Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | GOMF_CHEMOKINE_RECEPTOR_BINDING |
| Enrichment Score (ES) | 0.7453032 |
| Normalized Enrichment Score (NES) | 1.7541671 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.24501327 |
| FWER p-Value | 0.778 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 20 | 4.911 | 0.2053 | Yes |
| 2 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 56 | 4.661 | 0.3998 | Yes |
| 3 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 190 | 3.927 | 0.5608 | Yes |
| 4 | CXCL14 | C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640] | 1031 | 2.110 | 0.6266 | Yes |
| 5 | NARS1 | asparaginyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7643] | 1782 | 1.500 | 0.6692 | Yes |
| 6 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 1843 | 1.468 | 0.7291 | Yes |
| 7 | CNIH4 | cornichon family AMPA receptor auxiliary protein 4 [Source:HGNC Symbol;Acc:HGNC:25013] | 2804 | 1.005 | 0.7453 | Yes |
| 8 | CKLF | chemokine like factor [Source:HGNC Symbol;Acc:HGNC:13253] | 4134 | 0.539 | 0.7320 | No |
| 9 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 5635 | 0.213 | 0.7004 | No |
| 10 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6392 | 0.000 | 0.6800 | No |
| 11 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6393 | 0.000 | 0.6800 | No |
| 12 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6394 | 0.000 | 0.6800 | No |
| 13 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6413 | 0.000 | 0.6795 | No |
| 14 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6414 | 0.000 | 0.6795 | No |
| 15 | CCL17 | C-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:10615] | 6416 | 0.000 | 0.6795 | No |
| 16 | CCL16 | C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614] | 6417 | 0.000 | 0.6795 | No |
| 17 | CCL15 | C-C motif chemokine ligand 15 [Source:HGNC Symbol;Acc:HGNC:10613] | 6419 | 0.000 | 0.6795 | No |
| 18 | CCL25 | C-C motif chemokine ligand 25 [Source:HGNC Symbol;Acc:HGNC:10624] | 6420 | 0.000 | 0.6795 | No |
| 19 | CCL24 | C-C motif chemokine ligand 24 [Source:HGNC Symbol;Acc:HGNC:10623] | 6421 | 0.000 | 0.6795 | No |
| 20 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6423 | 0.000 | 0.6794 | No |
| 21 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6424 | 0.000 | 0.6794 | No |
| 22 | CCL21 | C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620] | 6425 | 0.000 | 0.6794 | No |
| 23 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6427 | 0.000 | 0.6794 | No |
| 24 | CCL28 | C-C motif chemokine ligand 28 [Source:HGNC Symbol;Acc:HGNC:17700] | 6444 | 0.000 | 0.6790 | No |
| 25 | CCL27 | C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626] | 6446 | 0.000 | 0.6789 | No |
| 26 | CCL26 | C-C motif chemokine ligand 26 [Source:HGNC Symbol;Acc:HGNC:10625] | 6448 | 0.000 | 0.6789 | No |
| 27 | DEFB4A | defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] | 7255 | 0.000 | 0.6571 | No |
| 28 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8858 | 0.000 | 0.6139 | No |
| 29 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10819 | 0.000 | 0.5609 | No |
| 30 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11060 | 0.000 | 0.5545 | No |
| 31 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 11228 | 0.000 | 0.5499 | No |
| 32 | MSMP | microseminoprotein, prostate associated [Source:HGNC Symbol;Acc:HGNC:29663] | 12432 | 0.000 | 0.5175 | No |
| 33 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14840 | 0.000 | 0.4524 | No |
| 34 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14842 | 0.000 | 0.4524 | No |
| 35 | XCL2 | X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10646] | 15849 | 0.000 | 0.4252 | No |
| 36 | XCL1 | X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645] | 15851 | 0.000 | 0.4252 | No |
| 37 | C5 | complement C5 [Source:HGNC Symbol;Acc:HGNC:1331] | 16103 | 0.000 | 0.4184 | No |
| 38 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18962 | 0.000 | 0.3412 | No |
| 39 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 19000 | 0.000 | 0.3402 | No |
| 40 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 19001 | 0.000 | 0.3402 | No |
| 41 | NES | nestin [Source:HGNC Symbol;Acc:HGNC:7756] | 19373 | 0.000 | 0.3302 | No |
| 42 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19548 | 0.000 | 0.3255 | No |
| 43 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19550 | 0.000 | 0.3255 | No |
| 44 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19553 | 0.000 | 0.3254 | No |
| 45 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19562 | 0.000 | 0.3252 | No |
| 46 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19564 | 0.000 | 0.3252 | No |
| 47 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19565 | 0.000 | 0.3252 | No |
| 48 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19567 | 0.000 | 0.3252 | No |
| 49 | DEFB1 | defensin beta 1 [Source:HGNC Symbol;Acc:HGNC:2766] | 20599 | 0.000 | 0.2973 | No |
| 50 | PF4V1 | platelet factor 4 variant 1 [Source:HGNC Symbol;Acc:HGNC:8862] | 24564 | 0.000 | 0.1902 | No |
| 51 | PF4 | platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861] | 24747 | 0.000 | 0.1853 | No |
| 52 | TFF2 | trefoil factor 2 [Source:HGNC Symbol;Acc:HGNC:11756] | 25489 | 0.000 | 0.1653 | No |
| 53 | DEFB109B | defensin beta 109B [Source:HGNC Symbol;Acc:HGNC:33469] | 25950 | 0.000 | 0.1529 | No |
| 54 | DEFB130A | defensin beta 130A [Source:HGNC Symbol;Acc:HGNC:18107] | 27060 | 0.000 | 0.1229 | No |
| 55 | DEFB130B | defensin beta 130B [Source:HGNC Symbol;Acc:HGNC:39814] | 27062 | 0.000 | 0.1229 | No |
| 56 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 28028 | 0.000 | 0.0968 | No |
| 57 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 28030 | 0.000 | 0.0968 | No |
| 58 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 28037 | 0.000 | 0.0967 | No |
| 59 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 28039 | 0.000 | 0.0966 | No |
| 60 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 28040 | 0.000 | 0.0966 | No |
| 61 | DEFB103A | defensin beta 103A [Source:HGNC Symbol;Acc:HGNC:15967] | 28087 | 0.000 | 0.0954 | No |
| 62 | DEFB103B | defensin beta 103B [Source:HGNC Symbol;Acc:HGNC:31702] | 28090 | 0.000 | 0.0953 | No |
| 63 | DEFB106B | defensin beta 106B [Source:HGNC Symbol;Acc:HGNC:28879] | 28149 | 0.000 | 0.0938 | No |
| 64 | DEFB106A | defensin beta 106A [Source:HGNC Symbol;Acc:HGNC:18088] | 28157 | 0.000 | 0.0936 | No |
| 65 | YARS1 | tyrosyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12840] | 28558 | -0.010 | 0.0832 | No |
| 66 | ITCH | itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890] | 28642 | -0.032 | 0.0823 | No |
| 67 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 33602 | -1.451 | 0.0091 | No |
| 68 | S100A14 | S100 calcium binding protein A14 [Source:HGNC Symbol;Acc:HGNC:18901] | 34775 | -2.028 | 0.0625 | No |
