Fig 1: Enrichment plot: CHR4Q25
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | CHR4Q25 |
| Enrichment Score (ES) | -0.6051872 |
| Normalized Enrichment Score (NES) | -1.2458303 |
| Nominal p-value | 0.09398496 |
| FDR q-value | 0.91356665 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAR1 | GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14264] | 931 | 2.240 | 0.0191 | No |
| 2 | LEF1 | lymphoid enhancer binding factor 1 [Source:HGNC Symbol;Acc:HGNC:6551] | 1452 | 1.743 | 0.0394 | No |
| 3 | RAC1P5 | Rac family small GTPase 1 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:30593] | 1656 | 1.584 | 0.0652 | No |
| 4 | TOX4P1 | TOX high mobility group box family member 4 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44009] | 1941 | 1.390 | 0.0850 | No |
| 5 | LARP7 | La ribonucleoprotein 7, transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:24912] | 2606 | 1.083 | 0.0884 | No |
| 6 | SEC24B | SEC24 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10704] | 2717 | 1.042 | 0.1060 | No |
| 7 | RBMXP4 | RBMX pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:34028] | 3486 | 0.743 | 0.0999 | No |
| 8 | OSTC | oligosaccharyltransferase complex non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:24448] | 4104 | 0.548 | 0.0941 | No |
| 9 | LYPLA1P2 | LYPLA1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:44006] | 4380 | 0.469 | 0.0959 | No |
| 10 | AP1AR | adaptor related protein complex 1 associated regulatory protein [Source:HGNC Symbol;Acc:HGNC:28808] | 4447 | 0.444 | 0.1029 | No |
| 11 | FAM241A | family with sequence similarity 241 member A [Source:HGNC Symbol;Acc:HGNC:26813] | 5236 | 0.239 | 0.0863 | No |
| 12 | SETP20 | SET pseudogene 20 [Source:HGNC Symbol;Acc:HGNC:42939] | 5397 | 0.239 | 0.0867 | No |
| 13 | COL25A1 | collagen type XXV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:18603] | 6499 | 0.000 | 0.0569 | No |
| 14 | ETNPPL | ethanolamine-phosphate phospho-lyase [Source:HGNC Symbol;Acc:HGNC:14404] | 6561 | 0.000 | 0.0553 | No |
| 15 | LINC01438 | long intergenic non-protein coding RNA 1438 [Source:HGNC Symbol;Acc:HGNC:50757] | 6850 | 0.000 | 0.0475 | No |
| 16 | PITX2 | paired like homeodomain 2 [Source:HGNC Symbol;Acc:HGNC:9005] | 7420 | 0.000 | 0.0321 | No |
| 17 | ZNF969P | zinc finger protein 969, pseudogene [Source:HGNC Symbol;Acc:HGNC:44211] | 8947 | 0.000 | -0.0091 | No |
| 18 | KRT19P3 | keratin 19 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:33424] | 10571 | 0.000 | -0.0529 | No |
| 19 | RNU6-551P | RNA, U6 small nuclear 551, pseudogene [Source:HGNC Symbol;Acc:HGNC:47514] | 10744 | 0.000 | -0.0576 | No |
| 20 | RNU6-733P | RNA, U6 small nuclear 733, pseudogene [Source:HGNC Symbol;Acc:HGNC:47696] | 11181 | 0.000 | -0.0694 | No |
| 21 | HIGD1AP14 | HIG1 hypoxia inducible domain family member 1A pseudogene 14 [Source:HGNC Symbol;Acc:HGNC:43009] | 13438 | 0.000 | -0.1303 | No |
| 22 | LRIT3 | leucine rich repeat, Ig-like and transmembrane domains 3 [Source:HGNC Symbol;Acc:HGNC:24783] | 14588 | 0.000 | -0.1613 | No |
| 23 | RNU6-289P | RNA, U6 small nuclear 289, pseudogene [Source:HGNC Symbol;Acc:HGNC:47252] | 15043 | 0.000 | -0.1736 | No |
