Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | TRAVAGLINI_LUNG_PROLIFERATING_NK_T_CELL |
| Enrichment Score (ES) | -0.822113 |
| Normalized Enrichment Score (NES) | -1.7158686 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 30 | 4.738 | 0.0194 | No |
| 2 | RANBP1 | RAN binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9847] | 2017 | 0.936 | -0.0303 | No |
| 3 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2428 | 0.770 | -0.0381 | No |
| 4 | PSMD8 | proteasome 26S subunit, non-ATPase 8 [Source:HGNC Symbol;Acc:HGNC:9566] | 2720 | 0.670 | -0.0431 | No |
| 5 | PPIA | peptidylprolyl isomerase A [Source:HGNC Symbol;Acc:HGNC:9253] | 3195 | 0.555 | -0.0536 | No |
| 6 | NUCB2 | nucleobindin 2 [Source:HGNC Symbol;Acc:HGNC:8044] | 3308 | 0.525 | -0.0544 | No |
| 7 | IGFBP7 | insulin like growth factor binding protein 7 [Source:HGNC Symbol;Acc:HGNC:5476] | 3906 | 0.398 | -0.0688 | No |
| 8 | SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 [Source:HGNC Symbol;Acc:HGNC:11153] | 4163 | 0.348 | -0.0743 | No |
| 9 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 4200 | 0.339 | -0.0738 | No |
| 10 | RCC1 | regulator of chromosome condensation 1 [Source:HGNC Symbol;Acc:HGNC:1913] | 4226 | 0.334 | -0.0731 | No |
| 11 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 4498 | 0.278 | -0.0792 | No |
| 12 | PSMC3 | proteasome 26S subunit, ATPase 3 [Source:HGNC Symbol;Acc:HGNC:9549] | 4564 | 0.264 | -0.0798 | No |
| 13 | CD160 | CD160 molecule [Source:HGNC Symbol;Acc:HGNC:17013] | 7384 | 0.000 | -0.1561 | No |
| 14 | C21orf58 | chromosome 21 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:1300] | 10449 | 0.000 | -0.2390 | No |
| 15 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 11887 | 0.000 | -0.2779 | No |
| 16 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12314 | 0.000 | -0.2894 | No |
| 17 | C12orf75 | chromosome 12 open reading frame 75 [Source:HGNC Symbol;Acc:HGNC:35164] | 12584 | 0.000 | -0.2967 | No |
| 18 | SH2D1B | SH2 domain containing 1B [Source:HGNC Symbol;Acc:HGNC:30416] | 15837 | 0.000 | -0.3846 | No |
| 19 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 17920 | 0.000 | -0.4410 | No |
| 20 | ICAM2 | intercellular adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:5345] | 18186 | 0.000 | -0.4481 | No |
| 21 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22346 | 0.000 | -0.5607 | No |
| 22 | KLRF1 | killer cell lectin like receptor F1 [Source:HGNC Symbol;Acc:HGNC:13342] | 23793 | 0.000 | -0.5998 | No |
| 23 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 23982 | 0.000 | -0.6049 | No |
| 24 | HMGN3 | high mobility group nucleosomal binding domain 3 [Source:HGNC Symbol;Acc:HGNC:12312] | 24395 | 0.000 | -0.6160 | No |
| 25 | PRSS23 | serine protease 23 [Source:HGNC Symbol;Acc:HGNC:14370] | 25130 | 0.000 | -0.6359 | No |
| 26 | FGFBP2 | fibroblast growth factor binding protein 2 [Source:HGNC Symbol;Acc:HGNC:29451] | 25622 | 0.000 | -0.6492 | No |
| 27 | CCDC167 | coiled-coil domain containing 167 [Source:HGNC Symbol;Acc:HGNC:21239] | 25761 | 0.000 | -0.6529 | No |
| 28 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26019 | 0.000 | -0.6598 | No |
| 29 | GGH | gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] | 27673 | -0.057 | -0.7043 | No |
| 30 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 29048 | -0.257 | -0.7404 | No |
| 31 | DCTN3 | dynactin subunit 3 [Source:HGNC Symbol;Acc:HGNC:2713] | 29252 | -0.290 | -0.7446 | No |
| 32 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 31016 | -0.561 | -0.7899 | No |
| 33 | SNRNP25 | small nuclear ribonucleoprotein U11/U12 subunit 25 [Source:HGNC Symbol;Acc:HGNC:14161] | 31031 | -0.564 | -0.7879 | No |
| 34 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31383 | -0.630 | -0.7947 | No |
| 35 | POLQ | DNA polymerase theta [Source:HGNC Symbol;Acc:HGNC:9186] | 31932 | -0.738 | -0.8064 | No |
| 36 | LSM5 | LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17162] | 32042 | -0.765 | -0.8061 | No |
| 37 | MND1 | meiotic nuclear divisions 1 [Source:HGNC Symbol;Acc:HGNC:24839] | 32109 | -0.782 | -0.8045 | No |
| 38 | AKR1C3 | aldo-keto reductase family 1 member C3 [Source:HGNC Symbol;Acc:HGNC:386] | 32315 | -0.842 | -0.8065 | No |
| 39 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32418 | -0.869 | -0.8055 | No |
| 40 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32753 | -0.958 | -0.8105 | No |
