Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | REACTOME_DEFENSINS |
| Enrichment Score (ES) | 0.94762415 |
| Normalized Enrichment Score (NES) | 2.1495304 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 190 | 3.927 | 0.5070 | Yes |
| 2 | TLR1 | toll like receptor 1 [Source:HGNC Symbol;Acc:HGNC:11847] | 842 | 2.352 | 0.7961 | Yes |
| 3 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1942 | 1.389 | 0.9476 | Yes |
| 4 | DEFB4A | defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] | 7255 | 0.000 | 0.8042 | No |
| 5 | DEFB4B | defensin beta 4B [Source:HGNC Symbol;Acc:HGNC:30193] | 7256 | 0.000 | 0.8042 | No |
| 6 | ART1 | ADP-ribosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:723] | 7536 | 0.000 | 0.7967 | No |
| 7 | DEFB129 | defensin beta 129 [Source:HGNC Symbol;Acc:HGNC:16218] | 7570 | 0.000 | 0.7958 | No |
| 8 | DEFB128 | defensin beta 128 [Source:HGNC Symbol;Acc:HGNC:18106] | 7571 | 0.000 | 0.7958 | No |
| 9 | DEFB127 | defensin beta 127 [Source:HGNC Symbol;Acc:HGNC:16206] | 7572 | 0.000 | 0.7958 | No |
| 10 | DEFB126 | defensin beta 126 [Source:HGNC Symbol;Acc:HGNC:15900] | 7573 | 0.000 | 0.7958 | No |
| 11 | DEFB125 | defensin beta 125 [Source:HGNC Symbol;Acc:HGNC:18105] | 7574 | 0.000 | 0.7958 | No |
| 12 | DEFB124 | defensin beta 124 [Source:HGNC Symbol;Acc:HGNC:18104] | 7575 | 0.000 | 0.7958 | No |
| 13 | DEFB123 | defensin beta 123 [Source:HGNC Symbol;Acc:HGNC:18103] | 7576 | 0.000 | 0.7958 | No |
| 14 | DEFB121 | defensin beta 121 [Source:HGNC Symbol;Acc:HGNC:18101] | 7578 | 0.000 | 0.7958 | No |
| 15 | DEFB136 | defensin beta 136 [Source:HGNC Symbol;Acc:HGNC:34433] | 7583 | 0.000 | 0.7957 | No |
| 16 | DEFB135 | defensin beta 135 [Source:HGNC Symbol;Acc:HGNC:32400] | 7584 | 0.000 | 0.7957 | No |
| 17 | DEFB134 | defensin beta 134 [Source:HGNC Symbol;Acc:HGNC:32399] | 7585 | 0.000 | 0.7957 | No |
| 18 | DEFB133 | defensin beta 133 [Source:HGNC Symbol;Acc:HGNC:31331] | 7586 | 0.000 | 0.7957 | No |
| 19 | DEFB132 | defensin beta 132 [Source:HGNC Symbol;Acc:HGNC:33806] | 7587 | 0.000 | 0.7957 | No |
| 20 | DEFB119 | defensin beta 119 [Source:HGNC Symbol;Acc:HGNC:18099] | 7775 | 0.000 | 0.7906 | No |
| 21 | DEFB118 | defensin beta 118 [Source:HGNC Symbol;Acc:HGNC:16196] | 7776 | 0.000 | 0.7906 | No |
| 22 | DEFB116 | defensin beta 116 [Source:HGNC Symbol;Acc:HGNC:18097] | 7779 | 0.000 | 0.7906 | No |
| 23 | DEFB115 | defensin beta 115 [Source:HGNC Symbol;Acc:HGNC:18096] | 7782 | 0.000 | 0.7905 | No |
| 24 | DEFB114 | defensin beta 114 [Source:HGNC Symbol;Acc:HGNC:18095] | 7784 | 0.000 | 0.7905 | No |
| 25 | DEFB113 | defensin beta 113 [Source:HGNC Symbol;Acc:HGNC:18094] | 7785 | 0.000 | 0.7905 | No |
