Fig 1: Enrichment plot: MIR6855_3P
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | MIR6855_3P |
| Enrichment Score (ES) | 0.59834766 |
| Normalized Enrichment Score (NES) | 1.3415388 |
| Nominal p-value | 0.037815128 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MAP1B | microtubule associated protein 1B [Source:HGNC Symbol;Acc:HGNC:6836] | 159 | 4.096 | 0.0979 | Yes |
| 2 | P3H2 | prolyl 3-hydroxylase 2 [Source:HGNC Symbol;Acc:HGNC:19317] | 552 | 2.819 | 0.1577 | Yes |
| 3 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 786 | 2.439 | 0.2123 | Yes |
| 4 | CLEC4D | C-type lectin domain family 4 member D [Source:HGNC Symbol;Acc:HGNC:14554] | 833 | 2.360 | 0.2699 | Yes |
| 5 | DCUN1D3 | defective in cullin neddylation 1 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28734] | 896 | 2.291 | 0.3255 | Yes |
| 6 | LCP2 | lymphocyte cytosolic protein 2 [Source:HGNC Symbol;Acc:HGNC:6529] | 956 | 2.205 | 0.3789 | Yes |
| 7 | MAPK10 | mitogen-activated protein kinase 10 [Source:HGNC Symbol;Acc:HGNC:6872] | 1220 | 1.877 | 0.4186 | Yes |
| 8 | SLC4A5 | solute carrier family 4 member 5 [Source:HGNC Symbol;Acc:HGNC:18168] | 1671 | 1.582 | 0.4460 | Yes |
| 9 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 1704 | 1.553 | 0.4839 | Yes |
| 10 | GSAP | gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042] | 1789 | 1.495 | 0.5189 | Yes |
| 11 | GAN | gigaxonin [Source:HGNC Symbol;Acc:HGNC:4137] | 2419 | 1.162 | 0.5309 | Yes |
| 12 | CLDND1 | claudin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1322] | 2549 | 1.112 | 0.5552 | Yes |
| 13 | VKORC1L1 | vitamin K epoxide reductase complex subunit 1 like 1 [Source:HGNC Symbol;Acc:HGNC:21492] | 2624 | 1.078 | 0.5801 | Yes |
| 14 | HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:HGNC:5033] | 2856 | 0.982 | 0.5983 | Yes |
| 15 | C1orf50 | chromosome 1 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:28795] | 4588 | 0.409 | 0.5618 | No |
| 16 | PITPNB | phosphatidylinositol transfer protein beta [Source:HGNC Symbol;Acc:HGNC:9002] | 5028 | 0.280 | 0.5570 | No |
| 17 | PNPLA1 | patatin like phospholipase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21246] | 8283 | 0.000 | 0.4691 | No |
| 18 | KCNJ3 | potassium inwardly rectifying channel subfamily J member 3 [Source:HGNC Symbol;Acc:HGNC:6264] | 9876 | 0.000 | 0.4262 | No |
| 19 | MBOAT2 | membrane bound O-acyltransferase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25193] | 11598 | 0.000 | 0.3797 | No |
| 20 | PROZ | protein Z, vitamin K dependent plasma glycoprotein [Source:HGNC Symbol;Acc:HGNC:9460] | 11705 | 0.000 | 0.3768 | No |
| 21 | PDZD2 | PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18486] | 12078 | 0.000 | 0.3668 | No |
| 22 | BICD1 | BICD cargo adaptor 1 [Source:HGNC Symbol;Acc:HGNC:1049] | 12399 | 0.000 | 0.3582 | No |
| 23 | GLRA2 | glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327] | 12960 | 0.000 | 0.3430 | No |
| 24 | MYL1 | myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:7582] | 14469 | 0.000 | 0.3023 | No |
| 25 | RGS7 | regulator of G protein signaling 7 [Source:HGNC Symbol;Acc:HGNC:10003] | 14832 | 0.000 | 0.2926 | No |
| 26 | SV2C | synaptic vesicle glycoprotein 2C [Source:HGNC Symbol;Acc:HGNC:30670] | 15721 | 0.000 | 0.2686 | No |
| 27 | MDH1B | malate dehydrogenase 1B [Source:HGNC Symbol;Acc:HGNC:17836] | 16349 | 0.000 | 0.2517 | No |
| 28 | L3MBTL1 | L3MBTL histone methyl-lysine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:15905] | 17662 | 0.000 | 0.2162 | No |
| 29 | CPS1 | carbamoyl-phosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:2323] | 20847 | 0.000 | 0.1303 | No |
| 30 | MYOCD | myocardin [Source:HGNC Symbol;Acc:HGNC:16067] | 21555 | 0.000 | 0.1112 | No |
| 31 | OCLN | occludin [Source:HGNC Symbol;Acc:HGNC:8104] | 23552 | 0.000 | 0.0573 | No |
| 32 | SPZ1 | spermatogenic leucine zipper 1 [Source:HGNC Symbol;Acc:HGNC:30721] | 23863 | 0.000 | 0.0489 | No |
| 33 | FMO2 | flavin containing dimethylaniline monoxygenase 2 [Source:HGNC Symbol;Acc:HGNC:3770] | 24598 | 0.000 | 0.0291 | No |
| 34 | ESYT3 | extended synaptotagmin 3 [Source:HGNC Symbol;Acc:HGNC:24295] | 26594 | 0.000 | -0.0247 | No |
| 35 | ZNF594 | zinc finger protein 594 [Source:HGNC Symbol;Acc:HGNC:29392] | 26795 | 0.000 | -0.0301 | No |
| 36 | NIPBL | NIPBL cohesin loading factor [Source:HGNC Symbol;Acc:HGNC:28862] | 28924 | -0.104 | -0.0850 | No |
| 37 | CLK4 | CDC like kinase 4 [Source:HGNC Symbol;Acc:HGNC:13659] | 29025 | -0.130 | -0.0844 | No |
| 38 | LSM14A | LSM14A mRNA processing body assembly factor [Source:HGNC Symbol;Acc:HGNC:24489] | 29109 | -0.149 | -0.0829 | No |
| 39 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 29282 | -0.193 | -0.0828 | No |
| 40 | OSGEPL1 | O-sialoglycoprotein endopeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:23075] | 30249 | -0.417 | -0.0984 | No |
| 41 | NHLRC3 | NHL repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:33751] | 30604 | -0.514 | -0.0952 | No |
| 42 | KAT6B | lysine acetyltransferase 6B [Source:HGNC Symbol;Acc:HGNC:17582] | 32231 | -0.998 | -0.1141 | No |
| 43 | PM20D2 | peptidase M20 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21408] | 32343 | -1.023 | -0.0916 | No |
| 44 | TK2 | thymidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:11831] | 32894 | -1.216 | -0.0761 | No |
| 45 | MBNL1 | muscleblind like splicing regulator 1 [Source:HGNC Symbol;Acc:HGNC:6923] | 32915 | -1.228 | -0.0460 | No |
| 46 | ZNF25 | zinc finger protein 25 [Source:HGNC Symbol;Acc:HGNC:13043] | 33482 | -1.451 | -0.0250 | No |
| 47 | ICOS | inducible T cell costimulator [Source:HGNC Symbol;Acc:HGNC:5351] | 33625 | -1.451 | 0.0073 | No |
| 48 | MEAK7 | MTOR associated protein, eak-7 homolog [Source:HGNC Symbol;Acc:HGNC:29325] | 36474 | -3.453 | 0.0166 | No |
