Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | HALLMARK_INTERFERON_ALPHA_RESPONSE |
| Enrichment Score (ES) | 0.8608462 |
| Normalized Enrichment Score (NES) | 2.1649032 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 15 | 4.872 | 0.0222 | Yes |
| 2 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 18 | 4.849 | 0.0446 | Yes |
| 3 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 20 | 4.828 | 0.0670 | Yes |
| 4 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 21 | 4.823 | 0.0894 | Yes |
| 5 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 35 | 4.665 | 0.1106 | Yes |
| 6 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 37 | 4.663 | 0.1322 | Yes |
| 7 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 46 | 4.543 | 0.1531 | Yes |
| 8 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 47 | 4.510 | 0.1740 | Yes |
| 9 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 51 | 4.480 | 0.1947 | Yes |
| 10 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 54 | 4.451 | 0.2153 | Yes |
| 11 | IFIH1 | interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873] | 57 | 4.431 | 0.2358 | Yes |
| 12 | PROCR | protein C receptor [Source:HGNC Symbol;Acc:HGNC:9452] | 75 | 4.251 | 0.2550 | Yes |
| 13 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 77 | 4.236 | 0.2747 | Yes |
| 14 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 91 | 4.106 | 0.2933 | Yes |
| 15 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 94 | 4.083 | 0.3122 | Yes |
| 16 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 96 | 4.071 | 0.3311 | Yes |
| 17 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 103 | 4.026 | 0.3496 | Yes |
| 18 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 110 | 3.966 | 0.3678 | Yes |
| 19 | TRAFD1 | TRAF-type zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24808] | 112 | 3.965 | 0.3862 | Yes |
| 20 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 118 | 3.942 | 0.4043 | Yes |
| 21 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 124 | 3.916 | 0.4224 | Yes |
| 22 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 128 | 3.902 | 0.4404 | Yes |
| 23 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 133 | 3.882 | 0.4583 | Yes |
| 24 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 154 | 3.699 | 0.4749 | Yes |
| 25 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 172 | 3.617 | 0.4912 | Yes |
| 26 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 174 | 3.614 | 0.5079 | Yes |
| 27 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 177 | 3.589 | 0.5245 | Yes |
| 28 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 186 | 3.543 | 0.5407 | Yes |
| 29 | TRIM21 | tripartite motif containing 21 [Source:HGNC Symbol;Acc:HGNC:11312] | 195 | 3.470 | 0.5566 | Yes |
| 30 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 208 | 3.392 | 0.5720 | Yes |
| 31 | MOV10 | Mov10 RISC complex RNA helicase [Source:HGNC Symbol;Acc:HGNC:7200] | 209 | 3.391 | 0.5877 | Yes |
| 32 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 220 | 3.316 | 0.6028 | Yes |
| 33 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 237 | 3.234 | 0.6174 | Yes |
| 34 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 238 | 3.232 | 0.6324 | Yes |
| 35 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 293 | 2.972 | 0.6447 | Yes |
| 36 | ADAR | adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225] | 335 | 2.806 | 0.6566 | Yes |
| 37 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 397 | 2.625 | 0.6672 | Yes |
| 38 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 404 | 2.597 | 0.6790 | Yes |
| 39 | CD47 | CD47 molecule [Source:HGNC Symbol;Acc:HGNC:1682] | 443 | 2.491 | 0.6896 | Yes |
| 40 | TDRD7 | tudor domain containing 7 [Source:HGNC Symbol;Acc:HGNC:30831] | 449 | 2.472 | 0.7009 | Yes |
| 41 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 468 | 2.436 | 0.7117 | Yes |
| 42 | IRF1 | interferon regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:6116] | 496 | 2.371 | 0.7220 | Yes |
| 43 | CASP8 | caspase 8 [Source:HGNC Symbol;Acc:HGNC:1509] | 501 | 2.363 | 0.7328 | Yes |
| 44 | UBA7 | ubiquitin like modifier activating enzyme 7 [Source:HGNC Symbol;Acc:HGNC:12471] | 503 | 2.360 | 0.7437 | Yes |
| 45 | IRF9 | interferon regulatory factor 9 [Source:HGNC Symbol;Acc:HGNC:6131] | 510 | 2.341 | 0.7544 | Yes |
| 46 | TENT5A | terminal nucleotidyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:18345] | 530 | 2.279 | 0.7645 | Yes |
| 47 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 580 | 2.164 | 0.7732 | Yes |
| 48 | IFITM2 | interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413] | 629 | 2.094 | 0.7816 | Yes |
| 49 | OGFR | opioid growth factor receptor [Source:HGNC Symbol;Acc:HGNC:15768] | 643 | 2.067 | 0.7908 | Yes |
