Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | KONG_E2F3_TARGETS |
| Enrichment Score (ES) | -0.7817194 |
| Normalized Enrichment Score (NES) | -1.6312633 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.018044736 |
| FWER p-Value | 0.347 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAS5 | growth arrest specific 5 [Source:HGNC Symbol;Acc:HGNC:16355] | 194 | 3.903 | 0.0182 | No |
| 2 | NR1D1 | nuclear receptor subfamily 1 group D member 1 [Source:HGNC Symbol;Acc:HGNC:7962] | 582 | 2.758 | 0.0243 | No |
| 3 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 2773 | 1.019 | -0.0288 | No |
| 4 | SRSF7 | serine and arginine rich splicing factor 7 [Source:HGNC Symbol;Acc:HGNC:10789] | 3218 | 0.837 | -0.0358 | No |
| 5 | FBXO45 | F-box protein 45 [Source:HGNC Symbol;Acc:HGNC:29148] | 3932 | 0.596 | -0.0515 | No |
| 6 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 3986 | 0.583 | -0.0494 | No |
| 7 | H4C15 | H4 clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:29607] | 12673 | 0.000 | -0.2842 | No |
| 8 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16745 | 0.000 | -0.3943 | No |
| 9 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 17023 | 0.000 | -0.4017 | No |
| 10 | MYB | MYB proto-oncogene, transcription factor [Source:HGNC Symbol;Acc:HGNC:7545] | 19271 | 0.000 | -0.4625 | No |
| 11 | TAL2 | TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557] | 19322 | 0.000 | -0.4638 | No |
| 12 | GP1BA | glycoprotein Ib platelet subunit alpha [Source:HGNC Symbol;Acc:HGNC:4439] | 20427 | 0.000 | -0.4937 | No |
| 13 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 21286 | 0.000 | -0.5169 | No |
| 14 | IGF2BP1 | insulin like growth factor 2 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:28866] | 21372 | 0.000 | -0.5192 | No |
| 15 | PRL | prolactin [Source:HGNC Symbol;Acc:HGNC:9445] | 24867 | 0.000 | -0.6136 | No |
| 16 | PSORS1C2 | psoriasis susceptibility 1 candidate 2 [Source:HGNC Symbol;Acc:HGNC:17199] | 25559 | 0.000 | -0.6323 | No |
| 17 | F13A1 | coagulation factor XIII A chain [Source:HGNC Symbol;Acc:HGNC:3531] | 27923 | 0.000 | -0.6962 | No |
| 18 | FAM111A | family with sequence similarity 111 member A [Source:HGNC Symbol;Acc:HGNC:24725] | 28698 | -0.046 | -0.7168 | No |
| 19 | MAPK8 | mitogen-activated protein kinase 8 [Source:HGNC Symbol;Acc:HGNC:6881] | 29333 | -0.205 | -0.7327 | No |
| 20 | RBBP8 | RB binding protein 8, endonuclease [Source:HGNC Symbol;Acc:HGNC:9891] | 30551 | -0.498 | -0.7626 | No |
| 21 | CENPQ | centromere protein Q [Source:HGNC Symbol;Acc:HGNC:21347] | 30958 | -0.599 | -0.7700 | No |
| 22 | RPL12 | ribosomal protein L12 [Source:HGNC Symbol;Acc:HGNC:10302] | 31019 | -0.619 | -0.7679 | No |
| 23 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 31105 | -0.646 | -0.7663 | No |
| 24 | DEPDC1 | DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949] | 31388 | -0.729 | -0.7696 | No |
| 25 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 31405 | -0.734 | -0.7656 | No |
| 26 | RPRD1B | regulation of nuclear pre-mRNA domain containing 1B [Source:HGNC Symbol;Acc:HGNC:16209] | 31408 | -0.735 | -0.7612 | No |
| 27 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32001 | -0.913 | -0.7718 | No |
| 28 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 32370 | -1.033 | -0.7755 | Yes |
| 29 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 32391 | -1.038 | -0.7698 | Yes |
| 30 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32513 | -1.089 | -0.7666 | Yes |
| 31 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 32541 | -1.098 | -0.7607 | Yes |
| 32 | USP1 | ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607] | 32614 | -1.123 | -0.7559 | Yes |
| 33 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 32716 | -1.154 | -0.7517 | Yes |
| 34 | NUP50 | nucleoporin 50 [Source:HGNC Symbol;Acc:HGNC:8065] | 32866 | -1.206 | -0.7485 | Yes |
| 35 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 32901 | -1.221 | -0.7421 | Yes |
| 36 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 33083 | -1.285 | -0.7393 | Yes |
| 37 | TAF1D | TATA-box binding protein associated factor, RNA polymerase I subunit D [Source:HGNC Symbol;Acc:HGNC:28759] | 33164 | -1.318 | -0.7335 | Yes |
| 38 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33194 | -1.331 | -0.7263 | Yes |
| 39 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 33207 | -1.335 | -0.7186 | Yes |
| 40 | FIGNL1 | fidgetin like 1 [Source:HGNC Symbol;Acc:HGNC:13286] | 33212 | -1.337 | -0.7107 | Yes |
| 41 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 33285 | -1.369 | -0.7044 | Yes |
| 42 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33400 | -1.422 | -0.6990 | Yes |
| 43 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 33437 | -1.439 | -0.6913 | Yes |
| 44 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 33447 | -1.444 | -0.6829 | Yes |
| 45 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33722 | -1.484 | -0.6814 | Yes |
