Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | GOCC_PRERIBOSOME |
| Enrichment Score (ES) | 0.75127745 |
| Normalized Enrichment Score (NES) | 1.8226765 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.13436142 |
| FWER p-Value | 0.307 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PWP2 | PWP2 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:9711] | 130 | 4.210 | 0.0447 | Yes |
| 2 | BOP1 | BOP1 ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:15519] | 327 | 3.462 | 0.0791 | Yes |
| 3 | RSL1D1 | ribosomal L1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24534] | 479 | 2.984 | 0.1092 | Yes |
| 4 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 555 | 2.815 | 0.1394 | Yes |
| 5 | RIOK3 | RIO kinase 3 [Source:HGNC Symbol;Acc:HGNC:11451] | 567 | 2.794 | 0.1711 | Yes |
| 6 | RIOK2 | RIO kinase 2 [Source:HGNC Symbol;Acc:HGNC:18999] | 700 | 2.607 | 0.1974 | Yes |
| 7 | UTP23 | UTP23 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:28224] | 888 | 2.303 | 0.2187 | Yes |
| 8 | TSR1 | TSR1 ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:25542] | 957 | 2.203 | 0.2421 | Yes |
| 9 | HEATR1 | HEAT repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:25517] | 977 | 2.184 | 0.2666 | Yes |
| 10 | FP565260.1 | periodic tryptophan protein 2 homolog [Source:NCBI gene (formerly Entrezgene);Acc:102724159] | 1009 | 2.133 | 0.2902 | Yes |
| 11 | NOC4L | nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461] | 1051 | 2.085 | 0.3130 | Yes |
| 12 | UTP4 | UTP4 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:1983] | 1116 | 1.993 | 0.3341 | Yes |
| 13 | UTP20 | UTP20 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897] | 1207 | 1.887 | 0.3533 | Yes |
| 14 | MDN1 | midasin AAA ATPase 1 [Source:HGNC Symbol;Acc:HGNC:18302] | 1356 | 1.866 | 0.3707 | Yes |
| 15 | RRP9 | ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829] | 1367 | 1.850 | 0.3916 | Yes |
| 16 | NOP58 | NOP58 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:29926] | 1382 | 1.830 | 0.4122 | Yes |
| 17 | NIP7 | nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328] | 1465 | 1.734 | 0.4298 | Yes |
| 18 | UTP25 | UTP25 small subunit processor component [Source:HGNC Symbol;Acc:HGNC:28440] | 1506 | 1.705 | 0.4483 | Yes |
| 19 | WDR46 | WD repeat domain 46 [Source:HGNC Symbol;Acc:HGNC:13923] | 1538 | 1.678 | 0.4667 | Yes |
| 20 | PDCD11 | programmed cell death 11 [Source:HGNC Symbol;Acc:HGNC:13408] | 1749 | 1.521 | 0.4784 | Yes |
| 21 | BMS1 | BMS1 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:23505] | 1798 | 1.488 | 0.4942 | Yes |
| 22 | LTV1 | LTV1 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:21173] | 1850 | 1.463 | 0.5095 | Yes |
| 23 | RIOK1 | RIO kinase 1 [Source:HGNC Symbol;Acc:HGNC:18656] | 1878 | 1.442 | 0.5253 | Yes |
| 24 | NOL6 | nucleolar protein 6 [Source:HGNC Symbol;Acc:HGNC:19910] | 1893 | 1.428 | 0.5413 | Yes |
| 25 | MRTO4 | MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477] | 1903 | 1.419 | 0.5573 | Yes |
| 26 | NOL10 | nucleolar protein 10 [Source:HGNC Symbol;Acc:HGNC:25862] | 1969 | 1.377 | 0.5713 | Yes |
| 27 | EIF6 | eukaryotic translation initiation factor 6 [Source:HGNC Symbol;Acc:HGNC:6159] | 2145 | 1.269 | 0.5811 | Yes |
| 28 | WDR37 | WD repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:31406] | 2300 | 1.223 | 0.5910 | Yes |
| 29 | WDR12 | WD repeat domain 12 [Source:HGNC Symbol;Acc:HGNC:14098] | 2314 | 1.216 | 0.6046 | Yes |
| 30 | NOP14 | NOP14 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:16821] | 2319 | 1.212 | 0.6183 | Yes |
| 31 | RRP7BP | ribosomal RNA processing 7 homolog B, pseudogene [Source:HGNC Symbol;Acc:HGNC:30454] | 2359 | 1.192 | 0.6309 | Yes |
| 32 | EMG1 | EMG1 N1-specific pseudouridine methyltransferase [Source:HGNC Symbol;Acc:HGNC:16912] | 2505 | 1.127 | 0.6399 | Yes |
| 33 | EBNA1BP2 | EBNA1 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15531] | 2540 | 1.112 | 0.6517 | Yes |
| 34 | RRS1 | ribosome biogenesis regulator 1 homolog [Source:HGNC Symbol;Acc:HGNC:17083] | 2552 | 1.111 | 0.6642 | Yes |
| 35 | RRP36 | ribosomal RNA processing 36 [Source:HGNC Symbol;Acc:HGNC:21374] | 2680 | 1.054 | 0.6728 | Yes |
| 36 | BYSL | bystin like [Source:HGNC Symbol;Acc:HGNC:1157] | 2685 | 1.053 | 0.6848 | Yes |
| 37 | RPF1 | ribosome production factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:30350] | 2734 | 1.035 | 0.6953 | Yes |
| 38 | SNU13 | small nuclear ribonucleoprotein 13 [Source:HGNC Symbol;Acc:HGNC:7819] | 2756 | 1.023 | 0.7065 | Yes |
