Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_SMC4L1 |
| Enrichment Score (ES) | -0.7637351 |
| Normalized Enrichment Score (NES) | -1.599045 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.008089143 |
| FWER p-Value | 0.148 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAR1 | GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14264] | 931 | 2.240 | -0.0096 | No |
| 2 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 1754 | 1.519 | -0.0213 | No |
| 3 | DKC1 | dyskerin pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:2890] | 2488 | 1.134 | -0.0332 | No |
| 4 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265] | 2642 | 1.066 | -0.0299 | No |
| 5 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2837 | 0.990 | -0.0283 | No |
| 6 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 3308 | 0.797 | -0.0355 | No |
| 7 | SRSF1 | serine and arginine rich splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:10780] | 3419 | 0.766 | -0.0331 | No |
| 8 | NUP153 | nucleoporin 153 [Source:HGNC Symbol;Acc:HGNC:8062] | 3714 | 0.670 | -0.0364 | No |
| 9 | MRPL35 | mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489] | 3813 | 0.639 | -0.0346 | No |
| 10 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 15518 | 0.000 | -0.3509 | No |
| 11 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23551 | 0.000 | -0.5679 | No |
| 12 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 28591 | -0.018 | -0.7040 | No |
| 13 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 28955 | -0.111 | -0.7130 | No |
| 14 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 29197 | -0.176 | -0.7183 | No |
| 15 | SERBP1 | SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17860] | 29339 | -0.207 | -0.7207 | No |
| 16 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 29473 | -0.232 | -0.7226 | No |
| 17 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30062 | -0.369 | -0.7360 | No |
| 18 | ANP32B | acidic nuclear phosphoprotein 32 family member B [Source:HGNC Symbol;Acc:HGNC:16677] | 30136 | -0.388 | -0.7352 | No |
| 19 | COPS3 | COP9 signalosome subunit 3 [Source:HGNC Symbol;Acc:HGNC:2239] | 30908 | -0.592 | -0.7520 | No |
| 20 | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit [Source:HGNC Symbol;Acc:HGNC:11465] | 31046 | -0.627 | -0.7513 | No |
| 21 | ZWILCH | zwilch kinetochore protein [Source:HGNC Symbol;Acc:HGNC:25468] | 31242 | -0.686 | -0.7518 | No |
| 22 | HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13729] | 31370 | -0.725 | -0.7502 | No |
| 23 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 31619 | -0.774 | -0.7515 | No |
| 24 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 31689 | -0.798 | -0.7479 | No |
| 25 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32001 | -0.913 | -0.7499 | No |
| 26 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32513 | -1.089 | -0.7562 | Yes |
| 27 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 32575 | -1.108 | -0.7501 | Yes |
| 28 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 32582 | -1.110 | -0.7426 | Yes |
| 29 | USP1 | ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607] | 32614 | -1.123 | -0.7356 | Yes |
| 30 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 32901 | -1.221 | -0.7349 | Yes |
| 31 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 32933 | -1.233 | -0.7271 | Yes |
| 32 | EXOSC8 | exosome component 8 [Source:HGNC Symbol;Acc:HGNC:17035] | 33033 | -1.266 | -0.7210 | Yes |
| 33 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 33083 | -1.285 | -0.7134 | Yes |
| 34 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 33146 | -1.310 | -0.7060 | Yes |
| 35 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 33326 | -1.384 | -0.7012 | Yes |
| 36 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33400 | -1.422 | -0.6933 | Yes |
| 37 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 33419 | -1.430 | -0.6839 | Yes |
| 38 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 33442 | -1.442 | -0.6744 | Yes |
| 39 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 33445 | -1.443 | -0.6645 | Yes |
| 40 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 33571 | -1.451 | -0.6578 | Yes |
| 41 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33722 | -1.484 | -0.6515 | Yes |
| 42 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33797 | -1.517 | -0.6430 | Yes |
| 43 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 33799 | -1.519 | -0.6325 | Yes |
| 44 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34155 | -1.691 | -0.6303 | Yes |
| 45 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 34182 | -1.707 | -0.6191 | Yes |
| 46 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 34487 | -1.852 | -0.6145 | Yes |
| 47 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34488 | -1.854 | -0.6016 | Yes |
| 48 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 34533 | -1.882 | -0.5897 | Yes |
| 49 | DEK | DEK proto-oncogene [Source:HGNC Symbol;Acc:HGNC:2768] | 34556 | -1.897 | -0.5772 | Yes |
| 50 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 34662 | -1.944 | -0.5665 | Yes |
| 51 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 34669 | -1.947 | -0.5531 | Yes |
| 52 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34681 | -1.952 | -0.5399 | Yes |
| 53 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 34689 | -1.957 | -0.5265 | Yes |
| 54 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 34774 | -2.027 | -0.5147 | Yes |
| 55 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34782 | -2.033 | -0.5007 | Yes |
| 56 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 34879 | -2.099 | -0.4887 | Yes |
| 57 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 34909 | -2.119 | -0.4748 | Yes |
| 58 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 34919 | -2.126 | -0.4603 | Yes |
| 59 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35037 | -2.200 | -0.4482 | Yes |
| 60 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 35078 | -2.229 | -0.4338 | Yes |
| 61 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35185 | -2.308 | -0.4206 | Yes |
| 62 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35306 | -2.318 | -0.4077 | Yes |
| 63 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 35329 | -2.329 | -0.3922 | Yes |
| 64 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35520 | -2.493 | -0.3800 | Yes |
| 65 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35541 | -2.516 | -0.3630 | Yes |
| 66 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35567 | -2.531 | -0.3461 | Yes |
| 67 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35576 | -2.541 | -0.3287 | Yes |
| 68 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35581 | -2.547 | -0.3111 | Yes |
| 69 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 35708 | -2.647 | -0.2961 | Yes |
| 70 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 35725 | -2.658 | -0.2781 | Yes |
| 71 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 35742 | -2.678 | -0.2599 | Yes |
| 72 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 35814 | -2.749 | -0.2428 | Yes |
| 73 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 35839 | -2.770 | -0.2242 | Yes |
| 74 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 35850 | -2.788 | -0.2051 | Yes |
| 75 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 35994 | -2.919 | -0.1887 | Yes |
| 76 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 36112 | -3.054 | -0.1706 | Yes |
| 77 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36290 | -3.231 | -0.1529 | Yes |
| 78 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36367 | -3.347 | -0.1317 | Yes |
| 79 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36383 | -3.368 | -0.1088 | Yes |
| 80 | FBXO5 | F-box protein 5 [Source:HGNC Symbol;Acc:HGNC:13584] | 36456 | -3.450 | -0.0867 | Yes |
| 81 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36496 | -3.483 | -0.0636 | Yes |
| 82 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36693 | -3.791 | -0.0426 | Yes |
| 83 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36701 | -3.805 | -0.0163 | Yes |
| 84 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36724 | -3.858 | 0.0099 | Yes |
