Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.88883746 |
| Normalized Enrichment Score (NES) | 2.154985 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 12 | 4.975 | 0.0258 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 18 | 4.924 | 0.0516 | Yes |
| 3 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 46 | 4.743 | 0.0758 | Yes |
| 4 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 70 | 4.590 | 0.0993 | Yes |
| 5 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 76 | 4.522 | 0.1230 | Yes |
| 6 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 91 | 4.447 | 0.1460 | Yes |
| 7 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 114 | 4.297 | 0.1680 | Yes |
| 8 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 128 | 4.232 | 0.1899 | Yes |
| 9 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 131 | 4.203 | 0.2119 | Yes |
| 10 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 145 | 4.155 | 0.2334 | Yes |
| 11 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 155 | 4.115 | 0.2548 | Yes |
| 12 | BCL2L1 | BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992] | 163 | 4.078 | 0.2761 | Yes |
| 13 | GK | glycerol kinase [Source:HGNC Symbol;Acc:HGNC:4289] | 233 | 3.755 | 0.2939 | Yes |
| 14 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 258 | 3.673 | 0.3126 | Yes |
| 15 | IL1RL1 | interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998] | 267 | 3.618 | 0.3314 | Yes |
| 16 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 273 | 3.595 | 0.3502 | Yes |
| 17 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 337 | 3.435 | 0.3665 | Yes |
| 18 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 338 | 3.434 | 0.3846 | Yes |
| 19 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 339 | 3.424 | 0.4026 | Yes |
| 20 | RGS16 | regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997] | 346 | 3.394 | 0.4203 | Yes |
| 21 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 347 | 3.370 | 0.4380 | Yes |
| 22 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 350 | 3.351 | 0.4556 | Yes |
| 23 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 353 | 3.350 | 0.4731 | Yes |
| 24 | CFLAR | CASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876] | 356 | 3.339 | 0.4907 | Yes |
| 25 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 357 | 3.333 | 0.5082 | Yes |
| 26 | RHOC | ras homolog family member C [Source:HGNC Symbol;Acc:HGNC:669] | 363 | 3.315 | 0.5255 | Yes |
| 27 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 390 | 3.237 | 0.5418 | Yes |
| 28 | IRGM | immunity related GTPase M [Source:HGNC Symbol;Acc:HGNC:29597] | 467 | 3.014 | 0.5556 | Yes |
| 29 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 537 | 2.855 | 0.5687 | Yes |
| 30 | MSR1 | macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376] | 557 | 2.811 | 0.5830 | Yes |
| 31 | STK10 | serine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388] | 558 | 2.808 | 0.5978 | Yes |
| 32 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 576 | 2.771 | 0.6119 | Yes |
| 33 | PNP | purine nucleoside phosphorylase [Source:HGNC Symbol;Acc:HGNC:7892] | 595 | 2.708 | 0.6256 | Yes |
| 34 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 680 | 2.637 | 0.6372 | Yes |
| 35 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 715 | 2.584 | 0.6499 | Yes |
| 36 | SRGN | serglycin [Source:HGNC Symbol;Acc:HGNC:9361] | 729 | 2.559 | 0.6630 | Yes |
| 37 | MYO10 | myosin X [Source:HGNC Symbol;Acc:HGNC:7593] | 741 | 2.538 | 0.6761 | Yes |
| 38 | IFRD1 | interferon related developmental regulator 1 [Source:HGNC Symbol;Acc:HGNC:5456] | 812 | 2.395 | 0.6868 | Yes |
| 39 | CLEC4D | C-type lectin domain family 4 member D [Source:HGNC Symbol;Acc:HGNC:14554] | 833 | 2.360 | 0.6986 | Yes |
| 40 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 836 | 2.354 | 0.7110 | Yes |
| 41 | ACSL4 | acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] | 907 | 2.278 | 0.7210 | Yes |
| 42 | APBB1IP | amyloid beta precursor protein binding family B member 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:17379] | 955 | 2.207 | 0.7314 | Yes |
| 43 | LCP2 | lymphocyte cytosolic protein 2 [Source:HGNC Symbol;Acc:HGNC:6529] | 956 | 2.205 | 0.7430 | Yes |
| 44 | ATF3 | activating transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:785] | 993 | 2.164 | 0.7534 | Yes |
