Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | TRAVAGLINI_LUNG_MUCOUS_CELL |
| Enrichment Score (ES) | 0.5929276 |
| Normalized Enrichment Score (NES) | 1.5753987 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.079010874 |
| FWER p-Value | 0.385 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 0 | 4.995 | 0.0540 | Yes |
| 2 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 6 | 4.951 | 0.1074 | Yes |
| 3 | DUSP5 | dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071] | 8 | 4.941 | 0.1609 | Yes |
| 4 | CFB | complement factor B [Source:HGNC Symbol;Acc:HGNC:1037] | 24 | 4.783 | 0.2122 | Yes |
| 5 | CPD | carboxypeptidase D [Source:HGNC Symbol;Acc:HGNC:2301] | 93 | 4.085 | 0.2545 | Yes |
| 6 | ASS1 | argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758] | 122 | 3.926 | 0.2962 | Yes |
| 7 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 216 | 3.338 | 0.3298 | Yes |
| 8 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 300 | 2.921 | 0.3592 | Yes |
| 9 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 336 | 2.805 | 0.3886 | Yes |
| 10 | LYN | LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6735] | 351 | 2.755 | 0.4180 | Yes |
| 11 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 425 | 2.542 | 0.4435 | Yes |
| 12 | ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10862] | 621 | 2.117 | 0.4611 | Yes |
| 13 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 675 | 1.997 | 0.4813 | Yes |
| 14 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 731 | 1.925 | 0.5006 | Yes |
| 15 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 753 | 1.886 | 0.5204 | Yes |
| 16 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 802 | 1.811 | 0.5387 | Yes |
| 17 | REEP3 | receptor accessory protein 3 [Source:HGNC Symbol;Acc:HGNC:23711] | 1248 | 1.348 | 0.5413 | Yes |
| 18 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 1387 | 1.254 | 0.5511 | Yes |
| 19 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 1509 | 1.184 | 0.5606 | Yes |
| 20 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 1539 | 1.177 | 0.5726 | Yes |
| 21 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 1716 | 1.080 | 0.5795 | Yes |
| 22 | MED24 | mediator complex subunit 24 [Source:HGNC Symbol;Acc:HGNC:22963] | 1821 | 1.026 | 0.5878 | Yes |
| 23 | C15orf48 | chromosome 15 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:29898] | 2098 | 0.899 | 0.5901 | Yes |
| 24 | MDK | midkine [Source:HGNC Symbol;Acc:HGNC:6972] | 2443 | 0.765 | 0.5890 | Yes |
| 25 | TNIP3 | TNFAIP3 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:19315] | 2586 | 0.716 | 0.5929 | Yes |
| 26 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 2890 | 0.626 | 0.5915 | No |
| 27 | TGM2 | transglutaminase 2 [Source:HGNC Symbol;Acc:HGNC:11778] | 3099 | 0.579 | 0.5921 | No |
| 28 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 3430 | 0.500 | 0.5886 | No |
| 29 | TMEM165 | transmembrane protein 165 [Source:HGNC Symbol;Acc:HGNC:30760] | 3666 | 0.446 | 0.5871 | No |
| 30 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 3891 | 0.402 | 0.5854 | No |
| 31 | LAG3 | lymphocyte activating 3 [Source:HGNC Symbol;Acc:HGNC:6476] | 4545 | 0.268 | 0.5706 | No |
| 32 | KDR | kinase insert domain receptor [Source:HGNC Symbol;Acc:HGNC:6307] | 4846 | 0.211 | 0.5648 | No |
