Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | DURANTE_ADULT_OLFACTORY_NEUROEPITHELIUM_DENDRITIC_CELLS |
| Enrichment Score (ES) | 0.70779425 |
| Normalized Enrichment Score (NES) | 1.8827832 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0032443209 |
| FWER p-Value | 0.004 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.994 | 0.0311 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 4 | 4.965 | 0.0620 | Yes |
| 3 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 23 | 4.787 | 0.0914 | Yes |
| 4 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 39 | 4.636 | 0.1199 | Yes |
| 5 | OSM | oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506] | 42 | 4.572 | 0.1484 | Yes |
| 6 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 64 | 4.377 | 0.1751 | Yes |
| 7 | NLRP3 | NLR family pyrin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:16400] | 113 | 3.965 | 0.1986 | Yes |
| 8 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 131 | 3.894 | 0.2224 | Yes |
| 9 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 151 | 3.729 | 0.2451 | Yes |
| 10 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 159 | 3.663 | 0.2678 | Yes |
| 11 | CLEC4E | C-type lectin domain family 4 member E [Source:HGNC Symbol;Acc:HGNC:14555] | 203 | 3.411 | 0.2879 | Yes |
| 12 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 216 | 3.338 | 0.3084 | Yes |
| 13 | C5AR1 | complement C5a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1338] | 232 | 3.252 | 0.3283 | Yes |
| 14 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 241 | 3.211 | 0.3481 | Yes |
| 15 | FGR | FGR proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3697] | 246 | 3.196 | 0.3679 | Yes |
| 16 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 251 | 3.171 | 0.3876 | Yes |
| 17 | SRGN | serglycin [Source:HGNC Symbol;Acc:HGNC:9361] | 264 | 3.120 | 0.4067 | Yes |
| 18 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 269 | 3.083 | 0.4259 | Yes |
| 19 | CD36 | CD36 molecule [Source:HGNC Symbol;Acc:HGNC:1663] | 277 | 3.030 | 0.4446 | Yes |
| 20 | PLEK | pleckstrin [Source:HGNC Symbol;Acc:HGNC:9070] | 286 | 3.006 | 0.4631 | Yes |
| 21 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 300 | 2.921 | 0.4810 | Yes |
| 22 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 313 | 2.870 | 0.4986 | Yes |
| 23 | MNDA | myeloid cell nuclear differentiation antigen [Source:HGNC Symbol;Acc:HGNC:7183] | 315 | 2.865 | 0.5164 | Yes |
| 24 | LYN | LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6735] | 351 | 2.755 | 0.5326 | Yes |
| 25 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 444 | 2.489 | 0.5457 | Yes |
| 26 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 486 | 2.398 | 0.5595 | Yes |
| 27 | FYB1 | FYN binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4036] | 487 | 2.396 | 0.5745 | Yes |
| 28 | ACTB | actin beta [Source:HGNC Symbol;Acc:HGNC:132] | 524 | 2.296 | 0.5878 | Yes |
| 29 | IFITM2 | interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413] | 629 | 2.094 | 0.5981 | Yes |
| 30 | CFP | complement factor properdin [Source:HGNC Symbol;Acc:HGNC:8864] | 719 | 1.941 | 0.6078 | Yes |
