Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_P130_DN.V1_UP |
| Enrichment Score (ES) | -0.61071163 |
| Normalized Enrichment Score (NES) | -1.277494 |
| Nominal p-value | 0.043525573 |
| FDR q-value | 0.27409017 |
| FWER p-Value | 0.996 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 87 | 4.161 | 0.0280 | No |
| 2 | HMGA2 | high mobility group AT-hook 2 [Source:HGNC Symbol;Acc:HGNC:5009] | 289 | 2.982 | 0.0443 | No |
| 3 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 313 | 2.870 | 0.0647 | No |
| 4 | RGS16 | regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997] | 571 | 2.182 | 0.0736 | No |
| 5 | FST | follistatin [Source:HGNC Symbol;Acc:HGNC:3971] | 648 | 2.049 | 0.0865 | No |
| 6 | COL11A2 | collagen type XI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2187] | 788 | 1.835 | 0.0962 | No |
| 7 | PPP1R15B | protein phosphatase 1 regulatory subunit 15B [Source:HGNC Symbol;Acc:HGNC:14951] | 1057 | 1.515 | 0.1000 | No |
| 8 | QTRT1 | queuine tRNA-ribosyltransferase catalytic subunit 1 [Source:HGNC Symbol;Acc:HGNC:23797] | 1116 | 1.452 | 0.1090 | No |
| 9 | LITAF | lipopolysaccharide induced TNF factor [Source:HGNC Symbol;Acc:HGNC:16841] | 1207 | 1.384 | 0.1167 | No |
| 10 | ZNF428 | zinc finger protein 428 [Source:HGNC Symbol;Acc:HGNC:20804] | 1529 | 1.179 | 0.1166 | No |
| 11 | RIPK3 | receptor interacting serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:10021] | 1616 | 1.136 | 0.1226 | No |
| 12 | TAL2 | TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557] | 1841 | 1.018 | 0.1239 | No |
| 13 | TRAF2 | TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032] | 1979 | 0.955 | 0.1272 | No |
| 14 | FAM220A | family with sequence similarity 220 member A [Source:HGNC Symbol;Acc:HGNC:22422] | 2131 | 0.884 | 0.1296 | No |
| 15 | ATP2A1 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:811] | 2267 | 0.830 | 0.1320 | No |
| 16 | CASP7 | caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508] | 2675 | 0.682 | 0.1259 | No |
| 17 | LSM4 | LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17259] | 3115 | 0.573 | 0.1182 | No |
| 18 | MRAS | muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227] | 3697 | 0.439 | 0.1057 | No |
| 19 | SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 [Source:HGNC Symbol;Acc:HGNC:11153] | 4163 | 0.348 | 0.0957 | No |
| 20 | PDZK1 | PDZ domain containing 1 [Source:HGNC Symbol;Acc:HGNC:8821] | 4230 | 0.333 | 0.0963 | No |
| 21 | GPN3 | GPN-loop GTPase 3 [Source:HGNC Symbol;Acc:HGNC:30186] | 4387 | 0.299 | 0.0943 | No |
| 22 | EXOSC2 | exosome component 2 [Source:HGNC Symbol;Acc:HGNC:17097] | 5041 | 0.170 | 0.0779 | No |
| 23 | CYBA | cytochrome b-245 alpha chain [Source:HGNC Symbol;Acc:HGNC:2577] | 5270 | 0.136 | 0.0727 | No |
| 24 | ZBTB17 | zinc finger and BTB domain containing 17 [Source:HGNC Symbol;Acc:HGNC:12936] | 5304 | 0.129 | 0.0727 | No |
| 25 | RENBP | renin binding protein [Source:HGNC Symbol;Acc:HGNC:9959] | 5873 | 0.016 | 0.0575 | No |
| 26 | C11orf71 | chromosome 11 open reading frame 71 [Source:HGNC Symbol;Acc:HGNC:25937] | 6024 | 0.000 | 0.0534 | No |
| 27 | VSIG2 | V-set and immunoglobulin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17149] | 6136 | 0.000 | 0.0504 | No |
| 28 | MYOZ2 | myozenin 2 [Source:HGNC Symbol;Acc:HGNC:1330] | 6139 | 0.000 | 0.0504 | No |
| 29 | USP13 | ubiquitin specific peptidase 13 [Source:HGNC Symbol;Acc:HGNC:12611] | 6253 | 0.000 | 0.0473 | No |
| 30 | FGF10 | fibroblast growth factor 10 [Source:HGNC Symbol;Acc:HGNC:3666] | 6556 | 0.000 | 0.0391 | No |
| 31 | AQP5 | aquaporin 5 [Source:HGNC Symbol;Acc:HGNC:638] | 6712 | 0.000 | 0.0350 | No |
