Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | LINDSTEDT_DENDRITIC_CELL_MATURATION_A |
| Enrichment Score (ES) | 0.8201709 |
| Normalized Enrichment Score (NES) | 1.9179938 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0016978269 |
| FWER p-Value | 0.014 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.996 | 0.0588 | Yes |
| 2 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 8 | 4.983 | 0.1174 | Yes |
| 3 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 12 | 4.975 | 0.1759 | Yes |
| 4 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 20 | 4.911 | 0.2336 | Yes |
| 5 | HCAR3 | hydroxycarboxylic acid receptor 3 [Source:HGNC Symbol;Acc:HGNC:16824] | 36 | 4.837 | 0.2902 | Yes |
| 6 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 56 | 4.661 | 0.3446 | Yes |
| 7 | EDN1 | endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176] | 127 | 4.234 | 0.3925 | Yes |
| 8 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 128 | 4.232 | 0.4424 | Yes |
| 9 | SLC7A11 | solute carrier family 7 member 11 [Source:HGNC Symbol;Acc:HGNC:11059] | 174 | 4.001 | 0.4883 | Yes |
| 10 | TFEC | transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754] | 312 | 3.488 | 0.5257 | Yes |
| 11 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 497 | 2.945 | 0.5554 | Yes |
| 12 | MALT1 | MALT1 paracaspase [Source:HGNC Symbol;Acc:HGNC:6819] | 531 | 2.863 | 0.5883 | Yes |
| 13 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 537 | 2.855 | 0.6218 | Yes |
| 14 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 576 | 2.771 | 0.6534 | Yes |
| 15 | PLEK | pleckstrin [Source:HGNC Symbol;Acc:HGNC:9070] | 604 | 2.688 | 0.6843 | Yes |
| 16 | TRIM16 | tripartite motif containing 16 [Source:HGNC Symbol;Acc:HGNC:17241] | 829 | 2.368 | 0.7062 | Yes |
| 17 | CREM | cAMP responsive element modulator [Source:HGNC Symbol;Acc:HGNC:2352] | 840 | 2.352 | 0.7336 | Yes |
| 18 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 995 | 2.163 | 0.7550 | Yes |
| 19 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 998 | 2.160 | 0.7804 | Yes |
| 20 | SLC3A2 | solute carrier family 3 member 2 [Source:HGNC Symbol;Acc:HGNC:11026] | 1619 | 1.616 | 0.7827 | Yes |
| 21 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1942 | 1.389 | 0.7903 | Yes |
| 22 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 2048 | 1.323 | 0.8031 | Yes |
| 23 | PSMA3 | proteasome 20S subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:9532] | 2363 | 1.188 | 0.8086 | Yes |
| 24 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 2674 | 1.056 | 0.8127 | Yes |
| 25 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 2830 | 0.993 | 0.8202 | Yes |
| 26 | GPR137B | G protein-coupled receptor 137B [Source:HGNC Symbol;Acc:HGNC:11862] | 4015 | 0.574 | 0.7950 | No |
| 27 | RAB5A | RAB5A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9783] | 4228 | 0.510 | 0.7952 | No |
| 28 | ACVR2A | activin A receptor type 2A [Source:HGNC Symbol;Acc:HGNC:173] | 4548 | 0.418 | 0.7915 | No |
| 29 | FKBP5 | FKBP prolyl isomerase 5 [Source:HGNC Symbol;Acc:HGNC:3721] | 4991 | 0.291 | 0.7830 | No |
| 30 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 5009 | 0.285 | 0.7859 | No |
| 31 | P2RX4 | purinergic receptor P2X 4 [Source:HGNC Symbol;Acc:HGNC:8535] | 5093 | 0.260 | 0.7868 | No |
| 32 | PTGER4 | prostaglandin E receptor 4 [Source:HGNC Symbol;Acc:HGNC:9596] | 5132 | 0.248 | 0.7887 | No |
| 33 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6427 | 0.000 | 0.7537 | No |
| 34 | STAT4 | signal transducer and activator of transcription 4 [Source:HGNC Symbol;Acc:HGNC:11365] | 7399 | 0.000 | 0.7275 | No |
| 35 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8970 | 0.000 | 0.6851 | No |
| 36 | TNFRSF4 | TNF receptor superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:11918] | 9799 | 0.000 | 0.6627 | No |
| 37 | PLAT | plasminogen activator, tissue type [Source:HGNC Symbol;Acc:HGNC:9051] | 9965 | 0.000 | 0.6583 | No |
| 38 | RTN1 | reticulon 1 [Source:HGNC Symbol;Acc:HGNC:10467] | 10565 | 0.000 | 0.6421 | No |
| 39 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 13957 | 0.000 | 0.5505 | No |
| 40 | NFE2L3 | nuclear factor, erythroid 2 like 3 [Source:HGNC Symbol;Acc:HGNC:7783] | 17619 | 0.000 | 0.4517 | No |
| 41 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 17775 | 0.000 | 0.4475 | No |
| 42 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18323 | 0.000 | 0.4327 | No |
| 43 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 19000 | 0.000 | 0.4144 | No |
| 44 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19553 | 0.000 | 0.3995 | No |
| 45 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19562 | 0.000 | 0.3993 | No |
| 46 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19565 | 0.000 | 0.3993 | No |
| 47 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 21697 | 0.000 | 0.3417 | No |
| 48 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 27090 | 0.000 | 0.1961 | No |
| 49 | PLA2G7 | phospholipase A2 group VII [Source:HGNC Symbol;Acc:HGNC:9040] | 27160 | 0.000 | 0.1942 | No |
| 50 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 28028 | 0.000 | 0.1708 | No |
| 51 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 28037 | 0.000 | 0.1706 | No |
| 52 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 28039 | 0.000 | 0.1706 | No |
| 53 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 28040 | 0.000 | 0.1706 | No |
| 54 | CD48 | CD48 molecule [Source:HGNC Symbol;Acc:HGNC:1683] | 28163 | 0.000 | 0.1673 | No |
| 55 | CD58 | CD58 molecule [Source:HGNC Symbol;Acc:HGNC:1688] | 28198 | 0.000 | 0.1664 | No |
| 56 | ATP13A3 | ATPase 13A3 [Source:HGNC Symbol;Acc:HGNC:24113] | 29371 | -0.215 | 0.1373 | No |
| 57 | PLA2G4A | phospholipase A2 group IVA [Source:HGNC Symbol;Acc:HGNC:9035] | 31436 | -0.744 | 0.0903 | No |
| 58 | SCARF1 | scavenger receptor class F member 1 [Source:HGNC Symbol;Acc:HGNC:16820] | 31478 | -0.757 | 0.0981 | No |
| 59 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 31535 | -0.768 | 0.1056 | No |
| 60 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 33602 | -1.451 | 0.0669 | No |
| 61 | ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3363] | 35193 | -2.311 | 0.0512 | No |
