Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | DURANTE_ADULT_OLFACTORY_NEUROEPITHELIUM_NK_CELLS |
| Enrichment Score (ES) | 0.64260674 |
| Normalized Enrichment Score (NES) | 1.5818303 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.077037975 |
| FWER p-Value | 0.368 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 26 | 4.768 | 0.0612 | Yes |
| 2 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 30 | 4.738 | 0.1226 | Yes |
| 3 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 127 | 3.902 | 0.1707 | Yes |
| 4 | EVL | Enah/Vasp-like [Source:HGNC Symbol;Acc:HGNC:20234] | 167 | 3.630 | 0.2167 | Yes |
| 5 | SRGN | serglycin [Source:HGNC Symbol;Acc:HGNC:9361] | 264 | 3.120 | 0.2546 | Yes |
| 6 | PLEK | pleckstrin [Source:HGNC Symbol;Acc:HGNC:9070] | 286 | 3.006 | 0.2931 | Yes |
| 7 | RAP1B | RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857] | 359 | 2.730 | 0.3266 | Yes |
| 8 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 589 | 2.154 | 0.3484 | Yes |
| 9 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 595 | 2.141 | 0.3760 | Yes |
| 10 | IFITM2 | interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413] | 629 | 2.094 | 0.4023 | Yes |
| 11 | PSMB9 | proteasome 20S subunit beta 9 [Source:HGNC Symbol;Acc:HGNC:9546] | 764 | 1.869 | 0.4229 | Yes |
| 12 | EFHD2 | EF-hand domain family member D2 [Source:HGNC Symbol;Acc:HGNC:28670] | 786 | 1.840 | 0.4463 | Yes |
| 13 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 850 | 1.758 | 0.4674 | Yes |
| 14 | MYL12A | myosin light chain 12A [Source:HGNC Symbol;Acc:HGNC:16701] | 1006 | 1.570 | 0.4836 | Yes |
| 15 | RAC2 | Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802] | 1044 | 1.526 | 0.5024 | Yes |
| 16 | HLA-B | major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:HGNC:4932] | 1095 | 1.472 | 0.5201 | Yes |
| 17 | PFN1 | profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881] | 1099 | 1.468 | 0.5391 | Yes |
| 18 | FCER1G | Fc fragment of IgE receptor Ig [Source:HGNC Symbol;Acc:HGNC:3611] | 1115 | 1.453 | 0.5576 | Yes |
| 19 | CD53 | CD53 molecule [Source:HGNC Symbol;Acc:HGNC:1686] | 1222 | 1.375 | 0.5726 | Yes |
| 20 | DOK2 | docking protein 2 [Source:HGNC Symbol;Acc:HGNC:2991] | 1257 | 1.345 | 0.5891 | Yes |
| 21 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 1464 | 1.209 | 0.5992 | Yes |
| 22 | HOPX | HOP homeobox [Source:HGNC Symbol;Acc:HGNC:24961] | 1475 | 1.204 | 0.6146 | Yes |
| 23 | LCP1 | lymphocyte cytosolic protein 1 [Source:HGNC Symbol;Acc:HGNC:6528] | 1513 | 1.182 | 0.6289 | Yes |
| 24 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 1772 | 1.050 | 0.6356 | Yes |
| 25 | ITGB2 | integrin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6155] | 1973 | 0.957 | 0.6426 | Yes |
| 26 | CORO1A | coronin 1A [Source:HGNC Symbol;Acc:HGNC:2252] | 3204 | 0.551 | 0.6165 | No |
| 27 | CD247 | CD247 molecule [Source:HGNC Symbol;Acc:HGNC:1677] | 3667 | 0.446 | 0.6098 | No |
| 28 | CYRIB | CYFIP related Rac1 interactor B [Source:HGNC Symbol;Acc:HGNC:25216] | 4301 | 0.318 | 0.5968 | No |
