Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_P107_DN.V1_UP |
| Enrichment Score (ES) | -0.7182576 |
| Normalized Enrichment Score (NES) | -1.5069371 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03344133 |
| FWER p-Value | 0.039 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 131 | 3.894 | 0.0171 | No |
| 2 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 174 | 3.614 | 0.0352 | No |
| 3 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 352 | 2.745 | 0.0449 | No |
| 4 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 586 | 2.157 | 0.0501 | No |
| 5 | FBLN5 | fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602] | 590 | 2.151 | 0.0614 | No |
| 6 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 792 | 1.832 | 0.0657 | No |
| 7 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 986 | 1.591 | 0.0689 | No |
| 8 | SPIRE2 | spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623] | 1016 | 1.561 | 0.0764 | No |
| 9 | TRPV2 | transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082] | 1136 | 1.437 | 0.0808 | No |
| 10 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 4079 | 0.362 | 0.0031 | No |
| 11 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 4200 | 0.339 | 0.0017 | No |
| 12 | RBPMS2 | RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098] | 4778 | 0.224 | -0.0128 | No |
| 13 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 4810 | 0.217 | -0.0124 | No |
| 14 | KCNA1 | potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218] | 5144 | 0.162 | -0.0206 | No |
| 15 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 5177 | 0.156 | -0.0206 | No |
| 16 | CES5A | carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459] | 6361 | 0.000 | -0.0526 | No |
| 17 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 7756 | 0.000 | -0.0904 | No |
| 18 | CDH2 | cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759] | 9167 | 0.000 | -0.1285 | No |
| 19 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9381 | 0.000 | -0.1343 | No |
| 20 | ABAT | 4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23] | 10268 | 0.000 | -0.1582 | No |
| 21 | FBLN2 | fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601] | 10991 | 0.000 | -0.1778 | No |
| 22 | LYPD1 | LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] | 11756 | 0.000 | -0.1984 | No |
| 23 | BICC1 | BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351] | 12262 | 0.000 | -0.2121 | No |
| 24 | SLIT3 | slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087] | 12410 | 0.000 | -0.2161 | No |
| 25 | TEK | TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724] | 12422 | 0.000 | -0.2164 | No |
| 26 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12454 | 0.000 | -0.2172 | No |
| 27 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 12725 | 0.000 | -0.2245 | No |
| 28 | TMEM119 | transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884] | 13324 | 0.000 | -0.2407 | No |
| 29 | TMEM45B | transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194] | 14596 | 0.000 | -0.2751 | No |
| 30 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15955 | 0.000 | -0.3118 | No |
| 31 | SI | sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856] | 16184 | 0.000 | -0.3180 | No |
| 32 | EFS | embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898] | 16257 | 0.000 | -0.3199 | No |
| 33 | COL16A1 | collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193] | 16401 | 0.000 | -0.3238 | No |
| 34 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 16503 | 0.000 | -0.3265 | No |
| 35 | SRPX2 | sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668] | 17456 | 0.000 | -0.3523 | No |
| 36 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 18653 | 0.000 | -0.3847 | No |
| 37 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 18654 | 0.000 | -0.3847 | No |
| 38 | FKBP10 | FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169] | 18915 | 0.000 | -0.3917 | No |
| 39 | KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117] | 19582 | 0.000 | -0.4097 | No |
| 40 | LOXL1 | lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665] | 19725 | 0.000 | -0.4136 | No |
| 41 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 20292 | 0.000 | -0.4289 | No |
| 42 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 20996 | 0.000 | -0.4479 | No |
| 43 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21229 | 0.000 | -0.4542 | No |
| 44 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21757 | 0.000 | -0.4684 | No |
| 45 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 23982 | 0.000 | -0.5286 | No |
| 46 | COX6B2 | cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] | 24183 | 0.000 | -0.5340 | No |
| 47 | TSSC4 | tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386] | 24491 | 0.000 | -0.5423 | No |
| 48 | SNCG | synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141] | 25545 | 0.000 | -0.5708 | No |
| 49 | TCFL5 | transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646] | 28089 | -0.118 | -0.6390 | No |
| 50 | SAMD10 | sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129] | 28130 | -0.123 | -0.6394 | No |
| 51 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 28935 | -0.239 | -0.6599 | No |
| 52 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 29048 | -0.257 | -0.6616 | No |
| 53 | MRGPRF | MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828] | 29356 | -0.305 | -0.6682 | No |
| 54 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 29510 | -0.329 | -0.6706 | No |
| 55 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 29545 | -0.333 | -0.6698 | No |
| 56 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036] | 30060 | -0.408 | -0.6815 | No |
| 57 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845] | 30158 | -0.421 | -0.6819 | No |
| 58 | H1-10 | H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722] | 30313 | -0.448 | -0.6837 | No |
| 59 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 30539 | -0.484 | -0.6873 | No |
| 60 | BGN | biglycan [Source:HGNC Symbol;Acc:HGNC:1044] | 30657 | -0.504 | -0.6877 | No |
| 61 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 31016 | -0.561 | -0.6945 | No |
| 62 | ANAPC11 | anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452] | 31020 | -0.562 | -0.6916 | No |
| 63 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 31118 | -0.581 | -0.6911 | No |
