Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | GHANDHI_BYSTANDER_IRRADIATION_UP |
| Enrichment Score (ES) | 0.7933375 |
| Normalized Enrichment Score (NES) | 1.9193556 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0017230235 |
| FWER p-Value | 0.013 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.996 | 0.0443 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 18 | 4.924 | 0.0877 | Yes |
| 3 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 25 | 4.883 | 0.1309 | Yes |
| 4 | DUSP5 | dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071] | 35 | 4.838 | 0.1736 | Yes |
| 5 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 43 | 4.784 | 0.2159 | Yes |
| 6 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 45 | 4.752 | 0.2581 | Yes |
| 7 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 51 | 4.691 | 0.2997 | Yes |
| 8 | SERPINB2 | serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584] | 74 | 4.552 | 0.3395 | Yes |
| 9 | CREB5 | cAMP responsive element binding protein 5 [Source:HGNC Symbol;Acc:HGNC:16844] | 95 | 4.409 | 0.3782 | Yes |
| 10 | SLC39A8 | solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862] | 97 | 4.402 | 0.4172 | Yes |
| 11 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 108 | 4.324 | 0.4554 | Yes |
| 12 | SLC7A11 | solute carrier family 7 member 11 [Source:HGNC Symbol;Acc:HGNC:11059] | 174 | 4.001 | 0.4892 | Yes |
| 13 | OSGIN2 | oxidative stress induced growth inhibitor family member 2 [Source:HGNC Symbol;Acc:HGNC:1355] | 238 | 3.715 | 0.5205 | Yes |
| 14 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 241 | 3.703 | 0.5533 | Yes |
| 15 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 305 | 3.508 | 0.5828 | Yes |
| 16 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 390 | 3.237 | 0.6093 | Yes |
| 17 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 497 | 2.945 | 0.6326 | Yes |
| 18 | SLC39A14 | solute carrier family 39 member 14 [Source:HGNC Symbol;Acc:HGNC:20858] | 565 | 2.796 | 0.6556 | Yes |
| 19 | ZC3H12C | zinc finger CCCH-type containing 12C [Source:HGNC Symbol;Acc:HGNC:29362] | 770 | 2.478 | 0.6721 | Yes |
| 20 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 793 | 2.431 | 0.6931 | Yes |
| 21 | MT1G | metallothionein 1G [Source:HGNC Symbol;Acc:HGNC:7399] | 881 | 2.319 | 0.7114 | Yes |
| 22 | MT1H | metallothionein 1H [Source:HGNC Symbol;Acc:HGNC:7400] | 1302 | 1.876 | 0.7167 | Yes |
| 23 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 1359 | 1.862 | 0.7317 | Yes |
| 24 | MT1E | metallothionein 1E [Source:HGNC Symbol;Acc:HGNC:7397] | 1427 | 1.765 | 0.7456 | Yes |
| 25 | AHR | aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348] | 1630 | 1.608 | 0.7544 | Yes |
| 26 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 2048 | 1.323 | 0.7549 | Yes |
| 27 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 2051 | 1.318 | 0.7665 | Yes |
| 28 | PLEK2 | pleckstrin 2 [Source:HGNC Symbol;Acc:HGNC:19238] | 2091 | 1.298 | 0.7770 | Yes |
| 29 | PPP4R3B | protein phosphatase 4 regulatory subunit 3B [Source:HGNC Symbol;Acc:HGNC:29267] | 2460 | 1.142 | 0.7772 | Yes |
| 30 | TNFSF15 | TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931] | 2706 | 1.047 | 0.7799 | Yes |
| 31 | ZSWIM8 | zinc finger SWIM-type containing 8 [Source:HGNC Symbol;Acc:HGNC:23528] | 2844 | 0.987 | 0.7850 | Yes |
| 32 | MT1B | metallothionein 1B [Source:HGNC Symbol;Acc:HGNC:7394] | 3245 | 0.827 | 0.7815 | Yes |
| 33 | C9orf72 | C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337] | 3274 | 0.813 | 0.7880 | Yes |
| 34 | TUT7 | terminal uridylyl transferase 7 [Source:HGNC Symbol;Acc:HGNC:25817] | 3869 | 0.617 | 0.7774 | Yes |
| 35 | RGS9 | regulator of G protein signaling 9 [Source:HGNC Symbol;Acc:HGNC:10004] | 3935 | 0.596 | 0.7810 | Yes |
| 36 | IRAK3 | interleukin 1 receptor associated kinase 3 [Source:HGNC Symbol;Acc:HGNC:17020] | 3956 | 0.590 | 0.7857 | Yes |
| 37 | SLC16A6 | solute carrier family 16 member 6 [Source:HGNC Symbol;Acc:HGNC:10927] | 3969 | 0.587 | 0.7906 | Yes |
| 38 | ATP6V1C1 | ATPase H+ transporting V1 subunit C1 [Source:HGNC Symbol;Acc:HGNC:856] | 4053 | 0.566 | 0.7933 | Yes |
| 39 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 5162 | 0.240 | 0.7655 | No |
| 40 | NAMPTP1 | nicotinamide phosphoribosyltransferase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:17633] | 6137 | 0.059 | 0.7397 | No |
