Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | DESCARTES_FETAL_HEART_LYMPHOID_CELLS |
| Enrichment Score (ES) | 0.6566547 |
| Normalized Enrichment Score (NES) | 1.6947181 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.031523842 |
| FWER p-Value | 0.118 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 18 | 4.849 | 0.1479 | Yes |
| 2 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 51 | 4.480 | 0.2842 | Yes |
| 3 | GVINP1 | GTPase, very large interferon inducible pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:25813] | 102 | 4.033 | 0.4063 | Yes |
| 4 | IL18RAP | interleukin 18 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5989] | 356 | 2.733 | 0.4832 | Yes |
| 5 | PDCD1 | programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760] | 448 | 2.477 | 0.5565 | Yes |
| 6 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 586 | 2.157 | 0.6188 | Yes |
| 7 | LTA | lymphotoxin alpha [Source:HGNC Symbol;Acc:HGNC:6709] | 988 | 1.590 | 0.6567 | Yes |
| 8 | TNIP3 | TNFAIP3 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:19315] | 2586 | 0.716 | 0.6354 | No |
| 9 | PAX5 | paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619] | 3091 | 0.580 | 0.6395 | No |
| 10 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 5139 | 0.162 | 0.5891 | No |
| 11 | LY9 | lymphocyte antigen 9 [Source:HGNC Symbol;Acc:HGNC:6730] | 5461 | 0.100 | 0.5835 | No |
| 12 | FCRL2 | Fc receptor like 2 [Source:HGNC Symbol;Acc:HGNC:14875] | 5740 | 0.046 | 0.5774 | No |
| 13 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 6807 | 0.000 | 0.5486 | No |
| 14 | CD160 | CD160 molecule [Source:HGNC Symbol;Acc:HGNC:17013] | 7384 | 0.000 | 0.5330 | No |
| 15 | FCMR | Fc fragment of IgM receptor [Source:HGNC Symbol;Acc:HGNC:14315] | 8048 | 0.000 | 0.5151 | No |
| 16 | GPA33 | glycoprotein A33 [Source:HGNC Symbol;Acc:HGNC:4445] | 8157 | 0.000 | 0.5122 | No |
| 17 | LINC01222 | long intergenic non-protein coding RNA 1222 [Source:HGNC Symbol;Acc:HGNC:49672] | 8171 | 0.000 | 0.5118 | No |
| 18 | LINC01215 | long intergenic non-protein coding RNA 1215 [Source:HGNC Symbol;Acc:HGNC:49651] | 8193 | 0.000 | 0.5112 | No |
| 19 | TNFRSF13B | TNF receptor superfamily member 13B [Source:HGNC Symbol;Acc:HGNC:18153] | 10160 | 0.000 | 0.4581 | No |
| 20 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 10788 | 0.000 | 0.4411 | No |
| 21 | NKG7 | natural killer cell granule protein 7 [Source:HGNC Symbol;Acc:HGNC:7830] | 11002 | 0.000 | 0.4354 | No |
| 22 | PRF1 | perforin 1 [Source:HGNC Symbol;Acc:HGNC:9360] | 11203 | 0.000 | 0.4300 | No |
| 23 | GZMA | granzyme A [Source:HGNC Symbol;Acc:HGNC:4708] | 11885 | 0.000 | 0.4115 | No |
| 24 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 11887 | 0.000 | 0.4115 | No |
| 25 | GZMH | granzyme H [Source:HGNC Symbol;Acc:HGNC:4710] | 11888 | 0.000 | 0.4115 | No |
| 26 | GZMK | granzyme K [Source:HGNC Symbol;Acc:HGNC:4711] | 11889 | 0.000 | 0.4115 | No |
| 27 | GZMM | granzyme M [Source:HGNC Symbol;Acc:HGNC:4712] | 11890 | 0.000 | 0.4115 | No |
| 28 | LINC00861 | long intergenic non-protein coding RNA 861 [Source:HGNC Symbol;Acc:HGNC:45133] | 12164 | 0.000 | 0.4041 | No |
