Fig 1: Enrichment plot: PER1_TARGET_GENES
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | PER1_TARGET_GENES |
| Enrichment Score (ES) | 0.62473726 |
| Normalized Enrichment Score (NES) | 1.2734843 |
| Nominal p-value | 0.13475177 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SNORD12 | small nucleolar RNA, C/D box 12 [Source:HGNC Symbol;Acc:HGNC:32708] | 7 | 4.988 | 0.2069 | Yes |
| 2 | GAS5 | growth arrest specific 5 [Source:HGNC Symbol;Acc:HGNC:16355] | 194 | 3.903 | 0.3640 | Yes |
| 3 | SNORD45A | small nucleolar RNA, C/D box 45A [Source:HGNC Symbol;Acc:HGNC:10184] | 602 | 2.696 | 0.4650 | Yes |
| 4 | SFPQ | splicing factor proline and glutamine rich [Source:HGNC Symbol;Acc:HGNC:10774] | 1438 | 1.753 | 0.5153 | Yes |
| 5 | FST | follistatin [Source:HGNC Symbol;Acc:HGNC:3971] | 1814 | 1.473 | 0.5663 | Yes |
| 6 | SLC38A2 | solute carrier family 38 member 2 [Source:HGNC Symbol;Acc:HGNC:13448] | 3043 | 0.908 | 0.5709 | Yes |
| 7 | SRSF1 | serine and arginine rich splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:10780] | 3419 | 0.766 | 0.5926 | Yes |
| 8 | RABGGTB | Rab geranylgeranyltransferase subunit beta [Source:HGNC Symbol;Acc:HGNC:9796] | 3874 | 0.615 | 0.6058 | Yes |
| 9 | RBM39 | RNA binding motif protein 39 [Source:HGNC Symbol;Acc:HGNC:15923] | 4048 | 0.568 | 0.6247 | Yes |
| 10 | HNRNPK | heterogeneous nuclear ribonucleoprotein K [Source:HGNC Symbol;Acc:HGNC:5044] | 4898 | 0.318 | 0.6150 | No |
| 11 | EIF4A2 | eukaryotic translation initiation factor 4A2 [Source:HGNC Symbol;Acc:HGNC:3284] | 5098 | 0.258 | 0.6203 | No |
| 12 | HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 [Source:HGNC Symbol;Acc:HGNC:5041] | 5660 | 0.201 | 0.6136 | No |
| 13 | VPS52 | VPS52 subunit of GARP complex [Source:HGNC Symbol;Acc:HGNC:10518] | 6244 | 0.030 | 0.5991 | No |
| 14 | RPL17 | ribosomal protein L17 [Source:HGNC Symbol;Acc:HGNC:10307] | 6303 | 0.013 | 0.5980 | No |
| 15 | SNORA81 | small nucleolar RNA, H/ACA box 81 [Source:HGNC Symbol;Acc:HGNC:32667] | 16134 | 0.000 | 0.3328 | No |
| 16 | SNORA63 | small nucleolar RNA, H/ACA box 63 [Source:HGNC Symbol;Acc:HGNC:10106] | 16166 | 0.000 | 0.3319 | No |
| 17 | NTS | neurotensin [Source:HGNC Symbol;Acc:HGNC:8038] | 19530 | 0.000 | 0.2412 | No |
| 18 | SNORD12B | small nucleolar RNA, C/D box 12B [Source:HGNC Symbol;Acc:HGNC:33573] | 24138 | 0.000 | 0.1169 | No |
| 19 | ZNF773 | zinc finger protein 773 [Source:HGNC Symbol;Acc:HGNC:30487] | 25972 | 0.000 | 0.0674 | No |
| 20 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 28591 | -0.018 | -0.0024 | No |
| 21 | SGK1 | serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810] | 28803 | -0.072 | -0.0051 | No |
| 22 | EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 [Source:HGNC Symbol;Acc:HGNC:3189] | 28934 | -0.106 | -0.0042 | No |
| 23 | RPL34 | ribosomal protein L34 [Source:HGNC Symbol;Acc:HGNC:10340] | 29731 | -0.298 | -0.0133 | No |
| 24 | MRPS30 | mitochondrial ribosomal protein S30 [Source:HGNC Symbol;Acc:HGNC:8769] | 30647 | -0.525 | -0.0162 | No |
| 25 | RPL12 | ribosomal protein L12 [Source:HGNC Symbol;Acc:HGNC:10302] | 31019 | -0.619 | -0.0005 | No |
| 26 | RPL21 | ribosomal protein L21 [Source:HGNC Symbol;Acc:HGNC:10313] | 31128 | -0.651 | 0.0236 | No |
| 27 | PNRC2 | proline rich nuclear receptor coactivator 2 [Source:HGNC Symbol;Acc:HGNC:23158] | 31418 | -0.738 | 0.0465 | No |
| 28 | H3C4 | H3 clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4767] | 31879 | -0.867 | 0.0701 | No |
| 29 | RPL3 | ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10332] | 34170 | -1.698 | 0.0788 | No |
