Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | CHR17Q12 |
| Enrichment Score (ES) | 0.47230306 |
| Normalized Enrichment Score (NES) | 1.221404 |
| Nominal p-value | 0.013605442 |
| FDR q-value | 0.53512484 |
| FWER p-Value | 0.979 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 20 | 4.911 | 0.0453 | Yes |
| 2 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 56 | 4.661 | 0.0879 | Yes |
| 3 | SLFN5 | schlafen family member 5 [Source:HGNC Symbol;Acc:HGNC:28286] | 120 | 4.257 | 0.1260 | Yes |
| 4 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 155 | 4.115 | 0.1635 | Yes |
| 5 | SLFN11 | schlafen family member 11 [Source:HGNC Symbol;Acc:HGNC:26633] | 222 | 3.792 | 0.1971 | Yes |
| 6 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 339 | 3.424 | 0.2259 | Yes |
| 7 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 413 | 3.159 | 0.2534 | Yes |
| 8 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 616 | 2.675 | 0.2730 | Yes |
| 9 | RFFL | ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821] | 771 | 2.474 | 0.2919 | Yes |
| 10 | E2F3P1 | E2F transcription factor 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:3116] | 860 | 2.334 | 0.3113 | Yes |
| 11 | EPOP | elongin BC and polycomb repressive complex 2 associated protein [Source:HGNC Symbol;Acc:HGNC:34493] | 942 | 2.223 | 0.3299 | Yes |
| 12 | SRCIN1 | SRC kinase signaling inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:29506] | 946 | 2.217 | 0.3505 | Yes |
| 13 | CWC25 | CWC25 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:25989] | 1085 | 2.045 | 0.3659 | Yes |
| 14 | CDK12 | cyclin dependent kinase 12 [Source:HGNC Symbol;Acc:HGNC:24224] | 1673 | 1.578 | 0.3647 | Yes |
| 15 | AP2B1 | adaptor related protein complex 2 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:563] | 1679 | 1.572 | 0.3793 | Yes |
| 16 | TCAP | titin-cap [Source:HGNC Symbol;Acc:HGNC:11610] | 1694 | 1.564 | 0.3935 | Yes |
| 17 | SLFN13 | schlafen family member 13 [Source:HGNC Symbol;Acc:HGNC:26481] | 1842 | 1.469 | 0.4032 | Yes |
| 18 | MYO19 | myosin XIX [Source:HGNC Symbol;Acc:HGNC:26234] | 2157 | 1.261 | 0.4065 | Yes |
| 19 | ZNHIT3 | zinc finger HIT-type containing 3 [Source:HGNC Symbol;Acc:HGNC:12309] | 2192 | 1.241 | 0.4172 | Yes |
| 20 | PEX12 | peroxisomal biogenesis factor 12 [Source:HGNC Symbol;Acc:HGNC:8854] | 2258 | 1.227 | 0.4269 | Yes |
| 21 | STARD3 | StAR related lipid transfer domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17579] | 2374 | 1.179 | 0.4348 | Yes |
| 22 | PGAP3 | post-GPI attachment to proteins phospholipase 3 [Source:HGNC Symbol;Acc:HGNC:23719] | 2392 | 1.172 | 0.4453 | Yes |
| 23 | UNC45B | unc-45 myosin chaperone B [Source:HGNC Symbol;Acc:HGNC:14304] | 2501 | 1.129 | 0.4529 | Yes |
| 24 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 2621 | 1.079 | 0.4598 | Yes |
| 25 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 2744 | 1.028 | 0.4660 | Yes |
| 26 | NLE1 | notchless homolog 1 [Source:HGNC Symbol;Acc:HGNC:19889] | 3115 | 0.876 | 0.4642 | Yes |