| 29 | TNFSF11 | TNF superfamily member 11 [Source:HGNC Symbol;Acc:HGNC:11926] | 12275 | 0.000 | 0.4012 | No |
| 30 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12340 | 0.000 | 0.3994 | No |
| 31 | CDKN2A | cyclin dependent kinase inhibitor 2A [Source:HGNC Symbol;Acc:HGNC:1787] | 12481 | 0.000 | 0.3956 | No |
| 32 | UBASH3A | ubiquitin associated and SH3 domain containing A [Source:HGNC Symbol;Acc:HGNC:12462] | 12684 | 0.000 | 0.3902 | No |
| 33 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 12913 | 0.000 | 0.3840 | No |
| 34 | SAMD3 | sterile alpha motif domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21574] | 13411 | 0.000 | 0.3706 | No |
| 35 | LINC02325 | long intergenic non-protein coding RNA 2325 [Source:HGNC Symbol;Acc:HGNC:53245] | 13504 | 0.000 | 0.3681 | No |
| 36 | FLT3LG | fms related receptor tyrosine kinase 3 ligand [Source:HGNC Symbol;Acc:HGNC:3766] | 14010 | 0.000 | 0.3544 | No |
| 37 | SHISAL2A | shisa like 2A [Source:HGNC Symbol;Acc:HGNC:28757] | 14481 | 0.000 | 0.3417 | No |
| 38 | LINC02481 | long intergenic non-protein coding RNA 2481 [Source:HGNC Symbol;Acc:HGNC:27958] | 14490 | 0.000 | 0.3415 | No |
| 39 | LINC02397 | long intergenic non-protein coding RNA 2397 [Source:HGNC Symbol;Acc:HGNC:53323] | 14819 | 0.000 | 0.3326 | No |
| 40 | BLK | BLK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:1057] | 15503 | 0.000 | 0.3142 | No |
| 41 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15551 | 0.000 | 0.3129 | No |
| 42 | TBX21 | T-box transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11599] | 15666 | 0.000 | 0.3098 | No |
| 43 | CD7 | CD7 molecule [Source:HGNC Symbol;Acc:HGNC:1695] | 15679 | 0.000 | 0.3095 | No |
| 44 | CR2 | complement C3d receptor 2 [Source:HGNC Symbol;Acc:HGNC:2336] | 15781 | 0.000 | 0.3068 | No |
| 45 | XCL1 | X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645] | 15790 | 0.000 | 0.3065 | No |
| 46 | SH2D1A | SH2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:10820] | 15836 | 0.000 | 0.3053 | No |
| 47 | SH2D1B | SH2 domain containing 1B [Source:HGNC Symbol;Acc:HGNC:30416] | 15837 | 0.000 | 0.3053 | No |
| 48 | ZAP70 | zeta chain of T cell receptor associated protein kinase 70 [Source:HGNC Symbol;Acc:HGNC:12858] | 15954 | 0.000 | 0.3022 | No |
| 49 | GPR171 | G protein-coupled receptor 171 [Source:HGNC Symbol;Acc:HGNC:30057] | 16278 | 0.000 | 0.2935 | No |
| 50 | SIRPG | signal regulatory protein gamma [Source:HGNC Symbol;Acc:HGNC:15757] | 16586 | 0.000 | 0.2852 | No |
| 51 | ITK | IL2 inducible T cell kinase [Source:HGNC Symbol;Acc:HGNC:6171] | 17723 | 0.000 | 0.2544 | No |
| 52 | PTPRCAP | protein tyrosine phosphatase receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667] | 18125 | 0.000 | 0.2436 | No |
| 53 | IKZF3 | IKAROS family zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:13178] | 18188 | 0.000 | 0.2419 | No |
| 54 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18373 | 0.000 | 0.2369 | No |
| 55 | CXCR6 | C-X-C motif chemokine receptor 6 [Source:HGNC Symbol;Acc:HGNC:16647] | 19280 | 0.000 | 0.2124 | No |