| 46 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 33799 | -1.519 | -0.6743 | Yes |
| 47 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 33895 | -1.555 | -0.6676 | Yes |
| 48 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 33966 | -1.594 | -0.6599 | Yes |
| 49 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 34102 | -1.666 | -0.6536 | Yes |
| 50 | RPL3 | ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10332] | 34170 | -1.698 | -0.6452 | Yes |
| 51 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 34210 | -1.718 | -0.6359 | Yes |
| 52 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34312 | -1.770 | -0.6280 | Yes |
| 53 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 34487 | -1.852 | -0.6216 | Yes |
| 54 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34488 | -1.854 | -0.6105 | Yes |
| 55 | RBL1 | RB transcriptional corepressor like 1 [Source:HGNC Symbol;Acc:HGNC:9893] | 34506 | -1.861 | -0.5998 | Yes |
| 56 | ERCC6L | ERCC excision repair 6 like, spindle assembly checkpoint helicase [Source:HGNC Symbol;Acc:HGNC:20794] | 34544 | -1.892 | -0.5894 | Yes |
| 57 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 34591 | -1.917 | -0.5792 | Yes |
| 58 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 34602 | -1.924 | -0.5679 | Yes |
| 59 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 34662 | -1.944 | -0.5578 | Yes |
| 60 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 34669 | -1.947 | -0.5463 | Yes |
| 61 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34681 | -1.952 | -0.5349 | Yes |
| 62 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 34689 | -1.957 | -0.5233 | Yes |
| 63 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34782 | -2.033 | -0.5136 | Yes |
| 64 | PSIP1 | PC4 and SFRS1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9527] | 34931 | -2.131 | -0.5048 | Yes |
| 65 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 34966 | -2.148 | -0.4928 | Yes |
| 66 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35007 | -2.177 | -0.4809 | Yes |
| 67 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 35078 | -2.229 | -0.4694 | Yes |
| 68 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 35121 | -2.265 | -0.4569 | Yes |
| 69 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 35141 | -2.278 | -0.4437 | Yes |
| 70 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35306 | -2.318 | -0.4343 | Yes |
| 71 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 35360 | -2.355 | -0.4216 | Yes |
| 72 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 35363 | -2.359 | -0.4075 | Yes |
| 73 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 35378 | -2.378 | -0.3936 | Yes |
| 74 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 35444 | -2.426 | -0.3808 | Yes |
| 75 | NCAPG2 | non-SMC condensin II complex subunit G2 [Source:HGNC Symbol;Acc:HGNC:21904] | 35448 | -2.435 | -0.3662 | Yes |
| 76 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35503 | -2.478 | -0.3528 | Yes |
| 77 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35520 | -2.493 | -0.3383 | Yes |
| 78 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 35570 | -2.532 | -0.3244 | Yes |
| 79 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35576 | -2.541 | -0.3093 | Yes |
| 80 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 35611 | -2.573 | -0.2948 | Yes |
| 81 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35643 | -2.607 | -0.2800 | Yes |
| 82 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 35725 | -2.658 | -0.2662 | Yes |
| 83 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 35814 | -2.749 | -0.2521 | Yes |
| 84 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 35850 | -2.788 | -0.2363 | Yes |
| 85 | HLX | H2.0 like homeobox [Source:HGNC Symbol;Acc:HGNC:4978] | 35960 | -2.880 | -0.2220 | Yes |
| 86 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 35994 | -2.919 | -0.2053 | Yes |
| 87 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36026 | -2.958 | -0.1884 | Yes |
| 88 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36053 | -2.978 | -0.1712 | Yes |
| 89 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 36126 | -3.073 | -0.1547 | Yes |
| 90 | BRCA1 | BRCA1 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1100] | 36149 | -3.098 | -0.1368 | Yes |
| 91 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36279 | -3.215 | -0.1209 | Yes |
| 92 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36435 | -3.432 | -0.1045 | Yes |
| 93 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36693 | -3.791 | -0.0887 | Yes |
| 94 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36799 | -4.008 | -0.0675 | Yes |
| 95 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 36809 | -4.009 | -0.0437 | Yes |
| 96 | CBX2 | chromobox 2 [Source:HGNC Symbol;Acc:HGNC:1552] | 36843 | -4.091 | -0.0200 | Yes |
| 97 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 36977 | -4.446 | 0.0031 | Yes |