| 27 | ZNF830 | zinc finger protein 830 [Source:HGNC Symbol;Acc:HGNC:28291] | 3199 | 0.843 | 0.4698 | Yes |
| 28 | ARHGAP23 | Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:HGNC:29293] | 3665 | 0.689 | 0.4637 | Yes |
| 29 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 3986 | 0.583 | 0.4605 | Yes |
| 30 | AATF | apoptosis antagonizing transcription factor [Source:HGNC Symbol;Acc:HGNC:19235] | 4057 | 0.564 | 0.4639 | Yes |
| 31 | PIGW | phosphatidylinositol glycan anchor biosynthesis class W [Source:HGNC Symbol;Acc:HGNC:23213] | 4107 | 0.547 | 0.4676 | Yes |
| 32 | DHRS11 | dehydrogenase/reductase 11 [Source:HGNC Symbol;Acc:HGNC:28639] | 4123 | 0.543 | 0.4723 | Yes |
| 33 | PSMB3 | proteasome 20S subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:9540] | 4430 | 0.451 | 0.4682 | No |
| 34 | GGNBP2 | gametogenetin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19357] | 4663 | 0.382 | 0.4655 | No |
| 35 | MIEN1 | migration and invasion enhancer 1 [Source:HGNC Symbol;Acc:HGNC:28230] | 6128 | 0.061 | 0.4265 | No |
| 36 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6392 | 0.000 | 0.4194 | No |
| 37 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6393 | 0.000 | 0.4194 | No |
| 38 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6394 | 0.000 | 0.4194 | No |
| 39 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6414 | 0.000 | 0.4188 | No |
| 40 | CCL16 | C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614] | 6417 | 0.000 | 0.4188 | No |
| 41 | CCL15 | C-C motif chemokine ligand 15 [Source:HGNC Symbol;Acc:HGNC:10613] | 6419 | 0.000 | 0.4188 | No |
| 42 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6423 | 0.000 | 0.4187 | No |
| 43 | TBC1D3 | TBC1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:19031] | 7641 | 0.000 | 0.3858 | No |
| 44 | LYZL6 | lysozyme like 6 [Source:HGNC Symbol;Acc:HGNC:29614] | 7965 | 0.000 | 0.3770 | No |
| 45 | ASIC2 | acid sensing ion channel subunit 2 [Source:HGNC Symbol;Acc:HGNC:99] | 8018 | 0.000 | 0.3756 | No |
| 46 | MIR2909 | microRNA 2909 [Source:HGNC Symbol;Acc:HGNC:38372] | 9245 | 0.000 | 0.3424 | No |
| 47 | RASL10B | RAS like family 10 member B [Source:HGNC Symbol;Acc:HGNC:30295] | 9841 | 0.000 | 0.3263 | No |
| 48 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 9913 | 0.000 | 0.3244 | No |
| 49 | AA06 | uncharacterized LOC100506677 [Source:NCBI gene (formerly Entrezgene);Acc:100506677] | 10226 | 0.000 | 0.3160 | No |
| 50 | PNMT | phenylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:9160] | 10624 | 0.000 | 0.3052 | No |
| 51 | C17orf50 | chromosome 17 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:29581] | 11837 | 0.000 | 0.2724 | No |
| 52 | C17orf78 | chromosome 17 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:26831] | 11865 | 0.000 | 0.2717 | No |
| 53 | C17orf98 | chromosome 17 open reading frame 98 [Source:HGNC Symbol;Acc:HGNC:34492] | 11888 | 0.000 | 0.2711 | No |