| 56 | LINC01891 | long intergenic non-protein coding RNA 1891 [Source:HGNC Symbol;Acc:HGNC:52710] | 19459 | 0.000 | 0.2076 | No |
| 57 | TCF7 | transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639] | 19734 | 0.000 | 0.2002 | No |
| 58 | CHI3L2 | chitinase 3 like 2 [Source:HGNC Symbol;Acc:HGNC:1933] | 19770 | 0.000 | 0.1993 | No |
| 59 | SCML4 | Scm polycomb group protein like 4 [Source:HGNC Symbol;Acc:HGNC:21397] | 20246 | 0.000 | 0.1864 | No |
| 60 | LINC01934 | long intergenic non-protein coding RNA 1934 [Source:HGNC Symbol;Acc:HGNC:52757] | 20462 | 0.000 | 0.1806 | No |
| 61 | IFNG-AS1 | IFNG antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:43910] | 21227 | 0.000 | 0.1600 | No |
| 62 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22346 | 0.000 | 0.1297 | No |
| 63 | CD19 | CD19 molecule [Source:HGNC Symbol;Acc:HGNC:1633] | 22893 | 0.000 | 0.1150 | No |
| 64 | SLAMF6 | SLAM family member 6 [Source:HGNC Symbol;Acc:HGNC:21392] | 22897 | 0.000 | 0.1149 | No |
| 65 | SLAMF1 | signaling lymphocytic activation molecule family member 1 [Source:HGNC Symbol;Acc:HGNC:10903] | 22899 | 0.000 | 0.1149 | No |
| 66 | CD27 | CD27 molecule [Source:HGNC Symbol;Acc:HGNC:11922] | 22910 | 0.000 | 0.1146 | No |
| 67 | CD3G | CD3g molecule [Source:HGNC Symbol;Acc:HGNC:1675] | 22917 | 0.000 | 0.1144 | No |
| 68 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 22921 | 0.000 | 0.1143 | No |
| 69 | CCR7 | C-C motif chemokine receptor 7 [Source:HGNC Symbol;Acc:HGNC:1608] | 22927 | 0.000 | 0.1142 | No |
| 70 | CD52 | CD52 molecule [Source:HGNC Symbol;Acc:HGNC:1804] | 22933 | 0.000 | 0.1141 | No |
| 71 | NCR1 | natural cytotoxicity triggering receptor 1 [Source:HGNC Symbol;Acc:HGNC:6731] | 22946 | 0.000 | 0.1137 | No |
| 72 | NCR3 | natural cytotoxicity triggering receptor 3 [Source:HGNC Symbol;Acc:HGNC:19077] | 22948 | 0.000 | 0.1137 | No |
| 73 | CD96 | CD96 molecule [Source:HGNC Symbol;Acc:HGNC:16892] | 23015 | 0.000 | 0.1119 | No |
| 74 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 23018 | 0.000 | 0.1119 | No |
| 75 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 23246 | 0.000 | 0.1057 | No |
| 76 | FOXP3 | forkhead box P3 [Source:HGNC Symbol;Acc:HGNC:6106] | 23324 | 0.000 | 0.1037 | No |
| 77 | THEMIS | thymocyte selection associated [Source:HGNC Symbol;Acc:HGNC:21569] | 23533 | 0.000 | 0.0980 | No |
| 78 | KLRF1 | killer cell lectin like receptor F1 [Source:HGNC Symbol;Acc:HGNC:13342] | 23793 | 0.000 | 0.0910 | No |
| 79 | KLRB1 | killer cell lectin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6373] | 23798 | 0.000 | 0.0909 | No |
| 80 | KLRC1 | killer cell lectin like receptor C1 [Source:HGNC Symbol;Acc:HGNC:6374] | 23810 | 0.000 | 0.0906 | No |
| 81 | KLRC2 | killer cell lectin like receptor C2 [Source:HGNC Symbol;Acc:HGNC:6375] | 23811 | 0.000 | 0.0906 | No |
| 82 | SKAP1 | src kinase associated phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15605] | 23882 | 0.000 | 0.0887 | No |
| 83 | CRTAM | cytotoxic and regulatory T cell molecule [Source:HGNC Symbol;Acc:HGNC:24313] | 24215 | 0.000 | 0.0798 | No |