| 32 | ART1 | ADP-ribosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:723] | 7109 | 0.000 | 0.0242 | No |
| 33 | GREM2 | gremlin 2, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:17655] | 7882 | 0.000 | 0.0034 | No |
| 34 | SIM1 | SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882] | 8025 | 0.000 | -0.0005 | No |
| 35 | SIM2 | SIM bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10883] | 8026 | 0.000 | -0.0005 | No |
| 36 | B4GALT4 | beta-1,4-galactosyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:927] | 9334 | 0.000 | -0.0358 | No |
| 37 | PIWIL1 | piwi like RNA-mediated gene silencing 1 [Source:HGNC Symbol;Acc:HGNC:9007] | 9522 | 0.000 | -0.0409 | No |
| 38 | SLC22A3 | solute carrier family 22 member 3 [Source:HGNC Symbol;Acc:HGNC:10967] | 9888 | 0.000 | -0.0508 | No |
| 39 | FAM187A | family with sequence similarity 187 member A [Source:HGNC Symbol;Acc:HGNC:35153] | 10500 | 0.000 | -0.0673 | No |
| 40 | CRLF1 | cytokine receptor like factor 1 [Source:HGNC Symbol;Acc:HGNC:2364] | 10618 | 0.000 | -0.0705 | No |
| 41 | NKD2 | NKD inhibitor of WNT signaling pathway 2 [Source:HGNC Symbol;Acc:HGNC:17046] | 10963 | 0.000 | -0.0798 | No |
| 42 | MYLK | myosin light chain kinase [Source:HGNC Symbol;Acc:HGNC:7590] | 14213 | 0.000 | -0.1677 | No |
| 43 | NXNL1 | nucleoredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:25179] | 14641 | 0.000 | -0.1792 | No |
| 44 | RHOJ | ras homolog family member J [Source:HGNC Symbol;Acc:HGNC:688] | 14904 | 0.000 | -0.1863 | No |
| 45 | GC | GC vitamin D binding protein [Source:HGNC Symbol;Acc:HGNC:4187] | 16099 | 0.000 | -0.2186 | No |
| 46 | PCSK5 | proprotein convertase subtilisin/kexin type 5 [Source:HGNC Symbol;Acc:HGNC:8747] | 16195 | 0.000 | -0.2212 | No |
| 47 | SLC7A9 | solute carrier family 7 member 9 [Source:HGNC Symbol;Acc:HGNC:11067] | 16677 | 0.000 | -0.2342 | No |
| 48 | CRTAC1 | cartilage acidic protein 1 [Source:HGNC Symbol;Acc:HGNC:14882] | 16822 | 0.000 | -0.2381 | No |
| 49 | TEAD1 | TEA domain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11714] | 17074 | 0.000 | -0.2449 | No |
| 50 | SLC13A2 | solute carrier family 13 member 2 [Source:HGNC Symbol;Acc:HGNC:10917] | 17134 | 0.000 | -0.2465 | No |
| 51 | TWIST2 | twist family bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:20670] | 17172 | 0.000 | -0.2475 | No |
| 52 | TINAG | tubulointerstitial nephritis antigen [Source:HGNC Symbol;Acc:HGNC:14599] | 17208 | 0.000 | -0.2484 | No |
| 53 | KAZN | kazrin, periplakin interacting protein [Source:HGNC Symbol;Acc:HGNC:29173] | 17303 | 0.000 | -0.2510 | No |
| 54 | SEMA5B | semaphorin 5B [Source:HGNC Symbol;Acc:HGNC:10737] | 17766 | 0.000 | -0.2635 | No |
| 55 | NKX2-8 | NK2 homeobox 8 [Source:HGNC Symbol;Acc:HGNC:16364] | 19102 | 0.000 | -0.2996 | No |
| 56 | PF4 | platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861] | 19916 | 0.000 | -0.3216 | No |
| 57 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 20577 | 0.000 | -0.3395 | No |
| 58 | SNN | stannin [Source:HGNC Symbol;Acc:HGNC:11149] | 20888 | 0.000 | -0.3478 | No |
| 59 | RSPH9 | radial spoke head component 9 [Source:HGNC Symbol;Acc:HGNC:21057] | 22270 | 0.000 | -0.3852 | No |
| 60 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875] | 22796 | 0.000 | -0.3994 | No |
| 61 | FOXI1 | forkhead box I1 [Source:HGNC Symbol;Acc:HGNC:3815] | 23449 | 0.000 | -0.4170 | No |
| 62 | NPPB | natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940] | 23525 | 0.000 | -0.4191 | No |
| 63 | SULT1B1 | sulfotransferase family 1B member 1 [Source:HGNC Symbol;Acc:HGNC:17845] | 23912 | 0.000 | -0.4295 | No |
| 64 | CRB3 | crumbs cell polarity complex component 3 [Source:HGNC Symbol;Acc:HGNC:20237] | 23998 | 0.000 | -0.4318 | No |