| 33 | XBP1 | X-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12801] | 5038 | 0.171 | 0.5615 | No |
| 34 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6046 | 0.000 | 0.5342 | No |
| 35 | MUCL1 | mucin like 1 [Source:HGNC Symbol;Acc:HGNC:30588] | 6141 | 0.000 | 0.5317 | No |
| 36 | DEFB4A | defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] | 6832 | 0.000 | 0.5130 | No |
| 37 | WFDC2 | WAP four-disulfide core domain 2 [Source:HGNC Symbol;Acc:HGNC:15939] | 7797 | 0.000 | 0.4869 | No |
| 38 | PROM1 | prominin 1 [Source:HGNC Symbol;Acc:HGNC:9454] | 7913 | 0.000 | 0.4838 | No |
| 39 | S100A9 | S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499] | 8188 | 0.000 | 0.4764 | No |
| 40 | CRISP3 | cysteine rich secretory protein 3 [Source:HGNC Symbol;Acc:HGNC:16904] | 8756 | 0.000 | 0.4611 | No |
| 41 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 8858 | 0.000 | 0.4583 | No |
| 42 | SLPI | secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092] | 8943 | 0.000 | 0.4561 | No |
| 43 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9198 | 0.000 | 0.4492 | No |
| 44 | ADAM28 | ADAM metallopeptidase domain 28 [Source:HGNC Symbol;Acc:HGNC:206] | 9432 | 0.000 | 0.4429 | No |
| 45 | CYP2F1 | cytochrome P450 family 2 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:2632] | 10078 | 0.000 | 0.4254 | No |
| 46 | KLK10 | kallikrein related peptidase 10 [Source:HGNC Symbol;Acc:HGNC:6358] | 10178 | 0.000 | 0.4228 | No |
| 47 | KLK11 | kallikrein related peptidase 11 [Source:HGNC Symbol;Acc:HGNC:6359] | 10179 | 0.000 | 0.4228 | No |
| 48 | KLK12 | kallikrein related peptidase 12 [Source:HGNC Symbol;Acc:HGNC:6360] | 10180 | 0.000 | 0.4228 | No |
| 49 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10448 | 0.000 | 0.4155 | No |
| 50 | LCN2 | lipocalin 2 [Source:HGNC Symbol;Acc:HGNC:6526] | 10637 | 0.000 | 0.4104 | No |
| 51 | SLC26A4 | solute carrier family 26 member 4 [Source:HGNC Symbol;Acc:HGNC:8818] | 10875 | 0.000 | 0.4040 | No |
| 52 | TSPAN8 | tetraspanin 8 [Source:HGNC Symbol;Acc:HGNC:11855] | 11220 | 0.000 | 0.3947 | No |
| 53 | AKR1C1 | aldo-keto reductase family 1 member C1 [Source:HGNC Symbol;Acc:HGNC:384] | 11260 | 0.000 | 0.3937 | No |
| 54 | AKR1C2 | aldo-keto reductase family 1 member C2 [Source:HGNC Symbol;Acc:HGNC:385] | 11262 | 0.000 | 0.3936 | No |
| 55 | S100P | S100 calcium binding protein P [Source:HGNC Symbol;Acc:HGNC:10504] | 11371 | 0.000 | 0.3907 | No |
| 56 | BACE2 | beta-secretase 2 [Source:HGNC Symbol;Acc:HGNC:934] | 11432 | 0.000 | 0.3891 | No |
| 57 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11483 | 0.000 | 0.3878 | No |
| 58 | MSMB | microseminoprotein beta [Source:HGNC Symbol;Acc:HGNC:7372] | 12234 | 0.000 | 0.3675 | No |
| 59 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12274 | 0.000 | 0.3664 | No |
| 60 | VMO1 | vitelline membrane outer layer 1 homolog [Source:HGNC Symbol;Acc:HGNC:30387] | 12320 | 0.000 | 0.3652 | No |
| 61 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 12636 | 0.000 | 0.3567 | No |
| 62 | MUC4 | mucin 4, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7514] | 12663 | 0.000 | 0.3560 | No |
| 63 | LINC00342 | long intergenic non-protein coding RNA 342 [Source:HGNC Symbol;Acc:HGNC:42470] | 12851 | 0.000 | 0.3509 | No |
| 64 | ZG16B | zymogen granule protein 16B [Source:HGNC Symbol;Acc:HGNC:30456] | 13124 | 0.000 | 0.3435 | No |
