Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | CSR_EARLY_UP.V1_DN |
| Enrichment Score (ES) | -0.6060415 |
| Normalized Enrichment Score (NES) | -1.3125689 |
| Nominal p-value | 0.03504673 |
| FDR q-value | 0.18665281 |
| FWER p-Value | 0.975 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 115 | 4.296 | 0.0261 | No |
| 2 | NR1H3 | nuclear receptor subfamily 1 group H member 3 [Source:HGNC Symbol;Acc:HGNC:7966] | 289 | 3.547 | 0.0456 | No |
| 3 | EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3290] | 543 | 2.844 | 0.0581 | No |
| 4 | MINDY1 | MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648] | 939 | 2.229 | 0.0625 | No |
| 5 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 1047 | 2.089 | 0.0739 | No |
| 6 | LRIG2 | leucine rich repeats and immunoglobulin like domains 2 [Source:HGNC Symbol;Acc:HGNC:20889] | 1048 | 2.087 | 0.0881 | No |
| 7 | TENT5C | terminal nucleotidyltransferase 5C [Source:HGNC Symbol;Acc:HGNC:24712] | 1222 | 1.876 | 0.0961 | No |
| 8 | ARL4D | ADP ribosylation factor like GTPase 4D [Source:HGNC Symbol;Acc:HGNC:656] | 1235 | 1.876 | 0.1086 | No |
| 9 | TRIM56 | tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028] | 1585 | 1.641 | 0.1103 | No |
| 10 | IP6K2 | inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313] | 1920 | 1.401 | 0.1108 | No |
| 11 | ZNF585B | zinc finger protein 585B [Source:HGNC Symbol;Acc:HGNC:30948] | 2219 | 1.227 | 0.1111 | No |
| 12 | GRHL1 | grainyhead like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:17923] | 3081 | 0.887 | 0.0938 | No |
| 13 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 3140 | 0.865 | 0.0981 | No |
| 14 | ZFYVE1 | zinc finger FYVE-type containing 1 [Source:HGNC Symbol;Acc:HGNC:13180] | 3618 | 0.699 | 0.0900 | No |
| 15 | LTN1 | listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082] | 3740 | 0.660 | 0.0912 | No |
| 16 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 3955 | 0.590 | 0.0894 | No |
| 17 | FBXO38 | F-box protein 38 [Source:HGNC Symbol;Acc:HGNC:28844] | 3989 | 0.583 | 0.0925 | No |
| 18 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 4277 | 0.496 | 0.0881 | No |
| 19 | RNF20 | ring finger protein 20 [Source:HGNC Symbol;Acc:HGNC:10062] | 4307 | 0.487 | 0.0906 | No |
| 20 | HEBP2 | heme binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15716] | 5201 | 0.239 | 0.0681 | No |
| 21 | ZNF500 | zinc finger protein 500 [Source:HGNC Symbol;Acc:HGNC:23716] | 5401 | 0.239 | 0.0643 | No |
| 22 | GTPBP8 | GTP binding protein 8 (putative) [Source:HGNC Symbol;Acc:HGNC:25007] | 5937 | 0.120 | 0.0507 | No |
| 23 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:16629] | 6711 | 0.000 | 0.0298 | No |
| 24 | DAAM2 | dishevelled associated activator of morphogenesis 2 [Source:HGNC Symbol;Acc:HGNC:18143] | 6992 | 0.000 | 0.0222 | No |
| 25 | ASPA | aspartoacylase [Source:HGNC Symbol;Acc:HGNC:756] | 7861 | 0.000 | -0.0013 | No |
| 26 | PMS2P1 | PMS1 homolog 2, mismatch repair system component pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9123] | 8006 | 0.000 | -0.0052 | No |
| 27 | PRRT2 | proline rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30500] | 8607 | 0.000 | -0.0214 | No |
| 28 | TDRD6 | tudor domain containing 6 [Source:HGNC Symbol;Acc:HGNC:21339] | 9228 | 0.000 | -0.0382 | No |
| 29 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 10381 | 0.000 | -0.0694 | No |
| 30 | GFRA1 | GDNF family receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4243] | 11333 | 0.000 | -0.0951 | No |