| 50 | PSMB8 | proteasome 20S subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:9545] | 697 | 1.961 | 0.7985 | Yes |
| 51 | CMTR1 | cap methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:21077] | 704 | 1.954 | 0.8074 | Yes |
| 52 | PSMB9 | proteasome 20S subunit beta 9 [Source:HGNC Symbol;Acc:HGNC:9546] | 764 | 1.869 | 0.8145 | Yes |
| 53 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 774 | 1.859 | 0.8229 | Yes |
| 54 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 802 | 1.811 | 0.8305 | Yes |
| 55 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 941 | 1.639 | 0.8344 | Yes |
| 56 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 1072 | 1.497 | 0.8378 | Yes |
| 57 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 1117 | 1.452 | 0.8434 | Yes |
| 58 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 1150 | 1.427 | 0.8491 | Yes |
| 59 | TRIM14 | tripartite motif containing 14 [Source:HGNC Symbol;Acc:HGNC:16283] | 1225 | 1.371 | 0.8535 | Yes |
| 60 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 1412 | 1.240 | 0.8542 | Yes |
| 61 | PSMA3 | proteasome 20S subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:9532] | 1570 | 1.166 | 0.8554 | Yes |
| 62 | TRIM26 | tripartite motif containing 26 [Source:HGNC Symbol;Acc:HGNC:12962] | 1580 | 1.155 | 0.8605 | Yes |
| 63 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 1772 | 1.050 | 0.8602 | Yes |
| 64 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 1918 | 0.987 | 0.8608 | Yes |
| 65 | WARS1 | tryptophanyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12729] | 3344 | 0.518 | 0.8247 | No |
| 66 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 3430 | 0.500 | 0.8248 | No |
| 67 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 3728 | 0.434 | 0.8187 | No |
| 68 | SP110 | SP110 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:5401] | 3840 | 0.413 | 0.8176 | No |
| 69 | NUB1 | negative regulator of ubiquitin like proteins 1 [Source:HGNC Symbol;Acc:HGNC:17623] | 4278 | 0.324 | 0.8073 | No |
| 70 | B2M | beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914] | 4631 | 0.246 | 0.7990 | No |
| 71 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 4688 | 0.239 | 0.7986 | No |
| 72 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 6807 | 0.000 | 0.7413 | No |
| 73 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8385 | 0.000 | 0.6987 | No |
| 74 | BATF2 | basic leucine zipper ATF-like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:25163] | 8505 | 0.000 | 0.6955 | No |
| 75 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 8858 | 0.000 | 0.6860 | No |
| 76 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10224 | 0.000 | 0.6491 | No |
| 77 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11204 | 0.000 | 0.6226 | No |
| 78 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12304 | 0.000 | 0.5929 | No |
| 79 | IL4R | interleukin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6015] | 13696 | 0.000 | 0.5553 | No |
| 80 | TRIM5 | tripartite motif containing 5 [Source:HGNC Symbol;Acc:HGNC:16276] | 17739 | 0.000 | 0.4460 | No |
| 81 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 19249 | 0.000 | 0.4052 | No |
| 82 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 23524 | 0.000 | 0.2897 | No |
| 83 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24394 | 0.000 | 0.2662 | No |
| 84 | IRF2 | interferon regulatory factor 2 [Source:HGNC Symbol;Acc:HGNC:6117] | 27482 | -0.022 | 0.1829 | No |
| 85 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 27941 | -0.095 | 0.1709 | No |
| 86 | IL7 | interleukin 7 [Source:HGNC Symbol;Acc:HGNC:6023] | 29919 | -0.385 | 0.1193 | No |
| 87 | ELF1 | E74 like ETS transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3316] | 30789 | -0.524 | 0.0982 | No |
| 88 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 30895 | -0.541 | 0.0979 | No |
| 89 | NCOA7 | nuclear receptor coactivator 7 [Source:HGNC Symbol;Acc:HGNC:21081] | 31873 | -0.724 | 0.0748 | No |
| 90 | SLC25A28 | solute carrier family 25 member 28 [Source:HGNC Symbol;Acc:HGNC:23472] | 32621 | -0.923 | 0.0589 | No |
| 91 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 32733 | -0.955 | 0.0603 | No |
| 92 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 32794 | -0.972 | 0.0632 | No |
| 93 | MVB12A | multivesicular body subunit 12A [Source:HGNC Symbol;Acc:HGNC:25153] | 33243 | -1.111 | 0.0563 | No |
| 94 | CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase [Source:HGNC Symbol;Acc:HGNC:2158] | 33327 | -1.137 | 0.0593 | No |
| 95 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 35275 | -1.977 | 0.0158 | No |
| 96 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36442 | -3.043 | -0.0016 | No |
| 97 | GMPR | guanosine monophosphate reductase [Source:HGNC Symbol;Acc:HGNC:4376] | 36978 | -4.110 | 0.0030 | No |
