Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | MORI_IMMATURE_B_LYMPHOCYTE_DN |
| Enrichment Score (ES) | -0.7874444 |
| Normalized Enrichment Score (NES) | -1.6619577 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.009090032 |
| FWER p-Value | 0.125 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 1774 | 1.506 | -0.0378 | No |
| 2 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1858 | 1.456 | -0.0303 | No |
| 3 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 3171 | 0.854 | -0.0600 | No |
| 4 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 3308 | 0.797 | -0.0584 | No |
| 5 | PREP | prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358] | 4175 | 0.526 | -0.0782 | No |
| 6 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] | 4197 | 0.518 | -0.0753 | No |
| 7 | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [Source:HGNC Symbol;Acc:HGNC:11101] | 5079 | 0.263 | -0.0974 | No |
| 8 | CBX1 | chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551] | 6044 | 0.085 | -0.1228 | No |
| 9 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12535 | 0.000 | -0.2983 | No |
| 10 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16745 | 0.000 | -0.4120 | No |
| 11 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18511 | 0.000 | -0.4597 | No |
| 12 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 21259 | 0.000 | -0.5340 | No |
| 13 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 24542 | 0.000 | -0.6227 | No |
| 14 | RAMP1 | receptor activity modifying protein 1 [Source:HGNC Symbol;Acc:HGNC:9843] | 25110 | 0.000 | -0.6380 | No |
| 15 | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100] | 28840 | -0.080 | -0.7382 | No |
| 16 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 28955 | -0.111 | -0.7406 | No |
| 17 | HAUS3 | HAUS augmin like complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28719] | 28979 | -0.116 | -0.7404 | No |
| 18 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 29197 | -0.176 | -0.7451 | No |
| 19 | UCK2 | uridine-cytidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12562] | 29885 | -0.329 | -0.7615 | No |
| 20 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30062 | -0.369 | -0.7637 | No |
| 21 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 30165 | -0.400 | -0.7638 | No |
| 22 | SLC16A1 | solute carrier family 16 member 1 [Source:HGNC Symbol;Acc:HGNC:10922] | 30395 | -0.461 | -0.7669 | No |
| 23 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 31156 | -0.662 | -0.7830 | Yes |
| 24 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31219 | -0.678 | -0.7801 | Yes |
| 25 | ACTN4 | actinin alpha 4 [Source:HGNC Symbol;Acc:HGNC:166] | 31338 | -0.714 | -0.7785 | Yes |
| 26 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 31405 | -0.734 | -0.7754 | Yes |
| 27 | CENPL | centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879] | 31491 | -0.761 | -0.7726 | Yes |
| 28 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 31851 | -0.856 | -0.7765 | Yes |
| 29 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31861 | -0.859 | -0.7710 | Yes |
| 30 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 32121 | -0.949 | -0.7716 | Yes |
| 31 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 32391 | -1.038 | -0.7719 | Yes |
| 32 | HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:HGNC:24941] | 32485 | -1.076 | -0.7672 | Yes |
| 33 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 32505 | -1.086 | -0.7604 | Yes |
| 34 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 32582 | -1.110 | -0.7550 | Yes |
| 35 | RBBP4 | RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887] | 32665 | -1.137 | -0.7496 | Yes |
| 36 | CKAP5 | cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:HGNC:28959] | 32858 | -1.204 | -0.7467 | Yes |
| 37 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 32901 | -1.221 | -0.7397 | Yes |
| 38 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33194 | -1.331 | -0.7386 | Yes |
| 39 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 33207 | -1.335 | -0.7300 | Yes |
| 40 | TUBA1B | tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809] | 33225 | -1.346 | -0.7214 | Yes |
| 41 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33400 | -1.422 | -0.7166 | Yes |
| 42 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 33447 | -1.444 | -0.7081 | Yes |
| 43 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 33676 | -1.467 | -0.7044 | Yes |
| 44 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33722 | -1.484 | -0.6957 | Yes |
| 45 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 33754 | -1.495 | -0.6865 | Yes |
| 46 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 33781 | -1.511 | -0.6770 | Yes |
| 47 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33797 | -1.517 | -0.6673 | Yes |
| 48 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 33991 | -1.612 | -0.6616 | Yes |
| 49 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 34261 | -1.747 | -0.6572 | Yes |
| 50 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34312 | -1.770 | -0.6467 | Yes |
| 51 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 34445 | -1.828 | -0.6380 | Yes |
| 52 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 34487 | -1.852 | -0.6266 | Yes |
| 53 | XRCC6 | X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055] | 34511 | -1.868 | -0.6147 | Yes |
| 54 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 34602 | -1.924 | -0.6042 | Yes |
| 55 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 34662 | -1.944 | -0.5928 | Yes |
| 56 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 34774 | -2.027 | -0.5822 | Yes |
| 57 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34782 | -2.033 | -0.5687 | Yes |
| 58 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 34879 | -2.099 | -0.5572 | Yes |
| 59 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 35078 | -2.229 | -0.5476 | Yes |
| 60 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 35090 | -2.241 | -0.5328 | Yes |
| 61 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 35141 | -2.278 | -0.5189 | Yes |
| 62 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35185 | -2.308 | -0.5046 | Yes |
| 63 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 35205 | -2.315 | -0.4895 | Yes |
| 64 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 35301 | -2.317 | -0.4766 | Yes |
| 65 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 35363 | -2.359 | -0.4624 | Yes |
| 66 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 35378 | -2.378 | -0.4468 | Yes |
| 67 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 35444 | -2.426 | -0.4323 | Yes |
| 68 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35520 | -2.493 | -0.4175 | Yes |
| 69 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35541 | -2.516 | -0.4012 | Yes |
| 70 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35567 | -2.531 | -0.3849 | Yes |
| 71 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35576 | -2.541 | -0.3680 | Yes |
| 72 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35581 | -2.547 | -0.3510 | Yes |
| 73 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 35593 | -2.558 | -0.3342 | Yes |
| 74 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 35611 | -2.573 | -0.3174 | Yes |
| 75 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35643 | -2.607 | -0.3007 | Yes |
| 76 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 35671 | -2.612 | -0.2839 | Yes |
| 77 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 35813 | -2.748 | -0.2692 | Yes |
| 78 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 35814 | -2.749 | -0.2508 | Yes |
| 79 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 35837 | -2.768 | -0.2328 | Yes |
| 80 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 35850 | -2.788 | -0.2144 | Yes |
| 81 | GSN | gelsolin [Source:HGNC Symbol;Acc:HGNC:4620] | 35954 | -2.875 | -0.1979 | Yes |
| 82 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 35972 | -2.894 | -0.1789 | Yes |
| 83 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36279 | -3.215 | -0.1656 | Yes |
| 84 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36290 | -3.231 | -0.1442 | Yes |
| 85 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36293 | -3.235 | -0.1225 | Yes |
| 86 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36367 | -3.347 | -0.1020 | Yes |
| 87 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36380 | -3.365 | -0.0798 | Yes |
| 88 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36496 | -3.483 | -0.0595 | Yes |
| 89 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36504 | -3.497 | -0.0362 | Yes |
| 90 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36548 | -3.570 | -0.0134 | Yes |
| 91 | PTGR1 | prostaglandin reductase 1 [Source:HGNC Symbol;Acc:HGNC:18429] | 36879 | -4.174 | 0.0057 | Yes |
