Fig 1: Enrichment plot: MIR3972
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | MIR3972 |
| Enrichment Score (ES) | 0.5572727 |
| Normalized Enrichment Score (NES) | 1.3254293 |
| Nominal p-value | 0.044692736 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 70 | 4.590 | 0.0782 | Yes |
| 2 | ABCA1 | ATP binding cassette subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:29] | 148 | 4.135 | 0.1484 | Yes |
| 3 | PPP1R14C | protein phosphatase 1 regulatory inhibitor subunit 14C [Source:HGNC Symbol;Acc:HGNC:14952] | 437 | 3.149 | 0.1956 | Yes |
| 4 | ACTG1 | actin gamma 1 [Source:HGNC Symbol;Acc:HGNC:144] | 516 | 2.906 | 0.2442 | Yes |
| 5 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 859 | 2.334 | 0.2757 | Yes |
| 6 | SLC38A1 | solute carrier family 38 member 1 [Source:HGNC Symbol;Acc:HGNC:13447] | 1558 | 1.663 | 0.2859 | Yes |
| 7 | RRN3 | RRN3 homolog, RNA polymerase I transcription factor [Source:HGNC Symbol;Acc:HGNC:30346] | 1682 | 1.572 | 0.3100 | Yes |
| 8 | PSMD12 | proteasome 26S subunit, non-ATPase 12 [Source:HGNC Symbol;Acc:HGNC:9557] | 2130 | 1.275 | 0.3202 | Yes |
| 9 | CDK14 | cyclin dependent kinase 14 [Source:HGNC Symbol;Acc:HGNC:8883] | 2151 | 1.265 | 0.3418 | Yes |
| 10 | ZDHHC21 | zinc finger DHHC-type palmitoyltransferase 21 [Source:HGNC Symbol;Acc:HGNC:20750] | 2153 | 1.264 | 0.3638 | Yes |
| 11 | CTNND1 | catenin delta 1 [Source:HGNC Symbol;Acc:HGNC:2515] | 2307 | 1.218 | 0.3810 | Yes |
| 12 | TMEM87A | transmembrane protein 87A [Source:HGNC Symbol;Acc:HGNC:24522] | 2440 | 1.153 | 0.3975 | Yes |
| 13 | MAX | MYC associated factor X [Source:HGNC Symbol;Acc:HGNC:6913] | 2462 | 1.142 | 0.4169 | Yes |
| 14 | LUZP1 | leucine zipper protein 1 [Source:HGNC Symbol;Acc:HGNC:14985] | 2592 | 1.088 | 0.4324 | Yes |
| 15 | PAK2 | p21 (RAC1) activated kinase 2 [Source:HGNC Symbol;Acc:HGNC:8591] | 2724 | 1.041 | 0.4471 | Yes |
| 16 | ZBTB43 | zinc finger and BTB domain containing 43 [Source:HGNC Symbol;Acc:HGNC:17908] | 2920 | 0.947 | 0.4583 | Yes |
| 17 | EGLN2 | egl-9 family hypoxia inducible factor 2 [Source:HGNC Symbol;Acc:HGNC:14660] | 2977 | 0.938 | 0.4732 | Yes |
| 18 | ZBTB34 | zinc finger and BTB domain containing 34 [Source:HGNC Symbol;Acc:HGNC:31446] | 3040 | 0.909 | 0.4874 | Yes |
| 19 | ANAPC16 | anaphase promoting complex subunit 16 [Source:HGNC Symbol;Acc:HGNC:26976] | 3233 | 0.832 | 0.4967 | Yes |
| 20 | NDFIP2 | Nedd4 family interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:18537] | 3574 | 0.712 | 0.5000 | Yes |
| 21 | DICER1 | dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098] | 3781 | 0.649 | 0.5057 | Yes |
| 22 | NUMBL | NUMB like endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8061] | 3929 | 0.597 | 0.5122 | Yes |
| 23 | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:11187] | 4016 | 0.573 | 0.5199 | Yes |