| 31 | ERAP2 | endoplasmic reticulum aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:29499] | 11597 | 0.000 | -0.1022 | No |
| 32 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 12908 | 0.000 | -0.1376 | No |
| 33 | GSDMB | gasdermin B [Source:HGNC Symbol;Acc:HGNC:23690] | 13220 | 0.000 | -0.1460 | No |
| 34 | CDRT4 | CMT1A duplicated region transcript 4 [Source:HGNC Symbol;Acc:HGNC:14383] | 13389 | 0.000 | -0.1506 | No |
| 35 | GDF5 | growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220] | 13452 | 0.000 | -0.1523 | No |
| 36 | PDE5A | phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784] | 13546 | 0.000 | -0.1548 | No |
| 37 | NYNRIN | NYN domain and retroviral integrase containing [Source:HGNC Symbol;Acc:HGNC:20165] | 14012 | 0.000 | -0.1674 | No |
| 38 | HOXA10 | homeobox A10 [Source:HGNC Symbol;Acc:HGNC:5100] | 14375 | 0.000 | -0.1772 | No |
| 39 | STOX1 | storkhead box 1 [Source:HGNC Symbol;Acc:HGNC:23508] | 15866 | 0.000 | -0.2175 | No |
| 40 | MAB21L1 | mab-21 like 1 [Source:HGNC Symbol;Acc:HGNC:6757] | 15874 | 0.000 | -0.2177 | No |
| 41 | SLC7A14 | solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326] | 16276 | 0.000 | -0.2285 | No |
| 42 | SLC9A7 | solute carrier family 9 member A7 [Source:HGNC Symbol;Acc:HGNC:17123] | 17606 | 0.000 | -0.2645 | No |
| 43 | PAPLN | papilin, proteoglycan like sulfated glycoprotein [Source:HGNC Symbol;Acc:HGNC:19262] | 17965 | 0.000 | -0.2741 | No |
| 44 | C14orf132 | chromosome 14 open reading frame 132 [Source:HGNC Symbol;Acc:HGNC:20346] | 17985 | 0.000 | -0.2747 | No |
| 45 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18511 | 0.000 | -0.2889 | No |
| 46 | CAVIN2 | caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690] | 20805 | 0.000 | -0.3509 | No |
| 47 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 23042 | 0.000 | -0.4114 | No |
| 48 | SNPH | syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931] | 23214 | 0.000 | -0.4160 | No |
| 49 | NSUN5P2 | NSUN5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16609] | 23415 | 0.000 | -0.4214 | No |
| 50 | PLCD1 | phospholipase C delta 1 [Source:HGNC Symbol;Acc:HGNC:9060] | 23466 | 0.000 | -0.4228 | No |
| 51 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 24714 | 0.000 | -0.4565 | No |
| 52 | SAG | S-antigen visual arrestin [Source:HGNC Symbol;Acc:HGNC:10521] | 25607 | 0.000 | -0.4806 | No |
| 53 | SULF1 | sulfatase 1 [Source:HGNC Symbol;Acc:HGNC:20391] | 26819 | 0.000 | -0.5134 | No |
| 54 | ZNF33A | zinc finger protein 33A [Source:HGNC Symbol;Acc:HGNC:13096] | 27563 | 0.000 | -0.5335 | No |
| 55 | ZNF337 | zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809] | 27569 | 0.000 | -0.5336 | No |
| 56 | ZNF302 | zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848] | 27616 | 0.000 | -0.5349 | No |
| 57 | CYP2R1 | cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580] | 27824 | 0.000 | -0.5405 | No |
| 58 | CC2D1A | coiled-coil and C2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:30237] | 28527 | -0.003 | -0.5594 | No |
| 59 | ZFP64 | ZFP64 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:15940] | 28552 | -0.009 | -0.5600 | No |
| 60 | FBXO25 | F-box protein 25 [Source:HGNC Symbol;Acc:HGNC:13596] | 28555 | -0.009 | -0.5600 | No |
| 61 | RABGAP1 | RAB GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:17155] | 28588 | -0.018 | -0.5608 | No |
| 62 | SLC25A46 | solute carrier family 25 member 46 [Source:HGNC Symbol;Acc:HGNC:25198] | 28839 | -0.080 | -0.5670 | No |
| 63 | KBTBD6 | kelch repeat and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:25340] | 28983 | -0.119 | -0.5701 | No |