| 45 | TGFB1 | transforming growth factor beta 1 [Source:HGNC Symbol;Acc:HGNC:11766] | 1030 | 2.110 | 0.7635 | Yes |
| 46 | DEGS1 | delta 4-desaturase, sphingolipid 1 [Source:HGNC Symbol;Acc:HGNC:13709] | 1033 | 2.108 | 0.7745 | Yes |
| 47 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 1076 | 2.054 | 0.7842 | Yes |
| 48 | ETF1 | eukaryotic translation termination factor 1 [Source:HGNC Symbol;Acc:HGNC:3477] | 1103 | 2.015 | 0.7941 | Yes |
| 49 | ADAR | adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225] | 1159 | 1.949 | 0.8029 | Yes |
| 50 | CLN3 | CLN3 lysosomal/endosomal transmembrane protein, battenin [Source:HGNC Symbol;Acc:HGNC:2074] | 1170 | 1.933 | 0.8128 | Yes |
| 51 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 1209 | 1.885 | 0.8216 | Yes |
| 52 | SLC20A1 | solute carrier family 20 member 1 [Source:HGNC Symbol;Acc:HGNC:10946] | 1377 | 1.839 | 0.8268 | Yes |
| 53 | RNF11 | ring finger protein 11 [Source:HGNC Symbol;Acc:HGNC:10056] | 1384 | 1.825 | 0.8362 | Yes |
| 54 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 1439 | 1.753 | 0.8440 | Yes |
| 55 | JUND | JunD proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6206] | 1459 | 1.736 | 0.8526 | Yes |
| 56 | HCLS1 | hematopoietic cell-specific Lyn substrate 1 [Source:HGNC Symbol;Acc:HGNC:4844] | 1483 | 1.717 | 0.8610 | Yes |
| 57 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 1704 | 1.553 | 0.8632 | Yes |
| 58 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 1774 | 1.506 | 0.8693 | Yes |
| 59 | EIF1 | eukaryotic translation initiation factor 1 [Source:HGNC Symbol;Acc:HGNC:3249] | 1925 | 1.395 | 0.8726 | Yes |
| 60 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 2051 | 1.318 | 0.8761 | Yes |
| 61 | WSB1 | WD repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:19221] | 2061 | 1.314 | 0.8828 | Yes |
| 62 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006] | 2206 | 1.234 | 0.8854 | Yes |
| 63 | TOP1 | DNA topoisomerase I [Source:HGNC Symbol;Acc:HGNC:11986] | 2316 | 1.215 | 0.8888 | Yes |
| 64 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 2792 | 1.009 | 0.8813 | No |
| 65 | SLC2A1 | solute carrier family 2 member 1 [Source:HGNC Symbol;Acc:HGNC:11005] | 2841 | 0.989 | 0.8852 | No |
| 66 | MLLT11 | MLLT11 transcription factor 7 cofactor [Source:HGNC Symbol;Acc:HGNC:16997] | 3056 | 0.902 | 0.8842 | No |
| 67 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 3993 | 0.581 | 0.8619 | No |
| 68 | MAP2K1 | mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840] | 4117 | 0.544 | 0.8615 | No |
| 69 | FCGR2B | Fc fragment of IgG receptor IIb [Source:HGNC Symbol;Acc:HGNC:3618] | 5725 | 0.184 | 0.8190 | No |
| 70 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6423 | 0.000 | 0.8002 | No |
| 71 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8970 | 0.000 | 0.7314 | No |
| 72 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 11589 | 0.000 | 0.6606 | No |
| 73 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 12443 | 0.000 | 0.6376 | No |
| 74 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13480 | 0.000 | 0.6096 | No |
| 75 | SLPI | secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092] | 22489 | 0.000 | 0.3662 | No |
| 76 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 24216 | 0.000 | 0.3195 | No |
| 77 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 28037 | 0.000 | 0.2163 | No |
| 78 | RCN1 | reticulocalbin 1 [Source:HGNC Symbol;Acc:HGNC:9934] | 29771 | -0.306 | 0.1711 | No |
| 79 | PRKCD | protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399] | 30258 | -0.420 | 0.1602 | No |
| 80 | KPNA3 | karyopherin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6396] | 30268 | -0.424 | 0.1621 | No |
| 81 | MAPKAPK2 | MAPK activated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:6887] | 30571 | -0.504 | 0.1566 | No |
| 82 | SAP30 | Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532] | 30580 | -0.507 | 0.1591 | No |
| 83 | PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase type 1 beta [Source:HGNC Symbol;Acc:HGNC:8995] | 30885 | -0.588 | 0.1540 | No |
| 84 | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 [Source:HGNC Symbol;Acc:HGNC:1987] | 31271 | -0.694 | 0.1472 | No |
| 85 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 34570 | -1.905 | 0.0681 | No |
