Fig 1: Enrichment plot: CHR6Q14
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | CHR6Q14 |
| Enrichment Score (ES) | -0.66762847 |
| Normalized Enrichment Score (NES) | -1.3983986 |
| Nominal p-value | 0.014563107 |
| FDR q-value | 0.36312455 |
| FWER p-Value | 0.939 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SYNCRIP | synaptotagmin binding cytoplasmic RNA interacting protein [Source:HGNC Symbol;Acc:HGNC:16918] | 2182 | 1.247 | -0.0317 | No |
| 2 | ME1 | malic enzyme 1 [Source:HGNC Symbol;Acc:HGNC:6983] | 2580 | 1.097 | -0.0185 | No |
| 3 | SH3BGRL2 | SH3 domain binding glutamate rich protein like 2 [Source:HGNC Symbol;Acc:HGNC:15567] | 2693 | 1.051 | 0.0014 | No |
| 4 | TENT5A | terminal nucleotidyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:18345] | 2967 | 0.944 | 0.0147 | No |
| 5 | SENP6 | SUMO specific peptidase 6 [Source:HGNC Symbol;Acc:HGNC:20944] | 3371 | 0.785 | 0.0209 | No |
| 6 | ZNF292 | zinc finger protein 292 [Source:HGNC Symbol;Acc:HGNC:18410] | 4484 | 0.436 | 0.0004 | No |
| 7 | CYB5R4 | cytochrome b5 reductase 4 [Source:HGNC Symbol;Acc:HGNC:20147] | 4533 | 0.421 | 0.0083 | No |
| 8 | TPBG | trophoblast glycoprotein [Source:HGNC Symbol;Acc:HGNC:12004] | 4964 | 0.301 | 0.0032 | No |
| 9 | SMARCE1P2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:39732] | 5331 | 0.239 | -0.0014 | No |
| 10 | IBTK | inhibitor of Bruton tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:17853] | 5706 | 0.188 | -0.0074 | No |
| 11 | COL12A1 | collagen type XII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2188] | 5848 | 0.146 | -0.0081 | No |
| 12 | COX7A2 | cytochrome c oxidase subunit 7A2 [Source:HGNC Symbol;Acc:HGNC:2288] | 6103 | 0.068 | -0.0134 | No |
| 13 | PRSS35 | serine protease 35 [Source:HGNC Symbol;Acc:HGNC:21387] | 6430 | 0.000 | -0.0222 | No |
| 14 | LINC01621 | long intergenic non-protein coding RNA 1621 [Source:HGNC Symbol;Acc:HGNC:14109] | 7301 | 0.000 | -0.0457 | No |
| 15 | LINC01611 | long intergenic non-protein coding RNA 1611 [Source:HGNC Symbol;Acc:HGNC:51791] | 7324 | 0.000 | -0.0463 | No |
| 16 | LINC01526 | long intergenic non-protein coding RNA 1526 [Source:HGNC Symbol;Acc:HGNC:51265] | 7696 | 0.000 | -0.0564 | No |
| 17 | RNU6-130P | RNA, U6 small nuclear 130, pseudogene [Source:HGNC Symbol;Acc:HGNC:47093] | 8485 | 0.000 | -0.0777 | No |
| 18 | RNU6-155P | RNA, U6 small nuclear 155, pseudogene [Source:HGNC Symbol;Acc:HGNC:47118] | 9106 | 0.000 | -0.0944 | No |
| 19 | AK4P5 | adenylate kinase 4 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:39068] | 9204 | 0.000 | -0.0970 | No |
| 20 | MTHFD2P2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:48860] | 9285 | 0.000 | -0.0992 | No |
| 21 | UBE2V1P15 | ubiquitin conjugating enzyme E2 V1 pseudogene 15 [Source:HGNC Symbol;Acc:HGNC:52414] | 10685 | 0.000 | -0.1370 | No |
| 22 | HMGB1P39 | high mobility group box 1 pseudogene 39 [Source:HGNC Symbol;Acc:HGNC:39186] | 10987 | 0.000 | -0.1451 | No |
| 23 | RNU4-72P | RNA, U4 small nuclear 72, pseudogene [Source:HGNC Symbol;Acc:HGNC:47008] | 11020 | 0.000 | -0.1460 | No |
| 24 | RN7SL643P | RNA, 7SL, cytoplasmic 643, pseudogene [Source:HGNC Symbol;Acc:HGNC:46659] | 11117 | 0.000 | -0.1486 | No |
| 25 | TBX18-AS1 | TBX18 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:52256] | 11924 | 0.000 | -0.1704 | No |
| 26 | RNU6-1338P | RNA, U6 small nuclear 1338, pseudogene [Source:HGNC Symbol;Acc:HGNC:48301] | 12076 | 0.000 | -0.1744 | No |
