |
| 70 | MOXD1 | monooxygenase DBH like 1 [Source:HGNC Symbol;Acc:HGNC:21063] | 12850 | 0.000 | 0.3017 | No |
| 71 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13668 | 0.000 | 0.2796 | No |
| 72 | TLL1 | tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843] | 13972 | 0.000 | 0.2714 | No |
| 73 | GJB2 | gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] | 15358 | 0.000 | 0.2340 | No |
| 74 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16285 | 0.000 | 0.2089 | No |
| 75 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17064 | 0.000 | 0.1879 | No |
| 76 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 17920 | 0.000 | 0.1648 | No |
| 77 | BNC1 | basonuclin 1 [Source:HGNC Symbol;Acc:HGNC:1081] | 19194 | 0.000 | 0.1303 | No |
| 78 | F2RL1 | F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538] | 21044 | 0.000 | 0.0803 | No |
| 79 | IRX4 | iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129] | 21767 | 0.000 | 0.0608 | No |
| 80 | CAV1 | caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527] | 22238 | 0.000 | 0.0481 | No |
| 81 | LRRC4 | leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586] | 22684 | 0.000 | 0.0360 | No |
| 82 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 23589 | 0.000 | 0.0116 | No |
| 83 | C18orf32 | chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690] | 24380 | 0.000 | -0.0098 | No |
| 84 | CST9 | cystatin 9 [Source:HGNC Symbol;Acc:HGNC:13261] | 24589 | 0.000 | -0.0154 | No |
| 85 | WNT3 | Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782] | 25001 | 0.000 | -0.0265 | No |
| 86 | FHL1 | four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702] | 25682 | 0.000 | -0.0449 | No |
| 87 | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870] | 26860 | 0.000 | -0.0768 | No |
| 88 | EFL1 | elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789] | 27407 | -0.006 | -0.0915 | No |
| 89 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 27603 | -0.044 | -0.0964 | No |
| 90 | FEZ2 | fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660] | 27952 | -0.095 | -0.1051 | No |
| 91 | GOSR2 | golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431] | 28164 | -0.130 | -0.1098 | No |
| 92 | CELSR1 | cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850] | 28575 | -0.186 | -0.1194 | No |
| 93 | NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733] | 28979 | -0.245 | -0.1284 | No |
| 94 | SEC23A | Sec23 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10701] | 29427 | -0.315 | -0.1380 | No |
| 95 | RPS2 | ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404] | 29462 | -0.321 | -0.1364 | No |
| 96 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 29898 | -0.382 | -0.1452 | No |
| 97 | ANKRD40 | ankyrin repeat domain 40 [Source:HGNC Symbol;Acc:HGNC:28233] | 30000 | -0.397 | -0.1448 | No |
| 98 | ANXA11 | annexin A11 [Source:HGNC Symbol;Acc:HGNC:535] | 30145 | -0.420 | -0.1455 | No |
| 99 | H2BC14 | H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750] | 30700 | -0.510 | -0.1565 | No |
| 100 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 30863 | -0.537 | -0.1566 | No |
| 101 | LIFR | LIF receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6597] | 30990 | -0.557 | -0.1557 | No |
| 102 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 31586 | -0.668 | -0.1666 | No |
| 103 | UROS | uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592] | 31861 | -0.719 | -0.1684 | No |
| 104 | CREB3L2 | cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720] | 31930 | -0.738 | -0.1644 | No |
| 105 | COL18A1 | collagen type XVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2195] | 32523 | -0.891 | -0.1735 | No |
| 106 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 33185 | -1.090 | -0.1828 | No |
| 107 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 33460 | -1.175 | -0.1810 | No |
| 108 | CDC42SE2 | CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547] | 33668 | -1.256 | -0.1768 | No |
| 109 | CYTH1 | cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501] | 33781 | -1.295 | -0.1697 | No |
| 110 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 34044 | -1.384 | -0.1660 | No |
| 111 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 34061 | -1.392 | -0.1555 | No |
| 112 | CTNNAL1 | catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] | 34079 | -1.396 | -0.1451 | No |
| 113 | TRAPPC12 | trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284] | 34278 | -1.479 | -0.1389 | No |
| 114 | DNAJC4 | DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271] | 34620 | -1.611 | -0.1355 | No |
| 115 | MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693] | 34796 | -1.696 | -0.1270 | No |
| 116 | PLXNA2 | plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100] | 35120 | -1.876 | -0.1210 | No |
| 117 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 35774 | -2.347 | -0.1203 | No |
| 118 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 35824 | -2.393 | -0.1030 | No |
| 119 | FAM102A | family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419] | 35837 | -2.410 | -0.0844 | No |
| 120 | H2BC4 | H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757] | 36236 | -2.786 | -0.0734 | No |
| 121 | NDRG1 | N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679] | 36909 | -3.920 | -0.0609 | No |
| 122 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36947 | -3.999 | -0.0307 | No |
| 123 | MYORG | myogenesis regulating glycosidase (putative) [Source:HGNC Symbol;Acc:HGNC:19918] | 37037 | -4.410 | 0.0014 | No |
