Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | HALLMARK_SPERMATOGENESIS |
| Enrichment Score (ES) | -0.64566875 |
| Normalized Enrichment Score (NES) | -1.3563817 |
| Nominal p-value | 0.007534984 |
| FDR q-value | 0.09313561 |
| FWER p-Value | 0.445 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DPEP3 | dipeptidase 3 [Source:HGNC Symbol;Acc:HGNC:23029] | 464 | 2.445 | 0.0120 | No |
| 2 | ELOVL3 | ELOVL fatty acid elongase 3 [Source:HGNC Symbol;Acc:HGNC:18047] | 529 | 2.280 | 0.0332 | No |
| 3 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 967 | 1.616 | 0.0376 | No |
| 4 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 1280 | 1.324 | 0.0425 | No |
| 5 | TLE4 | TLE family member 4, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11840] | 1310 | 1.309 | 0.0549 | No |
| 6 | STAM2 | signal transducing adaptor molecule 2 [Source:HGNC Symbol;Acc:HGNC:11358] | 1724 | 1.075 | 0.0545 | No |
| 7 | ARL4A | ADP ribosylation factor like GTPase 4A [Source:HGNC Symbol;Acc:HGNC:695] | 2129 | 0.884 | 0.0524 | No |
| 8 | PGS1 | phosphatidylglycerophosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:30029] | 2406 | 0.776 | 0.0528 | No |
| 9 | TSN | translin [Source:HGNC Symbol;Acc:HGNC:12379] | 3010 | 0.600 | 0.0425 | No |
| 10 | PAPOLB | poly(A) polymerase beta [Source:HGNC Symbol;Acc:HGNC:15970] | 3418 | 0.501 | 0.0365 | No |
| 11 | HSPA1L | heat shock protein family A (Hsp70) member 1 like [Source:HGNC Symbol;Acc:HGNC:5234] | 3594 | 0.460 | 0.0364 | No |
| 12 | RAD17 | RAD17 checkpoint clamp loader component [Source:HGNC Symbol;Acc:HGNC:9807] | 3875 | 0.406 | 0.0329 | No |
| 13 | TEKT2 | tektin 2 [Source:HGNC Symbol;Acc:HGNC:11725] | 3900 | 0.401 | 0.0363 | No |
| 14 | AGFG1 | ArfGAP with FG repeats 1 [Source:HGNC Symbol;Acc:HGNC:5175] | 4019 | 0.369 | 0.0368 | No |
| 15 | PIAS2 | protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311] | 4337 | 0.309 | 0.0313 | No |
| 16 | CSNK2A2 | casein kinase 2 alpha 2 [Source:HGNC Symbol;Acc:HGNC:2459] | 4500 | 0.278 | 0.0298 | No |
| 17 | OAZ3 | ornithine decarboxylase antizyme 3 [Source:HGNC Symbol;Acc:HGNC:8097] | 4717 | 0.233 | 0.0263 | No |
| 18 | RPL39L | ribosomal protein L39 like [Source:HGNC Symbol;Acc:HGNC:17094] | 5700 | 0.054 | 0.0002 | No |
| 19 | SCG5 | secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816] | 6191 | 0.000 | -0.0130 | No |
| 20 | SCG3 | secretogranin III [Source:HGNC Symbol;Acc:HGNC:13707] | 6193 | 0.000 | -0.0131 | No |
| 21 | ADCYAP1 | adenylate cyclase activating polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:241] | 7001 | 0.000 | -0.0349 | No |
| 22 | ART3 | ADP-ribosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:725] | 7108 | 0.000 | -0.0378 | No |
| 23 | CCNA1 | cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577] | 7212 | 0.000 | -0.0405 | No |
| 24 | ZC2HC1C | zinc finger C2HC-type containing 1C [Source:HGNC Symbol;Acc:HGNC:20354] | 7909 | 0.000 | -0.0594 | No |
| 25 | HOXB1 | homeobox B1 [Source:HGNC Symbol;Acc:HGNC:5111] | 8460 | 0.000 | -0.0743 | No |
