Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | HECKER_IFNB1_TARGETS |
| Enrichment Score (ES) | 0.79957765 |
| Normalized Enrichment Score (NES) | 2.0058813 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 42 | 4.786 | 0.0384 | Yes |
| 2 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 115 | 4.296 | 0.0720 | Yes |
| 3 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 131 | 4.203 | 0.1064 | Yes |
| 4 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 136 | 4.181 | 0.1408 | Yes |
| 5 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 150 | 4.127 | 0.1746 | Yes |
| 6 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 170 | 4.018 | 0.2073 | Yes |
| 7 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 223 | 3.792 | 0.2373 | Yes |
| 8 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 226 | 3.782 | 0.2685 | Yes |
| 9 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 237 | 3.732 | 0.2991 | Yes |
| 10 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 263 | 3.632 | 0.3285 | Yes |
| 11 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 282 | 3.562 | 0.3574 | Yes |
| 12 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 288 | 3.554 | 0.3867 | Yes |
| 13 | STAP1 | signal transducing adaptor family member 1 [Source:HGNC Symbol;Acc:HGNC:24133] | 299 | 3.520 | 0.4155 | Yes |
| 14 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 319 | 3.463 | 0.4437 | Yes |
| 15 | DDX58 | DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102] | 409 | 3.172 | 0.4675 | Yes |
| 16 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 410 | 3.166 | 0.4937 | Yes |
| 17 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 443 | 3.135 | 0.5187 | Yes |
| 18 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 454 | 3.073 | 0.5439 | Yes |
| 19 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 481 | 2.978 | 0.5678 | Yes |
| 20 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 570 | 2.788 | 0.5885 | Yes |
| 21 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 576 | 2.771 | 0.6113 | Yes |
| 22 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 583 | 2.755 | 0.6339 | Yes |
| 23 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 603 | 2.689 | 0.6556 | Yes |
| 24 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 610 | 2.680 | 0.6776 | Yes |
| 25 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 695 | 2.612 | 0.6969 | Yes |
| 26 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 783 | 2.453 | 0.7149 | Yes |
| 27 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 785 | 2.443 | 0.7350 | Yes |
| 28 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 998 | 2.160 | 0.7472 | Yes |
| 29 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 1080 | 2.049 | 0.7619 | Yes |
| 30 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 1162 | 1.942 | 0.7758 | Yes |
| 31 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 1203 | 1.890 | 0.7904 | Yes |
| 32 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 1410 | 1.788 | 0.7996 | Yes |
| 33 | ITGA2B | integrin subunit alpha 2b [Source:HGNC Symbol;Acc:HGNC:6138] | 2043 | 1.328 | 0.7935 | No |
| 34 | SH3BGRL2 | SH3 domain binding glutamate rich protein like 2 [Source:HGNC Symbol;Acc:HGNC:15567] | 2693 | 1.051 | 0.7846 | No |
| 35 | MYL9 | myosin light chain 9 [Source:HGNC Symbol;Acc:HGNC:15754] | 3118 | 0.874 | 0.7804 | No |
| 36 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 4179 | 0.525 | 0.7561 | No |
| 37 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 5009 | 0.285 | 0.7360 | No |
| 38 | DTX3L | deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323] | 5538 | 0.239 | 0.7237 | No |
| 39 | SCO2 | synthesis of cytochrome C oxidase 2 [Source:HGNC Symbol;Acc:HGNC:10604] | 5588 | 0.229 | 0.7243 | No |
| 40 | HES4 | hes family bHLH transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:24149] | 7272 | 0.000 | 0.6788 | No |
| 41 | ARG1 | arginase 1 [Source:HGNC Symbol;Acc:HGNC:663] | 7373 | 0.000 | 0.6761 | No |
| 42 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7817 | 0.000 | 0.6641 | No |
| 43 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 9312 | 0.000 | 0.6238 | No |
| 44 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9342 | 0.000 | 0.6230 | No |
| 45 | FCER1A | Fc fragment of IgE receptor Ia [Source:HGNC Symbol;Acc:HGNC:3609] | 9934 | 0.000 | 0.6070 | No |
| 46 | TYMP | thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148] | 10280 | 0.000 | 0.5977 | No |
| 47 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10584 | 0.000 | 0.5895 | No |