| 54 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 12139 | 0.000 | 0.2644 | No |
| 55 | SNHG30 | small nucleolar RNA host gene 30 [Source:HGNC Symbol;Acc:HGNC:52836] | 12346 | 0.000 | 0.2588 | No |
| 56 | RNU6-1192P | RNA, U6 small nuclear 1192, pseudogene [Source:HGNC Symbol;Acc:HGNC:48155] | 12907 | 0.000 | 0.2436 | No |
| 57 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14842 | 0.000 | 0.1913 | No |
| 58 | SLC35G3 | solute carrier family 35 member G3 [Source:HGNC Symbol;Acc:HGNC:26848] | 15929 | 0.000 | 0.1619 | No |
| 59 | RN7SL301P | RNA, 7SL, cytoplasmic 301, pseudogene [Source:HGNC Symbol;Acc:HGNC:46317] | 16010 | 0.000 | 0.1598 | No |
| 60 | SNORA21 | small nucleolar RNA, H/ACA box 21 [Source:HGNC Symbol;Acc:HGNC:32611] | 16088 | 0.000 | 0.1577 | No |
| 61 | C17orf102 | chromosome 17 open reading frame 102 [Source:HGNC Symbol;Acc:HGNC:34412] | 16596 | 0.000 | 0.1440 | No |
| 62 | RNU6-866P | RNA, U6 small nuclear 866, pseudogene [Source:HGNC Symbol;Acc:HGNC:47829] | 17100 | 0.000 | 0.1303 | No |
| 63 | RNA5SP440 | RNA, 5S ribosomal pseudogene 440 [Source:HGNC Symbol;Acc:HGNC:43340] | 17336 | 0.000 | 0.1240 | No |
| 64 | RNA5SP439 | RNA, 5S ribosomal pseudogene 439 [Source:HGNC Symbol;Acc:HGNC:43339] | 17372 | 0.000 | 0.1230 | No |
| 65 | RNA5SP438 | RNA, 5S ribosomal pseudogene 438 [Source:HGNC Symbol;Acc:HGNC:43338] | 17373 | 0.000 | 0.1230 | No |
| 66 | CCL15-CCL14 | CCL15-CCL14 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44436] | 17487 | 0.000 | 0.1200 | No |
| 67 | SNORD7 | small nucleolar RNA, C/D box 7 [Source:HGNC Symbol;Acc:HGNC:32704] | 17526 | 0.000 | 0.1189 | No |
| 68 | HNF1B | HNF1 homeobox B [Source:HGNC Symbol;Acc:HGNC:11630] | 17653 | 0.000 | 0.1155 | No |
| 69 | PPP1R1B | protein phosphatase 1 regulatory inhibitor subunit 1B [Source:HGNC Symbol;Acc:HGNC:9287] | 17694 | 0.000 | 0.1145 | No |
| 70 | LRRC37A9P | leucine rich repeat containing 37 member A9, pseudogene [Source:HGNC Symbol;Acc:HGNC:43813] | 17739 | 0.000 | 0.1133 | No |
| 71 | RNU6-489P | RNA, U6 small nuclear 489, pseudogene [Source:HGNC Symbol;Acc:HGNC:47452] | 18561 | 0.000 | 0.0911 | No |
| 72 | RNU6-233P | RNA, U6 small nuclear 233, pseudogene [Source:HGNC Symbol;Acc:HGNC:47196] | 18983 | 0.000 | 0.0797 | No |
| 73 | NEUROD2 | neuronal differentiation 2 [Source:HGNC Symbol;Acc:HGNC:7763] | 19363 | 0.000 | 0.0694 | No |
| 74 | SLFN14 | schlafen family member 14 [Source:HGNC Symbol;Acc:HGNC:32689] | 20127 | 0.000 | 0.0488 | No |
| 75 | LHX1 | LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6593] | 20331 | 0.000 | 0.0433 | No |
| 76 | FNDC8 | fibronectin type III domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25286] | 23228 | 0.000 | -0.0351 | No |
| 77 | RNU6-840P | RNA, U6 small nuclear 840, pseudogene [Source:HGNC Symbol;Acc:HGNC:47803] | 23340 | 0.000 | -0.0381 | No |
| 78 | GAS2L2 | growth arrest specific 2 like 2 [Source:HGNC Symbol;Acc:HGNC:24846] | 24211 | 0.000 | -0.0616 | No |
| 79 | MIR4734 | microRNA 4734 [Source:HGNC Symbol;Acc:HGNC:41572] | 24659 | 0.000 | -0.0737 | No |