| 26 | ADAM2 | ADAM metallopeptidase domain 2 [Source:HGNC Symbol;Acc:HGNC:198] | 8538 | 0.000 | -0.0763 | No |
| 27 | ADAD1 | adenosine deaminase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30713] | 8692 | 0.000 | -0.0805 | No |
| 28 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 8713 | 0.000 | -0.0810 | No |
| 29 | CRISP2 | cysteine rich secretory protein 2 [Source:HGNC Symbol;Acc:HGNC:12024] | 8754 | 0.000 | -0.0821 | No |
| 30 | NPY5R | neuropeptide Y receptor Y5 [Source:HGNC Symbol;Acc:HGNC:7958] | 8761 | 0.000 | -0.0823 | No |
| 31 | DMRT1 | doublesex and mab-3 related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:2934] | 9285 | 0.000 | -0.0964 | No |
| 32 | GSTM3 | glutathione S-transferase mu 3 [Source:HGNC Symbol;Acc:HGNC:4635] | 9380 | 0.000 | -0.0990 | No |
| 33 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 9678 | 0.000 | -0.1070 | No |
| 34 | TULP2 | TUB like protein 2 [Source:HGNC Symbol;Acc:HGNC:12424] | 9849 | 0.000 | -0.1116 | No |
| 35 | CFTR | CF transmembrane conductance regulator [Source:HGNC Symbol;Acc:HGNC:1884] | 9883 | 0.000 | -0.1125 | No |
| 36 | LDHC | lactate dehydrogenase C [Source:HGNC Symbol;Acc:HGNC:6544] | 10821 | 0.000 | -0.1378 | No |
| 37 | PRM2 | protamine 2 [Source:HGNC Symbol;Acc:HGNC:9448] | 11279 | 0.000 | -0.1502 | No |
| 38 | SEPTIN4 | septin 4 [Source:HGNC Symbol;Acc:HGNC:9165] | 11458 | 0.000 | -0.1550 | No |
| 39 | JAM3 | junctional adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:15532] | 11810 | 0.000 | -0.1645 | No |
| 40 | MEP1B | meprin A subunit beta [Source:HGNC Symbol;Acc:HGNC:7020] | 12210 | 0.000 | -0.1753 | No |
| 41 | THEG | theg spermatid protein [Source:HGNC Symbol;Acc:HGNC:13706] | 12559 | 0.000 | -0.1847 | No |
| 42 | TCP11 | t-complex 11 [Source:HGNC Symbol;Acc:HGNC:11658] | 14288 | 0.000 | -0.2315 | No |
| 43 | TNP2 | transition protein 2 [Source:HGNC Symbol;Acc:HGNC:11952] | 14806 | 0.000 | -0.2455 | No |
| 44 | TNP1 | transition protein 1 [Source:HGNC Symbol;Acc:HGNC:11951] | 14808 | 0.000 | -0.2455 | No |
| 45 | HTR5A | 5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300] | 15547 | 0.000 | -0.2655 | No |
| 46 | CLVS1 | clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139] | 15671 | 0.000 | -0.2688 | No |
| 47 | MTNR1A | melatonin receptor 1A [Source:HGNC Symbol;Acc:HGNC:7463] | 15753 | 0.000 | -0.2710 | No |
| 48 | DCC | DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701] | 15946 | 0.000 | -0.2762 | No |
| 49 | ACTL7B | actin like 7B [Source:HGNC Symbol;Acc:HGNC:162] | 16023 | 0.000 | -0.2783 | No |
| 50 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 16314 | 0.000 | -0.2861 | No |
| 51 | GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [Source:HGNC Symbol;Acc:HGNC:24864] | 16417 | 0.000 | -0.2889 | No |
| 52 | AKAP4 | A-kinase anchoring protein 4 [Source:HGNC Symbol;Acc:HGNC:374] | 16572 | 0.000 | -0.2930 | No |
| 53 | DMC1 | DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927] | 16839 | 0.000 | -0.3002 | No |