| 29 | B2M | beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914] | 4631 | 0.246 | 0.5912 | No |
| 30 | PTPRC | protein tyrosine phosphatase receptor type C [Source:HGNC Symbol;Acc:HGNC:9666] | 4808 | 0.217 | 0.5892 | No |
| 31 | TMSB4X | thymosin beta 4 X-linked [Source:HGNC Symbol;Acc:HGNC:11881] | 4826 | 0.214 | 0.5915 | No |
| 32 | CYBA | cytochrome b-245 alpha chain [Source:HGNC Symbol;Acc:HGNC:2577] | 5270 | 0.136 | 0.5813 | No |
| 33 | CD160 | CD160 molecule [Source:HGNC Symbol;Acc:HGNC:17013] | 7384 | 0.000 | 0.5242 | No |
| 34 | CLIC3 | chloride intracellular channel 3 [Source:HGNC Symbol;Acc:HGNC:2064] | 7491 | 0.000 | 0.5214 | No |
| 35 | NKG7 | natural killer cell granule protein 7 [Source:HGNC Symbol;Acc:HGNC:7830] | 11002 | 0.000 | 0.4265 | No |
| 36 | FCGR3A | Fc fragment of IgG receptor IIIa [Source:HGNC Symbol;Acc:HGNC:3619] | 11160 | 0.000 | 0.4223 | No |
| 37 | PRF1 | perforin 1 [Source:HGNC Symbol;Acc:HGNC:9360] | 11203 | 0.000 | 0.4212 | No |
| 38 | PTGDS | prostaglandin D2 synthase [Source:HGNC Symbol;Acc:HGNC:9592] | 11536 | 0.000 | 0.4122 | No |
| 39 | GZMA | granzyme A [Source:HGNC Symbol;Acc:HGNC:4708] | 11885 | 0.000 | 0.4028 | No |
| 40 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 11887 | 0.000 | 0.4028 | No |
| 41 | GZMH | granzyme H [Source:HGNC Symbol;Acc:HGNC:4710] | 11888 | 0.000 | 0.4028 | No |
| 42 | GZMM | granzyme M [Source:HGNC Symbol;Acc:HGNC:4712] | 11890 | 0.000 | 0.4027 | No |
| 43 | SPN | sialophorin [Source:HGNC Symbol;Acc:HGNC:11249] | 12230 | 0.000 | 0.3936 | No |
| 44 | APOBEC3G | apolipoprotein B mRNA editing enzyme catalytic subunit 3G [Source:HGNC Symbol;Acc:HGNC:17357] | 12300 | 0.000 | 0.3917 | No |
| 45 | IL32 | interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830] | 13666 | 0.000 | 0.3548 | No |
| 46 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15551 | 0.000 | 0.3039 | No |
| 47 | CD7 | CD7 molecule [Source:HGNC Symbol;Acc:HGNC:1695] | 15679 | 0.000 | 0.3005 | No |
| 48 | XCL2 | X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10646] | 15788 | 0.000 | 0.2976 | No |
| 49 | SPON2 | spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253] | 18883 | 0.000 | 0.2140 | No |
| 50 | PYHIN1 | pyrin and HIN domain family member 1 [Source:HGNC Symbol;Acc:HGNC:28894] | 20613 | 0.000 | 0.1672 | No |
| 51 | TRDC | T cell receptor delta constant [Source:HGNC Symbol;Acc:HGNC:12253] | 21503 | 0.000 | 0.1432 | No |
| 52 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22346 | 0.000 | 0.1205 | No |
| 53 | CD52 | CD52 molecule [Source:HGNC Symbol;Acc:HGNC:1804] | 22933 | 0.000 | 0.1046 | No |
| 54 | CD48 | CD48 molecule [Source:HGNC Symbol;Acc:HGNC:1683] | 22950 | 0.000 | 0.1042 | No |
| 55 | CD69 | CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694] | 23006 | 0.000 | 0.1027 | No |
| 56 | KLRF1 | killer cell lectin like receptor F1 [Source:HGNC Symbol;Acc:HGNC:13342] | 23793 | 0.000 | 0.0815 | No |