| 24 | ZACNP1 | zinc activated ion channel pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:51915] | 15137 | 0.000 | -0.1761 | No |
| 25 | SEC24B-AS1 | SEC24B antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44003] | 15346 | 0.000 | -0.1817 | No |
| 26 | CFI | complement factor I [Source:HGNC Symbol;Acc:HGNC:5394] | 15762 | 0.000 | -0.1929 | No |
| 27 | DKK2 | dickkopf WNT signaling pathway inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:2892] | 16372 | 0.000 | -0.2094 | No |
| 28 | SGMS2 | sphingomyelin synthase 2 [Source:HGNC Symbol;Acc:HGNC:28395] | 17192 | 0.000 | -0.2315 | No |
| 29 | PANCR | PITX2 adjacent non-coding RNA [Source:HGNC Symbol;Acc:HGNC:52282] | 17213 | 0.000 | -0.2321 | No |
| 30 | RPL7L1P13 | ribosomal protein L7 like 1 pseudogene 13 [Source:HGNC Symbol;Acc:HGNC:44212] | 18353 | 0.000 | -0.2628 | No |
| 31 | OSTCP4 | oligosaccharyltransferase complex subunit pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:42866] | 18864 | 0.000 | -0.2766 | No |
| 32 | NEUROG2 | neurogenin 2 [Source:HGNC Symbol;Acc:HGNC:13805] | 19476 | 0.000 | -0.2931 | No |
| 33 | RNU6-431P | RNA, U6 small nuclear 431, pseudogene [Source:HGNC Symbol;Acc:HGNC:47394] | 19718 | 0.000 | -0.2996 | No |
| 34 | ZBED1P1 | zinc finger BED-type containing 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44004] | 20183 | 0.000 | -0.3122 | No |
| 35 | RN7SL275P | RNA, 7SL, cytoplasmic 275, pseudogene [Source:HGNC Symbol;Acc:HGNC:46291] | 20619 | 0.000 | -0.3239 | No |
| 36 | COL25A1-DT | COL25A1 divergent transcript [Source:HGNC Symbol;Acc:HGNC:32963] | 21609 | 0.000 | -0.3506 | No |
| 37 | LEF1-AS1 | LEF1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40339] | 23379 | 0.000 | -0.3984 | No |
| 38 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 24542 | 0.000 | -0.4298 | No |
| 39 | RN7SL55P | RNA, 7SL, cytoplasmic 55, pseudogene [Source:HGNC Symbol;Acc:HGNC:46071] | 24883 | 0.000 | -0.4390 | No |
| 40 | RNU6-205P | RNA, U6 small nuclear 205, pseudogene [Source:HGNC Symbol;Acc:HGNC:47168] | 25187 | 0.000 | -0.4472 | No |
| 41 | RRH | retinal pigment epithelium-derived rhodopsin homolog [Source:HGNC Symbol;Acc:HGNC:10450] | 25439 | 0.000 | -0.4540 | No |
| 42 | WRBP1 | tryptophan rich basic protein pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44010] | 25634 | 0.000 | -0.4592 | No |
| 43 | MIR302D | microRNA 302d [Source:HGNC Symbol;Acc:HGNC:31765] | 25770 | 0.000 | -0.4629 | No |
| 44 | MIR302C | microRNA 302c [Source:HGNC Symbol;Acc:HGNC:31764] | 25772 | 0.000 | -0.4629 | No |
| 45 | MIR302A | microRNA 302a [Source:HGNC Symbol;Acc:HGNC:31623] | 25774 | 0.000 | -0.4629 | No |
| 46 | MIR297 | microRNA 297 [Source:HGNC Symbol;Acc:HGNC:33691] | 25829 | 0.000 | -0.4644 | No |
| 47 | RPL34-DT | RPL34 divergent transcript [Source:HGNC Symbol;Acc:HGNC:26749] | 25930 | 0.000 | -0.4671 | No |
| 48 | HSBP1P2 | heat shock factor binding protein 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:37300] | 26119 | 0.000 | -0.4721 | No |
| 49 | MIR576 | microRNA 576 [Source:HGNC Symbol;Acc:HGNC:32832] | 26299 | 0.000 | -0.4770 | No |
