Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | LEE_EARLY_T_LYMPHOCYTE_UP |
| Enrichment Score (ES) | -0.7775256 |
| Normalized Enrichment Score (NES) | -1.6592484 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.008634233 |
| FWER p-Value | 0.137 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RAPGEF5 | Rap guanine nucleotide exchange factor 5 [Source:HGNC Symbol;Acc:HGNC:16862] | 348 | 3.365 | 0.0105 | No |
| 2 | SYK | spleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491] | 1131 | 1.973 | 0.0010 | No |
| 3 | PON1 | paraoxonase 1 [Source:HGNC Symbol;Acc:HGNC:9204] | 1568 | 1.655 | -0.0010 | No |
| 4 | SLC1A4 | solute carrier family 1 member 4 [Source:HGNC Symbol;Acc:HGNC:10942] | 1912 | 1.409 | -0.0019 | No |
| 5 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2837 | 0.990 | -0.0210 | No |
| 6 | CENPW | centromere protein W [Source:HGNC Symbol;Acc:HGNC:21488] | 2936 | 0.947 | -0.0181 | No |
| 7 | CDC25A | cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725] | 3493 | 0.738 | -0.0287 | No |
| 8 | AEBP1 | AE binding protein 1 [Source:HGNC Symbol;Acc:HGNC:303] | 4591 | 0.409 | -0.0560 | No |
| 9 | GSE1 | Gse1 coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:28979] | 5639 | 0.211 | -0.0830 | No |
| 10 | GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4129] | 5707 | 0.188 | -0.0837 | No |
| 11 | FAIM | Fas apoptotic inhibitory molecule [Source:HGNC Symbol;Acc:HGNC:18703] | 5709 | 0.188 | -0.0827 | No |
| 12 | MIR646HG | MIR646 host gene [Source:HGNC Symbol;Acc:HGNC:27659] | 8134 | 0.000 | -0.1482 | No |
| 13 | HHIP | hedgehog interacting protein [Source:HGNC Symbol;Acc:HGNC:14866] | 8213 | 0.000 | -0.1503 | No |
| 14 | TNFRSF21 | TNF receptor superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:13469] | 9386 | 0.000 | -0.1820 | No |
| 15 | CRNDE | colorectal neoplasia differentially expressed [Source:HGNC Symbol;Acc:HGNC:37078] | 11542 | 0.000 | -0.2403 | No |
| 16 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12535 | 0.000 | -0.2671 | No |
| 17 | SCRN1 | secernin 1 [Source:HGNC Symbol;Acc:HGNC:22192] | 14158 | 0.000 | -0.3109 | No |
| 18 | MZB1 | marginal zone B and B1 cell specific protein [Source:HGNC Symbol;Acc:HGNC:30125] | 14781 | 0.000 | -0.3278 | No |
| 19 | PALLD | palladin, cytoskeletal associated protein [Source:HGNC Symbol;Acc:HGNC:17068] | 16710 | 0.000 | -0.3799 | No |
| 20 | PALM2AKAP2 | PALM2 and AKAP2 fusion [Source:HGNC Symbol;Acc:HGNC:33529] | 18002 | 0.000 | -0.4148 | No |
| 21 | MYB | MYB proto-oncogene, transcription factor [Source:HGNC Symbol;Acc:HGNC:7545] | 19271 | 0.000 | -0.4491 | No |
| 22 | CPVL | carboxypeptidase vitellogenic like [Source:HGNC Symbol;Acc:HGNC:14399] | 20891 | 0.000 | -0.4929 | No |
| 23 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 21259 | 0.000 | -0.5028 | No |
| 24 | NLGN4X | neuroligin 4 X-linked [Source:HGNC Symbol;Acc:HGNC:14287] | 22843 | 0.000 | -0.5456 | No |
| 25 | ARPP21 | cAMP regulated phosphoprotein 21 [Source:HGNC Symbol;Acc:HGNC:16968] | 25909 | 0.000 | -0.6285 | No |
| 26 | TSHR | thyroid stimulating hormone receptor [Source:HGNC Symbol;Acc:HGNC:12373] | 27129 | 0.000 | -0.6614 | No |
| 27 | FAM72C | family with sequence similarity 72 member C [Source:HGNC Symbol;Acc:HGNC:30602] | 27429 | 0.000 | -0.6695 | No |
| 28 | CD1E | CD1e molecule [Source:HGNC Symbol;Acc:HGNC:1638] | 28092 | 0.000 | -0.6874 | No |
| 29 | CD1B | CD1b molecule [Source:HGNC Symbol;Acc:HGNC:1635] | 28095 | 0.000 | -0.6875 | No |
| 30 | CD1A | CD1a molecule [Source:HGNC Symbol;Acc:HGNC:1634] | 28096 | 0.000 | -0.6875 | No |
| 31 | CD99 | CD99 molecule (Xg blood group) [Source:HGNC Symbol;Acc:HGNC:7082] | 28250 | 0.000 | -0.6916 | No |
| 32 | GGH | gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] | 28872 | -0.092 | -0.7079 | No |