| 26 | DEFB112 | defensin beta 112 [Source:HGNC Symbol;Acc:HGNC:18093] | 7786 | 0.000 | 0.7905 | No |
| 27 | DEFB110 | defensin beta 110 [Source:HGNC Symbol;Acc:HGNC:18091] | 7788 | 0.000 | 0.7904 | No |
| 28 | DEFA1B | defensin alpha 1B [Source:HGNC Symbol;Acc:HGNC:33596] | 8898 | 0.000 | 0.7605 | No |
| 29 | CD4 | CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678] | 15735 | 0.000 | 0.5759 | No |
| 30 | DEFB1 | defensin beta 1 [Source:HGNC Symbol;Acc:HGNC:2766] | 20599 | 0.000 | 0.4447 | No |
| 31 | DEFA6 | defensin alpha 6 [Source:HGNC Symbol;Acc:HGNC:2765] | 20653 | 0.000 | 0.4432 | No |
| 32 | DEFA4 | defensin alpha 4 [Source:HGNC Symbol;Acc:HGNC:2763] | 20658 | 0.000 | 0.4431 | No |
| 33 | DEFA5 | defensin alpha 5 [Source:HGNC Symbol;Acc:HGNC:2764] | 20660 | 0.000 | 0.4431 | No |
| 34 | DEFA3 | defensin alpha 3 [Source:HGNC Symbol;Acc:HGNC:2762] | 20663 | 0.000 | 0.4430 | No |
| 35 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 20665 | 0.000 | 0.4430 | No |
| 36 | PRSS3 | serine protease 3 [Source:HGNC Symbol;Acc:HGNC:9486] | 22691 | 0.000 | 0.3883 | No |
| 37 | DEFB130A | defensin beta 130A [Source:HGNC Symbol;Acc:HGNC:18107] | 27060 | 0.000 | 0.2704 | No |
| 38 | DEFB130B | defensin beta 130B [Source:HGNC Symbol;Acc:HGNC:39814] | 27062 | 0.000 | 0.2704 | No |
| 39 | DEFB131A | defensin beta 131A [Source:HGNC Symbol;Acc:HGNC:18108] | 27063 | 0.000 | 0.2704 | No |
| 40 | DEFB103A | defensin beta 103A [Source:HGNC Symbol;Acc:HGNC:15967] | 28087 | 0.000 | 0.2428 | No |
| 41 | DEFB103B | defensin beta 103B [Source:HGNC Symbol;Acc:HGNC:31702] | 28090 | 0.000 | 0.2427 | No |
| 42 | DEFB104B | defensin beta 104B [Source:HGNC Symbol;Acc:HGNC:26165] | 28108 | 0.000 | 0.2423 | No |
| 43 | DEFB104A | defensin beta 104A [Source:HGNC Symbol;Acc:HGNC:18115] | 28110 | 0.000 | 0.2422 | No |
| 44 | DEFB105A | defensin beta 105A [Source:HGNC Symbol;Acc:HGNC:18087] | 28124 | 0.000 | 0.2419 | No |
| 45 | DEFB105B | defensin beta 105B [Source:HGNC Symbol;Acc:HGNC:29930] | 28125 | 0.000 | 0.2419 | No |
| 46 | CCR6 | C-C motif chemokine receptor 6 [Source:HGNC Symbol;Acc:HGNC:1607] | 28140 | 0.000 | 0.2415 | No |
| 47 | DEFB106B | defensin beta 106B [Source:HGNC Symbol;Acc:HGNC:28879] | 28149 | 0.000 | 0.2413 | No |
| 48 | DEFB106A | defensin beta 106A [Source:HGNC Symbol;Acc:HGNC:18088] | 28157 | 0.000 | 0.2411 | No |
| 49 | DEFB107A | defensin beta 107A [Source:HGNC Symbol;Acc:HGNC:18086] | 28178 | 0.000 | 0.2406 | No |
| 50 | DEFB107B | defensin beta 107B [Source:HGNC Symbol;Acc:HGNC:31918] | 28180 | 0.000 | 0.2405 | No |
| 51 | DEFB108B | defensin beta 108B [Source:HGNC Symbol;Acc:HGNC:29966] | 28209 | 0.000 | 0.2398 | No |