| 31 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 727 | 1.931 | 0.6196 | Yes |
| 32 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 850 | 1.758 | 0.6273 | Yes |
| 33 | RNF149 | ring finger protein 149 [Source:HGNC Symbol;Acc:HGNC:23137] | 1104 | 1.465 | 0.6296 | Yes |
| 34 | FCER1G | Fc fragment of IgE receptor Ig [Source:HGNC Symbol;Acc:HGNC:3611] | 1115 | 1.453 | 0.6384 | Yes |
| 35 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 1339 | 1.287 | 0.6404 | Yes |
| 36 | FTH1 | ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976] | 1368 | 1.266 | 0.6475 | Yes |
| 37 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 1387 | 1.254 | 0.6549 | Yes |
| 38 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 1406 | 1.243 | 0.6621 | Yes |
| 39 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 1427 | 1.232 | 0.6693 | Yes |
| 40 | LCP1 | lymphocyte cytosolic protein 1 [Source:HGNC Symbol;Acc:HGNC:6528] | 1513 | 1.182 | 0.6743 | Yes |
| 41 | CYBB | cytochrome b-245 beta chain [Source:HGNC Symbol;Acc:HGNC:2578] | 1624 | 1.131 | 0.6784 | Yes |
| 42 | EVI2B | ecotropic viral integration site 2B [Source:HGNC Symbol;Acc:HGNC:3500] | 1697 | 1.093 | 0.6833 | Yes |
| 43 | SPI1 | Spi-1 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:11241] | 1798 | 1.035 | 0.6870 | Yes |
| 44 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1808 | 1.029 | 0.6932 | Yes |
| 45 | COTL1 | coactosin like F-actin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:18304] | 1929 | 0.982 | 0.6961 | Yes |
| 46 | ITGB2 | integrin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6155] | 1973 | 0.957 | 0.7009 | Yes |
| 47 | MPEG1 | macrophage expressed 1 [Source:HGNC Symbol;Acc:HGNC:29619] | 2004 | 0.941 | 0.7060 | Yes |
| 48 | GCA | grancalcin [Source:HGNC Symbol;Acc:HGNC:15990] | 2140 | 0.880 | 0.7078 | Yes |
| 49 | MXD1 | MAX dimerization protein 1 [Source:HGNC Symbol;Acc:HGNC:6761] | 2353 | 0.796 | 0.7070 | No |
| 50 | CORO1A | coronin 1A [Source:HGNC Symbol;Acc:HGNC:2252] | 3204 | 0.551 | 0.6875 | No |
| 51 | CPVL | carboxypeptidase vitellogenic like [Source:HGNC Symbol;Acc:HGNC:14399] | 3230 | 0.545 | 0.6902 | No |
| 52 | NCF2 | neutrophil cytosolic factor 2 [Source:HGNC Symbol;Acc:HGNC:7661] | 3250 | 0.538 | 0.6930 | No |
| 53 | ZEB2 | zinc finger E-box binding homeobox 2 [Source:HGNC Symbol;Acc:HGNC:14881] | 3436 | 0.499 | 0.6912 | No |
| 54 | CTSS | cathepsin S [Source:HGNC Symbol;Acc:HGNC:2545] | 4042 | 0.369 | 0.6771 | No |
| 55 | PTPRC | protein tyrosine phosphatase receptor type C [Source:HGNC Symbol;Acc:HGNC:9666] | 4808 | 0.217 | 0.6578 | No |
| 56 | CYBA | cytochrome b-245 alpha chain [Source:HGNC Symbol;Acc:HGNC:2577] | 5270 | 0.136 | 0.6461 | No |
| 57 | OAZ1 | ornithine decarboxylase antizyme 1 [Source:HGNC Symbol;Acc:HGNC:8095] | 5296 | 0.131 | 0.6463 | No |
| 58 | LST1 | leukocyte specific transcript 1 [Source:HGNC Symbol;Acc:HGNC:14189] | 7461 | 0.000 | 0.5878 | No |
| 59 | FCN1 | ficolin 1 [Source:HGNC Symbol;Acc:HGNC:3623] | 8046 | 0.000 | 0.5720 | No |
| 60 | S100A9 | S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499] | 8188 | 0.000 | 0.5681 | No |
