Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | HALLMARK_CHOLESTEROL_HOMEOSTASIS |
| Enrichment Score (ES) | -0.5861146 |
| Normalized Enrichment Score (NES) | -1.168555 |
| Nominal p-value | 0.18118466 |
| FDR q-value | 0.36487335 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ACTG1 | actin gamma 1 [Source:HGNC Symbol;Acc:HGNC:144] | 354 | 2.739 | 0.0188 | No |
| 2 | ERRFI1 | ERBB receptor feedback inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:18185] | 376 | 2.691 | 0.0461 | No |
| 3 | S100A11 | S100 calcium binding protein A11 [Source:HGNC Symbol;Acc:HGNC:10488] | 478 | 2.413 | 0.0683 | No |
| 4 | ATF3 | activating transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:785] | 642 | 2.069 | 0.0853 | No |
| 5 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 680 | 1.985 | 0.1049 | No |
| 6 | ALCAM | activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400] | 926 | 1.658 | 0.1154 | No |
| 7 | CHKA | choline kinase alpha [Source:HGNC Symbol;Acc:HGNC:1937] | 1065 | 1.504 | 0.1272 | No |
| 8 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006] | 1144 | 1.431 | 0.1400 | No |
| 9 | ANTXR2 | ANTXR cell adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:21732] | 1369 | 1.266 | 0.1470 | No |
| 10 | GNAI1 | G protein subunit alpha i1 [Source:HGNC Symbol;Acc:HGNC:4384] | 1531 | 1.178 | 0.1549 | No |
| 11 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 1685 | 1.099 | 0.1621 | No |
| 12 | LDLR | low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:6547] | 1915 | 0.988 | 0.1661 | No |
| 13 | ANXA5 | annexin A5 [Source:HGNC Symbol;Acc:HGNC:543] | 2228 | 0.846 | 0.1665 | No |
| 14 | GLDC | glycine decarboxylase [Source:HGNC Symbol;Acc:HGNC:4313] | 3325 | 0.522 | 0.1422 | No |
| 15 | LPL | lipoprotein lipase [Source:HGNC Symbol;Acc:HGNC:6677] | 3442 | 0.497 | 0.1443 | No |
| 16 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 3891 | 0.402 | 0.1363 | No |
| 17 | HSD17B7 | hydroxysteroid 17-beta dehydrogenase 7 [Source:HGNC Symbol;Acc:HGNC:5215] | 4068 | 0.364 | 0.1353 | No |
| 18 | IDI1 | isopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5387] | 4110 | 0.358 | 0.1379 | No |
| 19 | FABP5 | fatty acid binding protein 5 [Source:HGNC Symbol;Acc:HGNC:3560] | 4180 | 0.344 | 0.1396 | No |
| 20 | GPX8 | glutathione peroxidase 8 (putative) [Source:HGNC Symbol;Acc:HGNC:33100] | 9201 | 0.000 | 0.0040 | No |
| 21 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9381 | 0.000 | -0.0008 | No |
| 22 | ADH4 | alcohol dehydrogenase 4 (class II), pi polypeptide [Source:HGNC Symbol;Acc:HGNC:252] | 10822 | 0.000 | -0.0397 | No |
| 23 | ANXA13 | annexin A13 [Source:HGNC Symbol;Acc:HGNC:536] | 14143 | 0.000 | -0.1294 | No |
| 24 | AVPR1A | arginine vasopressin receptor 1A [Source:HGNC Symbol;Acc:HGNC:895] | 16557 | 0.000 | -0.1946 | No |
| 25 | SEMA3B | semaphorin 3B [Source:HGNC Symbol;Acc:HGNC:10724] | 17801 | 0.000 | -0.2282 | No |
| 26 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18810 | 0.000 | -0.2554 | No |
| 27 | PLAUR | plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053] | 25527 | 0.000 | -0.4368 | No |
| 28 | MAL2 | mal, T cell differentiation protein 2 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:13634] | 27190 | 0.000 | -0.4817 | No |
| 29 | TNFRSF12A | TNF receptor superfamily member 12A [Source:HGNC Symbol;Acc:HGNC:18152] | 27785 | -0.075 | -0.4970 | No |
| 30 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 27941 | -0.095 | -0.5002 | No |
| 31 | CTNNB1 | catenin beta 1 [Source:HGNC Symbol;Acc:HGNC:2514] | 28155 | -0.129 | -0.5046 | No |
| 32 | STARD4 | StAR related lipid transfer domain containing 4 [Source:HGNC Symbol;Acc:HGNC:18058] | 29498 | -0.326 | -0.5375 | No |
| 33 | CYP51A1 | cytochrome P450 family 51 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2649] | 29564 | -0.336 | -0.5358 | No |
| 34 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 29898 | -0.382 | -0.5408 | No |
| 35 | TRIB3 | tribbles pseudokinase 3 [Source:HGNC Symbol;Acc:HGNC:16228] | 29921 | -0.385 | -0.5374 | No |
| 36 | NIBAN1 | niban apoptosis regulator 1 [Source:HGNC Symbol;Acc:HGNC:16784] | 29927 | -0.386 | -0.5336 | No |