| 64 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31383 | -0.630 | -0.6949 | No |
| 65 | BLVRB | biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063] | 31504 | -0.652 | -0.6947 | No |
| 66 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 31694 | -0.688 | -0.6961 | No |
| 67 | CDH11 | cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750] | 32269 | -0.830 | -0.7073 | No |
| 68 | TRPM1 | transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146] | 32676 | -0.937 | -0.7133 | Yes |
| 69 | PIDD1 | p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491] | 32746 | -0.957 | -0.7101 | Yes |
| 70 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32753 | -0.958 | -0.7052 | Yes |
| 71 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33208 | -1.098 | -0.7116 | Yes |
| 72 | DYNLT1 | dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697] | 33228 | -1.105 | -0.7063 | Yes |
| 73 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33397 | -1.158 | -0.7047 | Yes |
| 74 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 33412 | -1.163 | -0.6989 | Yes |
| 75 | NELFE | negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974] | 33415 | -1.164 | -0.6928 | Yes |
| 76 | IPO9 | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] | 33498 | -1.190 | -0.6887 | Yes |
| 77 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 33817 | -1.309 | -0.6903 | Yes |
| 78 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 34180 | -1.439 | -0.6925 | Yes |
| 79 | RHEBL1 | RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166] | 34257 | -1.469 | -0.6867 | Yes |
| 80 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 34448 | -1.544 | -0.6837 | Yes |
| 81 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 34476 | -1.554 | -0.6762 | Yes |
| 82 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 34524 | -1.572 | -0.6691 | Yes |
| 83 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34638 | -1.617 | -0.6636 | Yes |
| 84 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 34783 | -1.690 | -0.6585 | Yes |
| 85 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 34810 | -1.702 | -0.6502 | Yes |
| 86 | HEXD | hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307] | 34952 | -1.775 | -0.6446 | Yes |
| 87 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35085 | -1.852 | -0.6383 | Yes |
| 88 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35138 | -1.892 | -0.6297 | Yes |
| 89 | DCLRE1A | DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660] | 35144 | -1.895 | -0.6198 | Yes |
| 90 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 35348 | -2.023 | -0.6145 | Yes |
| 91 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 35373 | -2.046 | -0.6043 | Yes |
| 92 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 35432 | -2.082 | -0.5949 | Yes |
| 93 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35510 | -2.132 | -0.5856 | Yes |
| 94 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35755 | -2.327 | -0.5799 | Yes |
| 95 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 35779 | -2.351 | -0.5680 | Yes |
| 96 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35807 | -2.374 | -0.5562 | Yes |
| 97 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 35880 | -2.445 | -0.5452 | Yes |
| 98 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 36108 | -2.658 | -0.5372 | Yes |
| 99 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 36123 | -2.679 | -0.5234 | Yes |
| 100 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36129 | -2.683 | -0.5093 | Yes |
| 101 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36208 | -2.759 | -0.4967 | Yes |
| 102 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36251 | -2.795 | -0.4831 | Yes |
| 103 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36260 | -2.803 | -0.4684 | Yes |
| 104 | PAQR4 | progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386] | 36294 | -2.839 | -0.4542 | Yes |
| 105 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36350 | -2.926 | -0.4402 | Yes |
| 106 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36359 | -2.931 | -0.4249 | Yes |
| 107 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36361 | -2.936 | -0.4093 | Yes |
| 108 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36388 | -2.969 | -0.3943 | Yes |
| 109 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36428 | -3.019 | -0.3793 | Yes |
| 110 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36430 | -3.020 | -0.3633 | Yes |
| 111 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36438 | -3.035 | -0.3474 | Yes |
| 112 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36466 | -3.065 | -0.3319 | Yes |
| 113 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36511 | -3.130 | -0.3165 | Yes |
| 114 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36523 | -3.149 | -0.3001 | Yes |
| 115 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36546 | -3.187 | -0.2837 | Yes |
| 116 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36575 | -3.228 | -0.2674 | Yes |
| 117 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36576 | -3.229 | -0.2503 | Yes |
| 118 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 36607 | -3.272 | -0.2337 | Yes |
| 119 | TCF19 | transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629] | 36613 | -3.282 | -0.2164 | Yes |
| 120 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36658 | -3.366 | -0.1998 | Yes |
| 121 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36705 | -3.438 | -0.1828 | Yes |
| 122 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 36800 | -3.631 | -0.1661 | Yes |
| 123 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36817 | -3.672 | -0.1470 | Yes |
| 124 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36881 | -3.841 | -0.1283 | Yes |
| 125 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36939 | -3.976 | -0.1088 | Yes |
| 126 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36953 | -4.019 | -0.0878 | Yes |
| 127 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36969 | -4.093 | -0.0665 | Yes |
| 128 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 36979 | -4.110 | -0.0449 | Yes |
| 129 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 37029 | -4.385 | -0.0230 | Yes |
| 130 | VEGFB | vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681] | 37069 | -4.643 | 0.0006 | Yes |
