Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | REACTOME_INTERLEUKIN_10_SIGNALING |
| Enrichment Score (ES) | 0.8683146 |
| Normalized Enrichment Score (NES) | 1.9460416 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.122743E-4 |
| FWER p-Value | 0.005 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.996 | 0.0616 | Yes |
| 2 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 12 | 4.975 | 0.1228 | Yes |
| 3 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 17 | 4.929 | 0.1835 | Yes |
| 4 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 18 | 4.924 | 0.2443 | Yes |
| 5 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 20 | 4.911 | 0.3049 | Yes |
| 6 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 22 | 4.908 | 0.3655 | Yes |
| 7 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 25 | 4.883 | 0.4257 | Yes |
| 8 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 43 | 4.784 | 0.4843 | Yes |
| 9 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 46 | 4.743 | 0.5428 | Yes |
| 10 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 56 | 4.661 | 0.6001 | Yes |
| 11 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 123 | 4.245 | 0.6507 | Yes |
| 12 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 128 | 4.232 | 0.7028 | Yes |
| 13 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 190 | 3.927 | 0.7497 | Yes |
| 14 | STAT3 | signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364] | 688 | 2.622 | 0.7686 | Yes |
| 15 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 722 | 2.579 | 0.7996 | Yes |
| 16 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 859 | 2.334 | 0.8247 | Yes |
| 17 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 889 | 2.298 | 0.8523 | Yes |
| 18 | TNFRSF1A | TNF receptor superfamily member 1A [Source:HGNC Symbol;Acc:HGNC:11916] | 1177 | 1.926 | 0.8683 | Yes |
| 19 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 2324 | 1.212 | 0.8523 | No |
| 20 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 2674 | 1.056 | 0.8560 | No |
| 21 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 3931 | 0.597 | 0.8294 | No |
| 22 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 5635 | 0.213 | 0.7861 | No |
| 23 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6413 | 0.000 | 0.7651 | No |
| 24 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6424 | 0.000 | 0.7648 | No |
| 25 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6427 | 0.000 | 0.7648 | No |
| 26 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 13841 | 0.000 | 0.5647 | No |
| 27 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14840 | 0.000 | 0.5377 | No |
| 28 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14842 | 0.000 | 0.5377 | No |
| 29 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15885 | 0.000 | 0.5096 | No |
| 30 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 15886 | 0.000 | 0.5096 | No |
| 31 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 17775 | 0.000 | 0.4586 | No |
| 32 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18323 | 0.000 | 0.4438 | No |
| 33 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19553 | 0.000 | 0.4107 | No |
| 34 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19562 | 0.000 | 0.4105 | No |
| 35 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19565 | 0.000 | 0.4104 | No |
| 36 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 21697 | 0.000 | 0.3529 | No |
| 37 | FCER2 | Fc fragment of IgE receptor II [Source:HGNC Symbol;Acc:HGNC:3612] | 23438 | 0.000 | 0.3059 | No |
| 38 | IL12A | interleukin 12A [Source:HGNC Symbol;Acc:HGNC:5969] | 24406 | 0.000 | 0.2798 | No |
| 39 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 28037 | 0.000 | 0.1818 | No |
| 40 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 28039 | 0.000 | 0.1818 | No |
| 41 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 28224 | 0.000 | 0.1768 | No |
| 42 | CD80 | CD80 molecule [Source:HGNC Symbol;Acc:HGNC:1700] | 28227 | 0.000 | 0.1768 | No |
| 43 | TYK2 | tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440] | 29177 | -0.170 | 0.1532 | No |
| 44 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 33584 | -1.451 | 0.0522 | No |
| 45 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 33602 | -1.451 | 0.0697 | No |
| 46 | IL10RB | interleukin 10 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:5965] | 34718 | -1.982 | 0.0640 | No |
