Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | HALLMARK_MYC_TARGETS_V2 |
| Enrichment Score (ES) | 0.42304403 |
| Normalized Enrichment Score (NES) | 0.99324054 |
| Nominal p-value | 0.45555556 |
| FDR q-value | 0.4541729 |
| FWER p-Value | 0.85 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 30 | 4.738 | 0.0671 | Yes |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 61 | 4.405 | 0.1294 | Yes |
| 3 | RRP12 | ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100] | 596 | 2.140 | 0.1457 | Yes |
| 4 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 612 | 2.130 | 0.1758 | Yes |
| 5 | RRP9 | ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829] | 699 | 1.960 | 0.2016 | Yes |
| 6 | GRWD1 | glutamate rich WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:21270] | 706 | 1.950 | 0.2294 | Yes |
| 7 | MYBBP1A | MYB binding protein 1a [Source:HGNC Symbol;Acc:HGNC:7546] | 762 | 1.871 | 0.2547 | Yes |
| 8 | NIP7 | nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328] | 944 | 1.638 | 0.2733 | Yes |
| 9 | UTP20 | UTP20 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897] | 1288 | 1.318 | 0.2829 | Yes |
| 10 | WDR43 | WD repeat domain 43 [Source:HGNC Symbol;Acc:HGNC:28945] | 1316 | 1.307 | 0.3009 | Yes |
| 11 | DDX18 | DEAD-box helicase 18 [Source:HGNC Symbol;Acc:HGNC:2741] | 1402 | 1.245 | 0.3164 | Yes |
| 12 | NOP2 | NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867] | 1452 | 1.218 | 0.3326 | Yes |
| 13 | NOP16 | NOP16 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:26934] | 1499 | 1.188 | 0.3484 | Yes |
| 14 | PPRC1 | PPARG related coactivator 1 [Source:HGNC Symbol;Acc:HGNC:30025] | 1534 | 1.178 | 0.3643 | Yes |
| 15 | TCOF1 | treacle ribosome biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:11654] | 1906 | 0.993 | 0.3685 | Yes |
| 16 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 2433 | 0.767 | 0.3653 | Yes |
| 17 | HK2 | hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923] | 2569 | 0.722 | 0.3720 | Yes |
| 18 | MRTO4 | MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477] | 2762 | 0.662 | 0.3763 | Yes |
| 19 | BYSL | bystin like [Source:HGNC Symbol;Acc:HGNC:1157] | 2909 | 0.622 | 0.3813 | Yes |
| 20 | SRM | spermidine synthase [Source:HGNC Symbol;Acc:HGNC:11296] | 3012 | 0.600 | 0.3872 | Yes |
| 21 | HSPD1 | heat shock protein family D (Hsp60) member 1 [Source:HGNC Symbol;Acc:HGNC:5261] | 3074 | 0.585 | 0.3939 | Yes |
| 22 | HSPE1 | heat shock protein family E (Hsp10) member 1 [Source:HGNC Symbol;Acc:HGNC:5269] | 3109 | 0.575 | 0.4012 | Yes |
| 23 | FARSA | phenylalanyl-tRNA synthetase subunit alpha [Source:HGNC Symbol;Acc:HGNC:3592] | 3196 | 0.554 | 0.4068 | Yes |
| 24 | MPHOSPH10 | M-phase phosphoprotein 10 [Source:HGNC Symbol;Acc:HGNC:7213] | 3234 | 0.543 | 0.4136 | Yes |
| 25 | PHB | prohibitin [Source:HGNC Symbol;Acc:HGNC:8912] | 3240 | 0.542 | 0.4213 | Yes |
| 26 | NOC4L | nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461] | 3471 | 0.489 | 0.4220 | Yes |
| 27 | PUS1 | pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:15508] | 3947 | 0.389 | 0.4148 | Yes |
| 28 | RCL1 | RNA terminal phosphate cyclase like 1 [Source:HGNC Symbol;Acc:HGNC:17687] | 4077 | 0.362 | 0.4165 | Yes |
| 29 | GNL3 | G protein nucleolar 3 [Source:HGNC Symbol;Acc:HGNC:29931] | 4132 | 0.353 | 0.4201 | Yes |
| 30 | NPM1 | nucleophosmin 1 [Source:HGNC Symbol;Acc:HGNC:7910] | 4396 | 0.296 | 0.4172 | Yes |
| 31 | LAS1L | LAS1 like ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:25726] | 4471 | 0.285 | 0.4193 | Yes |
| 32 | PES1 | pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8848] | 4484 | 0.282 | 0.4230 | Yes |
| 33 | AIMP2 | aminoacyl tRNA synthetase complex interacting multifunctional protein 2 [Source:HGNC Symbol;Acc:HGNC:20609] | 4967 | 0.184 | 0.4127 | No |
| 34 | NOLC1 | nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15608] | 4988 | 0.180 | 0.4147 | No |
| 35 | TBRG4 | transforming growth factor beta regulator 4 [Source:HGNC Symbol;Acc:HGNC:17443] | 5009 | 0.176 | 0.4167 | No |
| 36 | NOP56 | NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911] | 5045 | 0.169 | 0.4182 | No |
| 37 | WDR74 | WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529] | 5344 | 0.121 | 0.4119 | No |
| 38 | NDUFAF4 | NADH:ubiquinone oxidoreductase complex assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:21034] | 11919 | 0.000 | 0.2344 | No |
| 39 | IMP4 | IMP U3 small nucleolar ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:30856] | 27512 | -0.027 | -0.1863 | No |
| 40 | TFB2M | transcription factor B2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:18559] | 28216 | -0.137 | -0.2033 | No |
| 41 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 30896 | -0.541 | -0.2679 | No |
| 42 | PPAN | peter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227] | 31593 | -0.670 | -0.2771 | No |
| 43 | RABEPK | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] | 31781 | -0.704 | -0.2720 | No |
| 44 | PRMT3 | protein arginine methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30163] | 31844 | -0.714 | -0.2635 | No |
| 45 | SLC19A1 | solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937] | 32124 | -0.785 | -0.2598 | No |
| 46 | TMEM97 | transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106] | 32741 | -0.956 | -0.2627 | No |
| 47 | SUPV3L1 | Suv3 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:11471] | 33944 | -1.351 | -0.2758 | No |
| 48 | UNG | uracil DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:12572] | 34368 | -1.513 | -0.2655 | No |
| 49 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34684 | -1.643 | -0.2505 | No |
| 50 | CDK4 | cyclin dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773] | 34916 | -1.761 | -0.2315 | No |
| 51 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35101 | -1.865 | -0.2097 | No |
| 52 | SLC29A2 | solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004] | 35567 | -2.171 | -0.1912 | No |
| 53 | MAP3K6 | mitogen-activated protein kinase kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6858] | 35598 | -2.198 | -0.1605 | No |
| 54 | EXOSC5 | exosome component 5 [Source:HGNC Symbol;Acc:HGNC:24662] | 35600 | -2.199 | -0.1290 | No |
| 55 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35807 | -2.374 | -0.1005 | No |
| 56 | SORD | sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184] | 36253 | -2.795 | -0.0725 | No |
| 57 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36502 | -3.111 | -0.0346 | No |
| 58 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 36752 | -3.519 | 0.0091 | No |