| 57 | KLRB1 | killer cell lectin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6373] | 23798 | 0.000 | 0.0814 | No |
| 58 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 23816 | 0.000 | 0.0809 | No |
| 59 | CTSW | cathepsin W [Source:HGNC Symbol;Acc:HGNC:2546] | 24937 | 0.000 | 0.0506 | No |
| 60 | PLAAT4 | phospholipase A and acyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:9869] | 24958 | 0.000 | 0.0501 | No |
| 61 | MYOM2 | myomesin 2 [Source:HGNC Symbol;Acc:HGNC:7614] | 25131 | 0.000 | 0.0454 | No |
| 62 | PLAC8 | placenta associated 8 [Source:HGNC Symbol;Acc:HGNC:19254] | 25211 | 0.000 | 0.0433 | No |
| 63 | FGFBP2 | fibroblast growth factor binding protein 2 [Source:HGNC Symbol;Acc:HGNC:29451] | 25622 | 0.000 | 0.0322 | No |
| 64 | BIN2 | bridging integrator 2 [Source:HGNC Symbol;Acc:HGNC:1053] | 29325 | -0.300 | -0.0639 | No |
| 65 | TRAF3IP3 | TRAF3 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:30766] | 29513 | -0.329 | -0.0647 | No |
| 66 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 29680 | -0.351 | -0.0646 | No |
| 67 | TBC1D10C | TBC1 domain family member 10C [Source:HGNC Symbol;Acc:HGNC:24702] | 29808 | -0.369 | -0.0632 | No |
| 68 | HCST | hematopoietic cell signal transducer [Source:HGNC Symbol;Acc:HGNC:16977] | 30414 | -0.462 | -0.0736 | No |
| 69 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 30535 | -0.483 | -0.0706 | No |
| 70 | ARHGDIB | Rho GDP dissociation inhibitor beta [Source:HGNC Symbol;Acc:HGNC:679] | 31585 | -0.667 | -0.0902 | No |
| 71 | CST7 | cystatin F [Source:HGNC Symbol;Acc:HGNC:2479] | 32213 | -0.813 | -0.0966 | No |
| 72 | GPR65 | G protein-coupled receptor 65 [Source:HGNC Symbol;Acc:HGNC:4517] | 32526 | -0.892 | -0.0935 | No |
| 73 | ARL4C | ADP ribosylation factor like GTPase 4C [Source:HGNC Symbol;Acc:HGNC:698] | 32905 | -1.009 | -0.0906 | No |
| 74 | MATK | megakaryocyte-associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6906] | 32908 | -1.009 | -0.0776 | No |
| 75 | CXCR4 | C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561] | 33282 | -1.123 | -0.0731 | No |
| 76 | PPP2R5C | protein phosphatase 2 regulatory subunit B'gamma [Source:HGNC Symbol;Acc:HGNC:9311] | 33284 | -1.124 | -0.0585 | No |
| 77 | CCND3 | cyclin D3 [Source:HGNC Symbol;Acc:HGNC:1585] | 33387 | -1.156 | -0.0463 | No |
| 78 | UCP2 | uncoupling protein 2 [Source:HGNC Symbol;Acc:HGNC:12518] | 33931 | -1.347 | -0.0434 | No |
| 79 | SH3BGRL3 | SH3 domain binding glutamate rich protein like 3 [Source:HGNC Symbol;Acc:HGNC:15568] | 34300 | -1.487 | -0.0341 | No |
| 80 | TYROBP | transmembrane immune signaling adaptor TYROBP [Source:HGNC Symbol;Acc:HGNC:12449] | 34546 | -1.577 | -0.0202 | No |
| 81 | LSP1 | lymphocyte specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707] | 35044 | -1.831 | -0.0099 | No |
| 82 | MYO1F | myosin IF [Source:HGNC Symbol;Acc:HGNC:7600] | 35679 | -2.256 | 0.0023 | No |
| 83 | CMC1 | C-X9-C motif containing 1 [Source:HGNC Symbol;Acc:HGNC:28783] | 36210 | -2.761 | 0.0238 | No |