| 61 | S100A8 | S100 calcium binding protein A8 [Source:HGNC Symbol;Acc:HGNC:10498] | 8191 | 0.000 | 0.5681 | No |
| 62 | PYCARD | PYD and CARD domain containing [Source:HGNC Symbol;Acc:HGNC:16608] | 8525 | 0.000 | 0.5591 | No |
| 63 | CLEC7A | C-type lectin domain containing 7A [Source:HGNC Symbol;Acc:HGNC:14558] | 9186 | 0.000 | 0.5412 | No |
| 64 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 9645 | 0.000 | 0.5288 | No |
| 65 | C1orf162 | chromosome 1 open reading frame 162 [Source:HGNC Symbol;Acc:HGNC:28344] | 9830 | 0.000 | 0.5239 | No |
| 66 | TYMP | thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148] | 9932 | 0.000 | 0.5211 | No |
| 67 | MS4A7 | membrane spanning 4-domains A7 [Source:HGNC Symbol;Acc:HGNC:13378] | 10771 | 0.000 | 0.4985 | No |
| 68 | FCGR3A | Fc fragment of IgG receptor IIIa [Source:HGNC Symbol;Acc:HGNC:3619] | 11160 | 0.000 | 0.4880 | No |
| 69 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11204 | 0.000 | 0.4868 | No |
| 70 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11211 | 0.000 | 0.4867 | No |
| 71 | S100A12 | S100 calcium binding protein A12 [Source:HGNC Symbol;Acc:HGNC:10489] | 11409 | 0.000 | 0.4813 | No |
| 72 | JAML | junction adhesion molecule like [Source:HGNC Symbol;Acc:HGNC:19084] | 11834 | 0.000 | 0.4699 | No |
| 73 | APOBEC3A | apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343] | 12312 | 0.000 | 0.4570 | No |
| 74 | LILRB2 | leukocyte immunoglobulin like receptor B2 [Source:HGNC Symbol;Acc:HGNC:6606] | 13281 | 0.000 | 0.4308 | No |
| 75 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14584 | 0.000 | 0.3956 | No |
| 76 | LGALS2 | galectin 2 [Source:HGNC Symbol;Acc:HGNC:6562] | 15558 | 0.000 | 0.3692 | No |
| 77 | CFD | complement factor D [Source:HGNC Symbol;Acc:HGNC:2771] | 15701 | 0.000 | 0.3654 | No |
| 78 | CLEC12A | C-type lectin domain family 12 member A [Source:HGNC Symbol;Acc:HGNC:31713] | 15965 | 0.000 | 0.3583 | No |
| 79 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16139 | 0.000 | 0.3536 | No |
| 80 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16438 | 0.000 | 0.3456 | No |
| 81 | SERPINA1 | serpin family A member 1 [Source:HGNC Symbol;Acc:HGNC:8941] | 17724 | 0.000 | 0.3108 | No |
| 82 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19371 | 0.000 | 0.2663 | No |
| 83 | RIPOR2 | RHO family interacting cell polarization regulator 2 [Source:HGNC Symbol;Acc:HGNC:13872] | 20066 | 0.000 | 0.2475 | No |
| 84 | CD52 | CD52 molecule [Source:HGNC Symbol;Acc:HGNC:1804] | 22933 | 0.000 | 0.1700 | No |
| 85 | CD48 | CD48 molecule [Source:HGNC Symbol;Acc:HGNC:1683] | 22950 | 0.000 | 0.1696 | No |
| 86 | PILRA | paired immunoglobin like type 2 receptor alpha [Source:HGNC Symbol;Acc:HGNC:20396] | 23477 | 0.000 | 0.1553 | No |
| 87 | PELATON | plaque enriched lncRNA in atherosclerotic and inflammatory bowel macrophage regulation [Source:HGNC Symbol;Acc:HGNC:50328] | 24191 | 0.000 | 0.1361 | No |
| 88 | CSTA | cystatin A [Source:HGNC Symbol;Acc:HGNC:2481] | 24587 | 0.000 | 0.1254 | No |
| 89 | CST3 | cystatin C [Source:HGNC Symbol;Acc:HGNC:2475] | 24595 | 0.000 | 0.1252 | No |