| 64 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 29267 | -0.190 | -0.5764 | No |
| 65 | TFAP2A | transcription factor AP-2 alpha [Source:HGNC Symbol;Acc:HGNC:11742] | 29487 | -0.238 | -0.5807 | No |
| 66 | NDNF | neuron derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:26256] | 29640 | -0.274 | -0.5830 | No |
| 67 | DXO | decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992] | 30042 | -0.364 | -0.5913 | No |
| 68 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 30314 | -0.436 | -0.5957 | No |
| 69 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 30370 | -0.453 | -0.5941 | No |
| 70 | USP33 | ubiquitin specific peptidase 33 [Source:HGNC Symbol;Acc:HGNC:20059] | 30372 | -0.454 | -0.5910 | No |
| 71 | PHIP | pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673] | 30638 | -0.523 | -0.5947 | No |
| 72 | MSRB1 | methionine sulfoxide reductase B1 [Source:HGNC Symbol;Acc:HGNC:14133] | 30758 | -0.556 | -0.5941 | No |
| 73 | ALDH1L2 | aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777] | 30930 | -0.597 | -0.5947 | No |
| 74 | ALDH3B2 | aldehyde dehydrogenase 3 family member B2 [Source:HGNC Symbol;Acc:HGNC:411] | 30937 | -0.599 | -0.5908 | No |
| 75 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 31105 | -0.646 | -0.5909 | No |
| 76 | CROCCP2 | CROCC pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:28170] | 31598 | -0.769 | -0.5990 | Yes |
| 77 | STX16 | syntaxin 16 [Source:HGNC Symbol;Acc:HGNC:11431] | 31615 | -0.774 | -0.5941 | Yes |
| 78 | ACBD4 | acyl-CoA binding domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23337] | 31882 | -0.868 | -0.5954 | Yes |
| 79 | ADAMTSL4 | ADAMTS like 4 [Source:HGNC Symbol;Acc:HGNC:19706] | 32079 | -0.936 | -0.5944 | Yes |
| 80 | BRD8 | bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874] | 32512 | -1.089 | -0.5986 | Yes |
| 81 | ELMOD3 | ELMO domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26158] | 32534 | -1.095 | -0.5918 | Yes |
| 82 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 32549 | -1.100 | -0.5846 | Yes |
| 83 | ABCC10 | ATP binding cassette subfamily C member 10 [Source:HGNC Symbol;Acc:HGNC:52] | 32634 | -1.129 | -0.5792 | Yes |
| 84 | LDB1 | LIM domain binding 1 [Source:HGNC Symbol;Acc:HGNC:6532] | 32902 | -1.222 | -0.5782 | Yes |
| 85 | NDUFAF7 | NADH:ubiquinone oxidoreductase complex assembly factor 7 [Source:HGNC Symbol;Acc:HGNC:28816] | 32910 | -1.225 | -0.5700 | Yes |
| 86 | MOSPD2 | motile sperm domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28381] | 33050 | -1.275 | -0.5651 | Yes |
| 87 | TCAIM | T cell activation inhibitor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25241] | 33098 | -1.292 | -0.5576 | Yes |
| 88 | AKIP1 | A-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1170] | 33278 | -1.367 | -0.5531 | Yes |
| 89 | DDX17 | DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740] | 33329 | -1.385 | -0.5451 | Yes |
| 90 | UBN2 | ubinuclein 2 [Source:HGNC Symbol;Acc:HGNC:21931] | 33347 | -1.396 | -0.5360 | Yes |
| 91 | PAN2 | poly(A) specific ribonuclease subunit PAN2 [Source:HGNC Symbol;Acc:HGNC:20074] | 33865 | -1.543 | -0.5395 | Yes |
| 92 | NMT2 | N-myristoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:7858] | 33938 | -1.581 | -0.5307 | Yes |
| 93 | ZNF467 | zinc finger protein 467 [Source:HGNC Symbol;Acc:HGNC:23154] | 33944 | -1.584 | -0.5201 | Yes |
| 94 | C2CD5 | C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062] | 33948 | -1.585 | -0.5093 | Yes |