| 65 | TMC5 | transmembrane channel like 5 [Source:HGNC Symbol;Acc:HGNC:22999] | 14261 | 0.000 | 0.3128 | No |
| 66 | TMEM45A | transmembrane protein 45A [Source:HGNC Symbol;Acc:HGNC:25480] | 14607 | 0.000 | 0.3035 | No |
| 67 | CDC42EP5 | CDC42 effector protein 5 [Source:HGNC Symbol;Acc:HGNC:17408] | 16081 | 0.000 | 0.2636 | No |
| 68 | BPIFA1 | BPI fold containing family A member 1 [Source:HGNC Symbol;Acc:HGNC:15749] | 17524 | 0.000 | 0.2246 | No |
| 69 | BPIFB1 | BPI fold containing family B member 1 [Source:HGNC Symbol;Acc:HGNC:16108] | 17575 | 0.000 | 0.2233 | No |
| 70 | ANKRD36C | ankyrin repeat domain 36C [Source:HGNC Symbol;Acc:HGNC:32946] | 17775 | 0.000 | 0.2179 | No |
| 71 | HILPDA | hypoxia inducible lipid droplet associated [Source:HGNC Symbol;Acc:HGNC:28859] | 17823 | 0.000 | 0.2166 | No |
| 72 | HLA-DQA2 | major histocompatibility complex, class II, DQ alpha 2 [Source:HGNC Symbol;Acc:HGNC:4943] | 18323 | 0.000 | 0.2031 | No |
| 73 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18324 | 0.000 | 0.2031 | No |
| 74 | LTF | lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720] | 18665 | 0.000 | 0.1939 | No |
| 75 | MMP7 | matrix metallopeptidase 7 [Source:HGNC Symbol;Acc:HGNC:7174] | 19029 | 0.000 | 0.1841 | No |
| 76 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19366 | 0.000 | 0.1750 | No |
| 77 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19371 | 0.000 | 0.1749 | No |
| 78 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19380 | 0.000 | 0.1747 | No |
| 79 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19382 | 0.000 | 0.1747 | No |
| 80 | SMIM31 | small integral membrane protein 31 [Source:HGNC Symbol;Acc:HGNC:49638] | 19639 | 0.000 | 0.1677 | No |
| 81 | HSD17B2 | hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211] | 19703 | 0.000 | 0.1660 | No |
| 82 | PI3 | peptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:8947] | 19932 | 0.000 | 0.1599 | No |
| 83 | IDO1 | indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059] | 20113 | 0.000 | 0.1550 | No |
| 84 | TFF3 | trefoil factor 3 [Source:HGNC Symbol;Acc:HGNC:11757] | 20633 | 0.000 | 0.1410 | No |
| 85 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 21932 | 0.000 | 0.1058 | No |
| 86 | PIGR | polymeric immunoglobulin receptor [Source:HGNC Symbol;Acc:HGNC:8968] | 22682 | 0.000 | 0.0856 | No |
| 87 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22836 | 0.000 | 0.0814 | No |
| 88 | SCGB3A1 | secretoglobin family 3A member 1 [Source:HGNC Symbol;Acc:HGNC:18384] | 23378 | 0.000 | 0.0668 | No |
| 89 | SCGB1A1 | secretoglobin family 1A member 1 [Source:HGNC Symbol;Acc:HGNC:12523] | 24083 | 0.000 | 0.0478 | No |
| 90 | RARRES1 | retinoic acid receptor responder 1 [Source:HGNC Symbol;Acc:HGNC:9867] | 24218 | 0.000 | 0.0441 | No |
| 91 | CRYM | crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418] | 24290 | 0.000 | 0.0422 | No |
| 92 | MUC5B | mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7516] | 24298 | 0.000 | 0.0420 | No |
| 93 | SAA2 | serum amyloid A2 [Source:HGNC Symbol;Acc:HGNC:10514] | 24606 | 0.000 | 0.0337 | No |
| 94 | TFPI2 | tissue factor pathway inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:11761] | 24848 | 0.000 | 0.0272 | No |
| 95 | SLC4A4 | solute carrier family 4 member 4 [Source:HGNC Symbol;Acc:HGNC:11030] | 25183 | 0.000 | 0.0182 | No |