| 24 | DMTF1 | cyclin D binding myb like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:14603] | 4137 | 0.539 | 0.5260 | Yes |
| 25 | SELENOT | selenoprotein T [Source:HGNC Symbol;Acc:HGNC:18136] | 4188 | 0.523 | 0.5338 | Yes |
| 26 | EIF4E2 | eukaryotic translation initiation factor 4E family member 2 [Source:HGNC Symbol;Acc:HGNC:3293] | 4401 | 0.464 | 0.5362 | Yes |
| 27 | FTSJ1 | FtsJ RNA 2'-O-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:13254] | 4409 | 0.462 | 0.5441 | Yes |
| 28 | KDM6A | lysine demethylase 6A [Source:HGNC Symbol;Acc:HGNC:12637] | 4656 | 0.388 | 0.5442 | Yes |
| 29 | OSBPL11 | oxysterol binding protein like 11 [Source:HGNC Symbol;Acc:HGNC:16397] | 4733 | 0.365 | 0.5485 | Yes |
| 30 | RRP1B | ribosomal RNA processing 1B [Source:HGNC Symbol;Acc:HGNC:23818] | 4929 | 0.309 | 0.5486 | Yes |
| 31 | EML4 | EMAP like 4 [Source:HGNC Symbol;Acc:HGNC:1316] | 4982 | 0.293 | 0.5523 | Yes |
| 32 | ZDHHC18 | zinc finger DHHC-type palmitoyltransferase 18 [Source:HGNC Symbol;Acc:HGNC:20712] | 5072 | 0.266 | 0.5546 | Yes |
| 33 | CNST | consortin, connexin sorting protein [Source:HGNC Symbol;Acc:HGNC:26486] | 5133 | 0.247 | 0.5573 | Yes |
| 34 | ABLIM1 | actin binding LIM protein 1 [Source:HGNC Symbol;Acc:HGNC:78] | 7107 | 0.000 | 0.5040 | No |
| 35 | PLPPR4 | phospholipid phosphatase related 4 [Source:HGNC Symbol;Acc:HGNC:23496] | 7731 | 0.000 | 0.4872 | No |
| 36 | MCTP2 | multiple C2 and transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25636] | 8047 | 0.000 | 0.4786 | No |
| 37 | COLEC10 | collectin subfamily member 10 [Source:HGNC Symbol;Acc:HGNC:2220] | 8552 | 0.000 | 0.4650 | No |
| 38 | PTPN20 | protein tyrosine phosphatase non-receptor type 20 [Source:HGNC Symbol;Acc:HGNC:23423] | 9512 | 0.000 | 0.4391 | No |
| 39 | ZNF195 | zinc finger protein 195 [Source:HGNC Symbol;Acc:HGNC:12986] | 9659 | 0.000 | 0.4352 | No |
| 40 | TOX | thymocyte selection associated high mobility group box [Source:HGNC Symbol;Acc:HGNC:18988] | 12679 | 0.000 | 0.3536 | No |
| 41 | LILRA5 | leukocyte immunoglobulin like receptor A5 [Source:HGNC Symbol;Acc:HGNC:16309] | 13473 | 0.000 | 0.3322 | No |
| 42 | NDST3 | N-deacetylase and N-sulfotransferase 3 [Source:HGNC Symbol;Acc:HGNC:7682] | 13570 | 0.000 | 0.3296 | No |
| 43 | TMEM215 | transmembrane protein 215 [Source:HGNC Symbol;Acc:HGNC:33816] | 13983 | 0.000 | 0.3185 | No |
| 44 | EFNA5 | ephrin A5 [Source:HGNC Symbol;Acc:HGNC:3225] | 14389 | 0.000 | 0.3075 | No |
| 45 | PAK5 | p21 (RAC1) activated kinase 5 [Source:HGNC Symbol;Acc:HGNC:15916] | 14791 | 0.000 | 0.2967 | No |
| 46 | SLC18A2 | solute carrier family 18 member A2 [Source:HGNC Symbol;Acc:HGNC:10935] | 15352 | 0.000 | 0.2816 | No |