| 54 | TKTL1 | transketolase like 1 [Source:HGNC Symbol;Acc:HGNC:11835] | 17164 | 0.000 | -0.3090 | No |
| 55 | HBZ | hemoglobin subunit zeta [Source:HGNC Symbol;Acc:HGNC:4835] | 17211 | 0.000 | -0.3102 | No |
| 56 | SYCP1 | synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487] | 17792 | 0.000 | -0.3259 | No |
| 57 | DNAJB8 | DnaJ heat shock protein family (Hsp40) member B8 [Source:HGNC Symbol;Acc:HGNC:23699] | 18445 | 0.000 | -0.3436 | No |
| 58 | IL12RB2 | interleukin 12 receptor subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:5972] | 19548 | 0.000 | -0.3734 | No |
| 59 | PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor [Source:HGNC Symbol;Acc:HGNC:17301] | 20706 | 0.000 | -0.4047 | No |
| 60 | SHE | Src homology 2 domain containing E [Source:HGNC Symbol;Acc:HGNC:27004] | 20822 | 0.000 | -0.4078 | No |
| 61 | H1-6 | H1.6 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4720] | 22678 | 0.000 | -0.4580 | No |
| 62 | DDX25 | DEAD-box helicase 25 [Source:HGNC Symbol;Acc:HGNC:18698] | 23038 | 0.000 | -0.4677 | No |
| 63 | ACRV1 | acrosomal vesicle protein 1 [Source:HGNC Symbol;Acc:HGNC:127] | 23275 | 0.000 | -0.4741 | No |
| 64 | TSSK2 | testis specific serine kinase 2 [Source:HGNC Symbol;Acc:HGNC:11401] | 24424 | 0.000 | -0.5052 | No |
| 65 | SNAP91 | synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986] | 24554 | 0.000 | -0.5087 | No |
| 66 | CST8 | cystatin 8 [Source:HGNC Symbol;Acc:HGNC:2480] | 24590 | 0.000 | -0.5096 | No |
| 67 | ODF1 | outer dense fiber of sperm tails 1 [Source:HGNC Symbol;Acc:HGNC:8113] | 26269 | 0.000 | -0.5550 | No |
| 68 | ZNRF4 | zinc and ring finger 4 [Source:HGNC Symbol;Acc:HGNC:17726] | 26306 | 0.000 | -0.5560 | No |
| 69 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 26972 | 0.000 | -0.5740 | No |
| 70 | MAP7 | microtubule associated protein 7 [Source:HGNC Symbol;Acc:HGNC:6869] | 27259 | 0.000 | -0.5817 | No |
| 71 | SLC2A5 | solute carrier family 2 member 5 [Source:HGNC Symbol;Acc:HGNC:11010] | 27338 | 0.000 | -0.5838 | No |
| 72 | NAA11 | N-alpha-acetyltransferase 11, NatA catalytic subunit [Source:HGNC Symbol;Acc:HGNC:28125] | 27472 | -0.020 | -0.5872 | No |
| 73 | PEBP1 | phosphatidylethanolamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8630] | 27710 | -0.063 | -0.5930 | No |
| 74 | NEFH | neurofilament heavy [Source:HGNC Symbol;Acc:HGNC:7737] | 27810 | -0.079 | -0.5949 | No |
| 75 | CLGN | calmegin [Source:HGNC Symbol;Acc:HGNC:2060] | 28006 | -0.104 | -0.5991 | No |
| 76 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 28095 | -0.119 | -0.6003 | No |
| 77 | TALDO1 | transaldolase 1 [Source:HGNC Symbol;Acc:HGNC:11559] | 28096 | -0.119 | -0.5991 | No |
| 78 | PHF7 | PHD finger protein 7 [Source:HGNC Symbol;Acc:HGNC:18458] | 28198 | -0.134 | -0.6005 | No |
| 79 | PACRG | parkin coregulated [Source:HGNC Symbol;Acc:HGNC:19152] | 28376 | -0.162 | -0.6037 | No |
| 80 | DDX4 | DEAD-box helicase 4 [Source:HGNC Symbol;Acc:HGNC:18700] | 28409 | -0.165 | -0.6029 | No |
| 81 | GAD1 | glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092] | 28915 | -0.235 | -0.6142 | No |