| 95 | ANKZF1 | ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:25527] | 33957 | -1.589 | -0.4988 | Yes |
| 96 | POLL | DNA polymerase lambda [Source:HGNC Symbol;Acc:HGNC:9184] | 34045 | -1.641 | -0.4899 | Yes |
| 97 | UFSP2 | UFM1 specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:25640] | 34118 | -1.671 | -0.4805 | Yes |
| 98 | LRRK2 | leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618] | 34233 | -1.734 | -0.4718 | Yes |
| 99 | LRIG3 | leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991] | 34256 | -1.746 | -0.4605 | Yes |
| 100 | SIX5 | SIX homeobox 5 [Source:HGNC Symbol;Acc:HGNC:10891] | 34467 | -1.841 | -0.4537 | Yes |
| 101 | SIX1 | SIX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10887] | 35057 | -2.214 | -0.4546 | Yes |
| 102 | CDKN1B | cyclin dependent kinase inhibitor 1B [Source:HGNC Symbol;Acc:HGNC:1785] | 35125 | -2.268 | -0.4410 | Yes |
| 103 | CKB | creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991] | 35129 | -2.270 | -0.4256 | Yes |
| 104 | ING4 | inhibitor of growth family member 4 [Source:HGNC Symbol;Acc:HGNC:19423] | 35144 | -2.278 | -0.4105 | Yes |
| 105 | HBP1 | HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200] | 35149 | -2.282 | -0.3951 | Yes |
| 106 | MRI1 | methylthioribose-1-phosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:28469] | 35206 | -2.315 | -0.3808 | Yes |
| 107 | ACYP1 | acylphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:179] | 35226 | -2.316 | -0.3656 | Yes |
| 108 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 35449 | -2.436 | -0.3550 | Yes |
| 109 | CIRBP | cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982] | 35564 | -2.528 | -0.3409 | Yes |
| 110 | ATF7IP | activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092] | 35588 | -2.554 | -0.3241 | Yes |
| 111 | ACCS | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) [Source:HGNC Symbol;Acc:HGNC:23989] | 35673 | -2.614 | -0.3086 | Yes |
| 112 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 35705 | -2.646 | -0.2915 | Yes |
| 113 | ZNF226 | zinc finger protein 226 [Source:HGNC Symbol;Acc:HGNC:13019] | 35764 | -2.692 | -0.2747 | Yes |
| 114 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 35808 | -2.743 | -0.2572 | Yes |
| 115 | DCP1B | decapping mRNA 1B [Source:HGNC Symbol;Acc:HGNC:24451] | 35863 | -2.794 | -0.2397 | Yes |
| 116 | YEATS2 | YEATS domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25489] | 35943 | -2.857 | -0.2224 | Yes |
| 117 | MPPE1 | metallophosphoesterase 1 [Source:HGNC Symbol;Acc:HGNC:15988] | 36033 | -2.964 | -0.2046 | Yes |
| 118 | FUT10 | fucosyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19234] | 36060 | -2.988 | -0.1850 | Yes |
| 119 | ARRDC3 | arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263] | 36557 | -3.585 | -0.1740 | Yes |
| 120 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 36578 | -3.612 | -0.1500 | Yes |
| 121 | SLC16A7 | solute carrier family 16 member 7 [Source:HGNC Symbol;Acc:HGNC:10928] | 36649 | -3.721 | -0.1266 | Yes |
| 122 | NATD1 | N-acetyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30770] | 36690 | -3.791 | -0.1019 | Yes |
| 123 | AMT | aminomethyltransferase [Source:HGNC Symbol;Acc:HGNC:473] | 36778 | -3.960 | -0.0773 | Yes |
| 124 | NPHP3 | nephrocystin 3 [Source:HGNC Symbol;Acc:HGNC:7907] | 36796 | -4.000 | -0.0506 | Yes |
| 125 | OTUD1 | OTU deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:27346] | 36841 | -4.091 | -0.0239 | Yes |
| 126 | FZD2 | frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040] | 36991 | -4.502 | 0.0027 | Yes |