| 80 | MIR4726 | microRNA 4726 [Source:HGNC Symbol;Acc:HGNC:41722] | 24679 | 0.000 | -0.0742 | No |
| 81 | MIR4728 | microRNA 4728 [Source:HGNC Symbol;Acc:HGNC:41632] | 24682 | 0.000 | -0.0743 | No |
| 82 | MIR4727 | microRNA 4727 [Source:HGNC Symbol;Acc:HGNC:41709] | 24683 | 0.000 | -0.0743 | No |
| 83 | LINC01989 | long intergenic non-protein coding RNA 1989 [Source:HGNC Symbol;Acc:HGNC:52821] | 25167 | 0.000 | -0.0874 | No |
| 84 | HEATR9 | HEAT repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:26548] | 26581 | 0.000 | -0.1256 | No |
| 85 | LINC02079 | long intergenic non-protein coding RNA 2079 [Source:HGNC Symbol;Acc:HGNC:52927] | 26683 | 0.000 | -0.1283 | No |
| 86 | TBC1D3K | TBC1 domain family member 3K [Source:HGNC Symbol;Acc:HGNC:51245] | 27349 | 0.000 | -0.1463 | No |
| 87 | TBC1D3L | TBC1 domain family member 3L [Source:HGNC Symbol;Acc:HGNC:51246] | 27350 | 0.000 | -0.1463 | No |
| 88 | TBC1D3B | TBC1 domain family member 3B [Source:HGNC Symbol;Acc:HGNC:27011] | 27356 | 0.000 | -0.1465 | No |
| 89 | TBC1D3E | TBC1 domain family member 3E [Source:HGNC Symbol;Acc:HGNC:27071] | 27358 | 0.000 | -0.1465 | No |
| 90 | TBC1D3F | TBC1 domain family member 3F [Source:HGNC Symbol;Acc:HGNC:18257] | 27359 | 0.000 | -0.1465 | No |
| 91 | TBC1D3C | TBC1 domain family member 3C [Source:HGNC Symbol;Acc:HGNC:24889] | 27361 | 0.000 | -0.1465 | No |
| 92 | TBC1D3D | TBC1 domain family member 3D [Source:HGNC Symbol;Acc:HGNC:28944] | 27362 | 0.000 | -0.1465 | No |
| 93 | TBC1D3I | TBC1 domain family member 3I [Source:HGNC Symbol;Acc:HGNC:32709] | 27363 | 0.000 | -0.1465 | No |
| 94 | TBC1D3J | TBC1 domain family member 3J [Source:HGNC Symbol;Acc:HGNC:51247] | 27365 | 0.000 | -0.1465 | No |
| 95 | TBC1D3G | TBC1 domain family member 3G [Source:HGNC Symbol;Acc:HGNC:29860] | 27367 | 0.000 | -0.1466 | No |
| 96 | TBC1D3H | TBC1 domain family member 3H [Source:HGNC Symbol;Acc:HGNC:30708] | 27368 | 0.000 | -0.1466 | No |
| 97 | TMEM132E | transmembrane protein 132E [Source:HGNC Symbol;Acc:HGNC:26991] | 27620 | 0.000 | -0.1534 | No |
| 98 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 28028 | 0.000 | -0.1644 | No |
| 99 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 28030 | 0.000 | -0.1644 | No |
| 100 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 28037 | 0.000 | -0.1646 | No |
| 101 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 28039 | 0.000 | -0.1646 | No |
| 102 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 28040 | 0.000 | -0.1646 | No |
| 103 | LRRC37A11P | leucine rich repeat containing 37 member A11, pseudogene [Source:HGNC Symbol;Acc:HGNC:43815] | 28517 | 0.000 | -0.1775 | No |
| 104 | YWHAEP7 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:49437] | 28578 | -0.016 | -0.1789 | No |
| 105 | FBXO47 | F-box protein 47 [Source:HGNC Symbol;Acc:HGNC:31969] | 28882 | -0.095 | -0.1862 | No |
| 106 | ARL5C | ADP ribosylation factor like GTPase 5C [Source:HGNC Symbol;Acc:HGNC:31111] | 28965 | -0.114 | -0.1874 | No |