| 50 | ACTR6P1 | ACTR6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44210] | 26726 | 0.000 | -0.4885 | No |
| 51 | CCDC34P1 | coiled-coil domain containing 34 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44008] | 26865 | 0.000 | -0.4922 | No |
| 52 | MIR367 | microRNA 367 [Source:HGNC Symbol;Acc:HGNC:31781] | 27095 | 0.000 | -0.4984 | No |
| 53 | RNU6-35P | RNA, U6 small nuclear 35, pseudogene [Source:HGNC Symbol;Acc:HGNC:34279] | 27328 | 0.000 | -0.5047 | No |
| 54 | RPSAP34 | ribosomal protein SA pseudogene 34 [Source:HGNC Symbol;Acc:HGNC:36643] | 27552 | 0.000 | -0.5107 | No |
| 55 | RPL7AP30 | ribosomal protein L7a pseudogene 30 [Source:HGNC Symbol;Acc:HGNC:35757] | 29644 | -0.275 | -0.5617 | No |
| 56 | RPL34 | ribosomal protein L34 [Source:HGNC Symbol;Acc:HGNC:10340] | 29731 | -0.298 | -0.5582 | No |
| 57 | TUBB8P3 | tubulin beta 8 class VIII pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:42338] | 31083 | -0.639 | -0.5821 | No |
| 58 | ANK2 | ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493] | 31940 | -0.892 | -0.5876 | Yes |
| 59 | RPL23AP94 | ribosomal protein L23a pseudogene 94 [Source:HGNC Symbol;Acc:HGNC:51629] | 32313 | -1.023 | -0.5774 | Yes |
| 60 | RCC2P8 | regulator of chromosome condensation 2 pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:42384] | 32648 | -1.132 | -0.5641 | Yes |
| 61 | MCUB | mitochondrial calcium uniporter dominant negative subunit beta [Source:HGNC Symbol;Acc:HGNC:26076] | 32708 | -1.150 | -0.5430 | Yes |
| 62 | CYP2U1 | cytochrome P450 family 2 subfamily U member 1 [Source:HGNC Symbol;Acc:HGNC:20582] | 33062 | -1.279 | -0.5273 | Yes |
| 63 | RTEL1P1 | regulator of telomere elongation helicase 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44213] | 33184 | -1.326 | -0.5044 | Yes |
| 64 | ALPK1 | alpha kinase 1 [Source:HGNC Symbol;Acc:HGNC:20917] | 33235 | -1.351 | -0.4791 | Yes |
| 65 | CASP6 | caspase 6 [Source:HGNC Symbol;Acc:HGNC:1507] | 34349 | -1.786 | -0.4739 | Yes |
| 66 | ZGRF1 | zinc finger GRF-type containing 1 [Source:HGNC Symbol;Acc:HGNC:25654] | 34466 | -1.841 | -0.4407 | Yes |
| 67 | CDC42P4 | cell division cycle 42 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:44428] | 35331 | -2.332 | -0.4180 | Yes |
| 68 | EGF | epidermal growth factor [Source:HGNC Symbol;Acc:HGNC:3229] | 35525 | -2.501 | -0.3739 | Yes |
| 69 | EXOC7P1 | exocyst complex component 7 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:43871] | 35590 | -2.555 | -0.3252 | Yes |
| 70 | ELOVL6 | ELOVL fatty acid elongase 6 [Source:HGNC Symbol;Acc:HGNC:15829] | 35985 | -2.910 | -0.2784 | Yes |
| 71 | PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [Source:HGNC Symbol;Acc:HGNC:8603] | 36403 | -3.391 | -0.2227 | Yes |
| 72 | HADH | hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799] | 36680 | -3.784 | -0.1555 | Yes |
| 73 | TIFA | TRAF interacting protein with forkhead associated domain [Source:HGNC Symbol;Acc:HGNC:19075] | 36832 | -4.051 | -0.0796 | Yes |
| 74 | PLA2G12A | phospholipase A2 group XIIA [Source:HGNC Symbol;Acc:HGNC:18554] | 36958 | -4.387 | 0.0036 | Yes |