| 27 | MRAP2 | melanocortin 2 receptor accessory protein 2 [Source:HGNC Symbol;Acc:HGNC:21232] | 13812 | 0.000 | -0.2213 | No |
| 28 | RNU6-261P | RNA, U6 small nuclear 261, pseudogene [Source:HGNC Symbol;Acc:HGNC:47224] | 14233 | 0.000 | -0.2327 | No |
| 29 | DBIP1 | DBI pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:2692] | 14583 | 0.000 | -0.2421 | No |
| 30 | LINC02540 | long intergenic non-protein coding RNA 2540 [Source:HGNC Symbol;Acc:HGNC:53573] | 14633 | 0.000 | -0.2434 | No |
| 31 | LINC02542 | long intergenic non-protein coding RNA 2542 [Source:HGNC Symbol;Acc:HGNC:53576] | 14634 | 0.000 | -0.2434 | No |
| 32 | LINC02535 | long intergenic non-protein coding RNA 2535 [Source:HGNC Symbol;Acc:HGNC:53569] | 14644 | 0.000 | -0.2437 | No |
| 33 | HTR1E | 5-hydroxytryptamine receptor 1E [Source:HGNC Symbol;Acc:HGNC:5291] | 15570 | 0.000 | -0.2687 | No |
| 34 | TBX18 | T-box transcription factor 18 [Source:HGNC Symbol;Acc:HGNC:11595] | 15733 | 0.000 | -0.2730 | No |
| 35 | CGA | glycoprotein hormones, alpha polypeptide [Source:HGNC Symbol;Acc:HGNC:1885] | 15766 | 0.000 | -0.2739 | No |
| 36 | SNORA70 | small nucleolar RNA, H/ACA box 70 [Source:HGNC Symbol;Acc:HGNC:10231] | 16148 | 0.000 | -0.2842 | No |
| 37 | MEI4 | meiotic double-stranded break formation protein 4 [Source:HGNC Symbol;Acc:HGNC:43638] | 16412 | 0.000 | -0.2913 | No |
| 38 | RN7SKP209 | RN7SK pseudogene 209 [Source:HGNC Symbol;Acc:HGNC:45933] | 18236 | 0.000 | -0.3406 | No |
| 39 | SMIM11P1 | small integral membrane protein 11 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:21400] | 18584 | 0.000 | -0.3499 | No |
| 40 | RNU6-248P | RNA, U6 small nuclear 248, pseudogene [Source:HGNC Symbol;Acc:HGNC:47211] | 19368 | 0.000 | -0.3711 | No |
| 41 | SNHG5 | small nucleolar RNA host gene 5 [Source:HGNC Symbol;Acc:HGNC:21026] | 19434 | 0.000 | -0.3729 | No |
| 42 | RNA5SP209 | RNA, 5S ribosomal pseudogene 209 [Source:HGNC Symbol;Acc:HGNC:43109] | 19464 | 0.000 | -0.3736 | No |
| 43 | RNA5SP210 | RNA, 5S ribosomal pseudogene 210 [Source:HGNC Symbol;Acc:HGNC:43110] | 19509 | 0.000 | -0.3748 | No |
| 44 | KRT18P64 | keratin 18 pseudogene 64 [Source:HGNC Symbol;Acc:HGNC:48891] | 20590 | 0.000 | -0.4040 | No |
| 45 | RNU4-12P | RNA, U4 small nuclear 12, pseudogene [Source:HGNC Symbol;Acc:HGNC:46948] | 20848 | 0.000 | -0.4110 | No |
| 46 | HMGN3 | high mobility group nucleosomal binding domain 3 [Source:HGNC Symbol;Acc:HGNC:12312] | 21709 | 0.000 | -0.4342 | No |
| 47 | SNAP91 | synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986] | 21873 | 0.000 | -0.4386 | No |
| 48 | MIR4463 | microRNA 4463 [Source:HGNC Symbol;Acc:HGNC:41665] | 22872 | 0.000 | -0.4656 | No |
| 49 | LAP3P1 | leucine aminopeptidase 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:42364] | 23131 | 0.000 | -0.4725 | No |
| 50 | ELOVL4 | ELOVL fatty acid elongase 4 [Source:HGNC Symbol;Acc:HGNC:14415] | 23142 | 0.000 | -0.4728 | No |
| 51 | RNU1-34P | RNA, U1 small nuclear 34, pseudogene [Source:HGNC Symbol;Acc:HGNC:48376] | 23413 | 0.000 | -0.4801 | No |
| 52 | RIPPLY2 | ripply transcriptional repressor 2 [Source:HGNC Symbol;Acc:HGNC:21390] | 23441 | 0.000 | -0.4808 | No |
| 53 | FILIP1 | filamin A interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:21015] | 23464 | 0.000 | -0.4814 | No |
| 54 | IMPG1 | interphotoreceptor matrix proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:6055] | 23483 | 0.000 | -0.4819 | No |