| 65 | WNT2B | Wnt family member 2B [Source:HGNC Symbol;Acc:HGNC:12781] | 24678 | 0.000 | -0.4502 | No |
| 66 | SPATA13 | spermatogenesis associated 13 [Source:HGNC Symbol;Acc:HGNC:23222] | 24920 | 0.000 | -0.4567 | No |
| 67 | STMN3 | stathmin 3 [Source:HGNC Symbol;Acc:HGNC:15926] | 26963 | 0.000 | -0.5120 | No |
| 68 | ALK | ALK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:427] | 27138 | 0.000 | -0.5167 | No |
| 69 | AVP | arginine vasopressin [Source:HGNC Symbol;Acc:HGNC:894] | 27309 | 0.000 | -0.5213 | No |
| 70 | DUSP13 | dual specificity phosphatase 13 [Source:HGNC Symbol;Acc:HGNC:19681] | 27825 | -0.080 | -0.5346 | No |
| 71 | RGL3 | ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282] | 28029 | -0.107 | -0.5393 | No |
| 72 | RASD1 | ras related dexamethasone induced 1 [Source:HGNC Symbol;Acc:HGNC:15828] | 28788 | -0.215 | -0.5583 | No |
| 73 | HINT1 | histidine triad nucleotide binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4912] | 28806 | -0.218 | -0.5571 | No |
| 74 | GLIS2 | GLIS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:29450] | 29068 | -0.260 | -0.5623 | No |
| 75 | ERG | ETS transcription factor ERG [Source:HGNC Symbol;Acc:HGNC:3446] | 29144 | -0.271 | -0.5623 | No |
| 76 | MIGA2 | mitoguardin 2 [Source:HGNC Symbol;Acc:HGNC:23621] | 29436 | -0.317 | -0.5679 | No |
| 77 | EFTUD2 | elongation factor Tu GTP binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30858] | 30409 | -0.462 | -0.5908 | No |
| 78 | CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 [Source:HGNC Symbol;Acc:HGNC:28314] | 30490 | -0.475 | -0.5895 | No |
| 79 | EIF1B | eukaryotic translation initiation factor 1B [Source:HGNC Symbol;Acc:HGNC:30792] | 30538 | -0.484 | -0.5873 | No |
| 80 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 30896 | -0.541 | -0.5930 | No |
| 81 | ELOF1 | elongation factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:28691] | 31089 | -0.574 | -0.5940 | No |
| 82 | STAT5B | signal transducer and activator of transcription 5B [Source:HGNC Symbol;Acc:HGNC:11367] | 31601 | -0.670 | -0.6029 | No |
| 83 | RABEPK | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] | 31781 | -0.704 | -0.6026 | No |
| 84 | SDF2L1 | stromal cell derived factor 2 like 1 [Source:HGNC Symbol;Acc:HGNC:10676] | 32067 | -0.771 | -0.6047 | Yes |
| 85 | RAD51D | RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823] | 32290 | -0.836 | -0.6046 | Yes |
| 86 | RUVBL2 | RuvB like AAA ATPase 2 [Source:HGNC Symbol;Acc:HGNC:10475] | 32498 | -0.885 | -0.6037 | Yes |
| 87 | RASA4 | RAS p21 protein activator 4 [Source:HGNC Symbol;Acc:HGNC:23181] | 32683 | -0.940 | -0.6019 | Yes |
| 88 | OXLD1 | oxidoreductase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27901] | 32783 | -0.969 | -0.5975 | Yes |
| 89 | MBD3 | methyl-CpG binding domain protein 3 [Source:HGNC Symbol;Acc:HGNC:6918] | 32855 | -0.992 | -0.5922 | Yes |
| 90 | ANAPC5 | anaphase promoting complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:15713] | 33212 | -1.098 | -0.5938 | Yes |
| 91 | PARS2 | prolyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:30563] | 33371 | -1.151 | -0.5896 | Yes |
| 92 | ORC1 | origin recognition complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:8487] | 33656 | -1.251 | -0.5882 | Yes |
| 93 | POLR2I | RNA polymerase II subunit I [Source:HGNC Symbol;Acc:HGNC:9196] | 33686 | -1.261 | -0.5798 | Yes |
| 94 | MYG1 | MYG1 exonuclease [Source:HGNC Symbol;Acc:HGNC:17590] | 33757 | -1.284 | -0.5723 | Yes |
| 95 | GFER | growth factor, augmenter of liver regeneration [Source:HGNC Symbol;Acc:HGNC:4236] | 33760 | -1.285 | -0.5630 | Yes |