| 41 | SKA3 | spindle and kinetochore associated complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:20262] | 32830 | -0.984 | -0.8083 | No |
| 42 | HPRT1 | hypoxanthine phosphoribosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:5157] | 33340 | -1.140 | -0.8172 | Yes |
| 43 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33397 | -1.158 | -0.8138 | Yes |
| 44 | APMAP | adipocyte plasma membrane associated protein [Source:HGNC Symbol;Acc:HGNC:13238] | 33458 | -1.174 | -0.8104 | Yes |
| 45 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 33741 | -1.280 | -0.8126 | Yes |
| 46 | TROAP | trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327] | 33756 | -1.284 | -0.8075 | Yes |
| 47 | SKA2 | spindle and kinetochore associated complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:28006] | 33850 | -1.319 | -0.8044 | Yes |
| 48 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 33916 | -1.342 | -0.8004 | Yes |
| 49 | DIAPH3 | diaphanous related formin 3 [Source:HGNC Symbol;Acc:HGNC:15480] | 33930 | -1.347 | -0.7950 | Yes |
| 50 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 34095 | -1.401 | -0.7935 | Yes |
| 51 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 34140 | -1.424 | -0.7886 | Yes |
| 52 | CDC25C | cell division cycle 25C [Source:HGNC Symbol;Acc:HGNC:1727] | 34146 | -1.427 | -0.7826 | Yes |
| 53 | CENPU | centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348] | 34297 | -1.486 | -0.7803 | Yes |
| 54 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34312 | -1.491 | -0.7744 | Yes |
| 55 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34381 | -1.518 | -0.7697 | Yes |
| 56 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 34524 | -1.572 | -0.7669 | Yes |
| 57 | ZNF367 | zinc finger protein 367 [Source:HGNC Symbol;Acc:HGNC:18320] | 34624 | -1.612 | -0.7627 | Yes |
| 58 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34638 | -1.617 | -0.7561 | Yes |
| 59 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34684 | -1.643 | -0.7503 | Yes |
| 60 | PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 [Source:HGNC Symbol;Acc:HGNC:29650] | 34732 | -1.666 | -0.7445 | Yes |
| 61 | FANCD2 | FA complementation group D2 [Source:HGNC Symbol;Acc:HGNC:3585] | 34824 | -1.707 | -0.7396 | Yes |
| 62 | H2AZ1 | H2A.Z variant histone 1 [Source:HGNC Symbol;Acc:HGNC:4741] | 34958 | -1.777 | -0.7357 | Yes |
| 63 | PXMP2 | peroxisomal membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:9716] | 34959 | -1.778 | -0.7281 | Yes |
| 64 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35062 | -1.840 | -0.7230 | Yes |
| 65 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35131 | -1.888 | -0.7168 | Yes |
| 66 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35138 | -1.892 | -0.7088 | Yes |
| 67 | NUDT1 | nudix hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:8048] | 35141 | -1.895 | -0.7008 | Yes |
| 68 | CDT1 | chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576] | 35143 | -1.895 | -0.6928 | Yes |
| 69 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35192 | -1.927 | -0.6858 | Yes |
| 70 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35217 | -1.946 | -0.6782 | Yes |
| 71 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 35318 | -2.003 | -0.6723 | Yes |
| 72 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 35348 | -2.023 | -0.6645 | Yes |
| 73 | CENPN | centromere protein N [Source:HGNC Symbol;Acc:HGNC:30873] | 35359 | -2.031 | -0.6561 | Yes |
| 74 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 35373 | -2.046 | -0.6477 | Yes |
| 75 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35407 | -2.067 | -0.6398 | Yes |
| 76 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35510 | -2.132 | -0.6334 | Yes |
| 77 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35632 | -2.222 | -0.6272 | Yes |
| 78 | TUBA1B | tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809] | 35701 | -2.280 | -0.6193 | Yes |
| 79 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35759 | -2.331 | -0.6109 | Yes |
| 80 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 35779 | -2.351 | -0.6014 | Yes |
| 81 | HELLS | helicase, lymphoid specific [Source:HGNC Symbol;Acc:HGNC:4861] | 35800 | -2.370 | -0.5918 | Yes |
| 82 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35807 | -2.374 | -0.5819 | Yes |