| 33 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 28955 | -0.111 | -0.7094 | No |
| 34 | GNA15 | G protein subunit alpha 15 [Source:HGNC Symbol;Acc:HGNC:4383] | 29843 | -0.318 | -0.7315 | No |
| 35 | LETM1 | leucine zipper and EF-hand containing transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:6556] | 29867 | -0.323 | -0.7302 | No |
| 36 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 30002 | -0.356 | -0.7317 | No |
| 37 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 31183 | -0.669 | -0.7597 | No |
| 38 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31219 | -0.678 | -0.7566 | No |
| 39 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 31422 | -0.738 | -0.7577 | No |
| 40 | GFI1 | growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237] | 31667 | -0.790 | -0.7596 | No |
| 41 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32001 | -0.913 | -0.7632 | No |
| 42 | CENPU | centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348] | 32530 | -1.094 | -0.7711 | Yes |
| 43 | RUFY3 | RUN and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30285] | 32652 | -1.133 | -0.7676 | Yes |
| 44 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 32716 | -1.154 | -0.7625 | Yes |
| 45 | TMSB15A | thymosin beta 15a [Source:HGNC Symbol;Acc:HGNC:30744] | 32914 | -1.227 | -0.7606 | Yes |
| 46 | KNL1 | kinetochore scaffold 1 [Source:HGNC Symbol;Acc:HGNC:24054] | 32938 | -1.234 | -0.7539 | Yes |
| 47 | RCAN1 | regulator of calcineurin 1 [Source:HGNC Symbol;Acc:HGNC:3040] | 33051 | -1.276 | -0.7493 | Yes |
| 48 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 33083 | -1.285 | -0.7426 | Yes |
| 49 | DNTT | DNA nucleotidylexotransferase [Source:HGNC Symbol;Acc:HGNC:2983] | 33154 | -1.312 | -0.7367 | Yes |
| 50 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33194 | -1.331 | -0.7299 | Yes |
| 51 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 33203 | -1.334 | -0.7222 | Yes |
| 52 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 33326 | -1.384 | -0.7173 | Yes |
| 53 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 33402 | -1.423 | -0.7109 | Yes |
| 54 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 33442 | -1.442 | -0.7034 | Yes |
| 55 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 33676 | -1.467 | -0.7011 | Yes |
| 56 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 33966 | -1.594 | -0.6994 | Yes |
| 57 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 33991 | -1.612 | -0.6906 | Yes |
| 58 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 34182 | -1.707 | -0.6856 | Yes |
| 59 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 34210 | -1.718 | -0.6761 | Yes |
| 60 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34312 | -1.770 | -0.6684 | Yes |
| 61 | MPP1 | membrane palmitoylated protein 1 [Source:HGNC Symbol;Acc:HGNC:7219] | 34321 | -1.778 | -0.6581 | Yes |
| 62 | DIAPH3 | diaphanous related formin 3 [Source:HGNC Symbol;Acc:HGNC:15480] | 34428 | -1.819 | -0.6502 | Yes |
| 63 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 34445 | -1.828 | -0.6398 | Yes |
| 64 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34488 | -1.854 | -0.6300 | Yes |
| 65 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 34533 | -1.882 | -0.6200 | Yes |
| 66 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 34591 | -1.917 | -0.6102 | Yes |
| 67 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 34662 | -1.944 | -0.6006 | Yes |
| 68 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 34669 | -1.947 | -0.5893 | Yes |
| 69 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 34689 | -1.957 | -0.5782 | Yes |
| 70 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 34739 | -1.998 | -0.5677 | Yes |
| 71 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34782 | -2.033 | -0.5568 | Yes |