| 39 | FTSJ3 | FtsJ RNA 2'-O-methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:17136] | 2808 | 1.003 | 0.7166 | Yes |
| 40 | MPHOSPH10 | M-phase phosphoprotein 10 [Source:HGNC Symbol;Acc:HGNC:7213] | 2909 | 0.954 | 0.7248 | Yes |
| 41 | IMP4 | IMP U3 small nucleolar ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:30856] | 3164 | 0.855 | 0.7277 | Yes |
| 42 | DCAF13 | DDB1 and CUL4 associated factor 13 [Source:HGNC Symbol;Acc:HGNC:24535] | 3496 | 0.737 | 0.7272 | Yes |
| 43 | SRFBP1 | serum response factor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26333] | 3510 | 0.732 | 0.7353 | Yes |
| 44 | UTP6 | UTP6 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:18279] | 3580 | 0.709 | 0.7415 | Yes |
| 45 | NOP56 | NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911] | 3732 | 0.662 | 0.7450 | Yes |
| 46 | MAK16 | MAK16 homolog [Source:HGNC Symbol;Acc:HGNC:13703] | 3807 | 0.640 | 0.7504 | Yes |
| 47 | TBL3 | transducin beta like 3 [Source:HGNC Symbol;Acc:HGNC:11587] | 4282 | 0.494 | 0.7432 | Yes |
| 48 | RRP7A | ribosomal RNA processing 7 homolog A [Source:HGNC Symbol;Acc:HGNC:24286] | 4358 | 0.475 | 0.7466 | Yes |
| 49 | PES1 | pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8848] | 4386 | 0.469 | 0.7513 | Yes |
| 50 | XRCC5 | X-ray repair cross complementing 5 [Source:HGNC Symbol;Acc:HGNC:12833] | 4666 | 0.382 | 0.7481 | No |
| 51 | FBL | fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599] | 4758 | 0.356 | 0.7497 | No |
| 52 | RRP1B | ribosomal RNA processing 1B [Source:HGNC Symbol;Acc:HGNC:23818] | 4929 | 0.309 | 0.7487 | No |
| 53 | WDR74 | WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529] | 5718 | 0.186 | 0.7295 | No |
| 54 | KRR1 | KRR1 small subunit processome component homolog [Source:HGNC Symbol;Acc:HGNC:5176] | 5734 | 0.181 | 0.7312 | No |
| 55 | WDR36 | WD repeat domain 36 [Source:HGNC Symbol;Acc:HGNC:30696] | 5774 | 0.166 | 0.7320 | No |
| 56 | UTP11 | UTP11 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24329] | 5802 | 0.159 | 0.7331 | No |
| 57 | LAS1L | LAS1 like ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:25726] | 5808 | 0.158 | 0.7348 | No |
| 58 | NOP9 | NOP9 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:19826] | 5810 | 0.157 | 0.7366 | No |
| 59 | UTP14C | UTP14C small subunit processome component [Source:HGNC Symbol;Acc:HGNC:20321] | 5828 | 0.150 | 0.7378 | No |
| 60 | WDR3 | WD repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:12755] | 6146 | 0.057 | 0.7299 | No |
| 61 | UTP18 | UTP18 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24274] | 28647 | -0.034 | 0.1224 | No |
| 62 | NOC2L | NOC2 like nucleolar associated transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:24517] | 28786 | -0.068 | 0.1195 | No |
| 63 | KRI1 | KRI1 homolog [Source:HGNC Symbol;Acc:HGNC:25769] | 28846 | -0.082 | 0.1188 | No |
| 64 | UTP14A | UTP14A small subunit processome component [Source:HGNC Symbol;Acc:HGNC:10665] | 28863 | -0.087 | 0.1194 | No |
| 65 | NGDN | neuroguidin [Source:HGNC Symbol;Acc:HGNC:20271] | 28971 | -0.114 | 0.1178 | No |
| 66 | ZNF622 | zinc finger protein 622 [Source:HGNC Symbol;Acc:HGNC:30958] | 29425 | -0.221 | 0.1081 | No |
| 67 | RPS7 | ribosomal protein S7 [Source:HGNC Symbol;Acc:HGNC:10440] | 29466 | -0.230 | 0.1096 | No |
| 68 | PPAN | peter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227] | 29778 | -0.308 | 0.1048 | No |
| 69 | FBXW9 | F-box and WD repeat domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28136] | 30077 | -0.373 | 0.1010 | No |
| 70 | NSA2 | NSA2 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:30728] | 30172 | -0.402 | 0.1030 | No |
| 71 | FAM207A | family with sequence similarity 207 member A [Source:HGNC Symbol;Acc:HGNC:15811] | 30495 | -0.481 | 0.0998 | No |
| 72 | FCF1 | FCF1 rRNA-processing protein [Source:HGNC Symbol;Acc:HGNC:20220] | 30617 | -0.517 | 0.1025 | No |
| 73 | RRP1 | ribosomal RNA processing 1 [Source:HGNC Symbol;Acc:HGNC:18785] | 31097 | -0.644 | 0.0969 | No |
| 74 | NOB1 | NIN1 (RPN12) binding protein 1 homolog [Source:HGNC Symbol;Acc:HGNC:29540] | 31162 | -0.663 | 0.1028 | No |
| 75 | UTP3 | UTP3 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24477] | 31411 | -0.735 | 0.1045 | No |
| 76 | IMP3 | IMP U3 small nucleolar ribonucleoprotein 3 [Source:HGNC Symbol;Acc:HGNC:14497] | 31769 | -0.827 | 0.1044 | No |
| 77 | FBLL1 | fibrillarin like 1 [Source:HGNC Symbol;Acc:HGNC:35458] | 31922 | -0.881 | 0.1103 | No |
| 78 | PRKDC | protein kinase, DNA-activated, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9413] | 35589 | -2.554 | 0.0406 | No |
