Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | ISHIDA_E2F_TARGETS |
| Enrichment Score (ES) | -0.8657207 |
| Normalized Enrichment Score (NES) | -1.6954106 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0033016158 |
| FWER p-Value | 0.038 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ANXA8L1 | annexin A8 like 1 [Source:HGNC Symbol;Acc:HGNC:23334] | 27174 | 0.000 | -0.7336 | No |
| 2 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 28955 | -0.111 | -0.7806 | No |
| 3 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 30002 | -0.356 | -0.8054 | No |
| 4 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30062 | -0.369 | -0.8035 | No |
| 5 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 30165 | -0.400 | -0.8024 | No |
| 6 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32513 | -1.089 | -0.8552 | Yes |
| 7 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 32901 | -1.221 | -0.8539 | Yes |
| 8 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 32933 | -1.233 | -0.8428 | Yes |
| 9 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 32981 | -1.249 | -0.8320 | Yes |
| 10 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33194 | -1.331 | -0.8249 | Yes |
| 11 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 33198 | -1.332 | -0.8121 | Yes |
| 12 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33400 | -1.422 | -0.8038 | Yes |
| 13 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 33437 | -1.439 | -0.7909 | Yes |
| 14 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 33447 | -1.444 | -0.7772 | Yes |
| 15 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 33637 | -1.452 | -0.7683 | Yes |
| 16 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 33676 | -1.467 | -0.7552 | Yes |
| 17 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33722 | -1.484 | -0.7421 | Yes |
| 18 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 33754 | -1.495 | -0.7285 | Yes |
| 19 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33797 | -1.517 | -0.7150 | Yes |
| 20 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 34210 | -1.718 | -0.7095 | Yes |
| 21 | CDT1 | chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576] | 34351 | -1.787 | -0.6960 | Yes |
| 22 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 34482 | -1.849 | -0.6817 | Yes |
| 23 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 34487 | -1.852 | -0.6640 | Yes |
| 24 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 34602 | -1.924 | -0.6485 | Yes |
| 25 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 34662 | -1.944 | -0.6313 | Yes |
| 26 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 34774 | -2.027 | -0.6147 | Yes |
| 27 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34782 | -2.033 | -0.5953 | Yes |
| 28 | LBR | lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518] | 34935 | -2.136 | -0.5788 | Yes |
| 29 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35007 | -2.177 | -0.5597 | Yes |
| 30 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 35078 | -2.229 | -0.5401 | Yes |
| 31 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 35378 | -2.378 | -0.5252 | Yes |
| 32 | ANLN | anillin actin binding protein [Source:HGNC Symbol;Acc:HGNC:14082] | 35388 | -2.383 | -0.5025 | Yes |
| 33 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 35466 | -2.446 | -0.4809 | Yes |
| 34 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35503 | -2.478 | -0.4580 | Yes |
| 35 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35520 | -2.493 | -0.4344 | Yes |
| 36 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 35566 | -2.530 | -0.4112 | Yes |
| 37 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 35570 | -2.532 | -0.3868 | Yes |
| 38 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35581 | -2.547 | -0.3625 | Yes |
| 39 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 35593 | -2.558 | -0.3381 | Yes |
| 40 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35643 | -2.607 | -0.3143 | Yes |
| 41 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 35671 | -2.612 | -0.2898 | Yes |
| 42 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 35813 | -2.748 | -0.2671 | Yes |
| 43 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 35839 | -2.770 | -0.2411 | Yes |
| 44 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 35850 | -2.788 | -0.2144 | Yes |
| 45 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36290 | -3.231 | -0.1951 | Yes |
| 46 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36293 | -3.235 | -0.1639 | Yes |
| 47 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36496 | -3.483 | -0.1358 | Yes |
| 48 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36523 | -3.525 | -0.1025 | Yes |
| 49 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 36662 | -3.744 | -0.0701 | Yes |
| 50 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36799 | -4.008 | -0.0351 | Yes |
| 51 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 36977 | -4.446 | 0.0031 | Yes |