| 55 | RNU6-1016P | RNA, U6 small nuclear 1016, pseudogene [Source:HGNC Symbol;Acc:HGNC:47979] | 24432 | 0.000 | -0.5075 | No |
| 56 | RN7SKP163 | RN7SK pseudogene 163 [Source:HGNC Symbol;Acc:HGNC:45887] | 25162 | 0.000 | -0.5272 | No |
| 57 | NDUFA5P9 | NADH:ubiquinone oxidoreductase subunit A5 pseudogene 9 [Source:HGNC Symbol;Acc:HGNC:48851] | 26338 | 0.000 | -0.5590 | No |
| 58 | HMGN3-AS1 | HMGN3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48984] | 26898 | 0.000 | -0.5741 | No |
| 59 | RPSAP72 | ribosomal protein SA pseudogene 72 [Source:HGNC Symbol;Acc:HGNC:51925] | 27482 | 0.000 | -0.5898 | No |
| 60 | TPT1P6 | tumor protein, translationally-controlled 1 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:49297] | 28530 | -0.004 | -0.6180 | No |
| 61 | HSPD1P10 | heat shock protein family D (Hsp60) member 1 pseudogene 10 [Source:HGNC Symbol;Acc:HGNC:35131] | 28842 | -0.080 | -0.6247 | No |
| 62 | TMEM30A | transmembrane protein 30A [Source:HGNC Symbol;Acc:HGNC:16667] | 29561 | -0.253 | -0.6386 | No |
| 63 | PHIP | pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673] | 30638 | -0.523 | -0.6562 | Yes |
| 64 | RPL7P29 | ribosomal protein L7 pseudogene 29 [Source:HGNC Symbol;Acc:HGNC:35700] | 30749 | -0.555 | -0.6471 | Yes |
| 65 | DOP1A | DOP1 leucine zipper like protein A [Source:HGNC Symbol;Acc:HGNC:21194] | 30982 | -0.605 | -0.6401 | Yes |
| 66 | PGM3 | phosphoglucomutase 3 [Source:HGNC Symbol;Acc:HGNC:8907] | 31316 | -0.708 | -0.6336 | Yes |
| 67 | CEP162 | centrosomal protein 162 [Source:HGNC Symbol;Acc:HGNC:21107] | 31605 | -0.770 | -0.6246 | Yes |
| 68 | BCKDHB | branched chain keto acid dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:987] | 31937 | -0.892 | -0.6141 | Yes |
| 69 | LCA5 | lebercilin LCA5 [Source:HGNC Symbol;Acc:HGNC:31923] | 33633 | -1.452 | -0.6282 | Yes |
| 70 | PKMP3 | pyruvate kinase M1/2 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:44245] | 34377 | -1.795 | -0.6090 | Yes |
| 71 | IRAK1BP1 | interleukin 1 receptor associated kinase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17368] | 34463 | -1.840 | -0.5712 | Yes |
| 72 | SNX14 | sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:14977] | 34711 | -1.975 | -0.5347 | Yes |
| 73 | UBE3D | ubiquitin protein ligase E3D [Source:HGNC Symbol;Acc:HGNC:21381] | 34717 | -1.981 | -0.4916 | Yes |
| 74 | GAPDHP63 | glyceraldehyde 3 phosphate dehydrogenase pseudogene 63 [Source:HGNC Symbol;Acc:HGNC:4157] | 34789 | -2.042 | -0.4489 | Yes |
| 75 | NT5E | 5'-nucleotidase ecto [Source:HGNC Symbol;Acc:HGNC:8021] | 35161 | -2.294 | -0.4088 | Yes |
| 76 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35185 | -2.308 | -0.3590 | Yes |
| 77 | RCN1P1 | reticulocalbin 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:39205] | 35225 | -2.316 | -0.3095 | Yes |
| 78 | RPL7P27 | ribosomal protein L7 pseudogene 27 [Source:HGNC Symbol;Acc:HGNC:36649] | 35657 | -2.608 | -0.2642 | Yes |
| 79 | MYO6 | myosin VI [Source:HGNC Symbol;Acc:HGNC:7605] | 35765 | -2.692 | -0.2083 | Yes |
| 80 | RWDD2A | RWD domain containing 2A [Source:HGNC Symbol;Acc:HGNC:21385] | 36510 | -3.503 | -0.1519 | Yes |
| 81 | DUTP5 | deoxyuridine triphosphatase pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:39518] | 36516 | -3.519 | -0.0752 | Yes |
| 82 | HTR1B | 5-hydroxytryptamine receptor 1B [Source:HGNC Symbol;Acc:HGNC:5287] | 36871 | -4.151 | 0.0059 | Yes |