| 47 | CRISPLD1 | cysteine rich secretory protein LCCL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18206] | 15628 | 0.000 | 0.2742 | No |
| 48 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16219 | 0.000 | 0.2582 | No |
| 49 | HNF4A | hepatocyte nuclear factor 4 alpha [Source:HGNC Symbol;Acc:HGNC:5024] | 17709 | 0.000 | 0.2180 | No |
| 50 | CHSY3 | chondroitin sulfate synthase 3 [Source:HGNC Symbol;Acc:HGNC:24293] | 18838 | 0.000 | 0.1875 | No |
| 51 | BNIP5 | BCL2 interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:33769] | 20188 | 0.000 | 0.1511 | No |
| 52 | SULT4A1 | sulfotransferase family 4A member 1 [Source:HGNC Symbol;Acc:HGNC:14903] | 20862 | 0.000 | 0.1329 | No |
| 53 | LAMP5 | lysosomal associated membrane protein family member 5 [Source:HGNC Symbol;Acc:HGNC:16097] | 21702 | 0.000 | 0.1103 | No |
| 54 | MS4A12 | membrane spanning 4-domains A12 [Source:HGNC Symbol;Acc:HGNC:13370] | 23398 | 0.000 | 0.0645 | No |
| 55 | SHE | Src homology 2 domain containing E [Source:HGNC Symbol;Acc:HGNC:27004] | 25690 | 0.000 | 0.0026 | No |
| 56 | ZNF365 | zinc finger protein 365 [Source:HGNC Symbol;Acc:HGNC:18194] | 27519 | 0.000 | -0.0468 | No |
| 57 | MED23 | mediator complex subunit 23 [Source:HGNC Symbol;Acc:HGNC:2372] | 28764 | -0.063 | -0.0793 | No |
| 58 | ARID4B | AT-rich interaction domain 4B [Source:HGNC Symbol;Acc:HGNC:15550] | 29809 | -0.316 | -0.1020 | No |
| 59 | RALBP1 | ralA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9841] | 30323 | -0.439 | -0.1082 | No |
| 60 | CDH5 | cadherin 5 [Source:HGNC Symbol;Acc:HGNC:1764] | 30488 | -0.480 | -0.1042 | No |
| 61 | LRP4 | LDL receptor related protein 4 [Source:HGNC Symbol;Acc:HGNC:6696] | 30900 | -0.591 | -0.1050 | No |
| 62 | NR2C1 | nuclear receptor subfamily 2 group C member 1 [Source:HGNC Symbol;Acc:HGNC:7971] | 31098 | -0.644 | -0.0991 | No |
| 63 | TLE3 | TLE family member 3, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11839] | 31720 | -0.809 | -0.1017 | No |
| 64 | SRPK2 | SRSF protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:11306] | 32835 | -1.194 | -0.1109 | No |
| 65 | TMEM263 | transmembrane protein 263 [Source:HGNC Symbol;Acc:HGNC:28281] | 32969 | -1.249 | -0.0927 | No |
| 66 | MAN2B2 | mannosidase alpha class 2B member 2 [Source:HGNC Symbol;Acc:HGNC:29623] | 33629 | -1.451 | -0.0852 | No |
| 67 | FMO5 | flavin containing dimethylaniline monoxygenase 5 [Source:HGNC Symbol;Acc:HGNC:3773] | 34245 | -1.738 | -0.0715 | No |
| 68 | BICRAL | BRD4 interacting chromatin remodeling complex associated protein like [Source:HGNC Symbol;Acc:HGNC:21111] | 34981 | -2.161 | -0.0536 | No |
| 69 | ZFHX4 | zinc finger homeobox 4 [Source:HGNC Symbol;Acc:HGNC:30939] | 35416 | -2.405 | -0.0233 | No |
| 70 | LRRC8C | leucine rich repeat containing 8 VRAC subunit C [Source:HGNC Symbol;Acc:HGNC:25075] | 36762 | -3.923 | 0.0089 | No |