| 96 | RIMS1 | regulating synaptic membrane exocytosis 1 [Source:HGNC Symbol;Acc:HGNC:17282] | 25255 | 0.000 | 0.0162 | No |
| 97 | ALDH1A3 | aldehyde dehydrogenase 1 family member A3 [Source:HGNC Symbol;Acc:HGNC:409] | 25530 | 0.000 | 0.0088 | No |
| 98 | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 25578 | 0.000 | 0.0076 | No |
| 99 | AZGP1 | alpha-2-glycoprotein 1, zinc-binding [Source:HGNC Symbol;Acc:HGNC:910] | 26550 | 0.000 | -0.0187 | No |
| 100 | FCGBP | Fc fragment of IgG binding protein [Source:HGNC Symbol;Acc:HGNC:13572] | 26618 | 0.000 | -0.0205 | No |
| 101 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 27603 | -0.044 | -0.0467 | No |
| 102 | BID | BH3 interacting domain death agonist [Source:HGNC Symbol;Acc:HGNC:1050] | 27652 | -0.054 | -0.0474 | No |
| 103 | ATP12A | ATPase H+/K+ transporting non-gastric alpha2 subunit [Source:HGNC Symbol;Acc:HGNC:13816] | 27827 | -0.080 | -0.0512 | No |
| 104 | RDH10 | retinol dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:19975] | 28154 | -0.128 | -0.0586 | No |
| 105 | SLC26A2 | solute carrier family 26 member 2 [Source:HGNC Symbol;Acc:HGNC:10994] | 28638 | -0.194 | -0.0696 | No |
| 106 | RASD1 | ras related dexamethasone induced 1 [Source:HGNC Symbol;Acc:HGNC:15828] | 28788 | -0.215 | -0.0713 | No |
| 107 | CSTB | cystatin B [Source:HGNC Symbol;Acc:HGNC:2482] | 28832 | -0.222 | -0.0701 | No |
| 108 | IRAK3 | interleukin 1 receptor associated kinase 3 [Source:HGNC Symbol;Acc:HGNC:17020] | 29344 | -0.303 | -0.0806 | No |
| 109 | CP | ceruloplasmin [Source:HGNC Symbol;Acc:HGNC:2295] | 29610 | -0.342 | -0.0841 | No |
| 110 | HIPK2 | homeodomain interacting protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:14402] | 29639 | -0.347 | -0.0811 | No |
| 111 | DUSP23 | dual specificity phosphatase 23 [Source:HGNC Symbol;Acc:HGNC:21480] | 29786 | -0.366 | -0.0811 | No |
| 112 | RPS26 | ribosomal protein S26 [Source:HGNC Symbol;Acc:HGNC:10414] | 30840 | -0.533 | -0.1038 | No |
| 113 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 30863 | -0.537 | -0.0986 | No |
| 114 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 31733 | -0.697 | -0.1145 | No |
| 115 | CTSB | cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527] | 31918 | -0.735 | -0.1116 | No |
| 116 | ANPEP | alanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500] | 32022 | -0.759 | -0.1062 | No |
| 117 | CBR3 | carbonyl reductase 3 [Source:HGNC Symbol;Acc:HGNC:1549] | 32329 | -0.845 | -0.1053 | No |
| 118 | STT3B | STT3 oligosaccharyltransferase complex catalytic subunit B [Source:HGNC Symbol;Acc:HGNC:30611] | 33908 | -1.339 | -0.1335 | No |
| 119 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 34769 | -1.684 | -0.1386 | No |
| 120 | ERO1A | endoplasmic reticulum oxidoreductase 1 alpha [Source:HGNC Symbol;Acc:HGNC:13280] | 35593 | -2.193 | -0.1371 | No |
| 121 | INSR | insulin receptor [Source:HGNC Symbol;Acc:HGNC:6091] | 36144 | -2.700 | -0.1228 | No |
| 122 | SORD | sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184] | 36253 | -2.795 | -0.0955 | No |
| 123 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36658 | -3.366 | -0.0700 | No |
| 124 | PTP4A3 | protein tyrosine phosphatase 4A3 [Source:HGNC Symbol;Acc:HGNC:9636] | 36735 | -3.479 | -0.0344 | No |
| 125 | SLC9A3R2 | SLC9A3 regulator 2 [Source:HGNC Symbol;Acc:HGNC:11076] | 36961 | -4.067 | 0.0035 | No |