| 82 | IP6K1 | inositol hexakisphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:18360] | 29012 | -0.251 | -0.6143 | No |
| 83 | BRAF | B-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1097] | 29169 | -0.276 | -0.6157 | No |
| 84 | VDAC3 | voltage dependent anion channel 3 [Source:HGNC Symbol;Acc:HGNC:12674] | 30055 | -0.406 | -0.6356 | No |
| 85 | COIL | coilin [Source:HGNC Symbol;Acc:HGNC:2184] | 30236 | -0.436 | -0.6361 | No |
| 86 | PHKG2 | phosphorylase kinase catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:8931] | 30295 | -0.445 | -0.6332 | No |
| 87 | YBX2 | Y-box binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17948] | 30353 | -0.453 | -0.6301 | No |
| 88 | MTOR | mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942] | 30676 | -0.506 | -0.6338 | No |
| 89 | POMC | proopiomelanocortin [Source:HGNC Symbol;Acc:HGNC:9201] | 31117 | -0.580 | -0.6398 | Yes |
| 90 | ZPBP | zona pellucida binding protein [Source:HGNC Symbol;Acc:HGNC:15662] | 31202 | -0.596 | -0.6361 | Yes |
| 91 | CLPB | caseinolytic mitochondrial matrix peptidase chaperone subunit B [Source:HGNC Symbol;Acc:HGNC:30664] | 31281 | -0.607 | -0.6321 | Yes |
| 92 | PSMG1 | proteasome assembly chaperone 1 [Source:HGNC Symbol;Acc:HGNC:3043] | 31442 | -0.640 | -0.6300 | Yes |
| 93 | PDHA2 | pyruvate dehydrogenase E1 subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8807] | 31620 | -0.674 | -0.6280 | Yes |
| 94 | SIRT1 | sirtuin 1 [Source:HGNC Symbol;Acc:HGNC:14929] | 32019 | -0.758 | -0.6312 | Yes |
| 95 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 32041 | -0.764 | -0.6241 | Yes |
| 96 | ACRBP | acrosin binding protein [Source:HGNC Symbol;Acc:HGNC:17195] | 32133 | -0.788 | -0.6186 | Yes |
| 97 | TNNI3 | troponin I3, cardiac type [Source:HGNC Symbol;Acc:HGNC:11947] | 32349 | -0.849 | -0.6159 | Yes |
| 98 | GFI1 | growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237] | 32393 | -0.863 | -0.6084 | Yes |
| 99 | MAST2 | microtubule associated serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:19035] | 32481 | -0.883 | -0.6019 | Yes |
| 100 | MLLT10 | MLLT10 histone lysine methyltransferase DOT1L cofactor [Source:HGNC Symbol;Acc:HGNC:16063] | 32624 | -0.924 | -0.5964 | Yes |
| 101 | NOS1 | nitric oxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:7872] | 32647 | -0.929 | -0.5877 | Yes |
| 102 | HSPA2 | heat shock protein family A (Hsp70) member 2 [Source:HGNC Symbol;Acc:HGNC:5235] | 32932 | -1.016 | -0.5852 | Yes |
| 103 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 33227 | -1.104 | -0.5820 | Yes |
| 104 | PGK2 | phosphoglycerate kinase 2 [Source:HGNC Symbol;Acc:HGNC:8898] | 33300 | -1.126 | -0.5726 | Yes |
| 105 | PCSK4 | proprotein convertase subtilisin/kexin type 4 [Source:HGNC Symbol;Acc:HGNC:8746] | 33353 | -1.144 | -0.5625 | Yes |
| 106 | TUBA3C | tubulin alpha 3c [Source:HGNC Symbol;Acc:HGNC:12408] | 33611 | -1.235 | -0.5571 | Yes |
| 107 | GSG1 | germ cell associated 1 [Source:HGNC Symbol;Acc:HGNC:19716] | 33667 | -1.255 | -0.5460 | Yes |