| 96 | CUEDC2 | CUE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28352] | 33849 | -1.319 | -0.5557 | Yes |
| 97 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 33884 | -1.331 | -0.5469 | Yes |
| 98 | HYAL3 | hyaluronidase 3 [Source:HGNC Symbol;Acc:HGNC:5322] | 33999 | -1.371 | -0.5400 | Yes |
| 99 | NSMCE1 | NSE1 homolog, SMC5-SMC6 complex component [Source:HGNC Symbol;Acc:HGNC:29897] | 34008 | -1.373 | -0.5302 | Yes |
| 100 | CHCHD6 | coiled-coil-helix-coiled-coil-helix domain containing 6 [Source:HGNC Symbol;Acc:HGNC:28184] | 34054 | -1.389 | -0.5213 | Yes |
| 101 | GRTP1 | growth hormone regulated TBC protein 1 [Source:HGNC Symbol;Acc:HGNC:20310] | 34301 | -1.488 | -0.5171 | Yes |
| 102 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34381 | -1.518 | -0.5081 | Yes |
| 103 | CARD19 | caspase recruitment domain family member 19 [Source:HGNC Symbol;Acc:HGNC:28148] | 34411 | -1.530 | -0.4977 | Yes |
| 104 | ENKD1 | enkurin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25246] | 34463 | -1.552 | -0.4878 | Yes |
| 105 | CMTM7 | CKLF like MARVEL transmembrane domain containing 7 [Source:HGNC Symbol;Acc:HGNC:19178] | 34604 | -1.606 | -0.4799 | Yes |
| 106 | SELENOH | selenoprotein H [Source:HGNC Symbol;Acc:HGNC:18251] | 34940 | -1.771 | -0.4760 | Yes |
| 107 | ABCG4 | ATP binding cassette subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:13884] | 34961 | -1.781 | -0.4635 | Yes |
| 108 | POLD2 | DNA polymerase delta 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9176] | 34987 | -1.797 | -0.4511 | Yes |
| 109 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35380 | -2.050 | -0.4467 | Yes |
| 110 | SGSM3 | small G protein signaling modulator 3 [Source:HGNC Symbol;Acc:HGNC:25228] | 35573 | -2.175 | -0.4361 | Yes |
| 111 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36255 | -2.798 | -0.4341 | Yes |
| 112 | ICA1 | islet cell autoantigen 1 [Source:HGNC Symbol;Acc:HGNC:5343] | 36280 | -2.827 | -0.4141 | Yes |
| 113 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36367 | -2.940 | -0.3950 | Yes |
| 114 | SEMA6B | semaphorin 6B [Source:HGNC Symbol;Acc:HGNC:10739] | 36370 | -2.943 | -0.3735 | Yes |
| 115 | COQ8A | coenzyme Q8A [Source:HGNC Symbol;Acc:HGNC:16812] | 36427 | -3.018 | -0.3530 | Yes |
| 116 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36476 | -3.083 | -0.3318 | Yes |
| 117 | TRAF4 | TNF receptor associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034] | 36603 | -3.267 | -0.3114 | Yes |
| 118 | FADS2 | fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575] | 36612 | -3.282 | -0.2876 | Yes |
| 119 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36625 | -3.312 | -0.2638 | Yes |
| 120 | PIMREG | PICALM interacting mitotic regulator [Source:HGNC Symbol;Acc:HGNC:25483] | 36650 | -3.347 | -0.2400 | Yes |
| 121 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36654 | -3.353 | -0.2156 | Yes |
| 122 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36698 | -3.424 | -0.1918 | Yes |
| 123 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36700 | -3.426 | -0.1668 | Yes |
| 124 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36873 | -3.821 | -0.1436 | Yes |
| 125 | SLC43A3 | solute carrier family 43 member 3 [Source:HGNC Symbol;Acc:HGNC:17466] | 36880 | -3.841 | -0.1157 | Yes |
| 126 | SNTA1 | syntrophin alpha 1 [Source:HGNC Symbol;Acc:HGNC:11167] | 36916 | -3.932 | -0.0880 | Yes |
| 127 | ZBTB12 | zinc finger and BTB domain containing 12 [Source:HGNC Symbol;Acc:HGNC:19066] | 36918 | -3.940 | -0.0592 | Yes |
| 128 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813] | 36963 | -4.078 | -0.0306 | Yes |
| 129 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37070 | -4.666 | 0.0005 | Yes |