| 41 | MCTP1 | multiple C2 and transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26183] | 8033 | 0.000 | 0.6885 | No |
| 42 | MCTP2 | multiple C2 and transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25636] | 8047 | 0.000 | 0.6882 | No |
| 43 | POPDC3 | popeye domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17649] | 8822 | 0.000 | 0.6673 | No |
| 44 | SLC16A6P1 | SLC16A6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:48932] | 10494 | 0.000 | 0.6221 | No |
| 45 | B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:15684] | 10828 | 0.000 | 0.6131 | No |
| 46 | SLC6A15 | solute carrier family 6 member 15 [Source:HGNC Symbol;Acc:HGNC:13621] | 11960 | 0.000 | 0.5825 | No |
| 47 | PTGFR | prostaglandin F receptor [Source:HGNC Symbol;Acc:HGNC:9600] | 11976 | 0.000 | 0.5821 | No |
| 48 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 12443 | 0.000 | 0.5695 | No |
| 49 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13881 | 0.000 | 0.5307 | No |
| 50 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:5208] | 14477 | 0.000 | 0.5146 | No |
| 51 | EPB41L4B | erythrocyte membrane protein band 4.1 like 4B [Source:HGNC Symbol;Acc:HGNC:19818] | 15154 | 0.000 | 0.4964 | No |
| 52 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 15804 | 0.000 | 0.4788 | No |
| 53 | PRR7-AS1 | PRR7 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27961] | 17140 | 0.000 | 0.4428 | No |
| 54 | SRSF12 | serine and arginine rich splicing factor 12 [Source:HGNC Symbol;Acc:HGNC:21220] | 17572 | 0.000 | 0.4311 | No |
| 55 | MMP1 | matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155] | 19199 | 0.000 | 0.3872 | No |
| 56 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 19203 | 0.000 | 0.3871 | No |
| 57 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19553 | 0.000 | 0.3777 | No |
| 58 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19562 | 0.000 | 0.3775 | No |
| 59 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19564 | 0.000 | 0.3774 | No |
| 60 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19565 | 0.000 | 0.3774 | No |
| 61 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19567 | 0.000 | 0.3774 | No |
| 62 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 20886 | 0.000 | 0.3418 | No |
| 63 | C2CD4B | C2 calcium dependent domain containing 4B [Source:HGNC Symbol;Acc:HGNC:33628] | 21859 | 0.000 | 0.3155 | No |
| 64 | FGF2 | fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676] | 22749 | 0.000 | 0.2915 | No |
| 65 | TESC | tescalcin [Source:HGNC Symbol;Acc:HGNC:26065] | 25287 | 0.000 | 0.2229 | No |
| 66 | IFNE | interferon epsilon [Source:HGNC Symbol;Acc:HGNC:18163] | 25604 | 0.000 | 0.2144 | No |
| 67 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 25703 | 0.000 | 0.2118 | No |
| 68 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 27090 | 0.000 | 0.1743 | No |
| 69 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 27166 | 0.000 | 0.1723 | No |
| 70 | PHEX | phosphate regulating endopeptidase homolog X-linked [Source:HGNC Symbol;Acc:HGNC:8918] | 27500 | 0.000 | 0.1633 | No |
| 71 | CD69 | CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694] | 28221 | 0.000 | 0.1438 | No |
| 72 | DNAJB4 | DnaJ heat shock protein family (Hsp40) member B4 [Source:HGNC Symbol;Acc:HGNC:14886] | 28708 | -0.050 | 0.1311 | No |
| 73 | RELB | RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] | 29190 | -0.174 | 0.1197 | No |
| 74 | STC1 | stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373] | 29326 | -0.203 | 0.1178 | No |
| 75 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 29743 | -0.301 | 0.1093 | No |
| 76 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 29898 | -0.331 | 0.1081 | No |
| 77 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 30293 | -0.431 | 0.1012 | No |
| 78 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 30579 | -0.507 | 0.0980 | No |
| 79 | PLA2G4A | phospholipase A2 group IVA [Source:HGNC Symbol;Acc:HGNC:9035] | 31436 | -0.744 | 0.0815 | No |
| 80 | GADD45G | growth arrest and DNA damage inducible gamma [Source:HGNC Symbol;Acc:HGNC:4097] | 32339 | -1.023 | 0.0662 | No |
| 81 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 33602 | -1.451 | 0.0450 | No |
| 82 | RNF128 | ring finger protein 128 [Source:HGNC Symbol;Acc:HGNC:21153] | 34252 | -1.744 | 0.0430 | No |
| 83 | LRRC8B | leucine rich repeat containing 8 VRAC subunit B [Source:HGNC Symbol;Acc:HGNC:30692] | 36692 | -3.791 | 0.0108 | No |