| 108 | PARP2 | poly(ADP-ribose) polymerase 2 [Source:HGNC Symbol;Acc:HGNC:272] | 33694 | -1.264 | -0.5340 | Yes |
| 109 | CHFR | checkpoint with forkhead and ring finger domains [Source:HGNC Symbol;Acc:HGNC:20455] | 33750 | -1.282 | -0.5226 | Yes |
| 110 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 33968 | -1.361 | -0.5148 | Yes |
| 111 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 34274 | -1.478 | -0.5082 | Yes |
| 112 | LPIN1 | lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345] | 34304 | -1.489 | -0.4940 | Yes |
| 113 | IDE | insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381] | 34342 | -1.505 | -0.4798 | Yes |
| 114 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34381 | -1.518 | -0.4656 | Yes |
| 115 | MLF1 | myeloid leukemia factor 1 [Source:HGNC Symbol;Acc:HGNC:7125] | 34406 | -1.529 | -0.4509 | Yes |
| 116 | NF2 | neurofibromin 2 [Source:HGNC Symbol;Acc:HGNC:7773] | 34618 | -1.611 | -0.4404 | Yes |
| 117 | ZC3H14 | zinc finger CCCH-type containing 14 [Source:HGNC Symbol;Acc:HGNC:20509] | 34631 | -1.615 | -0.4245 | Yes |
| 118 | PRKAR2A | protein kinase cAMP-dependent type II regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9391] | 34709 | -1.653 | -0.4100 | Yes |
| 119 | HSPA4L | heat shock protein family A (Hsp70) member 4 like [Source:HGNC Symbol;Acc:HGNC:17041] | 34953 | -1.775 | -0.3987 | Yes |
| 120 | IFT88 | intraflagellar transport 88 [Source:HGNC Symbol;Acc:HGNC:20606] | 35260 | -1.969 | -0.3872 | Yes |
| 121 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35380 | -2.050 | -0.3698 | Yes |
| 122 | NPHP1 | nephrocystin 1 [Source:HGNC Symbol;Acc:HGNC:7905] | 35620 | -2.211 | -0.3541 | Yes |
| 123 | TOPBP1 | DNA topoisomerase II binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17008] | 35809 | -2.377 | -0.3353 | Yes |
| 124 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35813 | -2.385 | -0.3114 | Yes |
| 125 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35830 | -2.402 | -0.2877 | Yes |
| 126 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36065 | -2.624 | -0.2676 | Yes |
| 127 | STRBP | spermatid perinuclear RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16462] | 36071 | -2.628 | -0.2413 | Yes |
| 128 | GMCL1 | germ cell-less 1, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:23843] | 36227 | -2.779 | -0.2176 | Yes |
| 129 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 36273 | -2.821 | -0.1905 | Yes |
| 130 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36367 | -2.940 | -0.1634 | Yes |
| 131 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36546 | -3.187 | -0.1362 | Yes |
| 132 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36710 | -3.442 | -0.1060 | Yes |
| 133 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36780 | -3.580 | -0.0719 | Yes |
| 134 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36841 | -3.749 | -0.0359 | Yes |
| 135 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 37006 | -4.236 | 0.0023 | Yes |