| 83 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35813 | -2.385 | -0.5718 | Yes |
| 84 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35830 | -2.402 | -0.5620 | Yes |
| 85 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 35880 | -2.445 | -0.5529 | Yes |
| 86 | IDH2 | isocitrate dehydrogenase (NADP(+)) 2 [Source:HGNC Symbol;Acc:HGNC:5383] | 35904 | -2.462 | -0.5430 | Yes |
| 87 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35941 | -2.490 | -0.5334 | Yes |
| 88 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35993 | -2.546 | -0.5239 | Yes |
| 89 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36065 | -2.624 | -0.5146 | Yes |
| 90 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 36069 | -2.626 | -0.5035 | Yes |
| 91 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36083 | -2.637 | -0.4926 | Yes |
| 92 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36125 | -2.680 | -0.4822 | Yes |
| 93 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36129 | -2.683 | -0.4709 | Yes |
| 94 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36191 | -2.745 | -0.4608 | Yes |
| 95 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36199 | -2.753 | -0.4492 | Yes |
| 96 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36208 | -2.759 | -0.4377 | Yes |
| 97 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36251 | -2.795 | -0.4269 | Yes |
| 98 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36260 | -2.803 | -0.4151 | Yes |
| 99 | ATAD2 | ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123] | 36303 | -2.848 | -0.4041 | Yes |
| 100 | EBP | EBP cholestenol delta-isomerase [Source:HGNC Symbol;Acc:HGNC:3133] | 36330 | -2.895 | -0.3925 | Yes |
| 101 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36357 | -2.930 | -0.3807 | Yes |
| 102 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36421 | -3.011 | -0.3695 | Yes |
| 103 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36426 | -3.017 | -0.3568 | Yes |
| 104 | ATAD5 | ATPase family AAA domain containing 5 [Source:HGNC Symbol;Acc:HGNC:25752] | 36431 | -3.025 | -0.3439 | Yes |
| 105 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36439 | -3.036 | -0.3312 | Yes |
| 106 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36461 | -3.062 | -0.3187 | Yes |
| 107 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36476 | -3.083 | -0.3059 | Yes |
| 108 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36508 | -3.121 | -0.2934 | Yes |
| 109 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36546 | -3.187 | -0.2808 | Yes |
| 110 | TMEM106C | transmembrane protein 106C [Source:HGNC Symbol;Acc:HGNC:28775] | 36562 | -3.211 | -0.2675 | Yes |
| 111 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36575 | -3.228 | -0.2541 | Yes |
| 112 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36635 | -3.330 | -0.2415 | Yes |
| 113 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36660 | -3.369 | -0.2277 | Yes |
| 114 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36664 | -3.374 | -0.2134 | Yes |
| 115 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36691 | -3.417 | -0.1995 | Yes |
| 116 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36698 | -3.424 | -0.1851 | Yes |
| 117 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36700 | -3.426 | -0.1705 | Yes |
| 118 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36705 | -3.438 | -0.1559 | Yes |
| 119 | BRCA2 | BRCA2 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1101] | 36707 | -3.439 | -0.1413 | Yes |
| 120 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36710 | -3.442 | -0.1266 | Yes |
| 121 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36808 | -3.649 | -0.1137 | Yes |
| 122 | CLSPN | claspin [Source:HGNC Symbol;Acc:HGNC:19715] | 36829 | -3.704 | -0.0984 | Yes |
| 123 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36873 | -3.821 | -0.0833 | Yes |
| 124 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36920 | -3.941 | -0.0677 | Yes |
| 125 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36939 | -3.976 | -0.0512 | Yes |
| 126 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36969 | -4.093 | -0.0345 | Yes |
| 127 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36994 | -4.180 | -0.0173 | Yes |
| 128 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37070 | -4.666 | 0.0005 | Yes |