| 84 | LINC00426 | long intergenic non-protein coding RNA 426 [Source:HGNC Symbol;Acc:HGNC:42761] | 24344 | 0.000 | 0.0763 | No |
| 85 | CD79B | CD79b molecule [Source:HGNC Symbol;Acc:HGNC:1699] | 25389 | 0.000 | 0.0481 | No |
| 86 | KLRC4-KLRK1 | KLRC4-KLRK1 readthrough [Source:HGNC Symbol;Acc:HGNC:48357] | 25836 | 0.000 | 0.0360 | No |
| 87 | LEF1-AS1 | LEF1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40339] | 25850 | 0.000 | 0.0357 | No |
| 88 | POU2AF1 | POU class 2 homeobox associating factor 1 [Source:HGNC Symbol;Acc:HGNC:9211] | 26312 | 0.000 | 0.0232 | No |
| 89 | VPREB3 | V-set pre-B cell surrogate light chain 3 [Source:HGNC Symbol;Acc:HGNC:12710] | 26667 | 0.000 | 0.0136 | No |
| 90 | VPREB1 | V-set pre-B cell surrogate light chain 1 [Source:HGNC Symbol;Acc:HGNC:12709] | 26668 | 0.000 | 0.0136 | No |
| 91 | TRBC2 | T cell receptor beta constant 2 [Source:HGNC Symbol;Acc:HGNC:12157] | 26670 | 0.000 | 0.0136 | No |
| 92 | TMIGD2 | transmembrane and immunoglobulin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28324] | 26944 | 0.000 | 0.0062 | No |
| 93 | TIGIT | T cell immunoreceptor with Ig and ITIM domains [Source:HGNC Symbol;Acc:HGNC:26838] | 27194 | 0.000 | -0.0005 | No |
| 94 | JCHAIN | joining chain of multimeric IgA and IgM [Source:HGNC Symbol;Acc:HGNC:5713] | 27299 | 0.000 | -0.0033 | No |
| 95 | TRAT1 | T cell receptor associated transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:30698] | 27361 | 0.000 | -0.0050 | No |
| 96 | FCRL5 | Fc receptor like 5 [Source:HGNC Symbol;Acc:HGNC:18508] | 27461 | -0.017 | -0.0072 | No |
| 97 | RASGRP1 | RAS guanyl releasing protein 1 [Source:HGNC Symbol;Acc:HGNC:9878] | 28034 | -0.108 | -0.0193 | No |
| 98 | RAB25 | RAB25, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18238] | 28355 | -0.158 | -0.0232 | No |
| 99 | MEAK7 | MTOR associated protein, eak-7 homolog [Source:HGNC Symbol;Acc:HGNC:29325] | 28393 | -0.163 | -0.0192 | No |
| 100 | FCRL1 | Fc receptor like 1 [Source:HGNC Symbol;Acc:HGNC:18509] | 28460 | -0.172 | -0.0157 | No |
| 101 | SIT1 | signaling threshold regulating transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:17710] | 29370 | -0.307 | -0.0309 | No |
| 102 | ICOS | inducible T cell costimulator [Source:HGNC Symbol;Acc:HGNC:5351] | 29748 | -0.362 | -0.0300 | No |
| 103 | FCRLA | Fc receptor like A [Source:HGNC Symbol;Acc:HGNC:18504] | 30259 | -0.439 | -0.0303 | No |
| 104 | ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 [Source:HGNC Symbol;Acc:HGNC:16467] | 30362 | -0.455 | -0.0191 | No |
| 105 | FCRL3 | Fc receptor like 3 [Source:HGNC Symbol;Acc:HGNC:18506] | 31760 | -0.702 | -0.0355 | No |
| 106 | CST7 | cystatin F [Source:HGNC Symbol;Acc:HGNC:2479] | 32213 | -0.813 | -0.0228 | No |
| 107 | CXCR3 | C-X-C motif chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:4540] | 32259 | -0.828 | 0.0014 | No |
| 108 | MATK | megakaryocyte-associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6906] | 32908 | -1.009 | 0.0147 | No |
| 109 | CARD11 | caspase recruitment domain family member 11 [Source:HGNC Symbol;Acc:HGNC:16393] | 36565 | -3.213 | 0.0142 | No |