| 72 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 34879 | -2.099 | -0.5470 | Yes |
| 73 | CEP128 | centrosomal protein 128 [Source:HGNC Symbol;Acc:HGNC:20359] | 34962 | -2.147 | -0.5365 | Yes |
| 74 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 34966 | -2.148 | -0.5238 | Yes |
| 75 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 35002 | -2.171 | -0.5119 | Yes |
| 76 | ATAD2 | ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123] | 35076 | -2.228 | -0.5007 | Yes |
| 77 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 35078 | -2.229 | -0.4876 | Yes |
| 78 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 35090 | -2.241 | -0.4746 | Yes |
| 79 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35185 | -2.308 | -0.4635 | Yes |
| 80 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35306 | -2.318 | -0.4530 | Yes |
| 81 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 35444 | -2.426 | -0.4423 | Yes |
| 82 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35503 | -2.478 | -0.4293 | Yes |
| 83 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35567 | -2.531 | -0.4160 | Yes |
| 84 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 35570 | -2.532 | -0.4010 | Yes |
| 85 | CXXC5 | CXXC finger protein 5 [Source:HGNC Symbol;Acc:HGNC:26943] | 35572 | -2.539 | -0.3860 | Yes |
| 86 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35576 | -2.541 | -0.3711 | Yes |
| 87 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35581 | -2.547 | -0.3561 | Yes |
| 88 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 35593 | -2.558 | -0.3413 | Yes |
| 89 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 35611 | -2.573 | -0.3265 | Yes |
| 90 | LRR1 | leucine rich repeat protein 1 [Source:HGNC Symbol;Acc:HGNC:19742] | 35641 | -2.601 | -0.3119 | Yes |
| 91 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35643 | -2.607 | -0.2965 | Yes |
| 92 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 35708 | -2.647 | -0.2826 | Yes |
| 93 | CDCA2 | cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623] | 35809 | -2.746 | -0.2690 | Yes |
| 94 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 35837 | -2.768 | -0.2534 | Yes |
| 95 | CEP55 | centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161] | 35865 | -2.794 | -0.2376 | Yes |
| 96 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 35873 | -2.813 | -0.2211 | Yes |
| 97 | KIF15 | kinesin family member 15 [Source:HGNC Symbol;Acc:HGNC:17273] | 35946 | -2.862 | -0.2061 | Yes |
| 98 | LDLRAD4 | low density lipoprotein receptor class A domain containing 4 [Source:HGNC Symbol;Acc:HGNC:1224] | 36016 | -2.943 | -0.1905 | Yes |
| 99 | UHRF1 | ubiquitin like with PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:12556] | 36104 | -3.045 | -0.1749 | Yes |
| 100 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36198 | -3.169 | -0.1586 | Yes |
| 101 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36290 | -3.231 | -0.1420 | Yes |
| 102 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36367 | -3.347 | -0.1242 | Yes |
| 103 | E2F2 | E2F transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:3114] | 36398 | -3.383 | -0.1050 | Yes |
| 104 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36693 | -3.791 | -0.0905 | Yes |
| 105 | NEIL3 | nei like DNA glycosylase 3 [Source:HGNC Symbol;Acc:HGNC:24573] | 36775 | -3.954 | -0.0693 | Yes |
| 106 | TFDP2 | transcription factor Dp-2 [Source:HGNC Symbol;Acc:HGNC:11751] | 36888 | -4.209 | -0.0474 | Yes |
| 107 | E2F7 | E2F transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:23820] | 36907 | -4.260 | -0.0227 | Yes |
| 108 | DSCC1 | DNA replication and sister chromatid cohesion 1 [Source:HGNC Symbol;Acc:HGNC:24453] | 37029 | -4.668 | 0.0016 | Yes |