| 90 | FGL2 | fibrinogen like 2 [Source:HGNC Symbol;Acc:HGNC:3696] | 25328 | 0.000 | 0.1054 | No |
| 91 | PLAUR | plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053] | 25527 | 0.000 | 0.1000 | No |
| 92 | MS4A6A | membrane spanning 4-domains A6A [Source:HGNC Symbol;Acc:HGNC:13375] | 25911 | 0.000 | 0.0897 | No |
| 93 | ATP2B1-AS1 | ATP2B1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27883] | 27935 | -0.094 | 0.0355 | No |
| 94 | VCAN | versican [Source:HGNC Symbol;Acc:HGNC:2464] | 27953 | -0.096 | 0.0357 | No |
| 95 | FTL | ferritin light chain [Source:HGNC Symbol;Acc:HGNC:3999] | 29143 | -0.271 | 0.0052 | No |
| 96 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 29237 | -0.287 | 0.0045 | No |
| 97 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 29680 | -0.351 | -0.0053 | No |
| 98 | CD37 | CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666] | 31357 | -0.624 | -0.0467 | No |
| 99 | AIF1 | allograft inflammatory factor 1 [Source:HGNC Symbol;Acc:HGNC:352] | 31603 | -0.671 | -0.0492 | No |
| 100 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 31694 | -0.688 | -0.0473 | No |
| 101 | RGS2 | regulator of G protein signaling 2 [Source:HGNC Symbol;Acc:HGNC:9998] | 32048 | -0.767 | -0.0521 | No |
| 102 | NCF1 | neutrophil cytosolic factor 1 [Source:HGNC Symbol;Acc:HGNC:7660] | 33172 | -1.087 | -0.0757 | No |
| 103 | TNFSF13B | TNF superfamily member 13b [Source:HGNC Symbol;Acc:HGNC:11929] | 33289 | -1.126 | -0.0718 | No |
| 104 | PHACTR1 | phosphatase and actin regulator 1 [Source:HGNC Symbol;Acc:HGNC:20990] | 33699 | -1.264 | -0.0749 | No |
| 105 | GMFG | glia maturation factor gamma [Source:HGNC Symbol;Acc:HGNC:4374] | 33936 | -1.348 | -0.0729 | No |
| 106 | SH3BGRL3 | SH3 domain binding glutamate rich protein like 3 [Source:HGNC Symbol;Acc:HGNC:15568] | 34300 | -1.487 | -0.0735 | No |
| 107 | TYROBP | transmembrane immune signaling adaptor TYROBP [Source:HGNC Symbol;Acc:HGNC:12449] | 34546 | -1.577 | -0.0702 | No |
| 108 | STXBP2 | syntaxin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:11445] | 34726 | -1.662 | -0.0647 | No |
| 109 | IGSF6 | immunoglobulin superfamily member 6 [Source:HGNC Symbol;Acc:HGNC:5953] | 34797 | -1.698 | -0.0560 | No |
| 110 | TKT | transketolase [Source:HGNC Symbol;Acc:HGNC:11834] | 34826 | -1.709 | -0.0461 | No |
| 111 | AP1S2 | adaptor related protein complex 1 subunit sigma 2 [Source:HGNC Symbol;Acc:HGNC:560] | 34976 | -1.789 | -0.0390 | No |
| 112 | CD68 | CD68 molecule [Source:HGNC Symbol;Acc:HGNC:1693] | 35017 | -1.813 | -0.0288 | No |
| 113 | LSP1 | lymphocyte specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707] | 35044 | -1.831 | -0.0180 | No |
| 114 | LAPTM5 | lysosomal protein transmembrane 5 [Source:HGNC Symbol;Acc:HGNC:29612] | 36018 | -2.568 | -0.0283 | No |
| 115 | CSF3R | colony stimulating factor 3 receptor [Source:HGNC Symbol;Acc:HGNC:2439] | 36194 | -2.747 | -0.0159 | No |
| 116 | PSAP | prosaposin [Source:HGNC Symbol;Acc:HGNC:9498] | 36449 | -3.048 | -0.0038 | No |
| 117 | NEAT1 | nuclear paraspeckle assembly transcript 1 [Source:HGNC Symbol;Acc:HGNC:30815] | 36668 | -3.383 | 0.0114 | No |