| 107 | SYNRG | synergin gamma [Source:HGNC Symbol;Acc:HGNC:557] | 29104 | -0.147 | -0.1898 | No |
| 108 | SOCS7 | suppressor of cytokine signaling 7 [Source:HGNC Symbol;Acc:HGNC:29846] | 29220 | -0.179 | -0.1912 | No |
| 109 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 29267 | -0.190 | -0.1907 | No |
| 110 | RPL19 | ribosomal protein L19 [Source:HGNC Symbol;Acc:HGNC:10312] | 29530 | -0.247 | -0.1955 | No |
| 111 | RPL23 | ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316] | 30008 | -0.357 | -0.2050 | No |
| 112 | LIG3 | DNA ligase 3 [Source:HGNC Symbol;Acc:HGNC:6600] | 30781 | -0.562 | -0.2207 | No |
| 113 | HMGB1P24 | high mobility group box 1 pseudogene 24 [Source:HGNC Symbol;Acc:HGNC:39115] | 30862 | -0.583 | -0.2174 | No |
| 114 | MLLT6 | MLLT6, PHD finger containing [Source:HGNC Symbol;Acc:HGNC:7138] | 30893 | -0.589 | -0.2127 | No |
| 115 | MRM1 | mitochondrial rRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26202] | 31707 | -0.805 | -0.2272 | No |
| 116 | PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase type 2 beta [Source:HGNC Symbol;Acc:HGNC:8998] | 31765 | -0.826 | -0.2210 | No |
| 117 | CISD3 | CDGSH iron sulfur domain 3 [Source:HGNC Symbol;Acc:HGNC:27578] | 32191 | -0.982 | -0.2233 | No |
| 118 | ACACA | acetyl-CoA carboxylase alpha [Source:HGNC Symbol;Acc:HGNC:84] | 32380 | -1.035 | -0.2188 | No |
| 119 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 33112 | -1.295 | -0.2265 | No |
| 120 | RAD51D | RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823] | 34019 | -1.630 | -0.2357 | No |
| 121 | DDX52 | DExD-box helicase 52 [Source:HGNC Symbol;Acc:HGNC:20038] | 34059 | -1.646 | -0.2214 | No |
| 122 | TOMM20P2 | TOMM20 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:50519] | 34891 | -2.105 | -0.2242 | No |
| 123 | LINC00672 | long intergenic non-protein coding RNA 672 [Source:HGNC Symbol;Acc:HGNC:44353] | 35248 | -2.316 | -0.2122 | No |
| 124 | PCGF2 | polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929] | 35406 | -2.396 | -0.1941 | No |
| 125 | GPR179 | G protein-coupled receptor 179 [Source:HGNC Symbol;Acc:HGNC:31371] | 35499 | -2.471 | -0.1735 | No |
| 126 | TADA2A | transcriptional adaptor 2A [Source:HGNC Symbol;Acc:HGNC:11531] | 35543 | -2.518 | -0.1512 | No |
| 127 | RDM1 | RAD52 motif containing 1 [Source:HGNC Symbol;Acc:HGNC:19950] | 35616 | -2.578 | -0.1291 | No |
| 128 | MMP28 | matrix metallopeptidase 28 [Source:HGNC Symbol;Acc:HGNC:14366] | 36158 | -3.114 | -0.1146 | No |
| 129 | FBXL20 | F-box and leucine rich repeat protein 20 [Source:HGNC Symbol;Acc:HGNC:24679] | 36308 | -3.248 | -0.0883 | No |
| 130 | STAC2 | SH3 and cysteine rich domain 2 [Source:HGNC Symbol;Acc:HGNC:23990] | 36719 | -3.853 | -0.0634 | No |
| 131 | CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:1401] | 36723 | -3.858 | -0.0275 | No |
| 132 | PLXDC1 | plexin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20945] | 36797 | -4.003 | 0.0079 | No |