| 48 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12314 | 0.000 | 0.5428 | No |
| 49 | APOBEC3A | apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343] | 12484 | 0.000 | 0.5382 | No |
| 50 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12487 | 0.000 | 0.5381 | No |
| 51 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 13101 | 0.000 | 0.5216 | No |
| 52 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 13490 | 0.000 | 0.5111 | No |
| 53 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 15804 | 0.000 | 0.4486 | No |
| 54 | GP9 | glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444] | 17164 | 0.000 | 0.4118 | No |
| 55 | SERPING1 | serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228] | 17835 | 0.000 | 0.3937 | No |
| 56 | SPON2 | spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253] | 19039 | 0.000 | 0.3612 | No |
| 57 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19553 | 0.000 | 0.3474 | No |
| 58 | HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 [Source:HGNC Symbol;Acc:HGNC:24368] | 19848 | 0.000 | 0.3394 | No |
| 59 | CHI3L1 | chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932] | 19963 | 0.000 | 0.3363 | No |
| 60 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 20379 | 0.000 | 0.3251 | No |
| 61 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 20380 | 0.000 | 0.3251 | No |
| 62 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 20820 | 0.000 | 0.3132 | No |
| 63 | KCNJ15 | potassium inwardly rectifying channel subfamily J member 15 [Source:HGNC Symbol;Acc:HGNC:6261] | 21037 | 0.000 | 0.3074 | No |
| 64 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 21120 | 0.000 | 0.3052 | No |
| 65 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 21708 | 0.000 | 0.2893 | No |
| 66 | CABP5 | calcium binding protein 5 [Source:HGNC Symbol;Acc:HGNC:13714] | 21976 | 0.000 | 0.2821 | No |
| 67 | ZBP1 | Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176] | 23306 | 0.000 | 0.2462 | No |
| 68 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 23433 | 0.000 | 0.2428 | No |
| 69 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 24714 | 0.000 | 0.2082 | No |
| 70 | C1QB | complement C1q B chain [Source:HGNC Symbol;Acc:HGNC:1242] | 24879 | 0.000 | 0.2038 | No |
| 71 | C1QA | complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241] | 24880 | 0.000 | 0.2038 | No |
| 72 | C1QC | complement C1q C chain [Source:HGNC Symbol;Acc:HGNC:1245] | 24898 | 0.000 | 0.2033 | No |
| 73 | FFAR2 | free fatty acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:4501] | 25481 | 0.000 | 0.1876 | No |
| 74 | IFI6 | interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] | 25495 | 0.000 | 0.1872 | No |
| 75 | MMP25 | matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246] | 25691 | 0.000 | 0.1819 | No |
| 76 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 25839 | 0.000 | 0.1780 | No |
| 77 | CMTM5 | CKLF like MARVEL transmembrane domain containing 5 [Source:HGNC Symbol;Acc:HGNC:19176] | 27125 | 0.000 | 0.1432 | No |
| 78 | CMTM2 | CKLF like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19173] | 27138 | 0.000 | 0.1429 | No |
| 79 | TRBV27 | T cell receptor beta variable 27 [Source:HGNC Symbol;Acc:HGNC:12208] | 27777 | 0.000 | 0.1257 | No |
| 80 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 28028 | 0.000 | 0.1189 | No |
| 81 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 28039 | 0.000 | 0.1186 | No |
| 82 | RPS23 | ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:10410] | 29658 | -0.280 | 0.0772 | No |
| 83 | MGAM | maltase-glucoamylase [Source:HGNC Symbol;Acc:HGNC:7043] | 30424 | -0.471 | 0.0605 | No |
| 84 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 30450 | -0.479 | 0.0637 | No |
| 85 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 31053 | -0.630 | 0.0527 | No |
| 86 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 32657 | -1.134 | 0.0187 | No |
| 87 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 33602 | -1.451 | 0.0052 | No |
| 88 | JUP | junction plakoglobin [Source:HGNC Symbol;Acc:HGNC:6207] | 34241 | -1.737 | 0.0023 | No |
| 89 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 34668 | -1.946 | 0.0069 | No |
| 90 | TREML1 | triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434] | 34830 | -2.071 | 0.0197 | No |
| 91 | CYP4F3 | cytochrome P450 family 4 subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:2646] | 35396 | -2.391 | 0.0242 | No |
| 92 | PROS1 | protein S [Source:HGNC Symbol;Acc:HGNC:9456] | 35659 | -2.608 | 0.0387 | No |