| 37 | HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 [Source:HGNC Symbol;Acc:HGNC:5007] | 29931 | -0.388 | -0.5297 | No |
| 38 | STX5 | syntaxin 5 [Source:HGNC Symbol;Acc:HGNC:11440] | 30636 | -0.501 | -0.5435 | No |
| 39 | FASN | fatty acid synthase [Source:HGNC Symbol;Acc:HGNC:3594] | 31476 | -0.647 | -0.5595 | No |
| 40 | JAG1 | jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188] | 32464 | -0.879 | -0.5770 | Yes |
| 41 | TMEM97 | transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106] | 32741 | -0.956 | -0.5746 | Yes |
| 42 | LSS | lanosterol synthase [Source:HGNC Symbol;Acc:HGNC:6708] | 32809 | -0.976 | -0.5663 | Yes |
| 43 | SREBF2 | sterol regulatory element binding transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11290] | 32824 | -0.981 | -0.5565 | Yes |
| 44 | FBXO6 | F-box protein 6 [Source:HGNC Symbol;Acc:HGNC:13585] | 32999 | -1.036 | -0.5505 | Yes |
| 45 | CPEB2 | cytoplasmic polyadenylation element binding protein 2 [Source:HGNC Symbol;Acc:HGNC:21745] | 33015 | -1.041 | -0.5401 | Yes |
| 46 | TP53INP1 | tumor protein p53 inducible nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:18022] | 33197 | -1.094 | -0.5337 | Yes |
| 47 | PPARG | peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236] | 33389 | -1.156 | -0.5269 | Yes |
| 48 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 33460 | -1.175 | -0.5166 | Yes |
| 49 | GUSB | glucuronidase beta [Source:HGNC Symbol;Acc:HGNC:4696] | 33461 | -1.176 | -0.5044 | Yes |
| 50 | TM7SF2 | transmembrane 7 superfamily member 2 [Source:HGNC Symbol;Acc:HGNC:11863] | 33645 | -1.248 | -0.4965 | Yes |
| 51 | ATXN2 | ataxin 2 [Source:HGNC Symbol;Acc:HGNC:10555] | 33789 | -1.297 | -0.4869 | Yes |
| 52 | PDK3 | pyruvate dehydrogenase kinase 3 [Source:HGNC Symbol;Acc:HGNC:8811] | 33830 | -1.313 | -0.4744 | Yes |
| 53 | FDFT1 | farnesyl-diphosphate farnesyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:3629] | 33860 | -1.322 | -0.4615 | Yes |
| 54 | SC5D | sterol-C5-desaturase [Source:HGNC Symbol;Acc:HGNC:10547] | 33981 | -1.365 | -0.4506 | Yes |
| 55 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 34044 | -1.384 | -0.4379 | Yes |
| 56 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 34061 | -1.392 | -0.4240 | Yes |
| 57 | MVK | mevalonate kinase [Source:HGNC Symbol;Acc:HGNC:7530] | 34238 | -1.462 | -0.4136 | Yes |
| 58 | FDPS | farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631] | 34500 | -1.563 | -0.4045 | Yes |
| 59 | MVD | mevalonate diphosphate decarboxylase [Source:HGNC Symbol;Acc:HGNC:7529] | 34759 | -1.679 | -0.3941 | Yes |
| 60 | ABCA2 | ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32] | 35346 | -2.023 | -0.3890 | Yes |
| 61 | LGALS3 | galectin 3 [Source:HGNC Symbol;Acc:HGNC:6563] | 35353 | -2.028 | -0.3681 | Yes |
| 62 | CBS | cystathionine beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550] | 35580 | -2.179 | -0.3517 | Yes |
| 63 | ALDOC | aldolase, fructose-bisphosphate C [Source:HGNC Symbol;Acc:HGNC:418] | 35671 | -2.246 | -0.3309 | Yes |
| 64 | PNRC1 | proline rich nuclear receptor coactivator 1 [Source:HGNC Symbol;Acc:HGNC:17278] | 35915 | -2.472 | -0.3118 | Yes |
| 65 | PCYT2 | phosphate cytidylyltransferase 2, ethanolamine [Source:HGNC Symbol;Acc:HGNC:8756] | 36202 | -2.754 | -0.2911 | Yes |
| 66 | EBP | EBP cholestenol delta-isomerase [Source:HGNC Symbol;Acc:HGNC:3133] | 36330 | -2.895 | -0.2645 | Yes |
| 67 | ACAT2 | acetyl-CoA acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:94] | 36355 | -2.927 | -0.2349 | Yes |
| 68 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 36496 | -3.107 | -0.2065 | Yes |
| 69 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36606 | -3.271 | -0.1756 | Yes |
| 70 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 36607 | -3.272 | -0.1417 | Yes |
| 71 | FADS2 | fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575] | 36612 | -3.282 | -0.1079 | Yes |
| 72 | DHCR7 | 7-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2860] | 36681 | -3.406 | -0.0744 | Yes |
| 73 | ACSS2 | acyl-CoA synthetase short chain family member 2 [Source:HGNC Symbol;Acc:HGNC:15814] | 36857 | -3.783 | -0.0400 | Yes |
| 74 | SCD | stearoyl-CoA desaturase [Source:HGNC Symbol;Acc:HGNC:10571] | 37047 | -4.472 | 0.0012 | Yes |
