Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | WORSCHECH_TUMOR_REJECTION_UP |
| Enrichment Score (ES) | 0.8183319 |
| Normalized Enrichment Score (NES) | 1.8945295 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0023508812 |
| FWER p-Value | 0.026 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.996 | 0.0812 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 20 | 4.911 | 0.1606 | Yes |
| 3 | IL4I1 | interleukin 4 induced 1 [Source:HGNC Symbol;Acc:HGNC:19094] | 32 | 4.846 | 0.2391 | Yes |
| 4 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 43 | 4.784 | 0.3167 | Yes |
| 5 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 45 | 4.752 | 0.3939 | Yes |
| 6 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 46 | 4.743 | 0.4711 | Yes |
| 7 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 108 | 4.324 | 0.5397 | Yes |
| 8 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 226 | 3.782 | 0.5981 | Yes |
| 9 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 413 | 3.159 | 0.6445 | Yes |
| 10 | MSR1 | macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376] | 557 | 2.811 | 0.6863 | Yes |
| 11 | TLR6 | toll like receptor 6 [Source:HGNC Symbol;Acc:HGNC:16711] | 951 | 2.214 | 0.7117 | Yes |
| 12 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 1047 | 2.089 | 0.7431 | Yes |
| 13 | CCR10 | C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474] | 1129 | 1.974 | 0.7730 | Yes |
| 14 | ALCAM | activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400] | 1484 | 1.717 | 0.7914 | Yes |
| 15 | NKRF | NFKB repressing factor [Source:HGNC Symbol;Acc:HGNC:19374] | 1951 | 1.382 | 0.8013 | Yes |
| 16 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 2101 | 1.295 | 0.8183 | Yes |
| 17 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 3684 | 0.681 | 0.7867 | No |
| 18 | CKLF | chemokine like factor [Source:HGNC Symbol;Acc:HGNC:13253] | 4134 | 0.539 | 0.7833 | No |
| 19 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 5250 | 0.239 | 0.7571 | No |
| 20 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6394 | 0.000 | 0.7262 | No |
| 21 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6423 | 0.000 | 0.7255 | No |
| 22 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6424 | 0.000 | 0.7255 | No |
| 23 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8858 | 0.000 | 0.6598 | No |
| 24 | LY6H | lymphocyte antigen 6 family member H [Source:HGNC Symbol;Acc:HGNC:6728] | 9341 | 0.000 | 0.6468 | No |
| 25 | TNFRSF4 | TNF receptor superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:11918] | 9799 | 0.000 | 0.6344 | No |
| 26 | ACKR1 | atypical chemokine receptor 1 (Duffy blood group) [Source:HGNC Symbol;Acc:HGNC:4035] | 11188 | 0.000 | 0.5969 | No |
| 27 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 11589 | 0.000 | 0.5861 | No |
| 28 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12314 | 0.000 | 0.5666 | No |
| 29 | TNFSF11 | TNF superfamily member 11 [Source:HGNC Symbol;Acc:HGNC:11926] | 12447 | 0.000 | 0.5630 | No |
| 30 | TCL1B | T cell leukemia/lymphoma 1B [Source:HGNC Symbol;Acc:HGNC:11649] | 13100 | 0.000 | 0.5454 | No |
| 31 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13480 | 0.000 | 0.5352 | No |
| 32 | IL31 | interleukin 31 [Source:HGNC Symbol;Acc:HGNC:19372] | 13885 | 0.000 | 0.5243 | No |
| 33 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 13957 | 0.000 | 0.5223 | No |
| 34 | TLX1 | T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056] | 14400 | 0.000 | 0.5104 | No |
| 35 | EBF4 | EBF family member 4 [Source:HGNC Symbol;Acc:HGNC:29278] | 15105 | 0.000 | 0.4914 | No |
| 36 | IL17RB | interleukin 17 receptor B [Source:HGNC Symbol;Acc:HGNC:18015] | 15175 | 0.000 | 0.4895 | No |
| 37 | IL36G | interleukin 36 gamma [Source:HGNC Symbol;Acc:HGNC:15741] | 15648 | 0.000 | 0.4768 | No |
| 38 | CLEC10A | C-type lectin domain containing 10A [Source:HGNC Symbol;Acc:HGNC:16916] | 15744 | 0.000 | 0.4742 | No |
| 39 | IL23R | interleukin 23 receptor [Source:HGNC Symbol;Acc:HGNC:19100] | 15881 | 0.000 | 0.4705 | No |
| 40 | IL5 | interleukin 5 [Source:HGNC Symbol;Acc:HGNC:6016] | 17776 | 0.000 | 0.4194 | No |
| 41 | IL7 | interleukin 7 [Source:HGNC Symbol;Acc:HGNC:6023] | 17777 | 0.000 | 0.4194 | No |
| 42 | ITK | IL2 inducible T cell kinase [Source:HGNC Symbol;Acc:HGNC:6171] | 17849 | 0.000 | 0.4175 | No |
| 43 | IFNA13 | interferon alpha 13 [Source:HGNC Symbol;Acc:HGNC:5419] | 18247 | 0.000 | 0.4068 | No |
| 44 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 19000 | 0.000 | 0.3864 | No |
| 45 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19564 | 0.000 | 0.3712 | No |
| 46 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19565 | 0.000 | 0.3712 | No |
| 47 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 21120 | 0.000 | 0.3293 | No |
| 48 | IL17F | interleukin 17F [Source:HGNC Symbol;Acc:HGNC:16404] | 24467 | 0.000 | 0.2389 | No |
| 49 | FASLG | Fas ligand [Source:HGNC Symbol;Acc:HGNC:11936] | 25034 | 0.000 | 0.2236 | No |
| 50 | IFNG | interferon gamma [Source:HGNC Symbol;Acc:HGNC:5438] | 25600 | 0.000 | 0.2084 | No |
| 51 | IRF6 | interferon regulatory factor 6 [Source:HGNC Symbol;Acc:HGNC:6121] | 26698 | 0.000 | 0.1787 | No |
| 52 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 28028 | 0.000 | 0.1429 | No |
| 53 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 28040 | 0.000 | 0.1426 | No |
| 54 | JCHAIN | joining chain of multimeric IgA and IgM [Source:HGNC Symbol;Acc:HGNC:5713] | 28448 | 0.000 | 0.1316 | No |
| 55 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 29282 | -0.193 | 0.1122 | No |
| 56 | STAT6 | signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368] | 29329 | -0.204 | 0.1143 | No |
| 57 | TAGAP | T cell activation RhoGTPase activating protein [Source:HGNC Symbol;Acc:HGNC:15669] | 29690 | -0.287 | 0.1092 | No |
| 58 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 30450 | -0.479 | 0.0965 | No |
| 59 | NKIRAS2 | NFKB inhibitor interacting Ras like 2 [Source:HGNC Symbol;Acc:HGNC:17898] | 31905 | -0.875 | 0.0715 | No |
| 60 | IRF4 | interferon regulatory factor 4 [Source:HGNC Symbol;Acc:HGNC:6119] | 32152 | -0.963 | 0.0805 | No |
| 61 | NFAT5 | nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774] | 32297 | -1.022 | 0.0933 | No |
| 62 | TLR4 | toll like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850] | 35071 | -2.223 | 0.0545 | No |
